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The map label for this gene is phoR [H]

Identifier: 115351480

GI number: 115351480

Start: 1574467

End: 1576797

Strand: Direct

Name: phoR [H]

Synonym: Bamb_1427

Alternate gene names: 115351480

Gene position: 1574467-1576797 (Clockwise)

Preceding gene: 115351474

Following gene: 115351482

Centisome position: 44.27

GC content: 67.52

Gene sequence:

>2331_bases
ATGTCTGACTGGCCCCATCGTATCTGGCGAGGTGTGACGTCCGTGCGGCCCACTGCGTGGCTGTTCACCGCCGGCGTTGC
GTTGCTGGCGGCGCTCAGCTGTACGCCGGCCGCCGAGACGCTGCTGTCGCCGATCGACCGGTTGTACTGGAATCTGGTCG
CGACCCGCGTCGATCACGGCGCGCGCGACGATGTCGTCGTCGTCTCGATCGACAAGAAAACGATCGCCGAACTGGGCGGC
GGTGCGAGCTATGCACGGACGTCCCATGCGCAGGTGCTCGATCGTCTCGGCGGCGCATCGAGCGTCGTGCTCGACATGAC
GATGTTCGGCTCGACGCCCGGCGACGATGCGCTCGCGGCCGCGATCACGCGGCAAGGGCGCGTCGTGCTGCCTGCCCACG
TGTCGCCGGAGAGCACGCGTGCCGACACCGTGCTGCTGCCCGCGCGGCAGTTGCGCGGCGCGGCGGCGGCCGTTGGTCAG
CGCAGCGTCGTGCTCGGCAGCGATCATCTGGTGCAAGGCATCGTGCCGTACGTGCGGGCGGACAATTCGGACGACGAGTT
CCCGCACGTCGCGCTGCAGGCGATCCGCGTGGCGGGCGCGTCGCTGCCGGCCGGCGACGTGCGTCTCCAGGTACAGGATC
ACGTATCCAAGATGGGGCGCGTCGCAGCTCACTCGCTCGCGCTGTTCCTGCCGGCCCGCTTCGACCTCGACCGCTATTCG
TATGTCGACGTGCTGAAGGGGCGCATCCCGGAGTCGGCGTGGCGCGGCCGCATCGTGTTCATCGGCGACACGATGTCGGA
TCTTTCCGGCGTGTACGACCTGTCGACGTCGGAAGGTGGACGGCTGCGGCGCGTCGAAGTCGACGCGATGGTGACGCAGG
CGCTGCTCGACGGCCACATCCTGTGGCGTGAGCCGGTGGCGGTTCAGGTCGTCGTCAGCATCGCGGTCGCGACGGGGATG
CTGCTGATCTGCATGCTGGTGCCGGGCTGGCGCATGTACGCATTCGCGCTCGGGGGGCTGGCCATGTTCGTCGCCGTCGA
ACTGGTGCTGCTCGTGCGTTGGTCATGCTGGACGCCGCTCGGGCCGTTGCTTGCCGTGTGCGTATTGATTTTCGCGGTGT
GCGGCTGGCGGCGCGCCGGCAGCGTGCGGACATTCCTGTTGAACGAATACGGGATGCTGCGCGGGCTTGCCGGCCAGCAC
GCGTTCATCGGCTTGCCGCACGCGGCAGGCGTCGATGCCGCGATGCCGACGACGGACGAAGTCGAGATTGCGATGCAGAG
CATTCGCGCGTGGCAGACGGCCTATGTCGACATGATTGAAACGCTGCCGTATCCCATCTTCGTCGAACAGCACGGCAAGC
TGTTGATGTGCAATGCGCGCGGCCGGGCGATGCTGCAGACGCTCGACGCGGACGGCGACGCGGACGGCGATGCGGCCGCA
GGGCGCGTGCTGGCGATCGCGCGCGGCGAAGTGCTGACCGCGAAGGCGACCGGCAAGATCCACTCGGCCGAGCTGGTGCT
GAACGGGCGCACGCAGATGATGATGGTGACGCCGTTCGGCGATGGCGACCGGCACAGTTCGACGGCGAGCATGATCTGTC
TCGTCGATATCCACAACATCAAGGCGGCGGTCGAAAACGACCGGCTGACGCTGCGGCACATGGCGCACGACCTGCGCAAC
CCGCTTTCGACGGTGCTGTCGCTGCTCGAAGCGCACAACCACGCCGACGGCGCGACCGACGAGGATTTTCTGGCGGACCT
GCACAAGCTCGTCGACTACAGCCTGCGCGTCGCGCAGGATTTCACGCAGCTGTCGCGCGCCGAACACCTCGATACGCGTG
CGTATGTGCCGGTGTCGGCGAACGATCTGGCGGCGGAAGCGGTCGATCAGATCTGGCACAGCGCGAACGGTAAGCGAATC
CGCGTCGAGGGGCCGCATTACGACGGCGACGACGTGTTCGTGCTCGGCAATCGCGACATGCTGTTGCGTGCATTGACCAA
CCTGCTCGACAACGCGATCAAATACTCGGCCGAGGAGACGGCCGTCGACGTCTGGATCGACGCCGACGACCGGCAGGTGT
CGGTGGCCGTGCAGGACCAGGGGTGCGGCATCCCGGCCGACGCGATGCCGAGGCTGTTCGAGCCGTTCTTCCAGGTCGAC
GGCACGTATCGCGACGCCAGCCGCGGGGTCGGCCTCGGGCTGCCGTTCGTGAAGGCGGTGATCGAGCGCCACGGCGGATC
GGTCGACGTGACGTCGACGCCGGGGCAGGGCAGCCGCTTCACCGTGCGTTTGCCGAGGACCGTTGCGGTAACGACGCTCG
ACGACGCGTGA

Upstream 100 bases:

>100_bases
GCGCGCGACGAAGAAAGCAGCCGATTTGCCACGACCAGTCAGGGCATGCGCGGACGCAGCGAACTCGGGCGAATAAAACA
ATAAACAGGAATGCCATCCC

Downstream 100 bases:

>100_bases
TCGGCGGAGGCCGTGGAACGGCGGAACGGGTGTGCAATGCGTTGAAGTCGGAAAGGGATTGAAGTCAGCGTGATGGAAGG
CCGGGCCCGGTATTGCACGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MSDWPHRIWRGVTSVRPTAWLFTAGVALLAALSCTPAAETLLSPIDRLYWNLVATRVDHGARDDVVVVSIDKKTIAELGG
GASYARTSHAQVLDRLGGASSVVLDMTMFGSTPGDDALAAAITRQGRVVLPAHVSPESTRADTVLLPARQLRGAAAAVGQ
RSVVLGSDHLVQGIVPYVRADNSDDEFPHVALQAIRVAGASLPAGDVRLQVQDHVSKMGRVAAHSLALFLPARFDLDRYS
YVDVLKGRIPESAWRGRIVFIGDTMSDLSGVYDLSTSEGGRLRRVEVDAMVTQALLDGHILWREPVAVQVVVSIAVATGM
LLICMLVPGWRMYAFALGGLAMFVAVELVLLVRWSCWTPLGPLLAVCVLIFAVCGWRRAGSVRTFLLNEYGMLRGLAGQH
AFIGLPHAAGVDAAMPTTDEVEIAMQSIRAWQTAYVDMIETLPYPIFVEQHGKLLMCNARGRAMLQTLDADGDADGDAAA
GRVLAIARGEVLTAKATGKIHSAELVLNGRTQMMMVTPFGDGDRHSSTASMICLVDIHNIKAAVENDRLTLRHMAHDLRN
PLSTVLSLLEAHNHADGATDEDFLADLHKLVDYSLRVAQDFTQLSRAEHLDTRAYVPVSANDLAAEAVDQIWHSANGKRI
RVEGPHYDGDDVFVLGNRDMLLRALTNLLDNAIKYSAEETAVDVWIDADDRQVSVAVQDQGCGIPADAMPRLFEPFFQVD
GTYRDASRGVGLGLPFVKAVIERHGGSVDVTSTPGQGSRFTVRLPRTVAVTTLDDA

Sequences:

>Translated_776_residues
MSDWPHRIWRGVTSVRPTAWLFTAGVALLAALSCTPAAETLLSPIDRLYWNLVATRVDHGARDDVVVVSIDKKTIAELGG
GASYARTSHAQVLDRLGGASSVVLDMTMFGSTPGDDALAAAITRQGRVVLPAHVSPESTRADTVLLPARQLRGAAAAVGQ
RSVVLGSDHLVQGIVPYVRADNSDDEFPHVALQAIRVAGASLPAGDVRLQVQDHVSKMGRVAAHSLALFLPARFDLDRYS
YVDVLKGRIPESAWRGRIVFIGDTMSDLSGVYDLSTSEGGRLRRVEVDAMVTQALLDGHILWREPVAVQVVVSIAVATGM
LLICMLVPGWRMYAFALGGLAMFVAVELVLLVRWSCWTPLGPLLAVCVLIFAVCGWRRAGSVRTFLLNEYGMLRGLAGQH
AFIGLPHAAGVDAAMPTTDEVEIAMQSIRAWQTAYVDMIETLPYPIFVEQHGKLLMCNARGRAMLQTLDADGDADGDAAA
GRVLAIARGEVLTAKATGKIHSAELVLNGRTQMMMVTPFGDGDRHSSTASMICLVDIHNIKAAVENDRLTLRHMAHDLRN
PLSTVLSLLEAHNHADGATDEDFLADLHKLVDYSLRVAQDFTQLSRAEHLDTRAYVPVSANDLAAEAVDQIWHSANGKRI
RVEGPHYDGDDVFVLGNRDMLLRALTNLLDNAIKYSAEETAVDVWIDADDRQVSVAVQDQGCGIPADAMPRLFEPFFQVD
GTYRDASRGVGLGLPFVKAVIERHGGSVDVTSTPGQGSRFTVRLPRTVAVTTLDDA
>Mature_775_residues
SDWPHRIWRGVTSVRPTAWLFTAGVALLAALSCTPAAETLLSPIDRLYWNLVATRVDHGARDDVVVVSIDKKTIAELGGG
ASYARTSHAQVLDRLGGASSVVLDMTMFGSTPGDDALAAAITRQGRVVLPAHVSPESTRADTVLLPARQLRGAAAAVGQR
SVVLGSDHLVQGIVPYVRADNSDDEFPHVALQAIRVAGASLPAGDVRLQVQDHVSKMGRVAAHSLALFLPARFDLDRYSY
VDVLKGRIPESAWRGRIVFIGDTMSDLSGVYDLSTSEGGRLRRVEVDAMVTQALLDGHILWREPVAVQVVVSIAVATGML
LICMLVPGWRMYAFALGGLAMFVAVELVLLVRWSCWTPLGPLLAVCVLIFAVCGWRRAGSVRTFLLNEYGMLRGLAGQHA
FIGLPHAAGVDAAMPTTDEVEIAMQSIRAWQTAYVDMIETLPYPIFVEQHGKLLMCNARGRAMLQTLDADGDADGDAAAG
RVLAIARGEVLTAKATGKIHSAELVLNGRTQMMMVTPFGDGDRHSSTASMICLVDIHNIKAAVENDRLTLRHMAHDLRNP
LSTVLSLLEAHNHADGATDEDFLADLHKLVDYSLRVAQDFTQLSRAEHLDTRAYVPVSANDLAAEAVDQIWHSANGKRIR
VEGPHYDGDDVFVLGNRDMLLRALTNLLDNAIKYSAEETAVDVWIDADDRQVSVAVQDQGCGIPADAMPRLFEPFFQVDG
TYRDASRGVGLGLPFVKAVIERHGGSVDVTSTPGQGSRFTVRLPRTVAVTTLDDA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=29.2237442922374, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=28.2407407407407, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=28.0542986425339, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786600, Length=284, Percent_Identity=26.7605633802817, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=25.9414225941423, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=29.6943231441048, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=198, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=27.3148148148148, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=24.896265560166, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=130, Percent_Identity=30, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1790551, Length=253, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83852; Mature: 83721

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWPHRIWRGVTSVRPTAWLFTAGVALLAALSCTPAAETLLSPIDRLYWNLVATRVDHG
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ARDDVVVVSIDKKTIAELGGGASYARTSHAQVLDRLGGASSVVLDMTMFGSTPGDDALAA
CCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHH
AITRQGRVVLPAHVSPESTRADTVLLPARQLRGAAAAVGQRSVVLGSDHLVQGIVPYVRA
HHHCCCCEEEECCCCCCCCCCCEEEECHHHHCCHHHHCCCCEEEECCCHHHHHHHHHHCC
DNSDDEFPHVALQAIRVAGASLPAGDVRLQVQDHVSKMGRVAAHSLALFLPARFDLDRYS
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHEECCCCCCCHHH
YVDVLKGRIPESAWRGRIVFIGDTMSDLSGVYDLSTSEGGRLRRVEVDAMVTQALLDGHI
HHHHHHCCCCCHHHCCEEEEEECCHHHHCCCEECCCCCCCEEEEEEHHHHHHHHHHCCCE
LWREPVAVQVVVSIAVATGMLLICMLVPGWRMYAFALGGLAMFVAVELVLLVRWSCWTPL
EECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GPLLAVCVLIFAVCGWRRAGSVRTFLLNEYGMLRGLAGQHAFIGLPHAAGVDAAMPTTDE
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHH
VEIAMQSIRAWQTAYVDMIETLPYPIFVEQHGKLLMCNARGRAMLQTLDADGDADGDAAA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEHHEECCCCCCCCCCCC
GRVLAIARGEVLTAKATGKIHSAELVLNGRTQMMMVTPFGDGDRHSSTASMICLVDIHNI
CEEEEEECCCEEEEECCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECHH
KAAVENDRLTLRHMAHDLRNPLSTVLSLLEAHNHADGATDEDFLADLHKLVDYSLRVAQD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FTQLSRAEHLDTRAYVPVSANDLAAEAVDQIWHSANGKRIRVEGPHYDGDDVFVLGNRDM
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCHHH
LLRALTNLLDNAIKYSAEETAVDVWIDADDRQVSVAVQDQGCGIPADAMPRLFEPFFQVD
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCC
GTYRDASRGVGLGLPFVKAVIERHGGSVDVTSTPGQGSRFTVRLPRTVAVTTLDDA
CCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCEEEEEEECCC
>Mature Secondary Structure 
SDWPHRIWRGVTSVRPTAWLFTAGVALLAALSCTPAAETLLSPIDRLYWNLVATRVDHG
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ARDDVVVVSIDKKTIAELGGGASYARTSHAQVLDRLGGASSVVLDMTMFGSTPGDDALAA
CCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHH
AITRQGRVVLPAHVSPESTRADTVLLPARQLRGAAAAVGQRSVVLGSDHLVQGIVPYVRA
HHHCCCCEEEECCCCCCCCCCCEEEECHHHHCCHHHHCCCCEEEECCCHHHHHHHHHHCC
DNSDDEFPHVALQAIRVAGASLPAGDVRLQVQDHVSKMGRVAAHSLALFLPARFDLDRYS
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHEECCCCCCCHHH
YVDVLKGRIPESAWRGRIVFIGDTMSDLSGVYDLSTSEGGRLRRVEVDAMVTQALLDGHI
HHHHHHCCCCCHHHCCEEEEEECCHHHHCCCEECCCCCCCEEEEEEHHHHHHHHHHCCCE
LWREPVAVQVVVSIAVATGMLLICMLVPGWRMYAFALGGLAMFVAVELVLLVRWSCWTPL
EECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GPLLAVCVLIFAVCGWRRAGSVRTFLLNEYGMLRGLAGQHAFIGLPHAAGVDAAMPTTDE
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHH
VEIAMQSIRAWQTAYVDMIETLPYPIFVEQHGKLLMCNARGRAMLQTLDADGDADGDAAA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEHHEECCCCCCCCCCCC
GRVLAIARGEVLTAKATGKIHSAELVLNGRTQMMMVTPFGDGDRHSSTASMICLVDIHNI
CEEEEEECCCEEEEECCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECHH
KAAVENDRLTLRHMAHDLRNPLSTVLSLLEAHNHADGATDEDFLADLHKLVDYSLRVAQD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FTQLSRAEHLDTRAYVPVSANDLAAEAVDQIWHSANGKRIRVEGPHYDGDDVFVLGNRDM
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCHHH
LLRALTNLLDNAIKYSAEETAVDVWIDADDRQVSVAVQDQGCGIPADAMPRLFEPFFQVD
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCC
GTYRDASRGVGLGLPFVKAVIERHGGSVDVTSTPGQGSRFTVRLPRTVAVTTLDDA
CCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]