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The map label for this gene is kgtP [H]

Identifier: 115351566

GI number: 115351566

Start: 1659911

End: 1661215

Strand: Direct

Name: kgtP [H]

Synonym: Bamb_1513

Alternate gene names: 115351566

Gene position: 1659911-1661215 (Clockwise)

Preceding gene: 115351565

Following gene: 115351567

Centisome position: 46.67

GC content: 65.75

Gene sequence:

>1305_bases
ATGGACGTCCAGACCGACCAAGCTGCGCTGTCCGCGCATGACACCCGGCGGCGCGTGTTCGCCATCGTCGGCGCCTCATC
GGGCAACCTCGTCGAGTGGTTCGACTTCTACATTTACTCGTTCTGCGCGCTGTACTTCGCGCCGGCGTTCTTCCCGAGCG
GCAACTCGACGACGCAGTTGCTGAACACGGCCGGCGTGTTCGCGGCCGGTTTCCTGATGCGTCCGATCGGCGGCTGGCTG
TTCGGCCGCATCGCCGACCGTCACGGCCGCCGCGCGGCGATGATGATCTCGGTGCTGATGATGTGCGGCGGCTCGCTCGT
GATCGCGGTCCTGCCGACCTATGCGCAGATCGGCGCGCTCGCGCCGGCGCTGCTGCTGGTCGCGCGTCTGTTCCAGGGGC
TGTCGGTGGGCGGCGAATACGGGACGAGCGCGACCTACATGAGCGAGGTCGCGCTGAAGGGGCGGCGCGGCTTCTTCGCG
TCGTTCCAGTACGTGACGCTGATCGGCGGCCAGCTGTGTGCGCTGCTGGTGCTCGTGATCCTGCAGCAGACGCTGTCGAC
TGACGAACTGAAGGCGTGGGGCTGGCGCATTCCGTTCGTCTGCGGCGCGGCGGCCGCGCTGATCTCGCTGTACCTGCGCA
AATCGCTCGACGAGACGTCGACGAGCGCATCGCGCGACAAGAAGGACGCGGGCACGATCCGCGGCGTGTGGCAGCACAAG
GGCGCATTCTTCACGGTGGTCGGCTTCACGGCCGGCGGCTCGCTGATCTTCTATACGTTCACGACGTACATGCAGAAGTA
CTTGGTGAACACGGCCGGCATGCATGCGAAGACGGCCAGCAACGTGATGACCGTCGCGCTCCTCGTCTACATGCTGATAC
AGCCGGTGTTCGGCGCGCTGTCCGACAAGATCGGCCGCCGCACGTCGATGATCCTGTTCGGCACGTTCGCGGTGATCGGC
ACGGTGCCGCTGATGCACACGCTGAAGACCGTGACGAGCCCGATGGCCGCGTTCGTGCTGATCACGATCGCGCTGGCGAT
CGTCAGCTTCTACACGTCGATCAGCGGCCTCATCAAGGCCGAGATGTTCCCGCCCGAAGTGCGCGCGATGGGCGTCGGCC
TGTCGTATGCGGTCGCGAACGCGATCTTCGGCGGCTCGGCCGAATACGTCGCGCTGTGGTTCAAGTCGGTCGGCAGCGAG
GAAACCTTCTACTGGTACGTGACGGCGCTGTGCGCGGTGTCGCTGATCGTGTCGTGGCGGATGCGCGACCCGAGCAAGGA
AGGGTATCTGCGTCACGAGCCGTGA

Upstream 100 bases:

>100_bases
ATCCCGTAGCGCCGTGGCACCGGAACCGGTGCCACGTCGACCGCACGCGGCGGCCCCAGGTCGTCTCGCCCAGAAAGCAC
TAAAAGGAACAGACCAACCC

Downstream 100 bases:

>100_bases
TCGACGGGGCAACCCGGCTGCCGCTTCGAGCGGCATGAAACAACGCAACGGCGCTCCGCCACGCAGGCGGCGCGCCGTTT
TTTCATGGGCGGCGCGTTTG

Product: major facilitator superfamily metabolite/H(+) symporter

Products: Proton [Cytoplasm]; 2-oxoglutarate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDVQTDQAALSAHDTRRRVFAIVGASSGNLVEWFDFYIYSFCALYFAPAFFPSGNSTTQLLNTAGVFAAGFLMRPIGGWL
FGRIADRHGRRAAMMISVLMMCGGSLVIAVLPTYAQIGALAPALLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFA
SFQYVTLIGGQLCALLVLVILQQTLSTDELKAWGWRIPFVCGAAAALISLYLRKSLDETSTSASRDKKDAGTIRGVWQHK
GAFFTVVGFTAGGSLIFYTFTTYMQKYLVNTAGMHAKTASNVMTVALLVYMLIQPVFGALSDKIGRRTSMILFGTFAVIG
TVPLMHTLKTVTSPMAAFVLITIALAIVSFYTSISGLIKAEMFPPEVRAMGVGLSYAVANAIFGGSAEYVALWFKSVGSE
ETFYWYVTALCAVSLIVSWRMRDPSKEGYLRHEP

Sequences:

>Translated_434_residues
MDVQTDQAALSAHDTRRRVFAIVGASSGNLVEWFDFYIYSFCALYFAPAFFPSGNSTTQLLNTAGVFAAGFLMRPIGGWL
FGRIADRHGRRAAMMISVLMMCGGSLVIAVLPTYAQIGALAPALLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFA
SFQYVTLIGGQLCALLVLVILQQTLSTDELKAWGWRIPFVCGAAAALISLYLRKSLDETSTSASRDKKDAGTIRGVWQHK
GAFFTVVGFTAGGSLIFYTFTTYMQKYLVNTAGMHAKTASNVMTVALLVYMLIQPVFGALSDKIGRRTSMILFGTFAVIG
TVPLMHTLKTVTSPMAAFVLITIALAIVSFYTSISGLIKAEMFPPEVRAMGVGLSYAVANAIFGGSAEYVALWFKSVGSE
ETFYWYVTALCAVSLIVSWRMRDPSKEGYLRHEP
>Mature_434_residues
MDVQTDQAALSAHDTRRRVFAIVGASSGNLVEWFDFYIYSFCALYFAPAFFPSGNSTTQLLNTAGVFAAGFLMRPIGGWL
FGRIADRHGRRAAMMISVLMMCGGSLVIAVLPTYAQIGALAPALLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFA
SFQYVTLIGGQLCALLVLVILQQTLSTDELKAWGWRIPFVCGAAAALISLYLRKSLDETSTSASRDKKDAGTIRGVWQHK
GAFFTVVGFTAGGSLIFYTFTTYMQKYLVNTAGMHAKTASNVMTVALLVYMLIQPVFGALSDKIGRRTSMILFGTFAVIG
TVPLMHTLKTVTSPMAAFVLITIALAIVSFYTSISGLIKAEMFPPEVRAMGVGLSYAVANAIFGGSAEYVALWFKSVGSE
ETFYWYVTALCAVSLIVSWRMRDPSKEGYLRHEP

Specific function: Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788942, Length=422, Percent_Identity=69.4312796208531, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1790550, Length=423, Percent_Identity=28.8416075650118, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1788292, Length=435, Percent_Identity=28.0459770114943, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789941, Length=412, Percent_Identity=31.5533980582524, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87082231, Length=325, Percent_Identity=26.1538461538462, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082404, Length=312, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 47106; Mature: 47106

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-oxoglutarate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-oxoglutarate [Periplasm] = Proton [Cytoplasm] + 2-oxoglutarate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2118499; 9205837; 9278503; 1709493; 2190187; 2053984; 8419306 [H]