Click here to switch to the map view.

The map label for this gene is 116328077

Identifier: 116328077

GI number: 116328077

Start: 1605828

End: 1607741

Strand: Direct

Name: 116328077

Synonym: LBL_1374

Alternate gene names: NA

Gene position: 1605828-1607741 (Clockwise)

Preceding gene: 116328076

Following gene: 116328079

Centisome position: 44.43

GC content: 43.99

Gene sequence:

>1914_bases
TTGAAAGAAAGAAAATTTTCCAGCTCGATCGAGGAGTTGGAATTTGTTCGGGCTGAACTCGAAAGGGAAAAAAAAGAAGA
GGGTTTCCTCTTTTCCAAAGACTGGCTTTCCCGTTCTCTCCAAGACCGGATTAAGCTCGGAATCGCGTTATACCCTCTTG
TCTACGAAGAACAGTCTTTTGGTAGAGGAGGAAGTTGGATCCTTACCTTTCGTTTTCCGAATCAAGAGGAATATCCGTCT
AAATTTCAGCCCGGCGCTCTGGTTCAAATAGGAAAGAACGAAGATAGGGTTCGGGCCATATTAGTTTCTCTTCATAAAGA
AAGAATTCGGATCGCGATCGAGGAAGTCCCGGAATGGATCGAAGACGGAAAATGTTTTTTAGATCTTCTTCCCGATGAAA
CCTCCTACAAAGAAATGTTATACGCGTTAGACGCAGTTTCATCTGCTCCCAAAGGAACGAGGTTATATGTCAATCGCGAG
CTTTTATTAGGCTACGGGAAACCGGATCCGATCGCGATTCGAAAATCTGATGAAACCCGAATATTGCAAAGATTGAATTC
TTCTTTGAATCCATCGCAGAAAAATGCGGTTTTGCGTTGTGTTCTTTCCGAGGATATTGCTGTAATTCACGGGCCTCCCG
GTACAGGAAAAACAACCACATTAACCGAAATAATTAGTCAGATCGTAGCGGAAGAAAAAAAGGTTCTTGTGTCCGCTCCC
ACACATTCCGCTTGCGATCTTTTGGTCGAATCGATCTCAGCGAAAGGAATTTCGGTTTTACGTCTGGGGCATCCCGCGCG
TATTAGTGATACGGCGCTTCATACAACCCTCGACTACAAACTTTTTCATCATTCCGACGGAAAATTGTTAAACGAATACA
GAAGAGACGTGATCGAAATCTCGAAACAAGCTAAAAAATATAAACGTAACTTCGGAGAAAAAGAGAAGGAAGATCGTAAG
AATCTTTTTCAGGAAGTCAAAGAACTCAAAAAGACGATCCGATCCATGGAAAAGGGACTGATAGATAGTTTGATTTCCTC
TCATTCCGTGATCGTTTCCACTCCCGTCGCTTCCGCTCGTTCCGTTTTGGAGGGAAGAAGGTTCGACTTTTGCGTGTTAG
ACGAATCGTCTCAGGCTCTCGAACCCGCGACCTGGATTCCAATTTTGAAATCGGATCGAGTGATTCTTGCGGGGGATCAT
AAGCAGTTGCCGCCTACTTTATTTTCAGAAAAAAATTCTCTGGAGTTTACACTTTTTGAAAAAGCCGCGGAAAGATTGGA
AACGTCCGGGCGGGTTTTTATGCTTGATACTCAGTATAGAATGAAGGACGAGATCGCCTCTTTCCCTTCCATGGAATTTT
ATTCGAATCGACTGAAGTCAGGCCGTCCGGGACCGGAAAAAATTTCCAACTTTCCGAAAACTTTCCCTTTCAGAGATGCA
CTCCAATGGATCGATACAGCCGGGACCGACAGCGAGGAAGTCGCTGTTGACGATAGTCTTACTAATCCTTTCGAAGCGGA
TCTTCAGGTTCGTCTTTGTACTTTACTTCAAGAGAACAACTGGCCCGAAGAAGAGATTACGATTCTTTCTCCGTATCGTG
CTCAGGTGCGATTGCTTTCGGAAAAATTACAGGAAGCAGGGCTTTCTAAAATCCAAGTCTCTACGATAGACTCGTTTCAA
GGAAGAGAGAATCGTTGTATTTTTCTCGGGTTTGTCCGTTCCAATTCGGAAGGTCGTTCCGGTTTTTTAAAGGAATCCAG
AAGAATCAACGTCGGTATGACGAGAGCCAAGGACCTTTTGCTTTGTATCGGCGATAGCTCCACTCTTTTGGAGGATCCTT
TTCTCTCTAGGTTCATTCGATTTATAGAAGAGAAAAAATTCTTTCGGACTGCCTGGGAATTTCGCGATCCATAG

Upstream 100 bases:

>100_bases
CTACTCTTGCGAGCGCGATTCGATTTGCGGAAGGACTCCCCATAAGAGGCGATCAAAAATCCCAGGTCTACAGAATCGTA
GTCCTTTCTCCCGATCGGTT

Downstream 100 bases:

>100_bases
AGAGCGAAATTGCCAGCGAACAGCGGAGCATTACCAAGCGATCCCTAGAGAGCCATAACGTTACCCACAAGTTAAGAAGG
CTTTTGGGATCATAAGGATC

Product: DNA and RNA helicase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MKERKFSSSIEELEFVRAELEREKKEEGFLFSKDWLSRSLQDRIKLGIALYPLVYEEQSFGRGGSWILTFRFPNQEEYPS
KFQPGALVQIGKNEDRVRAILVSLHKERIRIAIEEVPEWIEDGKCFLDLLPDETSYKEMLYALDAVSSAPKGTRLYVNRE
LLLGYGKPDPIAIRKSDETRILQRLNSSLNPSQKNAVLRCVLSEDIAVIHGPPGTGKTTTLTEIISQIVAEEKKVLVSAP
THSACDLLVESISAKGISVLRLGHPARISDTALHTTLDYKLFHHSDGKLLNEYRRDVIEISKQAKKYKRNFGEKEKEDRK
NLFQEVKELKKTIRSMEKGLIDSLISSHSVIVSTPVASARSVLEGRRFDFCVLDESSQALEPATWIPILKSDRVILAGDH
KQLPPTLFSEKNSLEFTLFEKAAERLETSGRVFMLDTQYRMKDEIASFPSMEFYSNRLKSGRPGPEKISNFPKTFPFRDA
LQWIDTAGTDSEEVAVDDSLTNPFEADLQVRLCTLLQENNWPEEEITILSPYRAQVRLLSEKLQEAGLSKIQVSTIDSFQ
GRENRCIFLGFVRSNSEGRSGFLKESRRINVGMTRAKDLLLCIGDSSTLLEDPFLSRFIRFIEEKKFFRTAWEFRDP

Sequences:

>Translated_637_residues
MKERKFSSSIEELEFVRAELEREKKEEGFLFSKDWLSRSLQDRIKLGIALYPLVYEEQSFGRGGSWILTFRFPNQEEYPS
KFQPGALVQIGKNEDRVRAILVSLHKERIRIAIEEVPEWIEDGKCFLDLLPDETSYKEMLYALDAVSSAPKGTRLYVNRE
LLLGYGKPDPIAIRKSDETRILQRLNSSLNPSQKNAVLRCVLSEDIAVIHGPPGTGKTTTLTEIISQIVAEEKKVLVSAP
THSACDLLVESISAKGISVLRLGHPARISDTALHTTLDYKLFHHSDGKLLNEYRRDVIEISKQAKKYKRNFGEKEKEDRK
NLFQEVKELKKTIRSMEKGLIDSLISSHSVIVSTPVASARSVLEGRRFDFCVLDESSQALEPATWIPILKSDRVILAGDH
KQLPPTLFSEKNSLEFTLFEKAAERLETSGRVFMLDTQYRMKDEIASFPSMEFYSNRLKSGRPGPEKISNFPKTFPFRDA
LQWIDTAGTDSEEVAVDDSLTNPFEADLQVRLCTLLQENNWPEEEITILSPYRAQVRLLSEKLQEAGLSKIQVSTIDSFQ
GRENRCIFLGFVRSNSEGRSGFLKESRRINVGMTRAKDLLLCIGDSSTLLEDPFLSRFIRFIEEKKFFRTAWEFRDP
>Mature_637_residues
MKERKFSSSIEELEFVRAELEREKKEEGFLFSKDWLSRSLQDRIKLGIALYPLVYEEQSFGRGGSWILTFRFPNQEEYPS
KFQPGALVQIGKNEDRVRAILVSLHKERIRIAIEEVPEWIEDGKCFLDLLPDETSYKEMLYALDAVSSAPKGTRLYVNRE
LLLGYGKPDPIAIRKSDETRILQRLNSSLNPSQKNAVLRCVLSEDIAVIHGPPGTGKTTTLTEIISQIVAEEKKVLVSAP
THSACDLLVESISAKGISVLRLGHPARISDTALHTTLDYKLFHHSDGKLLNEYRRDVIEISKQAKKYKRNFGEKEKEDRK
NLFQEVKELKKTIRSMEKGLIDSLISSHSVIVSTPVASARSVLEGRRFDFCVLDESSQALEPATWIPILKSDRVILAGDH
KQLPPTLFSEKNSLEFTLFEKAAERLETSGRVFMLDTQYRMKDEIASFPSMEFYSNRLKSGRPGPEKISNFPKTFPFRDA
LQWIDTAGTDSEEVAVDDSLTNPFEADLQVRLCTLLQENNWPEEEITILSPYRAQVRLLSEKLQEAGLSKIQVSTIDSFQ
GRENRCIFLGFVRSNSEGRSGFLKESRRINVGMTRAKDLLLCIGDSSTLLEDPFLSRFIRFIEEKKFFRTAWEFRDP

Specific function: Unknown

COG id: COG1112

COG function: function code L; Superfamily I DNA and RNA helicases and helicase subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA2/NAM7 helicase family [H]

Homologues:

Organism=Homo sapiens, GI119392094, Length=652, Percent_Identity=33.8957055214724, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI18375673, Length=513, Percent_Identity=28.6549707602339, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI122937299, Length=502, Percent_Identity=25.8964143426295, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI113722133, Length=495, Percent_Identity=27.4747474747475, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI156105695, Length=546, Percent_Identity=26.007326007326, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI156105693, Length=600, Percent_Identity=26.1666666666667, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI254826809, Length=458, Percent_Identity=27.292576419214, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI14251207, Length=498, Percent_Identity=26.7068273092369, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI28626521, Length=285, Percent_Identity=27.719298245614, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI255759908, Length=487, Percent_Identity=26.4887063655031, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI54792138, Length=491, Percent_Identity=24.2362525458248, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI255759910, Length=293, Percent_Identity=29.0102389078498, Blast_Score=93, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17510163, Length=519, Percent_Identity=29.2870905587669, Blast_Score=165, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17533987, Length=464, Percent_Identity=29.3103448275862, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71981659, Length=475, Percent_Identity=28.6315789473684, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17533985, Length=464, Percent_Identity=29.3103448275862, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI133958006, Length=277, Percent_Identity=28.5198555956679, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538027, Length=310, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322835, Length=460, Percent_Identity=33.695652173913, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6321958, Length=475, Percent_Identity=30.3157894736842, Blast_Score=193, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6323726, Length=460, Percent_Identity=31.7391304347826, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323462, Length=530, Percent_Identity=27.5471698113208, Blast_Score=147, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6321024, Length=579, Percent_Identity=27.979274611399, Blast_Score=136, Evalue=8e-33,
Organism=Drosophila melanogaster, GI18859757, Length=489, Percent_Identity=30.2658486707566, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24649577, Length=441, Percent_Identity=28.3446712018141, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI161077698, Length=488, Percent_Identity=26.0245901639344, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24640932, Length=488, Percent_Identity=26.0245901639344, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281363531, Length=463, Percent_Identity=27.645788336933, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281363529, Length=463, Percent_Identity=27.645788336933, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24660647, Length=469, Percent_Identity=24.7334754797441, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221330969, Length=469, Percent_Identity=24.7334754797441, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45553113, Length=495, Percent_Identity=23.6363636363636, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550425, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR004483 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 72768; Mature: 72768

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERKFSSSIEELEFVRAELEREKKEEGFLFSKDWLSRSLQDRIKLGIALYPLVYEEQSF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCEEEEEEECCCCC
GRGGSWILTFRFPNQEEYPSKFQPGALVQIGKNEDRVRAILVSLHKERIRIAIEEVPEWI
CCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDGKCFLDLLPDETSYKEMLYALDAVSSAPKGTRLYVNRELLLGYGKPDPIAIRKSDETR
HCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEECCCHHH
ILQRLNSSLNPSQKNAVLRCVLSEDIAVIHGPPGTGKTTTLTEIISQIVAEEKKVLVSAP
HHHHHCCCCCCCHHHHHEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECC
THSACDLLVESISAKGISVLRLGHPARISDTALHTTLDYKLFHHSDGKLLNEYRRDVIEI
CHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHEEEEEEEEECCCCHHHHHHHHHHHHH
SKQAKKYKRNFGEKEKEDRKNLFQEVKELKKTIRSMEKGLIDSLISSHSVIVSTPVASAR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHH
SVLEGRRFDFCVLDESSQALEPATWIPILKSDRVILAGDHKQLPPTLFSEKNSLEFTLFE
HHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCEEEECCCCCCCCHHHCCCCCCEEHHHH
KAAERLETSGRVFMLDTQYRMKDEIASFPSMEFYSNRLKSGRPGPEKISNFPKTFPFRDA
HHHHHHHCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCHHHH
LQWIDTAGTDSEEVAVDDSLTNPFEADLQVRLCTLLQENNWPEEEITILSPYRAQVRLLS
HHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHEEEECCHHHHHHHHH
EKLQEAGLSKIQVSTIDSFQGRENRCIFLGFVRSNSEGRSGFLKESRRINVGMTRAKDLL
HHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCHHHCCCCEECCCCCCCEEE
LCIGDSSTLLEDPFLSRFIRFIEEKKFFRTAWEFRDP
EEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKERKFSSSIEELEFVRAELEREKKEEGFLFSKDWLSRSLQDRIKLGIALYPLVYEEQSF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCEEEEEEECCCCC
GRGGSWILTFRFPNQEEYPSKFQPGALVQIGKNEDRVRAILVSLHKERIRIAIEEVPEWI
CCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDGKCFLDLLPDETSYKEMLYALDAVSSAPKGTRLYVNRELLLGYGKPDPIAIRKSDETR
HCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEECCCHHH
ILQRLNSSLNPSQKNAVLRCVLSEDIAVIHGPPGTGKTTTLTEIISQIVAEEKKVLVSAP
HHHHHCCCCCCCHHHHHEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECC
THSACDLLVESISAKGISVLRLGHPARISDTALHTTLDYKLFHHSDGKLLNEYRRDVIEI
CHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHEEEEEEEEECCCCHHHHHHHHHHHHH
SKQAKKYKRNFGEKEKEDRKNLFQEVKELKKTIRSMEKGLIDSLISSHSVIVSTPVASAR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHH
SVLEGRRFDFCVLDESSQALEPATWIPILKSDRVILAGDHKQLPPTLFSEKNSLEFTLFE
HHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCEEEECCCCCCCCHHHCCCCCCEEHHHH
KAAERLETSGRVFMLDTQYRMKDEIASFPSMEFYSNRLKSGRPGPEKISNFPKTFPFRDA
HHHHHHHCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCHHHH
LQWIDTAGTDSEEVAVDDSLTNPFEADLQVRLCTLLQENNWPEEEITILSPYRAQVRLLS
HHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHEEEECCHHHHHHHHH
EKLQEAGLSKIQVSTIDSFQGRENRCIFLGFVRSNSEGRSGFLKESRRINVGMTRAKDLL
HHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCHHHCCCCEECCCCCCCEEE
LCIGDSSTLLEDPFLSRFIRFIEEKKFFRTAWEFRDP
EEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]