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The map label for this gene is dsbC [H]

Identifier: 115350485

GI number: 115350485

Start: 482599

End: 483327

Strand: Direct

Name: dsbC [H]

Synonym: Bamb_0431

Alternate gene names: 115350485

Gene position: 482599-483327 (Clockwise)

Preceding gene: 115350484

Following gene: 115350486

Centisome position: 13.57

GC content: 64.88

Gene sequence:

>729_bases
ATGAAAAAAACGATCCGCATCGCGTCGCTGGCGCTGGCCGTCACGATGGCGACGCTTGGCTGCACCGCGCAGGCCGACCA
GACCACCGACAAGTTGAAAGCCACGCTGCAAGCGCGTCTGGGCAGCGACGCGCCGATCAAGAGCGTGTCGAAATCGCCGG
TCGCGGGCCTGTATGAAGTCAACCTCGGCACGCAGATCATCTATAGCGATGCAGCCGGCGACTACGTGCTGCTCGGCGAC
CTCGTCGACACCAAGACGCACAAGAATCTGACCGACGCGCGCCTGTCCGACCTGAACAAGATCGACTTCGCGAGCCTGCC
GCTCGCGAACGCGATCAAGGTCGTCAAGGGCAACGGCGCACGCAAGATCGCGGTGTTCTCCGATCCGAACTGCCCGTACT
GCAAGCGGCTCGAGACGACGCTTCAGTCGGTCGACAACGTGACCGTCTACACGTTCCTGTACCCGGTGCTGTCGCCCGAT
TCGACCACGAAGTCGAAGGCGATCTGGTGCGCGACCGACCGCGCGAAAAGCTGGGAGGGCTGGATGCTCGACCATCGCGC
ACCGTCCGGCGCCGGCAACTGCGATACGAGCGCGCTCGACAAGAACCTCGCGCTCGGCCGCGGGATGAACGTCACGGGCA
CGCCGACGATCTTCCTGCCCGACGGCCGTCGCCTGCCGGGCGCGGTGTCGGCCGATCAGCTGAACCAGGCGCTCGCGTCG
AGCAAGTAA

Upstream 100 bases:

>100_bases
GCTCGGCTGATCGAACCTTCGCGCGCCCGGCCTGTCGGACAGGGCTCCGTTACGGCGTACACTGTGACGTGCACTCCGAT
TGAGCTGAAGGAACAACAGG

Downstream 100 bases:

>100_bases
CCGACCGGCACGCCGGGCCGCATGGCCCGGCCAGCGAGGGGCGCCCGTGGTATCTGCCGGCGCCTCTCTTCGTTTCCGCC
GCCATATTCCGTCCGATTTC

Product: protein-disulfide isomerase-like protein

Products: 3-oxo-D 4-steroid; protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKKTIRIASLALAVTMATLGCTAQADQTTDKLKATLQARLGSDAPIKSVSKSPVAGLYEVNLGTQIIYSDAAGDYVLLGD
LVDTKTHKNLTDARLSDLNKIDFASLPLANAIKVVKGNGARKIAVFSDPNCPYCKRLETTLQSVDNVTVYTFLYPVLSPD
STTKSKAIWCATDRAKSWEGWMLDHRAPSGAGNCDTSALDKNLALGRGMNVTGTPTIFLPDGRRLPGAVSADQLNQALAS
SK

Sequences:

>Translated_242_residues
MKKTIRIASLALAVTMATLGCTAQADQTTDKLKATLQARLGSDAPIKSVSKSPVAGLYEVNLGTQIIYSDAAGDYVLLGD
LVDTKTHKNLTDARLSDLNKIDFASLPLANAIKVVKGNGARKIAVFSDPNCPYCKRLETTLQSVDNVTVYTFLYPVLSPD
STTKSKAIWCATDRAKSWEGWMLDHRAPSGAGNCDTSALDKNLALGRGMNVTGTPTIFLPDGRRLPGAVSADQLNQALAS
SK
>Mature_242_residues
MKKTIRIASLALAVTMATLGCTAQADQTTDKLKATLQARLGSDAPIKSVSKSPVAGLYEVNLGTQIIYSDAAGDYVLLGD
LVDTKTHKNLTDARLSDLNKIDFASLPLANAIKVVKGNGARKIAVFSDPNCPYCKRLETTLQSVDNVTVYTFLYPVLSPD
STTKSKAIWCATDRAKSWEGWMLDHRAPSGAGNCDTSALDKNLALGRGMNVTGTPTIFLPDGRRLPGAVSADQLNQALAS
SK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=247, Percent_Identity=28.7449392712551, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: NA

Molecular weight: Translated: 25763; Mature: 25763

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIRIASLALAVTMATLGCTAQADQTTDKLKATLQARLGSDAPIKSVSKSPVAGLYEV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEE
NLGTQIIYSDAAGDYVLLGDLVDTKTHKNLTDARLSDLNKIDFASLPLANAIKVVKGNGA
CCCEEEEEECCCCCEEEECCHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHEEEEECCCC
RKIAVFSDPNCPYCKRLETTLQSVDNVTVYTFLYPVLSPDSTTKSKAIWCATDRAKSWEG
EEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCC
WMLDHRAPSGAGNCDTSALDKNLALGRGMNVTGTPTIFLPDGRRLPGAVSADQLNQALAS
EEEECCCCCCCCCCCHHHHHCCHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHC
SK
CC
>Mature Secondary Structure
MKKTIRIASLALAVTMATLGCTAQADQTTDKLKATLQARLGSDAPIKSVSKSPVAGLYEV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEE
NLGTQIIYSDAAGDYVLLGDLVDTKTHKNLTDARLSDLNKIDFASLPLANAIKVVKGNGA
CCCEEEEEECCCCCEEEECCHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHEEEEECCCC
RKIAVFSDPNCPYCKRLETTLQSVDNVTVYTFLYPVLSPDSTTKSKAIWCATDRAKSWEG
EEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCC
WMLDHRAPSGAGNCDTSALDKNLALGRGMNVTGTPTIFLPDGRRLPGAVSADQLNQALAS
EEEECCCCCCCCCCCHHHHHCCHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHC
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-oxo-D 5-steroid; protein with reduced SH groups [C]

Specific reaction: 3-oxo-D 5-steroid = 3-oxo-D 4-steroid protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: Isomerases; Intramolecular Oxidoreductases; Transposing S-S Bonds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]