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The map label for this gene is tig

Identifier: 116327861

GI number: 116327861

Start: 1345171

End: 1346526

Strand: Direct

Name: tig

Synonym: LBL_1140

Alternate gene names: 116327861

Gene position: 1345171-1346526 (Clockwise)

Preceding gene: 116327860

Following gene: 116327862

Centisome position: 37.22

GC content: 38.57

Gene sequence:

>1356_bases
ATGGATTATAAAACAAAAAAAAATTCCAACGCTACCGTTGATATCAAACTTACTTTTGAAGCTTCCGATTTAGAGAAAGC
CTTTGATAAGACGTATGCAGAAAAACAAAAAAACATAAAGATTCCGGGCTTCCGTCCGGGAAAGGCGCCGCTGAATATGG
TGAAGCGTCATCTCGGCGATACAGTGGCTAGTGATGCTATTAACACCTTGATCGTGGATGGAATGGCTTCCATTCTTACA
AAATTAGAACATCCGATGGTTCGGTTTCCGAAATTTGAAATCCAAGACTACCAACCCGGTAAGAATCTGATTGCGACTGC
GGTTTACGAAACTAATCCGGAGATCACTCTCGGAAAATACAAAAAAATAAAAGTTAAACTTCCGGAAGTTTCCGTTTCCG
ACTCCGATATTTTCGACGAAATTGAAAATATTCGTAAACAACTCGCTCGCAAGCAGTTGAAGGAAGATGGGCAAACCGCC
GCTTCCGGAGATATTATCGATATGGAATATACTGTTTGTGAAAAAGGCCAGGAACCGAAAAACGCAAGCAATACTTCCAA
CGACTATCACTTGGGTCATGAAAACAATTTAAAAGGTTTCGATGAAAACCTCTATGGACTAGGGGTCGGTGATAGAAAAG
AATTTTCCCATACCTTTCCGGAAGATTATCTTCAGAACGAGGTTGCGGGGAAGACCTTTGAATATTCTGTAACAATCAAG
GCGCTGTATGTCAATATTCTTCCCACGGTGGACGATGATTTGGCTGCCGAGTTTGATGGTTCCGATTCCTTAAACACTTT
GAAAGACAAGATTCGTAAAAATCTCAAGGAACGTTTTGAAGAAGGAATCCGAAATAAGAAGTTGGAAGAAATTTTTAAGG
AGATCATAGACGATTCGAAATATATTTTTCCGGATTCTTATGTTAAGGAGGAATCGGAACACGTTTTTCACAATATGATT
CACGAATTTAAACTTCCACATATTACGATGGAAAAATATGCCAAGATGATCAAAAAGGATCTGAAAGAAGTTCAGGAATC
TTTTAGGAATTTGGCAGAAAACCGTCTTAAACATTTCTTTACCCGTCAAAAAATTGCCGAGATCGAAAATGTTACGTATA
CCGAGACGGATTTTGATGCGGATTTGGAAAAACTTGCGTCAAGTTATCAAATTCCCTTGTCCGATCTTAAAGAAGAGTTG
GAAAAGGGAAAACTCATGGATCAATATCGGGAGAATTTTTTCGCAAAAAAGGTGGATCATACCCTCTTTGATCTTGTAGA
AAAGAAATACACTAACAAATTGAGTATTGGACAGGTAAAAGACTACCTGAATCAAAAGGAAGAACAGAAAGTATGA

Upstream 100 bases:

>100_bases
CAGTGGTAGAGCACCTCCTTGCCAAGGAGGGGGTCGCGGGTTCGAGCCCCGTTTCCCGCTTTTTCTTTTATATCATCTCT
TCTCCAGGCCGATTTGCATC

Downstream 100 bases:

>100_bases
GTGTAATTCCGTATGTGATCGAGCAGACGAGTCGAGGGGAGAGGTCTTACGATATATTTTCCCGGCTTTTAAAAGACAGA
ATTATTTTTCTCGGGAATGC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MDYKTKKNSNATVDIKLTFEASDLEKAFDKTYAEKQKNIKIPGFRPGKAPLNMVKRHLGDTVASDAINTLIVDGMASILT
KLEHPMVRFPKFEIQDYQPGKNLIATAVYETNPEITLGKYKKIKVKLPEVSVSDSDIFDEIENIRKQLARKQLKEDGQTA
ASGDIIDMEYTVCEKGQEPKNASNTSNDYHLGHENNLKGFDENLYGLGVGDRKEFSHTFPEDYLQNEVAGKTFEYSVTIK
ALYVNILPTVDDDLAAEFDGSDSLNTLKDKIRKNLKERFEEGIRNKKLEEIFKEIIDDSKYIFPDSYVKEESEHVFHNMI
HEFKLPHITMEKYAKMIKKDLKEVQESFRNLAENRLKHFFTRQKIAEIENVTYTETDFDADLEKLASSYQIPLSDLKEEL
EKGKLMDQYRENFFAKKVDHTLFDLVEKKYTNKLSIGQVKDYLNQKEEQKV

Sequences:

>Translated_451_residues
MDYKTKKNSNATVDIKLTFEASDLEKAFDKTYAEKQKNIKIPGFRPGKAPLNMVKRHLGDTVASDAINTLIVDGMASILT
KLEHPMVRFPKFEIQDYQPGKNLIATAVYETNPEITLGKYKKIKVKLPEVSVSDSDIFDEIENIRKQLARKQLKEDGQTA
ASGDIIDMEYTVCEKGQEPKNASNTSNDYHLGHENNLKGFDENLYGLGVGDRKEFSHTFPEDYLQNEVAGKTFEYSVTIK
ALYVNILPTVDDDLAAEFDGSDSLNTLKDKIRKNLKERFEEGIRNKKLEEIFKEIIDDSKYIFPDSYVKEESEHVFHNMI
HEFKLPHITMEKYAKMIKKDLKEVQESFRNLAENRLKHFFTRQKIAEIENVTYTETDFDADLEKLASSYQIPLSDLKEEL
EKGKLMDQYRENFFAKKVDHTLFDLVEKKYTNKLSIGQVKDYLNQKEEQKV
>Mature_451_residues
MDYKTKKNSNATVDIKLTFEASDLEKAFDKTYAEKQKNIKIPGFRPGKAPLNMVKRHLGDTVASDAINTLIVDGMASILT
KLEHPMVRFPKFEIQDYQPGKNLIATAVYETNPEITLGKYKKIKVKLPEVSVSDSDIFDEIENIRKQLARKQLKEDGQTA
ASGDIIDMEYTVCEKGQEPKNASNTSNDYHLGHENNLKGFDENLYGLGVGDRKEFSHTFPEDYLQNEVAGKTFEYSVTIK
ALYVNILPTVDDDLAAEFDGSDSLNTLKDKIRKNLKERFEEGIRNKKLEEIFKEIIDDSKYIFPDSYVKEESEHVFHNMI
HEFKLPHITMEKYAKMIKKDLKEVQESFRNLAENRLKHFFTRQKIAEIENVTYTETDFDADLEKLASSYQIPLSDLKEEL
EKGKLMDQYRENFFAKKVDHTLFDLVEKKYTNKLSIGQVKDYLNQKEEQKV

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=397, Percent_Identity=22.4181360201511, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_LEPBJ (Q04TR5)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800463.1
- ProteinModelPortal:   Q04TR5
- STRING:   Q04TR5
- GeneID:   4411827
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1083
- eggNOG:   COG0544
- HOGENOM:   HBG531038
- OMA:   RFIPGFE
- ProtClustDB:   CLSK574478
- BioCyc:   LBOR355277:LBJ_1083-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 52172; Mature: 52172

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKTKKNSNATVDIKLTFEASDLEKAFDKTYAEKQKNIKIPGFRPGKAPLNMVKRHLGD
CCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TVASDAINTLIVDGMASILTKLEHPMVRFPKFEIQDYQPGKNLIATAVYETNPEITLGKY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEECCC
KKIKVKLPEVSVSDSDIFDEIENIRKQLARKQLKEDGQTAASGDIIDMEYTVCEKGQEPK
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCCC
NASNTSNDYHLGHENNLKGFDENLYGLGVGDRKEFSHTFPEDYLQNEVAGKTFEYSVTIK
CCCCCCCCEECCCCCCCCCCCCCCEECCCCCHHHHCCCCCHHHHHHHHCCCEEEEEEEEE
ALYVNILPTVDDDLAAEFDGSDSLNTLKDKIRKNLKERFEEGIRNKKLEEIFKEIIDDSK
EEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
YIFPDSYVKEESEHVFHNMIHEFKLPHITMEKYAKMIKKDLKEVQESFRNLAENRLKHFF
EECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRQKIAEIENVTYTETDFDADLEKLASSYQIPLSDLKEELEKGKLMDQYRENFFAKKVDH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFDLVEKKYTNKLSIGQVKDYLNQKEEQKV
HHHHHHHHHHCCCCCHHHHHHHHCHHHHCCC
>Mature Secondary Structure
MDYKTKKNSNATVDIKLTFEASDLEKAFDKTYAEKQKNIKIPGFRPGKAPLNMVKRHLGD
CCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TVASDAINTLIVDGMASILTKLEHPMVRFPKFEIQDYQPGKNLIATAVYETNPEITLGKY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEECCC
KKIKVKLPEVSVSDSDIFDEIENIRKQLARKQLKEDGQTAASGDIIDMEYTVCEKGQEPK
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCCC
NASNTSNDYHLGHENNLKGFDENLYGLGVGDRKEFSHTFPEDYLQNEVAGKTFEYSVTIK
CCCCCCCCEECCCCCCCCCCCCCCEECCCCCHHHHCCCCCHHHHHHHHCCCEEEEEEEEE
ALYVNILPTVDDDLAAEFDGSDSLNTLKDKIRKNLKERFEEGIRNKKLEEIFKEIIDDSK
EEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
YIFPDSYVKEESEHVFHNMIHEFKLPHITMEKYAKMIKKDLKEVQESFRNLAENRLKHFF
EECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRQKIAEIENVTYTETDFDADLEKLASSYQIPLSDLKEELEKGKLMDQYRENFFAKKVDH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFDLVEKKYTNKLSIGQVKDYLNQKEEQKV
HHHHHHHHHHCCCCCHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA