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The map label for this gene is ychM [C]

Identifier: 115351474

GI number: 115351474

Start: 1565252

End: 1566970

Strand: Direct

Name: ychM [C]

Synonym: Bamb_1421

Alternate gene names: 115351474

Gene position: 1565252-1566970 (Clockwise)

Preceding gene: 115351473

Following gene: 115351480

Centisome position: 44.01

GC content: 69.63

Gene sequence:

>1719_bases
ATGACGACCGTCTCGCCCCGTCCGGATGCCGGCCCGCAGCATCCCGAGCATTTCGCCGCACTCGATGCGGCAACGCCGCG
GCCCACGCGGCGCATCGGCCTTGACGCGCTGGCCGGTCTGTCGATCGCCGGGCTGCTGATTCCGGAGGCGGTCGCATATG
CGGGGCTCGCCAACCTGCCGCCGCAGGCCGGCCTCATCGCGTTGCTGTCGGGGCTCGTGGTGTATGCGCTGACCGGCAGC
AGCCGTTTTGCGATCGTGTCGTCGACCTCGTCGTCGGCGGCCGTGCTCGCGGCGACCGTGCTGGCCGAATCGGGGATGGC
GCTCGCCGCGCAGCTCGCGCTGGCGGCCGCACTCGTCGCGATGACCGGCGTGCTGTTCATCCTGGCGGGCGCGGCACGGC
TCGGCGGCATGTCGGATTTCATCGCGCGTCCGGTGCTGCGCGGGTTCACGTTCGGACTCGCGCTGACGATCGTCCTCAAG
CAACTGCCGAAGATCCTCGCGATCTCCGTGCAGCACAGCGATGCGCCGCATGTCGCGCTCGACCTCCTCGCCGGTGCGCC
GCGTGCGAACCTCGCGAGCGTCGCGCTCGGCGGGAGCGCGCTTGCGCTGCTGTTCGTGCTCGGGCGCAGCAAGCGGGTGC
CGGCCACACTCGTCGTGATCGTGCTGTCGATCGCGGCCGGCTATATGGTCGACTGGCAGCACTACGGGATCGCGATCGTC
GGCCACATCGATTTCCAGCACCTCGCATTCGGGCTGCCGCAACTCGACCGCAACGCATGGATGCAGACGGTCGAGCTTGC
TTTCGCGCTGATGCTGATCCTGTATGCGGAATCGTACGGATCGATCCGCAACTTCGCGCTGAAGCACGGCGACAGCGTGT
CGCCGAACCGCGACCTCGTCGCGCTCGGCTGCGCGAACCTCGTGTCGGGGCTGCTGCACGGGATGCCGGTCGGCGCCGGC
TACTCGGCGACAGCGGCGAACGAGGCGGCCGGCGCGCAATCGCGTTTGTCGAGCCTGTGGGCGGCCGGCGTGGTCGCGCT
GATCGTGTGGCTGCTGCTGCCGCAGCTCGCGCGCACGCCGGAGCCCGTGCTCGCGGCGATCGTGATCTTCGCGGTCAGTC
ATTCGCTGCATCCGTCGGTGTTCCGGCCGTACTGGGTCTGGCATCGCGACCGGCTCGTCGTGGCCGCCGCGCTGCTCGCC
GTGCTCGTGCTCGGCGTGCTGCACGGGCTGCTCGCGGCCGTCGGCGTGAGCCTGCTGCTGACGCTGCGCAAGTTGTCGGA
GCCGAACGTCAGCGTGCTCGGCCGGCTGCGCGACGGGCACGACTTCGTCGACGTCGCGAATCACGCCGATGCGAAGCCGA
TACCCGGCGTGCTGATCGTGCGGCCCGAGGCGCAGCTGTTCTTCGCGAACGCCGACCGGATGCTCAATCGCGTGCGCGCG
CTGCTGAAGGCCGCGCCCGATACGCATACCGTGATGCTGAGTCTCGAGGAAACGCCGGACGTCGACGGCACGACGATCGA
GTCGTTGCGCACGTTCGCGGCCGAATGTGCGGCACGCGGGTTGCAGTTCGCGATCGTGCGGCTCAAGGAGCACGCGCTGC
ATGCGCTGAGTCGCGCGACCGACGACACGCTGCGTGACGCGGCGATGTCGGAGCTGAGCGTCGACGAGAGCCTGCAACTG
CTGCAGGCGCGCGGCACTGTCGGGAAGGCAGGCGTGTGA

Upstream 100 bases:

>100_bases
CTCGCTGCGCCGCGCACACGACCAGGACGCGCGCTATCTGCCCGGCTGGTCGGGTGTCATCGCCGCCAAACCCTGACATG
CGCACGGCGCCTATCGCCTC

Downstream 100 bases:

>100_bases
GCCTGCGGGGCACGCGCGCCGGCTAGCGCTTCGTGCCGCCTAGTGCGATAGCGCGGCGTCGGCCGGTTCGGCGCGCGCGC
GGCTGGCGATGACGTCGGCG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTTVSPRPDAGPQHPEHFAALDAATPRPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGS
SRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVAMTGVLFILAGAARLGGMSDFIARPVLRGFTFGLALTIVLK
QLPKILAISVQHSDAPHVALDLLAGAPRANLASVALGGSALALLFVLGRSKRVPATLVVIVLSIAAGYMVDWQHYGIAIV
GHIDFQHLAFGLPQLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATAANEAAGAQSRLSSLWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWVWHRDRLVVAAALLA
VLVLGVLHGLLAAVGVSLLLTLRKLSEPNVSVLGRLRDGHDFVDVANHADAKPIPGVLIVRPEAQLFFANADRMLNRVRA
LLKAAPDTHTVMLSLEETPDVDGTTIESLRTFAAECAARGLQFAIVRLKEHALHALSRATDDTLRDAAMSELSVDESLQL
LQARGTVGKAGV

Sequences:

>Translated_572_residues
MTTVSPRPDAGPQHPEHFAALDAATPRPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGS
SRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVAMTGVLFILAGAARLGGMSDFIARPVLRGFTFGLALTIVLK
QLPKILAISVQHSDAPHVALDLLAGAPRANLASVALGGSALALLFVLGRSKRVPATLVVIVLSIAAGYMVDWQHYGIAIV
GHIDFQHLAFGLPQLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATAANEAAGAQSRLSSLWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWVWHRDRLVVAAALLA
VLVLGVLHGLLAAVGVSLLLTLRKLSEPNVSVLGRLRDGHDFVDVANHADAKPIPGVLIVRPEAQLFFANADRMLNRVRA
LLKAAPDTHTVMLSLEETPDVDGTTIESLRTFAAECAARGLQFAIVRLKEHALHALSRATDDTLRDAAMSELSVDESLQL
LQARGTVGKAGV
>Mature_571_residues
TTVSPRPDAGPQHPEHFAALDAATPRPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGSS
RFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVAMTGVLFILAGAARLGGMSDFIARPVLRGFTFGLALTIVLKQ
LPKILAISVQHSDAPHVALDLLAGAPRANLASVALGGSALALLFVLGRSKRVPATLVVIVLSIAAGYMVDWQHYGIAIVG
HIDFQHLAFGLPQLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLVALGCANLVSGLLHGMPVGAGY
SATAANEAAGAQSRLSSLWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWVWHRDRLVVAAALLAV
LVLGVLHGLLAAVGVSLLLTLRKLSEPNVSVLGRLRDGHDFVDVANHADAKPIPGVLIVRPEAQLFFANADRMLNRVRAL
LKAAPDTHTVMLSLEETPDVDGTTIESLRTFAAECAARGLQFAIVRLKEHALHALSRATDDTLRDAAMSELSVDESLQLL
QARGTVGKAGV

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721255, Length=461, Percent_Identity=27.5488069414317, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI94721253, Length=461, Percent_Identity=27.5488069414317, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI94721259, Length=461, Percent_Identity=27.5488069414317, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI94721257, Length=461, Percent_Identity=27.5488069414317, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI39752683, Length=481, Percent_Identity=23.7006237006237, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI45827800, Length=481, Percent_Identity=23.7006237006237, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI47131207, Length=507, Percent_Identity=27.6134122287968, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI20336272, Length=507, Percent_Identity=27.6134122287968, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI16418413, Length=507, Percent_Identity=24.0631163708087, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI217272867, Length=507, Percent_Identity=24.0631163708087, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI269784651, Length=478, Percent_Identity=24.0585774058577, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4557535, Length=524, Percent_Identity=24.0458015267176, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI45827802, Length=439, Percent_Identity=22.7790432801822, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI100913030, Length=488, Percent_Identity=22.7459016393443, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI4505697, Length=485, Percent_Identity=21.4432989690722, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI20336282, Length=490, Percent_Identity=21.6326530612245, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI16306483, Length=490, Percent_Identity=21.4285714285714, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI262206105, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206075, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206069, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206063, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87081859, Length=337, Percent_Identity=26.4094955489614, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551690, Length=510, Percent_Identity=24.7058823529412, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17566848, Length=555, Percent_Identity=24.6846846846847, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193203292, Length=502, Percent_Identity=23.9043824701195, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86565215, Length=504, Percent_Identity=23.4126984126984, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86564196, Length=498, Percent_Identity=21.6867469879518, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI86564876, Length=526, Percent_Identity=20.722433460076, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562578, Length=529, Percent_Identity=24.3856332703214, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=489, Percent_Identity=24.3353783231084, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24649801, Length=441, Percent_Identity=26.530612244898, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24651449, Length=446, Percent_Identity=25.1121076233184, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24666186, Length=516, Percent_Identity=24.031007751938, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24663084, Length=468, Percent_Identity=25.4273504273504, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357695, Length=468, Percent_Identity=25.4273504273504, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19922482, Length=557, Percent_Identity=22.262118491921, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21358229, Length=446, Percent_Identity=24.6636771300448, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21358633, Length=566, Percent_Identity=22.6148409893993, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI85815873, Length=142, Percent_Identity=32.3943661971831, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59848; Mature: 59716

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVSPRPDAGPQHPEHFAALDAATPRPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVA
CCCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MTGVLFILAGAARLGGMSDFIARPVLRGFTFGLALTIVLKQLPKILAISVQHSDAPHVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
DLLAGAPRANLASVALGGSALALLFVLGRSKRVPATLVVIVLSIAAGYMVDWQHYGIAIV
HHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCEEEE
GHIDFQHLAFGLPQLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLV
EECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATAANEAAGAQSRLSSLWAAGVVALIVWLLLPQLARTP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVLAAIVIFAVSHSLHPSVFRPYWVWHRDRLVVAAALLAVLVLGVLHGLLAAVGVSLLL
HHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLSEPNVSVLGRLRDGHDFVDVANHADAKPIPGVLIVRPEAQLFFANADRMLNRVRA
HHHHCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LLKAAPDTHTVMLSLEETPDVDGTTIESLRTFAAECAARGLQFAIVRLKEHALHALSRAT
HHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
DDTLRDAAMSELSVDESLQLLQARGTVGKAGV
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTVSPRPDAGPQHPEHFAALDAATPRPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVA
CCCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MTGVLFILAGAARLGGMSDFIARPVLRGFTFGLALTIVLKQLPKILAISVQHSDAPHVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
DLLAGAPRANLASVALGGSALALLFVLGRSKRVPATLVVIVLSIAAGYMVDWQHYGIAIV
HHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCEEEE
GHIDFQHLAFGLPQLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLV
EECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATAANEAAGAQSRLSSLWAAGVVALIVWLLLPQLARTP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVLAAIVIFAVSHSLHPSVFRPYWVWHRDRLVVAAALLAVLVLGVLHGLLAAVGVSLLL
HHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLSEPNVSVLGRLRDGHDFVDVANHADAKPIPGVLIVRPEAQLFFANADRMLNRVRA
HHHHCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LLKAAPDTHTVMLSLEETPDVDGTTIESLRTFAAECAARGLQFAIVRLKEHALHALSRAT
HHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
DDTLRDAAMSELSVDESLQLLQARGTVGKAGV
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]