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The map label for this gene is glpA-1 [H]

Identifier: 116328274

GI number: 116328274

Start: 1880203

End: 1881855

Strand: Reverse

Name: glpA-1 [H]

Synonym: LBL_1605

Alternate gene names: 116328274

Gene position: 1881855-1880203 (Counterclockwise)

Preceding gene: 116328277

Following gene: 116328267

Centisome position: 52.06

GC content: 42.23

Gene sequence:

>1653_bases
ATGCAAATATGTAGGGGGAAAGAAACCTGTAAAGCAGGAAGAGTTCTCAAAATGGAAAAACAAAACCGAACTGAACAAAT
TTTAAAATTACAAAAAGAATCCCTAGATATTCTCATAATTGGAGGCGGGTCCACCGGAACCGGAGCTGCCTTCGACGCCG
CGAAAAGAGGCTATAAAACAGCCCTCATAGAAAAGAAAGATTTTGCCTCGGGAACTTCCTCCCGTTCTACCAAACTGATT
CATGGAGGAGTCCGTTATCTGGCTCAGTTTCATTTCAAATTGATCCACGAAGCTCTGACAGAAAGACAAAAACTTTTGGA
AAACGCACCTCACTTGGTGAAACCTCTTAAGTTCTTGCTTCCAGCGTATCGTTTTTACGAAAAGCCTTATTACGGAATCG
GTCTCACTCTCTATGATATACTCGCTTCTAAGGGAAAACTTCCCTCTCATAAAACCGTTTCCAAATCTGAAGCCGTTTCC
GAATTTGCAGCAATCAAAAAAGAAGGCCTCTTCGGAGGAATCACATACTACGACGCTCAATTCAACGACGCCCGGTTGAA
CGTTCTTCTTGCAAGATCCGCTAAAAAAGAAGGAGCCATTGTCGCCAATCGAGTCGAACTTGTTTCCTTCATCAAGGAGA
ATGGAAGACTCATGGGCGCTAACCTCAAGGATTTGGAAACCGGAAAAAACTTTCCGGTCTATGCAAAGGTAATTGCGAAT
ACGACTGGAATTTGGGTGGATCACGTCCGCAAACTGGATGATTCAAGAGCGTTTAACGTTCTTTCTCCGAGTCAGGGAAT
CCATCTTGTCTTTTCTAAAAAAAAGATTCCCTGCCAATCGGCGATAATCATTCCCAAAACAAAGGACGGAAGAGTCGTCT
TTATCATTCCTTGGGAAAATCACGTAATTTTAGGAACGACGGATACTCCGATTGAAAATCCGGGAGACGAACCTCTTCCG
ATCGGAAACGAGGTTCAATTCTTACTCGATACCGGAAACGAATATCTGGAAAATCCAGTCACTGAAAAAGATATTCTTGC
CGTGTTTGCGGGGATCCGCCCTTTGATTTCTCCGGAAGGAAATCAGGACACTAAGAATATTTCGAGAGAGGAAGTTATCC
TCGTCTCCAATTCCGGCCTGGTCACAATGGGTGGGGGAAAATGGTCTACTTACAGAAAGATGGCTGAAGATCTAGTAGAT
AAACTAATTCAAGTTGGTAATTTAGAAATCAGGAAAGAATGTTCCACGAAATCTTACTTGTATCCCGGGGCCGAAGGTTA
TTCCGAGTCTCTCTATCAAGAAATTGAAAAATCGTATAAGATTGATACGGAACTCGCCAAAAGGTTACAAAATTATTACG
GGACGGAAGTTTTTGAGATCTTAGGTAAAAAGCCGAAACTTTTAGGCAAAGGTATCCCTTACTTTGAAGAGGAAGTTTTG
TTCGCTGCAAAGGAAGAATTTGCATTAGGCGTTACAGATGTTTTGGCGAGAAGATTCAGGGTTCTTTTTGTGGATTTAGA
TCTGGCGAAAAAGATGATAGAGCCCGTTGCGGGCATACTGTCCAAACAGCTCAAATGGAATAACAAAACAAAAAAAGCGG
AAGAATCCGCAACCTTGGAACTGATCGAAAGTTTGAAAAATTCGTATCGATGA

Upstream 100 bases:

>100_bases
ATTCGTCTTCGCTGATCAGATCAACGGTACCACGACGGATGATTTCTATTTGCTTTTGAATGTCCATGAAAGAAAAATCC
GGATTGGATTGTGAAACTTA

Downstream 100 bases:

>100_bases
CGAAAGCGAAACTTAGAATATTAGAAATATCTAATTTTAAAATGAGGAATTTCCGTCGCAGTTCCGAAGACAAACATAAT
AGCTACAGAGAAACCCCTTC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MQICRGKETCKAGRVLKMEKQNRTEQILKLQKESLDILIIGGGSTGTGAAFDAAKRGYKTALIEKKDFASGTSSRSTKLI
HGGVRYLAQFHFKLIHEALTERQKLLENAPHLVKPLKFLLPAYRFYEKPYYGIGLTLYDILASKGKLPSHKTVSKSEAVS
EFAAIKKEGLFGGITYYDAQFNDARLNVLLARSAKKEGAIVANRVELVSFIKENGRLMGANLKDLETGKNFPVYAKVIAN
TTGIWVDHVRKLDDSRAFNVLSPSQGIHLVFSKKKIPCQSAIIIPKTKDGRVVFIIPWENHVILGTTDTPIENPGDEPLP
IGNEVQFLLDTGNEYLENPVTEKDILAVFAGIRPLISPEGNQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVD
KLIQVGNLEIRKECSTKSYLYPGAEGYSESLYQEIEKSYKIDTELAKRLQNYYGTEVFEILGKKPKLLGKGIPYFEEEVL
FAAKEEFALGVTDVLARRFRVLFVDLDLAKKMIEPVAGILSKQLKWNNKTKKAEESATLELIESLKNSYR

Sequences:

>Translated_550_residues
MQICRGKETCKAGRVLKMEKQNRTEQILKLQKESLDILIIGGGSTGTGAAFDAAKRGYKTALIEKKDFASGTSSRSTKLI
HGGVRYLAQFHFKLIHEALTERQKLLENAPHLVKPLKFLLPAYRFYEKPYYGIGLTLYDILASKGKLPSHKTVSKSEAVS
EFAAIKKEGLFGGITYYDAQFNDARLNVLLARSAKKEGAIVANRVELVSFIKENGRLMGANLKDLETGKNFPVYAKVIAN
TTGIWVDHVRKLDDSRAFNVLSPSQGIHLVFSKKKIPCQSAIIIPKTKDGRVVFIIPWENHVILGTTDTPIENPGDEPLP
IGNEVQFLLDTGNEYLENPVTEKDILAVFAGIRPLISPEGNQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVD
KLIQVGNLEIRKECSTKSYLYPGAEGYSESLYQEIEKSYKIDTELAKRLQNYYGTEVFEILGKKPKLLGKGIPYFEEEVL
FAAKEEFALGVTDVLARRFRVLFVDLDLAKKMIEPVAGILSKQLKWNNKTKKAEESATLELIESLKNSYR
>Mature_550_residues
MQICRGKETCKAGRVLKMEKQNRTEQILKLQKESLDILIIGGGSTGTGAAFDAAKRGYKTALIEKKDFASGTSSRSTKLI
HGGVRYLAQFHFKLIHEALTERQKLLENAPHLVKPLKFLLPAYRFYEKPYYGIGLTLYDILASKGKLPSHKTVSKSEAVS
EFAAIKKEGLFGGITYYDAQFNDARLNVLLARSAKKEGAIVANRVELVSFIKENGRLMGANLKDLETGKNFPVYAKVIAN
TTGIWVDHVRKLDDSRAFNVLSPSQGIHLVFSKKKIPCQSAIIIPKTKDGRVVFIIPWENHVILGTTDTPIENPGDEPLP
IGNEVQFLLDTGNEYLENPVTEKDILAVFAGIRPLISPEGNQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVD
KLIQVGNLEIRKECSTKSYLYPGAEGYSESLYQEIEKSYKIDTELAKRLQNYYGTEVFEILGKKPKLLGKGIPYFEEEVL
FAAKEEFALGVTDVLARRFRVLFVDLDLAKKMIEPVAGILSKQLKWNNKTKKAEESATLELIESLKNSYR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=542, Percent_Identity=40.0369003690037, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI285002231, Length=542, Percent_Identity=40.0369003690037, Blast_Score=416, Evalue=1e-116,
Organism=Escherichia coli, GI2367226, Length=461, Percent_Identity=31.6702819956616, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1788574, Length=391, Percent_Identity=26.8542199488491, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17509253, Length=560, Percent_Identity=37.1428571428571, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI115534726, Length=521, Percent_Identity=37.4280230326296, Blast_Score=352, Evalue=3e-97,
Organism=Saccharomyces cerevisiae, GI6322036, Length=594, Percent_Identity=32.996632996633, Blast_Score=303, Evalue=6e-83,
Organism=Drosophila melanogaster, GI161077125, Length=546, Percent_Identity=38.0952380952381, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24653942, Length=546, Percent_Identity=38.0952380952381, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24653944, Length=546, Percent_Identity=38.0952380952381, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI20130025, Length=546, Percent_Identity=38.0952380952381, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24586295, Length=553, Percent_Identity=33.0922242314647, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI19921278, Length=563, Percent_Identity=30.9058614564831, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI45550977, Length=398, Percent_Identity=27.8894472361809, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61481; Mature: 61481

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQICRGKETCKAGRVLKMEKQNRTEQILKLQKESLDILIIGGGSTGTGAAFDAAKRGYKT
CCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHH
ALIEKKDFASGTSSRSTKLIHGGVRYLAQFHFKLIHEALTERQKLLENAPHLVKPLKFLL
HEECCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PAYRFYEKPYYGIGLTLYDILASKGKLPSHKTVSKSEAVSEFAAIKKEGLFGGITYYDAQ
HHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
FNDARLNVLLARSAKKEGAIVANRVELVSFIKENGRLMGANLKDLETGKNFPVYAKVIAN
CCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCCEEEECCCHHHCCCCCCCEEEEEHHC
TTGIWVDHVRKLDDSRAFNVLSPSQGIHLVFSKKKIPCQSAIIIPKTKDGRVVFIIPWEN
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCC
HVILGTTDTPIENPGDEPLPIGNEVQFLLDTGNEYLENPVTEKDILAVFAGIRPLISPEG
EEEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHCCCCCCCCCC
NQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVDKLIQVGNLEIRKECSTKSYL
CCHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEE
YPGAEGYSESLYQEIEKSYKIDTELAKRLQNYYGTEVFEILGKKPKLLGKGIPYFEEEVL
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCHHHCCCCCCHHHHHH
FAAKEEFALGVTDVLARRFRVLFVDLDLAKKMIEPVAGILSKQLKWNNKTKKAEESATLE
HHHHHHHHCCHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LIESLKNSYR
HHHHHHHCCC
>Mature Secondary Structure
MQICRGKETCKAGRVLKMEKQNRTEQILKLQKESLDILIIGGGSTGTGAAFDAAKRGYKT
CCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHH
ALIEKKDFASGTSSRSTKLIHGGVRYLAQFHFKLIHEALTERQKLLENAPHLVKPLKFLL
HEECCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PAYRFYEKPYYGIGLTLYDILASKGKLPSHKTVSKSEAVSEFAAIKKEGLFGGITYYDAQ
HHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
FNDARLNVLLARSAKKEGAIVANRVELVSFIKENGRLMGANLKDLETGKNFPVYAKVIAN
CCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCCEEEECCCHHHCCCCCCCEEEEEHHC
TTGIWVDHVRKLDDSRAFNVLSPSQGIHLVFSKKKIPCQSAIIIPKTKDGRVVFIIPWEN
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCC
HVILGTTDTPIENPGDEPLPIGNEVQFLLDTGNEYLENPVTEKDILAVFAGIRPLISPEG
EEEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHCCCCCCCCCC
NQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVDKLIQVGNLEIRKECSTKSYL
CCHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEE
YPGAEGYSESLYQEIEKSYKIDTELAKRLQNYYGTEVFEILGKKPKLLGKGIPYFEEEVL
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCHHHCCCCCCHHHHHH
FAAKEEFALGVTDVLARRFRVLFVDLDLAKKMIEPVAGILSKQLKWNNKTKKAEESATLE
HHHHHHHHCCHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LIESLKNSYR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]