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The map label for this gene is yaeL [C]

Identifier: 116327680

GI number: 116327680

Start: 1068175

End: 1069902

Strand: Direct

Name: yaeL [C]

Synonym: LBL_0926

Alternate gene names: 116327680

Gene position: 1068175-1069902 (Clockwise)

Preceding gene: 116327679

Following gene: 116327681

Centisome position: 29.55

GC content: 44.21

Gene sequence:

>1728_bases
ATGTTAATCATGATATTAGGCGCAGTGTTTATGCTGGCTATTTCTATTTTTATTCACGAGTTGGGTCATCTTCTTTGTGG
AATGCTCGTAGGAGTTAAGGCTAGAATTTTTTCGATCGGTTACGGAAGAGGGATCTGGAAGAAAAAAGTGGGAGATACCA
CGTATCAGATCACCGCGATTCCCGTCGGAGGATACGTTTTATTTAAAGGAGACGACTACGACGGAGAAGTGAAAGGGGAA
CCCGGTGAACTTCTTTCCACTCCTCCTTTGAAGAGAATGATTCCGGTGCTCGGAGGTCCTCTTTTTAACTTATTTTTGGG
ATTTGGAATATTATTAATTTTGAATTTTCTAGGTCACAATCCTCCGGGAAACCGGATTTTTATCGATCCGGCCGATCAGG
AATTTTCCGCCGCATACCAATCGGGTCTCAGAACGGGGGATCGTATCCTAAATATAGACGGAAACAAAATCGAAAAATTT
GAAGACATAGTGACTAACGTAGGATTGTCTTCCGGAAACTCTCTCAAAATTTTGGGTGAGCGCGAAGGGCAAAAGATGGA
ATGGAAAGTGATTCCCAGGATCGTTTATAATCCGAAACGCTCTTCCGGGATTCCGACTATTGGCGTGGAACCCTTCGGAG
AAAGAAGGGTCGTTGCGACGTTCGGCTATCCGGAACAGTTTCAACATTGGTTATCTTCTCGTTTGGATAGATCTCACGAA
GCGGAAAATTACTATCAGGAACGTTTGAAAAAGGCTGTCGAGGGAAGGGGTATCCCCGCCGAAGTTCTGCTCGAAAAGGA
AAGAGAGGAGAAGGAAAATCTGCTTCGCTCCAGAGCGTTGAATTATCTGAACGACGGAGACGTGATTCAGACCGTGAACG
GCAAGGCAGTTTCTACCGTGGGGGAACTTCAAAAAATTCTTGGGGAATATCAAGGCCGAACCGTGACGATTGTTGTAGAT
CGAAAAACATATCCTCTCGTAAATCCTTGGTCCACAGAAATTGTTTCCGTGGGAATTCCCGTTTTAGGGGCTAATATATT
AGAATTTGGGAATATTCGGGATCAGAAATTTCCTGAGTTGAATTTGGAATCCTACCAGTTTGCGAGTTACGATCCCGAAC
TCGGCCAGAAACTTCTCAATCTGGCAGTGGACGGAAAAATGTTTCCTAGTTTTGAAGAACTTCTCGCTTATATTAAAACG
AAGAACGGAAAAACCGTTACGGTCGATATGGGAAATCTTAAATTGGAAGCCGAGCCGAAAGTTCGTCCAATCGGGCTTCT
CGGGTTTAGGCCCAATATGAAATTCAATCCGGAACCGATGCAGAGGGAACTCGGTTTTTTGGAATCTTTCATCGTCGCCG
GAAAAGACGTTTATGAAAATGTGGAAATCACTCTTAAAGGAATCGGGATGTTGTTTTCAGGGATTCTTTCCGTAAAGGAT
AGTCTTTCCGGGCCTGTGGGAATCGTGTCGTATGCGGGAATCAGCTTGGAAATCGGTTGGGAGACGTATTTGGAATTCGT
TGCTAGGATCTCGATCGCTTTGATGATTATGAATTTACTTCCCATTCCCATGGCGGACGGTGGGCATATCGTATTATATG
CGTATGAAGCGATTACCGGAAGACCTCTTCCCGGTAGAGTAATCGAGTCCATCTTCCGAATCGGATTTTTGTTTTTACTC
GGACTCGGACTCTATGTCACTTTCAACGATGTAATGCGAATTTTCTAA

Upstream 100 bases:

>100_bases
TGCCGATCGATTTTCCGACTTCTTTGGAAGAATACGAGGAAGTCGATCGGATCGCCCGTAAAACCGTCCTAAATCTGAAA
GCAAGGAAGGTGGTGTCCGC

Downstream 100 bases:

>100_bases
ACGCATGAAAGCATCGAAATATATTCTTCCTACAGAAAAGGAAAATCCCTCGGATGCGGTCGTCGCGTCCCATCGTCTTA
TGATCCGCGCCGGTCTTGCG

Product: Zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MLIMILGAVFMLAISIFIHELGHLLCGMLVGVKARIFSIGYGRGIWKKKVGDTTYQITAIPVGGYVLFKGDDYDGEVKGE
PGELLSTPPLKRMIPVLGGPLFNLFLGFGILLILNFLGHNPPGNRIFIDPADQEFSAAYQSGLRTGDRILNIDGNKIEKF
EDIVTNVGLSSGNSLKILGEREGQKMEWKVIPRIVYNPKRSSGIPTIGVEPFGERRVVATFGYPEQFQHWLSSRLDRSHE
AENYYQERLKKAVEGRGIPAEVLLEKEREEKENLLRSRALNYLNDGDVIQTVNGKAVSTVGELQKILGEYQGRTVTIVVD
RKTYPLVNPWSTEIVSVGIPVLGANILEFGNIRDQKFPELNLESYQFASYDPELGQKLLNLAVDGKMFPSFEELLAYIKT
KNGKTVTVDMGNLKLEAEPKVRPIGLLGFRPNMKFNPEPMQRELGFLESFIVAGKDVYENVEITLKGIGMLFSGILSVKD
SLSGPVGIVSYAGISLEIGWETYLEFVARISIALMIMNLLPIPMADGGHIVLYAYEAITGRPLPGRVIESIFRIGFLFLL
GLGLYVTFNDVMRIF

Sequences:

>Translated_575_residues
MLIMILGAVFMLAISIFIHELGHLLCGMLVGVKARIFSIGYGRGIWKKKVGDTTYQITAIPVGGYVLFKGDDYDGEVKGE
PGELLSTPPLKRMIPVLGGPLFNLFLGFGILLILNFLGHNPPGNRIFIDPADQEFSAAYQSGLRTGDRILNIDGNKIEKF
EDIVTNVGLSSGNSLKILGEREGQKMEWKVIPRIVYNPKRSSGIPTIGVEPFGERRVVATFGYPEQFQHWLSSRLDRSHE
AENYYQERLKKAVEGRGIPAEVLLEKEREEKENLLRSRALNYLNDGDVIQTVNGKAVSTVGELQKILGEYQGRTVTIVVD
RKTYPLVNPWSTEIVSVGIPVLGANILEFGNIRDQKFPELNLESYQFASYDPELGQKLLNLAVDGKMFPSFEELLAYIKT
KNGKTVTVDMGNLKLEAEPKVRPIGLLGFRPNMKFNPEPMQRELGFLESFIVAGKDVYENVEITLKGIGMLFSGILSVKD
SLSGPVGIVSYAGISLEIGWETYLEFVARISIALMIMNLLPIPMADGGHIVLYAYEAITGRPLPGRVIESIFRIGFLFLL
GLGLYVTFNDVMRIF
>Mature_575_residues
MLIMILGAVFMLAISIFIHELGHLLCGMLVGVKARIFSIGYGRGIWKKKVGDTTYQITAIPVGGYVLFKGDDYDGEVKGE
PGELLSTPPLKRMIPVLGGPLFNLFLGFGILLILNFLGHNPPGNRIFIDPADQEFSAAYQSGLRTGDRILNIDGNKIEKF
EDIVTNVGLSSGNSLKILGEREGQKMEWKVIPRIVYNPKRSSGIPTIGVEPFGERRVVATFGYPEQFQHWLSSRLDRSHE
AENYYQERLKKAVEGRGIPAEVLLEKEREEKENLLRSRALNYLNDGDVIQTVNGKAVSTVGELQKILGEYQGRTVTIVVD
RKTYPLVNPWSTEIVSVGIPVLGANILEFGNIRDQKFPELNLESYQFASYDPELGQKLLNLAVDGKMFPSFEELLAYIKT
KNGKTVTVDMGNLKLEAEPKVRPIGLLGFRPNMKFNPEPMQRELGFLESFIVAGKDVYENVEITLKGIGMLFSGILSVKD
SLSGPVGIVSYAGISLEIGWETYLEFVARISIALMIMNLLPIPMADGGHIVLYAYEAITGRPLPGRVIESIFRIGFLFLL
GLGLYVTFNDVMRIF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M50B family [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=203, Percent_Identity=30.5418719211823, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 63934; Mature: 63934

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIMILGAVFMLAISIFIHELGHLLCGMLVGVKARIFSIGYGRGIWKKKVGDTTYQITAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHCCCCCEEEEEEE
PVGGYVLFKGDDYDGEVKGEPGELLSTPPLKRMIPVLGGPLFNLFLGFGILLILNFLGHN
EECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
PPGNRIFIDPADQEFSAAYQSGLRTGDRILNIDGNKIEKFEDIVTNVGLSSGNSLKILGE
CCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEC
REGQKMEWKVIPRIVYNPKRSSGIPTIGVEPFGERRVVATFGYPEQFQHWLSSRLDRSHE
CCCCEEEEEEECHHEECCCCCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
AENYYQERLKKAVEGRGIPAEVLLEKEREEKENLLRSRALNYLNDGDVIQTVNGKAVSTV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHH
GELQKILGEYQGRTVTIVVDRKTYPLVNPWSTEIVSVGIPVLGANILEFGNIRDQKFPEL
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHEECCCHHHHHHHHHCCCCCCCCCCC
NLESYQFASYDPELGQKLLNLAVDGKMFPSFEELLAYIKTKNGKTVTVDMGNLKLEAEPK
CCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCEEEECCCC
VRPIGLLGFRPNMKFNPEPMQRELGFLESFIVAGKDVYENVEITLKGIGMLFSGILSVKD
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHHHHHHH
SLSGPVGIVSYAGISLEIGWETYLEFVARISIALMIMNLLPIPMADGGHIVLYAYEAITG
HCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCC
RPLPGRVIESIFRIGFLFLLGLGLYVTFNDVMRIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIMILGAVFMLAISIFIHELGHLLCGMLVGVKARIFSIGYGRGIWKKKVGDTTYQITAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHCCCCCEEEEEEE
PVGGYVLFKGDDYDGEVKGEPGELLSTPPLKRMIPVLGGPLFNLFLGFGILLILNFLGHN
EECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
PPGNRIFIDPADQEFSAAYQSGLRTGDRILNIDGNKIEKFEDIVTNVGLSSGNSLKILGE
CCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEC
REGQKMEWKVIPRIVYNPKRSSGIPTIGVEPFGERRVVATFGYPEQFQHWLSSRLDRSHE
CCCCEEEEEEECHHEECCCCCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
AENYYQERLKKAVEGRGIPAEVLLEKEREEKENLLRSRALNYLNDGDVIQTVNGKAVSTV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHH
GELQKILGEYQGRTVTIVVDRKTYPLVNPWSTEIVSVGIPVLGANILEFGNIRDQKFPEL
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHEECCCHHHHHHHHHCCCCCCCCCCC
NLESYQFASYDPELGQKLLNLAVDGKMFPSFEELLAYIKTKNGKTVTVDMGNLKLEAEPK
CCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCEEEECCCC
VRPIGLLGFRPNMKFNPEPMQRELGFLESFIVAGKDVYENVEITLKGIGMLFSGILSVKD
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHHHHHHH
SLSGPVGIVSYAGISLEIGWETYLEFVARISIALMIMNLLPIPMADGGHIVLYAYEAITG
HCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCC
RPLPGRVIESIFRIGFLFLLGLGLYVTFNDVMRIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]