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The map label for this gene is paaF [H]

Identifier: 115352316

GI number: 115352316

Start: 2502273

End: 2503064

Strand: Direct

Name: paaF [H]

Synonym: Bamb_2265

Alternate gene names: 115352316

Gene position: 2502273-2503064 (Clockwise)

Preceding gene: 115352314

Following gene: 115352317

Centisome position: 70.36

GC content: 68.81

Gene sequence:

>792_bases
ATGAGTGCTGAACTGCTGGCCTCGCGTCCGCCCGAGAGCGAATCGACGCTCGTCCTCACGCTGTCCAATCCCGGCGCGCG
CAATGCGCTGCATCCCGACATGTATGCGGCCGGCGTCGAAGCGCTCGCCACCGCCGAGCGTGATCCCGCGATTCGCGCGG
TCGTGCTCACGGGCGCCGATCGTTTCTTTTGCGCGGGCGGCAACCTGAACCGGCTGCTCGAGAACCGCTCGAAGGATCCG
TCCTACCAGGCCGACGGCATCGATCAGCTCGGCGCGTGGATCACGGCGATCCGCGCATCGACGAAACCCGTGATCGCGGC
GGTCGAAGGTGCGGCGGCCGGCGCGGGCTTCTCGCTCGCGCTCGCGTGCGACCTGATCGTCGCCGCACACGACGCGAAGT
TCGTGATGTCGTATGCGCGCGTCGGCCTCACGCCCGACGGCGGCGGCTCGTGGTTCCTCGCCCGCGCGCTGCCGCGTGCG
CTGGCCGCCGAAATCCTGTTCGAAGGCAAGCCCGTCGCGGCCGAACGCCTGCACGCGCTCGGCGTCGTCAATCGGCTCGC
CGTGCCCGGCGCCGCATTGTCCGATGCGCTCGCGTGGGCCGATTCGCTTGCCGGCATCTCGCCGAACGCACTCACGCGCA
TCAAGTCGCTGCTCGACGATGCGCCCGCACAGCCGCTCGAAACCCATCTCGGCACCGAGCGCGATCACTTCGTCGCGTCG
CTGCATCATGCGGACGCGTTCGAAGGCATTACCGCGTTTCTCGAGAAACGCCAGCCGCGCTACAAGCGCTGA

Upstream 100 bases:

>100_bases
ACAACAATGCATCCGCTGCGGCAGCGCCCTCGCGGGTATGCGCACGAGCCCGCGCAACGCGCGGCGCCGCAGCCTCGCCA
TCCGATGGAGACACCCTCGC

Downstream 100 bases:

>100_bases
TCCGCGCAATCCCGCTGTTCTAACGGCCTCGCCGCGCCGCATCGACACGCCGTGCGCCGGCGCGCGGCCGCGCCTTCCCG
CCGCCTGCAGCGCACGTCGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSAELLASRPPESESTLVLTLSNPGARNALHPDMYAAGVEALATAERDPAIRAVVLTGADRFFCAGGNLNRLLENRSKDP
SYQADGIDQLGAWITAIRASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRA
LAAEILFEGKPVAAERLHALGVVNRLAVPGAALSDALAWADSLAGISPNALTRIKSLLDDAPAQPLETHLGTERDHFVAS
LHHADAFEGITAFLEKRQPRYKR

Sequences:

>Translated_263_residues
MSAELLASRPPESESTLVLTLSNPGARNALHPDMYAAGVEALATAERDPAIRAVVLTGADRFFCAGGNLNRLLENRSKDP
SYQADGIDQLGAWITAIRASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRA
LAAEILFEGKPVAAERLHALGVVNRLAVPGAALSDALAWADSLAGISPNALTRIKSLLDDAPAQPLETHLGTERDHFVAS
LHHADAFEGITAFLEKRQPRYKR
>Mature_262_residues
SAELLASRPPESESTLVLTLSNPGARNALHPDMYAAGVEALATAERDPAIRAVVLTGADRFFCAGGNLNRLLENRSKDPS
YQADGIDQLGAWITAIRASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRAL
AAEILFEGKPVAAERLHALGVVNRLAVPGAALSDALAWADSLAGISPNALTRIKSLLDDAPAQPLETHLGTERDHFVASL
HHADAFEGITAFLEKRQPRYKR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=260, Percent_Identity=30.7692307692308, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI31542718, Length=244, Percent_Identity=30.7377049180328, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=28.8973384030418, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI221136756, Length=246, Percent_Identity=24.7967479674797, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI221136753, Length=246, Percent_Identity=24.7967479674797, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI221307494, Length=207, Percent_Identity=27.0531400966184, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI70995211, Length=180, Percent_Identity=31.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI25453481, Length=204, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538573, Length=204, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757966, Length=204, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538581, Length=204, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI116235487, Length=207, Percent_Identity=28.5024154589372, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4757968, Length=206, Percent_Identity=26.6990291262136, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI49355787, Length=206, Percent_Identity=26.6990291262136, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI260274832, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI45643119, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI260275230, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=25.5681818181818, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=36.7816091954023, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=35.1778656126482, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787660, Length=254, Percent_Identity=36.6141732283465, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=32.5396825396825, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082183, Length=243, Percent_Identity=28.8065843621399, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788682, Length=184, Percent_Identity=31.5217391304348, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=31.1023622047244, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=31.1023622047244, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=177, Percent_Identity=30.5084745762712, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=257, Percent_Identity=26.8482490272374, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=245, Percent_Identity=24.8979591836735, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=22.568093385214, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=167, Percent_Identity=30.5389221556886, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=169, Percent_Identity=26.6272189349112, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=243, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=251, Percent_Identity=31.0756972111554, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653477, Length=251, Percent_Identity=31.0756972111554, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653139, Length=250, Percent_Identity=32, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922422, Length=245, Percent_Identity=29.7959183673469, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24654903, Length=243, Percent_Identity=23.4567901234568, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920382, Length=209, Percent_Identity=29.6650717703349, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357171, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27650; Mature: 27518

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAELLASRPPESESTLVLTLSNPGARNALHPDMYAAGVEALATAERDPAIRAVVLTGAD
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCC
RFFCAGGNLNRLLENRSKDPSYQADGIDQLGAWITAIRASTKPVIAAVEGAAAGAGFSLA
EEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRALAAEILFEGKPVAAERLHAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVVNRLAVPGAALSDALAWADSLAGISPNALTRIKSLLDDAPAQPLETHLGTERDHFVAS
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
LHHADAFEGITAFLEKRQPRYKR
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAELLASRPPESESTLVLTLSNPGARNALHPDMYAAGVEALATAERDPAIRAVVLTGAD
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCC
RFFCAGGNLNRLLENRSKDPSYQADGIDQLGAWITAIRASTKPVIAAVEGAAAGAGFSLA
EEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRALAAEILFEGKPVAAERLHAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVVNRLAVPGAALSDALAWADSLAGISPNALTRIKSLLDDAPAQPLETHLGTERDHFVAS
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
LHHADAFEGITAFLEKRQPRYKR
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]