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The map label for this gene is ybdL [H]

Identifier: 115352314

GI number: 115352314

Start: 2500184

End: 2501356

Strand: Direct

Name: ybdL [H]

Synonym: Bamb_2263

Alternate gene names: 115352314

Gene position: 2500184-2501356 (Clockwise)

Preceding gene: 115352313

Following gene: 115352316

Centisome position: 70.3

GC content: 65.9

Gene sequence:

>1173_bases
ATGAACGCTCCTTCCGACATGCCTACGAATCCCGTTTTCCCATCGCGCCTGCCGACCGTCGGCACCACGATCTTCACGGT
CATGAGCGCGCTCGCCGCCGAGAAAGGCGCCGTGAATCTCGGCCAGGGCTTCCCGGATTTCGACTGTGACCCGCGCATCG
TCGACGCGGTCGCGGCCGCGATGCGCAACGGCCACAACCAGTATCCGCCGATGGCGGGCGTCGCCCCGCTGCGCGACGCG
ATCGCCGACAAGATCGCGCAGGTCTACGGCCGGCGCTACGACCCGGCCACCGAGATCACGGTGACGGCCGGCGCGACGCA
GGCACTGCTGACGGCGATCCTGTGCGCGGTGCATCCGGGCGACGAGGTGATCGTCGTCGAGCCGACCTACGACAGCTACC
TGCCGTCGATCGAGCTCGCCGGCGGCAAGCCGGTGTTCGTCACGCTGGAGGCGCCCGACTATGCGATCCCGTTCGATCGT
CTCGCCGCCGCGATCACGCCGAAGACGCGGATGATCATGATCAACACGCCGCACAATCCGACCGGCACCGTGTGGCGCGA
GGCCGACATGCGCAAGCTCGAGGAGATCGTGCGCGGCACCAACGTGCTGACCCTGTCCGATGAAGTGTATGAGCACATGG
TCTACGACGGCGCCCGGCACGAGAGCGTCGCGCGCTACCCGGAATTGGCCGAGCGCAGTTTCATCGTGTCGAGCTTCGGG
AAGACTTACCACGTGACGGGCTGGAAGATCGGCTATGTCGCGGCGCCTGCCGCACTGATGGCCGAATTCCGCAAGGTCCA
TCAGTTCAACGTGTTCACGGTGAACACGCCGACGCAGATCGGGCTCGCCGACTACCTGCGCGACCCGGCACCGTACCTGA
CGCTGCCCGACTTCTACCAGAAGAAGCGCGACTTCTTCCGCGCCGGCCTCGAACGCACGCGCTTCAAGCTGCTGCCGTGC
ACGGGCACGTACTTCCAGTGCGTCGACTATTCGGCGATCAGCGACCTGCCCGAAGCGGAATTCTCGAAGTGGCTCACGTC
GGAGATCGGCGTGGCGGCGATTCCGGTGTCGGCGTTCTATCACGAGCCGCACGAATCGGGCGTCGTGCGCTTCTGCTTCG
CGAAACAGGAAAGCACGCTCGCGTCCGCACTCGAGCGGCTCGCGCGCCTGTAA

Upstream 100 bases:

>100_bases
CAGCCCGCGCCGTTTACCGAAGCCTGCGCGCTCGATGCCGCGTCGGCCATCCCCACCACGCCGGCCTGACGGGCCGACGC
AACACGCTGCGACCGTATCG

Downstream 100 bases:

>100_bases
GTCCGGCACGGGCAGCAAGGCGCTGCCCGCTCTGTATCCGGCTAGTGCTTACGAACGCGCGGCGGCTGTCGCCTCGACAT
AGGCCTTGCGATCGGCCGCC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNAPSDMPTNPVFPSRLPTVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPATEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMIMINTPHNPTGTVWREADMRKLEEIVRGTNVLTLSDEVYEHMVYDGARHESVARYPELAERSFIVSSFG
KTYHVTGWKIGYVAAPAALMAEFRKVHQFNVFTVNTPTQIGLADYLRDPAPYLTLPDFYQKKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL

Sequences:

>Translated_390_residues
MNAPSDMPTNPVFPSRLPTVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPATEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMIMINTPHNPTGTVWREADMRKLEEIVRGTNVLTLSDEVYEHMVYDGARHESVARYPELAERSFIVSSFG
KTYHVTGWKIGYVAAPAALMAEFRKVHQFNVFTVNTPTQIGLADYLRDPAPYLTLPDFYQKKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL
>Mature_390_residues
MNAPSDMPTNPVFPSRLPTVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPATEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMIMINTPHNPTGTVWREADMRKLEEIVRGTNVLTLSDEVYEHMVYDGARHESVARYPELAERSFIVSSFG
KTYHVTGWKIGYVAAPAALMAEFRKVHQFNVFTVNTPTQIGLADYLRDPAPYLTLPDFYQKKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=34.9633251833741, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=34.9633251833741, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=33.9152119700748, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=33.9152119700748, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=30.6372549019608, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4507369, Length=216, Percent_Identity=26.8518518518519, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=51.5544041450777, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1788722, Length=377, Percent_Identity=24.6684350132626, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788627, Length=188, Percent_Identity=31.9148936170213, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787710, Length=297, Percent_Identity=28.2828282828283, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=36.1386138613861, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=36.1386138613861, Blast_Score=234, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=32.0802005012531, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=33.3333333333333, Blast_Score=193, Evalue=4e-50,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=36.0097323600973, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=36.0097323600973, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=36.0097323600973, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=36.0097323600973, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI18859735, Length=217, Percent_Identity=27.1889400921659, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43010; Mature: 43010

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPSDMPTNPVFPSRLPTVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
MRNGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPATEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMIMINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTVWREADMRKLEEIVRGTNVLTLSDEVYEHMVYDGARHESVARYPELAERSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKIGYVAAPAALMAEFRKVHQFNVFTVNTPTQIGLADYLRDPAPYLTLPDFYQ
CEEEECCEEEHHHHCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHCCCCCCCCCCHHHH
KKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFY
HHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHHCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLASALERLARL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPSDMPTNPVFPSRLPTVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
MRNGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPATEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMIMINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTVWREADMRKLEEIVRGTNVLTLSDEVYEHMVYDGARHESVARYPELAERSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKIGYVAAPAALMAEFRKVHQFNVFTVNTPTQIGLADYLRDPAPYLTLPDFYQ
CEEEECCEEEHHHHCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHCCCCCCCCCCHHHH
KKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFY
HHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHHCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLASALERLARL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]