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The map label for this gene is hmgA [H]

Identifier: 115350755

GI number: 115350755

Start: 777557

End: 778891

Strand: Direct

Name: hmgA [H]

Synonym: Bamb_0701

Alternate gene names: 115350755

Gene position: 777557-778891 (Clockwise)

Preceding gene: 115350754

Following gene: 115350756

Centisome position: 21.86

GC content: 68.24

Gene sequence:

>1335_bases
ATGACGCTTGACCTGTCGAAACCGGCAACCGCCGGCTACCTGAGCGGATTCGCGAACGAATTCGCGACCGAGGCGCTGCC
CGGCGCGCTGCCGCACGGCCGCAATTCGCCGCAGCGCGCGCCGTACGGCTTGTATGCGGAGCAACTGTCGGGCACCGCGT
TTACCGCGCCGCGCGGCCACAACCGCCGCTCGTGGCTGTACCGGATCCGGCCGGCGGCCGTGCACCGGCCGTTCGAGCCG
TTCACGGGCCCGCAGCGGCTCGTGTCGGAATTCGGCGACTCCGCCGACGTGCCGCCGACGCCGCCGAACCAGCTGCGCTG
GGATCCGCTGCCGATGCCGGTCGAGCCGACCGATTTCGTCGAAGGGCTCGTGACGATGGCCGGCAACGGCTCGGCGGCCG
CGATGAACGGCTGCGCGATCCACCTGTATGCGGCGAACCGCTCGATGCAGGACCGTTTCTTCTACAGCGCCGACGGCGAA
CTGCTGATCGTGCCGCAGCAGGGGCGGCTCTTCATCGCGACCGAATTCGGCCGGCTCGACGTCGAGCCGTTCGAGATCGC
GGTGATCCCGCGCGGCGTGCGTTTTTCCGTCGCGCTGCCGGACGGCGACGCGCGCGGCTACATCTGCGAGAACTTCGGCG
CGCTGCTGCGCCTGCCGGACCTCGGCCCGATCGGCTCGAACGGGCTCGCGAACCCGCGCGATTTCCTGACGCCGCAGGCC
GCATACGAGGATCGCGAAGGCGCGTTCGAGCTGGTCGCGAAGCTGAACGGACGCCTCTGGCGCGCGGACATCGGCCATTC
GCCGTTCGACGTCGTCGCGTGGCACGGCAACTACGCGCCGTACAAATACGACCTGCGCCTGTTCAACACGATCGGCTCGA
TCAGCTTCGACCATCCGGACCCGTCGATCTTCCTGGTGCTGCAGTCGCAGAGCGACACGCCGGGCGTCGACGCGATCGAC
TTCGTGATCTTCCCGCCGCGCTGGCTCGCGGCCGAGGATACGTTCCGCCCGCCGTGGTTCCATCGCAATGTCGCGAGCGA
GTTCATGGGGCTCGTGCACGGCGCGTACGACGCGAAGGCCGAGGGCTTCGTGCCGGGCGGCGCGAGCCTGCACAACTGCA
TGTCGGGTCACGGGCCCGACGCGGACACGTTCGAGAAGGCGTCGGCGAGCGACACGACGAAGCCGCACAAGGTCGACGCG
ACGATGGCGTTCATGTTCGAAACCCGCACGCTGATCCGTCCGACGCGCTACGCGCTCGACACCGCGCAGCTGCAGCCCGA
CTACTTCGAATGCTGGCAAGGCATCAGGAAACATTTCAATCCGGAGCAACCATGA

Upstream 100 bases:

>100_bases
GCTGTGCTCGGCGCTGTTCGTGCTCGGGCTGGCCGGCGTAACGCGGCGCGGCGGTGCGCAGGCGCCGAACGCGGCCATGA
ATTGATGGAGAAAGGAAACG

Downstream 100 bases:

>100_bases
GCGAACCCCAAGACTGGCGCGCGACACTCGATCCGGCTCGCAAGAGCTGGGTCGAGACGGCGAACGATCCCGCCTGCGAT
TTCCCGATCCAGAACCTGCC

Product: homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEP
FTGPQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVEGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGE
LLIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFSVALPDGDARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
AYEDREGAFELVAKLNGRLWRADIGHSPFDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQSQSDTPGVDAID
FVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDA
TMAFMFETRTLIRPTRYALDTAQLQPDYFECWQGIRKHFNPEQP

Sequences:

>Translated_444_residues
MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEP
FTGPQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVEGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGE
LLIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFSVALPDGDARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
AYEDREGAFELVAKLNGRLWRADIGHSPFDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQSQSDTPGVDAID
FVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDA
TMAFMFETRTLIRPTRYALDTAQLQPDYFECWQGIRKHFNPEQP
>Mature_443_residues
TLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEPF
TGPQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVEGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGEL
LIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFSVALPDGDARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQAA
YEDREGAFELVAKLNGRLWRADIGHSPFDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQSQSDTPGVDAIDF
VIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDAT
MAFMFETRTLIRPTRYALDTAQLQPDYFECWQGIRKHFNPEQP

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

Organism=Homo sapiens, GI115527117, Length=441, Percent_Identity=52.8344671201814, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17507969, Length=432, Percent_Identity=54.3981481481482, Blast_Score=457, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24583650, Length=434, Percent_Identity=52.3041474654378, Blast_Score=444, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR022950 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: =1.13.11.5 [H]

Molecular weight: Translated: 49033; Mature: 48901

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGH
CEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCC
NRRSWLYRIRPAAVHRPFEPFTGPQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFV
CCCCEEEEECHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
EGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRLD
HHHHHCCCCCCCEEECCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCCC
VEPFEIAVIPRGVRFSVALPDGDARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
CCCEEEEEECCCEEEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCHHHCCCCH
AYEDREGAFELVAKLNGRLWRADIGHSPFDVVAWHGNYAPYKYDLRLFNTIGSISFDHPD
HCCCCCHHHHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECCCCCEECCCC
PSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKA
CEEEEEEECCCCCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
EGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTRYALD
CCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCHHHHHH
TAQLQPDYFECWQGIRKHFNPEQP
HHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGH
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCC
NRRSWLYRIRPAAVHRPFEPFTGPQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFV
CCCCEEEEECHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
EGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRLD
HHHHHCCCCCCCEEECCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCCC
VEPFEIAVIPRGVRFSVALPDGDARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
CCCEEEEEECCCEEEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCHHHCCCCH
AYEDREGAFELVAKLNGRLWRADIGHSPFDVVAWHGNYAPYKYDLRLFNTIGSISFDHPD
HCCCCCHHHHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECCCCCEECCCC
PSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKA
CEEEEEEECCCCCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
EGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTRYALD
CCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCHHHHHH
TAQLQPDYFECWQGIRKHFNPEQP
HHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA