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The map label for this gene is aarA [H]

Identifier: 115351567

GI number: 115351567

Start: 1661576

End: 1663495

Strand: Direct

Name: aarA [H]

Synonym: Bamb_1514

Alternate gene names: 115351567

Gene position: 1661576-1663495 (Clockwise)

Preceding gene: 115351566

Following gene: 115351568

Centisome position: 46.72

GC content: 67.66

Gene sequence:

>1920_bases
ATGAGAGAACAACATTCTTCCAGGCCGTGGTTGACCATTCTGCTGGCCGTCGTCAATACCGTGATATTCGTGCTGATGTG
GCGACAGGCGTCGTACGGTTCGCTGTCCAACCCGCTGCTGCTCGACTGGGGCGCGAACTTCGCGCCGTACACGCTCACCG
GGCAGCCGTGGCGGCTGCTGACCAGCGCGTTCCTGCACGGCAGCTGGGTCCATCTCGCGCTGAACATGTACATGCTGGTG
GTGCTCGGCACCGTGCTCGAACGCGCGGGCGGCACGCTGCGGTTCGGCGTCGCGTATCTTTTGTCCGCGCTCGGCGGCTC
GCTGCTGAGCGCGCTCTGGCATGGCTATCACGAAGTCGGCAGCACCACCTTTGCGTTCGGCGTCGCGCTGGCGTCCAGCG
GGATCCGGCCGGTCGTGAGTGTCGGTGCGTCGGGCGCACTGATGGGACTGGCGGGCGCGGCCGCGGCATTCGCGCTGCAA
CGCCGACGCGACAGCGCAGGCGATGCGCCGGTTGCCATCAACCTCGGCGCGCTCGGGCAAGTGATCGCGATCAACCTGGG
CTCGGGCTTCCTCATCTCCGGCATCGATCAGGCCGCGCATCTCGGCGGTGTGGTCGTCGGCTTCATCGCCGGTTGGCTGA
TGTACGGGGCCGGCCGCTCGATGCGCGTCGCCGTGCCGCTCGTGTTCGCGGTGCTCGGCAGCGCGGCGATGTTGTTCGCC
GCGCAGCGGGCCGGCAGCGAGGAACTGCAAGGCTGGCGTGACGCGACCCGCCGCGACGTCGAGCGCGACGCCGCGAAGCG
CCACGCGCAACAGCAGGCGGCCGCGATTGCCGAGCAGATCCGCGACGACGAGCAACACCGTCCGGCGCCCGTGTCGGCCG
AGCAGGCGGCAGGCACCGTCGTACCCGTCGGCAAGTGGCCATACGCGATGGTGCTGGGCGCATCGGGCAAACGCCTGTAC
GTGACCGACAACGACCGGAACACGCTCGTCGTCGTCGACGTCGAGCGGCACGAGGTCGTGCGCACGATCACAGGCGAGCC
GTTCGCGACGGGGCTCGACGGCTGCCCGGGGAACATGTGCCGCGGCCGCGGCGCGAGCGGCGTGTACGTGAGCCCCGACG
AGCGCTACGCGTATGTTGCGTCGATGCGCGAGAACGGCCTCGCGCGCATCGACCTGAACAGCGGTGCGATCGTCGATGGC
GTGACGCTCGGACGCTTTCCGCGCGCAATCGTTGCGTCCGCATCCAACGATAGGCTGTACGTGCTGAACAGCGTCGACGA
CACGATTTCGGTCGTCAGTCTCGCGCACTGGCCGCAGGTCATCGCGACGCTGCGGCTCGGCGATCACGATGCATCGGGCG
TCGAGTTCGGCCGTGCGCTGTCGATGTGGCTGTCGCCCGACGACCGGCGGCTGTATGCATACGCGATGCAGAAGGGCGCG
ATCGTCGCGTTCGATACGGCGACGAACGCGCAGGTAGAGACCTATCCGGTCGATGCGGATTTCATCCAGGCTCAGCCTGG
CGAGAAGGGCGCGGGCATCTGGGTCTACAACAAGTCGTCGGTTCAGTGGCGGGATGCGTCGAGCCTTGCCGTACGCGACA
GTTATCCGGTCTGCCAGGAGTCGATGCACAGCTTCGACGGCAGCGGTGACGGCTCGCTGATCGCCGTGACCGGCTATGAC
GACAAGCCGATGCGCGTGATCAAGACCGCCACGCGTCGTACCGTCGGCGAGTTTCCGGTCGCGGGCGGCGTGTCGCAGGT
GATCTTCGCGCCGGATCACAAGACGCTGTTCGCGCTCGGCGCAGCCGGCACGCTGTCGTTCCTGCGCATGGACCGTTCGC
TCGATTACCTGCAGGACGGCGGTGACGGCGAGTTCCTGTGCGCGGCGTCCGTGGCCGCCACCGACGACGATAGCGAATGA

Upstream 100 bases:

>100_bases
CGGTTCGCCGATCGGCCTCGTCACACGCTCGTTGCTTGCGGGACGCGAAATATAATGGCGCTCGCGCGGCTCACGCGCGA
TAACCCATACCAAGATCCCG

Downstream 100 bases:

>100_bases
CCGCGAGCGCGGGTGCGCGTCATCACAAAACCCGCAGAGCAAAGCACCATTTGTTGGTTCGAAATCGCCGCACGCGCTGA
TACGTTAGCGGCTTCGCGAC

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MREQHSSRPWLTILLAVVNTVIFVLMWRQASYGSLSNPLLLDWGANFAPYTLTGQPWRLLTSAFLHGSWVHLALNMYMLV
VLGTVLERAGGTLRFGVAYLLSALGGSLLSALWHGYHEVGSTTFAFGVALASSGIRPVVSVGASGALMGLAGAAAAFALQ
RRRDSAGDAPVAINLGALGQVIAINLGSGFLISGIDQAAHLGGVVVGFIAGWLMYGAGRSMRVAVPLVFAVLGSAAMLFA
AQRAGSEELQGWRDATRRDVERDAAKRHAQQQAAAIAEQIRDDEQHRPAPVSAEQAAGTVVPVGKWPYAMVLGASGKRLY
VTDNDRNTLVVVDVERHEVVRTITGEPFATGLDGCPGNMCRGRGASGVYVSPDERYAYVASMRENGLARIDLNSGAIVDG
VTLGRFPRAIVASASNDRLYVLNSVDDTISVVSLAHWPQVIATLRLGDHDASGVEFGRALSMWLSPDDRRLYAYAMQKGA
IVAFDTATNAQVETYPVDADFIQAQPGEKGAGIWVYNKSSVQWRDASSLAVRDSYPVCQESMHSFDGSGDGSLIAVTGYD
DKPMRVIKTATRRTVGEFPVAGGVSQVIFAPDHKTLFALGAAGTLSFLRMDRSLDYLQDGGDGEFLCAASVAATDDDSE

Sequences:

>Translated_639_residues
MREQHSSRPWLTILLAVVNTVIFVLMWRQASYGSLSNPLLLDWGANFAPYTLTGQPWRLLTSAFLHGSWVHLALNMYMLV
VLGTVLERAGGTLRFGVAYLLSALGGSLLSALWHGYHEVGSTTFAFGVALASSGIRPVVSVGASGALMGLAGAAAAFALQ
RRRDSAGDAPVAINLGALGQVIAINLGSGFLISGIDQAAHLGGVVVGFIAGWLMYGAGRSMRVAVPLVFAVLGSAAMLFA
AQRAGSEELQGWRDATRRDVERDAAKRHAQQQAAAIAEQIRDDEQHRPAPVSAEQAAGTVVPVGKWPYAMVLGASGKRLY
VTDNDRNTLVVVDVERHEVVRTITGEPFATGLDGCPGNMCRGRGASGVYVSPDERYAYVASMRENGLARIDLNSGAIVDG
VTLGRFPRAIVASASNDRLYVLNSVDDTISVVSLAHWPQVIATLRLGDHDASGVEFGRALSMWLSPDDRRLYAYAMQKGA
IVAFDTATNAQVETYPVDADFIQAQPGEKGAGIWVYNKSSVQWRDASSLAVRDSYPVCQESMHSFDGSGDGSLIAVTGYD
DKPMRVIKTATRRTVGEFPVAGGVSQVIFAPDHKTLFALGAAGTLSFLRMDRSLDYLQDGGDGEFLCAASVAATDDDSE
>Mature_639_residues
MREQHSSRPWLTILLAVVNTVIFVLMWRQASYGSLSNPLLLDWGANFAPYTLTGQPWRLLTSAFLHGSWVHLALNMYMLV
VLGTVLERAGGTLRFGVAYLLSALGGSLLSALWHGYHEVGSTTFAFGVALASSGIRPVVSVGASGALMGLAGAAAAFALQ
RRRDSAGDAPVAINLGALGQVIAINLGSGFLISGIDQAAHLGGVVVGFIAGWLMYGAGRSMRVAVPLVFAVLGSAAMLFA
AQRAGSEELQGWRDATRRDVERDAAKRHAQQQAAAIAEQIRDDEQHRPAPVSAEQAAGTVVPVGKWPYAMVLGASGKRLY
VTDNDRNTLVVVDVERHEVVRTITGEPFATGLDGCPGNMCRGRGASGVYVSPDERYAYVASMRENGLARIDLNSGAIVDG
VTLGRFPRAIVASASNDRLYVLNSVDDTISVVSLAHWPQVIATLRLGDHDASGVEFGRALSMWLSPDDRRLYAYAMQKGA
IVAFDTATNAQVETYPVDADFIQAQPGEKGAGIWVYNKSSVQWRDASSLAVRDSYPVCQESMHSFDGSGDGSLIAVTGYD
DKPMRVIKTATRRTVGEFPVAGGVSQVIFAPDHKTLFALGAAGTLSFLRMDRSLDYLQDGGDGEFLCAASVAATDDDSE

Specific function: Rhomboid serine protease that catalyzes intramembrane proteolysis. Mediates quorum-sensing and the subsequent regulation of target genes via activation of the Tat protein export system. Catalyzes the proteolytic activation of tatA by removal of its N- ter

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 68048; Mature: 68048

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREQHSSRPWLTILLAVVNTVIFVLMWRQASYGSLSNPLLLDWGANFAPYTLTGQPWRLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEECCCCHHHH
TSAFLHGSWVHLALNMYMLVVLGTVLERAGGTLRFGVAYLLSALGGSLLSALWHGYHEVG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
STTFAFGVALASSGIRPVVSVGASGALMGLAGAAAAFALQRRRDSAGDAPVAINLGALGQ
CHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCE
VIAINLGSGFLISGIDQAAHLGGVVVGFIAGWLMYGAGRSMRVAVPLVFAVLGSAAMLFA
EEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHH
AQRAGSEELQGWRDATRRDVERDAAKRHAQQQAAAIAEQIRDDEQHRPAPVSAEQAAGTV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHCCCCE
VPVGKWPYAMVLGASGKRLYVTDNDRNTLVVVDVERHEVVRTITGEPFATGLDGCPGNMC
EECCCCCEEEEECCCCCEEEEEECCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCC
RGRGASGVYVSPDERYAYVASMRENGLARIDLNSGAIVDGVTLGRFPRAIVASASNDRLY
CCCCCCCCEECCCCCEEEEEHHHHCCEEEEECCCCCEECCEECCCCCHHHEECCCCCEEE
VLNSVDDTISVVSLAHWPQVIATLRLGDHDASGVEFGRALSMWLSPDDRRLYAYAMQKGA
EEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHEEEECCCCCEEEEEEECCCC
IVAFDTATNAQVETYPVDADFIQAQPGEKGAGIWVYNKSSVQWRDASSLAVRDSYPVCQE
EEEEECCCCCEEEEEECCCHHEECCCCCCCCEEEEECCCCCEECCCCCEEEECCCCHHHH
SMHSFDGSGDGSLIAVTGYDDKPMRVIKTATRRTVGEFPVAGGVSQVIFAPDHKTLFALG
HHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEC
AAGTLSFLRMDRSLDYLQDGGDGEFLCAASVAATDDDSE
CCHHHHHHHHHCCHHHHHCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MREQHSSRPWLTILLAVVNTVIFVLMWRQASYGSLSNPLLLDWGANFAPYTLTGQPWRLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEECCCCHHHH
TSAFLHGSWVHLALNMYMLVVLGTVLERAGGTLRFGVAYLLSALGGSLLSALWHGYHEVG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
STTFAFGVALASSGIRPVVSVGASGALMGLAGAAAAFALQRRRDSAGDAPVAINLGALGQ
CHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCE
VIAINLGSGFLISGIDQAAHLGGVVVGFIAGWLMYGAGRSMRVAVPLVFAVLGSAAMLFA
EEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHH
AQRAGSEELQGWRDATRRDVERDAAKRHAQQQAAAIAEQIRDDEQHRPAPVSAEQAAGTV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHCCCCE
VPVGKWPYAMVLGASGKRLYVTDNDRNTLVVVDVERHEVVRTITGEPFATGLDGCPGNMC
EECCCCCEEEEECCCCCEEEEEECCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCC
RGRGASGVYVSPDERYAYVASMRENGLARIDLNSGAIVDGVTLGRFPRAIVASASNDRLY
CCCCCCCCEECCCCCEEEEEHHHHCCEEEEECCCCCEECCEECCCCCHHHEECCCCCEEE
VLNSVDDTISVVSLAHWPQVIATLRLGDHDASGVEFGRALSMWLSPDDRRLYAYAMQKGA
EEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHEEEECCCCCEEEEEEECCCC
IVAFDTATNAQVETYPVDADFIQAQPGEKGAGIWVYNKSSVQWRDASSLAVRDSYPVCQE
EEEEECCCCCEEEEEECCCHHEECCCCCCCCEEEEECCCCCEECCCCCEEEECCCCHHHH
SMHSFDGSGDGSLIAVTGYDDKPMRVIKTATRRTVGEFPVAGGVSQVIFAPDHKTLFALG
HHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEC
AAGTLSFLRMDRSLDYLQDGGDGEFLCAASVAATDDDSE
CCHHHHHHHHHCCHHHHHCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8051030 [H]