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The map label for this gene is ddpA [H]

Identifier: 116249437

GI number: 116249437

Start: 845066

End: 846652

Strand: Reverse

Name: ddpA [H]

Synonym: pRL120775

Alternate gene names: 116249437

Gene position: 846652-845066 (Counterclockwise)

Preceding gene: 116249438

Following gene: 116249436

Centisome position: 97.31

GC content: 61.69

Gene sequence:

>1587_bases
ATGCTGAGACAAGTACTGACAACGATCGCAATTGCCGGCGCCCTGACGACGGCGCAGCCCAGCTTCGCGGCCTCGCCGCC
CAACATGCTGGTGATCGGCACCAATCTCACCGGCATAAGGACGCTCGATCCGGCCCAGAACAATGCCCGCACGGTTTCCG
AGCTGATCTCGAACCTCTACGACAACCTCGTGCAACTGTCGCCGGACGATCTTAAAACGCTGAAGCCGATGCTCGCGACG
CAATGGAGCGTCTCGGCGGATGGCAAGATCATCACGCTGACATTACGCGACGACGCCGTCTTCCAGAGCGGCAACAAGGT
GACCGCCGAGGATGCTGCCTGGTCGATCCAGCGCGTCATCAAGATGGGCCAGGTCGGCTCCACGGACATCGCGCTCTGGG
GCTTCACACCTGAAAACGTCGAAAAGCTCGTTCGCGCAAAAGACGAACACACGCTCGAGATCGAGCTGCCGCAAGCGGTC
AATACCGATCTGGTGCTCTATTCGCTGGCGGGCTCGTCGATCGGCATCGTCGACAAGAAGACGGTTCTGTCGCACGAGGC
GAACGGCGATTTCGGCGGCGCCTGGCTTTCCGCCAATTCCGCCGGCAGTGGCCCATTCAGTCTGGCGCAGTGGCGGCCGA
ACGATGTCGCTATCTTCAATGCGCAGCCGAAATACTGGGGCGGCAAGCCGGCCATGGCGCGCGTCGTCGCTCGTCATATC
CCGGAATCCGGCAATCTCCGGCTTCAGCTCGAAGCCGGCGACGTCGATGTCGGCCAGTATGTGGCAAGCGGCGATCTCGA
TGCACTCGCTACCAAGAAGGACATGGTCATCGAGAATGTCCCGGGTCTCGGCTTCTACTATATCGCCCTCAATCAGAAAG
ACCCGGATCTGCAGAAGCCGAAGGTTCGCGAGGCCTTCCAGCATGCCTTCGACTGGAAAGCGATCTCCGGCAACATCATG
CGCCATACGGGCTTTCCCTGGCAGTCGATGATCCCGCGCGGCATGATCGGCGCTCCCGGCGAGGCGGAGGTGCGCTACGA
TTACGATCCCGCCAAGGCCAAGCAACTGCTGGCGGAGGCCGGATATCCCAATGGCCTGAAGAAGGTGCTCAATCCGTCGG
GAGCCCCGACCCTGCCCTTCGCCGAAGCGCTGCAGGCGAGTGCCCGCGCCGCCGGCATCGATCTCGATCTCGTGCCCGGC
GAGTTCACGCCCGCTTTCCGCGAGCGCAAATTCGAGGTGCTGCTCGGCAATTCCGGCGCCCGTCTGCCCGATCCCTTCGC
GGTCGCCACGCAATATGCCTTCAACCCCGACAATAGCGACGAGGCACGCCTCGGCAGCTATTACCTATGGCGCACGGGCA
TGAAGGTGGACGAGCTCAACACGCTCATCGACCAATCAATGAAGGAGCGCGACACGGAAAAGCGCACCGACATCTTCAAG
AAGATGGACGGCATCTATGCCGGCATGGCTTCGCCGCTGGTCATCTTCTTCCAGCGAACCGACCCCTATGTCATGCGCGC
CAACGTGAAGGGCTATCACGGGCATACGACATGGTCGACGCGCTGGCACGACGTGACCAAGGAGTAG

Upstream 100 bases:

>100_bases
GGCCGAAGGCGACATTCAAACTCATTCAGACCAGCCGGCCGTAAAGGCGGCCGGCTGATTTCGACACTATCCACAAACAA
CAGGATTGGGAGGTCTTGAG

Downstream 100 bases:

>100_bases
AAAGCCGTGGCAAGCGCCGATATCACATCGAAGGGGGGGAGCAGCCTGCCCTCCCCGGCCGGCGGGTTCGCCGAGGCGGC
CCCTCACCCGGCACTGAGCC

Product: putative substrate-binding component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MLRQVLTTIAIAGALTTAQPSFAASPPNMLVIGTNLTGIRTLDPAQNNARTVSELISNLYDNLVQLSPDDLKTLKPMLAT
QWSVSADGKIITLTLRDDAVFQSGNKVTAEDAAWSIQRVIKMGQVGSTDIALWGFTPENVEKLVRAKDEHTLEIELPQAV
NTDLVLYSLAGSSIGIVDKKTVLSHEANGDFGGAWLSANSAGSGPFSLAQWRPNDVAIFNAQPKYWGGKPAMARVVARHI
PESGNLRLQLEAGDVDVGQYVASGDLDALATKKDMVIENVPGLGFYYIALNQKDPDLQKPKVREAFQHAFDWKAISGNIM
RHTGFPWQSMIPRGMIGAPGEAEVRYDYDPAKAKQLLAEAGYPNGLKKVLNPSGAPTLPFAEALQASARAAGIDLDLVPG
EFTPAFRERKFEVLLGNSGARLPDPFAVATQYAFNPDNSDEARLGSYYLWRTGMKVDELNTLIDQSMKERDTEKRTDIFK
KMDGIYAGMASPLVIFFQRTDPYVMRANVKGYHGHTTWSTRWHDVTKE

Sequences:

>Translated_528_residues
MLRQVLTTIAIAGALTTAQPSFAASPPNMLVIGTNLTGIRTLDPAQNNARTVSELISNLYDNLVQLSPDDLKTLKPMLAT
QWSVSADGKIITLTLRDDAVFQSGNKVTAEDAAWSIQRVIKMGQVGSTDIALWGFTPENVEKLVRAKDEHTLEIELPQAV
NTDLVLYSLAGSSIGIVDKKTVLSHEANGDFGGAWLSANSAGSGPFSLAQWRPNDVAIFNAQPKYWGGKPAMARVVARHI
PESGNLRLQLEAGDVDVGQYVASGDLDALATKKDMVIENVPGLGFYYIALNQKDPDLQKPKVREAFQHAFDWKAISGNIM
RHTGFPWQSMIPRGMIGAPGEAEVRYDYDPAKAKQLLAEAGYPNGLKKVLNPSGAPTLPFAEALQASARAAGIDLDLVPG
EFTPAFRERKFEVLLGNSGARLPDPFAVATQYAFNPDNSDEARLGSYYLWRTGMKVDELNTLIDQSMKERDTEKRTDIFK
KMDGIYAGMASPLVIFFQRTDPYVMRANVKGYHGHTTWSTRWHDVTKE
>Mature_528_residues
MLRQVLTTIAIAGALTTAQPSFAASPPNMLVIGTNLTGIRTLDPAQNNARTVSELISNLYDNLVQLSPDDLKTLKPMLAT
QWSVSADGKIITLTLRDDAVFQSGNKVTAEDAAWSIQRVIKMGQVGSTDIALWGFTPENVEKLVRAKDEHTLEIELPQAV
NTDLVLYSLAGSSIGIVDKKTVLSHEANGDFGGAWLSANSAGSGPFSLAQWRPNDVAIFNAQPKYWGGKPAMARVVARHI
PESGNLRLQLEAGDVDVGQYVASGDLDALATKKDMVIENVPGLGFYYIALNQKDPDLQKPKVREAFQHAFDWKAISGNIM
RHTGFPWQSMIPRGMIGAPGEAEVRYDYDPAKAKQLLAEAGYPNGLKKVLNPSGAPTLPFAEALQASARAAGIDLDLVPG
EFTPAFRERKFEVLLGNSGARLPDPFAVATQYAFNPDNSDEARLGSYYLWRTGMKVDELNTLIDQSMKERDTEKRTDIFK
KMDGIYAGMASPLVIFFQRTDPYVMRANVKGYHGHTTWSTRWHDVTKE

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=522, Percent_Identity=29.1187739463602, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787551, Length=392, Percent_Identity=26.0204081632653, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789966, Length=480, Percent_Identity=26.25, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787052, Length=369, Percent_Identity=25.4742547425474, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789887, Length=405, Percent_Identity=27.1604938271605, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787495, Length=563, Percent_Identity=23.4458259325044, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57843; Mature: 57843

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQVLTTIAIAGALTTAQPSFAASPPNMLVIGTNLTGIRTLDPAQNNARTVSELISNLY
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHH
DNLVQLSPDDLKTLKPMLATQWSVSADGKIITLTLRDDAVFQSGNKVTAEDAAWSIQRVI
HHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHCCCCEEEHHHHHHHHHHHH
KMGQVGSTDIALWGFTPENVEKLVRAKDEHTLEIELPQAVNTDLVLYSLAGSSIGIVDKK
HHCCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEECH
TVLSHEANGDFGGAWLSANSAGSGPFSLAQWRPNDVAIFNAQPKYWGGKPAMARVVARHI
HHHCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHC
PESGNLRLQLEAGDVDVGQYVASGDLDALATKKDMVIENVPGLGFYYIALNQKDPDLQKP
CCCCCEEEEEECCCCCHHHEEECCCCHHHHCCCCHHEECCCCCEEEEEEECCCCCCCCCC
KVREAFQHAFDWKAISGNIMRHTGFPWQSMIPRGMIGAPGEAEVRYDYDPAKAKQLLAEA
HHHHHHHHHCCCEECCCCEEECCCCCHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
GYPNGLKKVLNPSGAPTLPFAEALQASARAAGIDLDLVPGEFTPAFRERKFEVLLGNSGA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHCCEEEEEECCCCC
RLPDPFAVATQYAFNPDNSDEARLGSYYLWRTGMKVDELNTLIDQSMKERDTEKRTDIFK
CCCCCHHHHEEEEECCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KMDGIYAGMASPLVIFFQRTDPYVMRANVKGYHGHTTWSTRWHDVTKE
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRQVLTTIAIAGALTTAQPSFAASPPNMLVIGTNLTGIRTLDPAQNNARTVSELISNLY
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHH
DNLVQLSPDDLKTLKPMLATQWSVSADGKIITLTLRDDAVFQSGNKVTAEDAAWSIQRVI
HHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHCCCCEEEHHHHHHHHHHHH
KMGQVGSTDIALWGFTPENVEKLVRAKDEHTLEIELPQAVNTDLVLYSLAGSSIGIVDKK
HHCCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEECH
TVLSHEANGDFGGAWLSANSAGSGPFSLAQWRPNDVAIFNAQPKYWGGKPAMARVVARHI
HHHCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHC
PESGNLRLQLEAGDVDVGQYVASGDLDALATKKDMVIENVPGLGFYYIALNQKDPDLQKP
CCCCCEEEEEECCCCCHHHEEECCCCHHHHCCCCHHEECCCCCEEEEEEECCCCCCCCCC
KVREAFQHAFDWKAISGNIMRHTGFPWQSMIPRGMIGAPGEAEVRYDYDPAKAKQLLAEA
HHHHHHHHHCCCEECCCCEEECCCCCHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
GYPNGLKKVLNPSGAPTLPFAEALQASARAAGIDLDLVPGEFTPAFRERKFEVLLGNSGA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHCCEEEEEECCCCC
RLPDPFAVATQYAFNPDNSDEARLGSYYLWRTGMKVDELNTLIDQSMKERDTEKRTDIFK
CCCCCHHHHEEEEECCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KMDGIYAGMASPLVIFFQRTDPYVMRANVKGYHGHTTWSTRWHDVTKE
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]