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The map label for this gene is dppB [H]

Identifier: 116249436

GI number: 116249436

Start: 843962

End: 845059

Strand: Reverse

Name: dppB [H]

Synonym: pRL120774

Alternate gene names: 116249436

Gene position: 845059-843962 (Counterclockwise)

Preceding gene: 116249437

Following gene: 116249435

Centisome position: 97.13

GC content: 62.75

Gene sequence:

>1098_bases
GTGGCAAGCGCCGATATCACATCGAAGGGGGGGAGCAGCCTGCCCTCCCCGGCCGGCGGGTTCGCCGAGGCGGCCCCTCA
CCCGGCACTGAGCCTGCTGCGGCGCTTGGCGGGACGCGTCGTGGCCGTCGTGACGACGCTGCTCGGCCTGCTCTTCCTGA
CCTTCTCGATGGGCCGCCTGCTGCCCGCTGACCCGGTGCTCGCCATCACCGGGGCGGAAGTCAGCAAGGAGGTTTACGAT
CGCGTCTATAACGAGCTGGGTCTTGGGCAGCCGATCTGGATGCAGTTCCTGTCCTACGTCGGCAAGATCGCCACAGGCGA
TCTCGGCATGTCGGCGACGACGGGCCAGCCGATCCTCACCGATCTGATGGCGATCTTTCCCGCGACGATCGAACTTGCGA
TCATCGCCATGATCATCGGAGCGATCGTCGGCATTCCCTTAGGGATCACCGCTGCGGTCAGGCGCGGAACCATTATCGAC
CACATCGCACGGATCGTCGCCCTTGCCGGCCACTCGATCCCGATCTTCTGGACCGGGCTGATGGCGCTCTTCGTCTTTTA
TGCGAAGCTGAAGCTCGTCGGCGCCTCGGGCCGGATCGATGTCTTCTATGAAGGCCTCGTCACGCCGATGACGGGCTTTC
TCCTGATCGACGCGGCGATTCAGGGCCAATGGGACGTGTTTTACAACGCCCTTGGCCACATCATCCTTCCGGCGGCAATC
CTCGGCTATTATTCCGTCGCCTATATCAGCCGCATGTCGCGGAGCTTCATGCTGGAGCAACTGAGCCAGGAATACATCAT
CACGGCGCGGGCCAAGGGGCTCGGCACCCGCAAGGTGGTCTGGCGCCACGCATTCAAGAACATCCGCGTGCAGCTTTTGA
CGATCATGGCGCTGACCTTCGGCGGTCTGCTCGAAGGCGCGGTGCTGATCGAGACCGTCTTCGGGTGGCCGGGGCTCGGT
CAGTACCTGACCCGGGGGCTGCAGATGAACGACATGAACGTGGTCATGGGTTCGGTCCTGACGATCGGCGCCGTCTTCCT
GACGATCAACATCCTGTCGGACTTCCTTTATCGCATTCTTGATCCGAGGACACGGTGA

Upstream 100 bases:

>100_bases
GCGAACCGACCCCTATGTCATGCGCGCCAACGTGAAGGGCTATCACGGGCATACGACATGGTCGACGCGCTGGCACGACG
TGACCAAGGAGTAGAAAGCC

Downstream 100 bases:

>100_bases
CGCCATGACGATCTCCTCTGAGCACGCAAACAGCGTCAACATCGGCGGCCTTCGCAACTGGCTGCTCGCACCGGAGCCTC
GAGGCTGGTTCCAGTCATCG

Product: putative permease component of ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MASADITSKGGSSLPSPAGGFAEAAPHPALSLLRRLAGRVVAVVTTLLGLLFLTFSMGRLLPADPVLAITGAEVSKEVYD
RVYNELGLGQPIWMQFLSYVGKIATGDLGMSATTGQPILTDLMAIFPATIELAIIAMIIGAIVGIPLGITAAVRRGTIID
HIARIVALAGHSIPIFWTGLMALFVFYAKLKLVGASGRIDVFYEGLVTPMTGFLLIDAAIQGQWDVFYNALGHIILPAAI
LGYYSVAYISRMSRSFMLEQLSQEYIITARAKGLGTRKVVWRHAFKNIRVQLLTIMALTFGGLLEGAVLIETVFGWPGLG
QYLTRGLQMNDMNVVMGSVLTIGAVFLTINILSDFLYRILDPRTR

Sequences:

>Translated_365_residues
MASADITSKGGSSLPSPAGGFAEAAPHPALSLLRRLAGRVVAVVTTLLGLLFLTFSMGRLLPADPVLAITGAEVSKEVYD
RVYNELGLGQPIWMQFLSYVGKIATGDLGMSATTGQPILTDLMAIFPATIELAIIAMIIGAIVGIPLGITAAVRRGTIID
HIARIVALAGHSIPIFWTGLMALFVFYAKLKLVGASGRIDVFYEGLVTPMTGFLLIDAAIQGQWDVFYNALGHIILPAAI
LGYYSVAYISRMSRSFMLEQLSQEYIITARAKGLGTRKVVWRHAFKNIRVQLLTIMALTFGGLLEGAVLIETVFGWPGLG
QYLTRGLQMNDMNVVMGSVLTIGAVFLTINILSDFLYRILDPRTR
>Mature_364_residues
ASADITSKGGSSLPSPAGGFAEAAPHPALSLLRRLAGRVVAVVTTLLGLLFLTFSMGRLLPADPVLAITGAEVSKEVYDR
VYNELGLGQPIWMQFLSYVGKIATGDLGMSATTGQPILTDLMAIFPATIELAIIAMIIGAIVGIPLGITAAVRRGTIIDH
IARIVALAGHSIPIFWTGLMALFVFYAKLKLVGASGRIDVFYEGLVTPMTGFLLIDAAIQGQWDVFYNALGHIILPAAIL
GYYSVAYISRMSRSFMLEQLSQEYIITARAKGLGTRKVVWRHAFKNIRVQLLTIMALTFGGLLEGAVLIETVFGWPGLGQ
YLTRGLQMNDMNVVMGSVLTIGAVFLTINILSDFLYRILDPRTR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=42.8571428571429, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1787761, Length=333, Percent_Identity=40.8408408408408, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787053, Length=334, Percent_Identity=30.8383233532934, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=32.8519855595668, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789888, Length=337, Percent_Identity=28.7833827893175, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=29.7619047619048, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788504, Length=296, Percent_Identity=26.6891891891892, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39336; Mature: 39205

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASADITSKGGSSLPSPAGGFAEAAPHPALSLLRRLAGRVVAVVTTLLGLLFLTFSMGRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPADPVLAITGAEVSKEVYDRVYNELGLGQPIWMQFLSYVGKIATGDLGMSATTGQPILT
CCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
DLMAIFPATIELAIIAMIIGAIVGIPLGITAAVRRGTIIDHIARIVALAGHSIPIFWTGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHH
MALFVFYAKLKLVGASGRIDVFYEGLVTPMTGFLLIDAAIQGQWDVFYNALGHIILPAAI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LGYYSVAYISRMSRSFMLEQLSQEYIITARAKGLGTRKVVWRHAFKNIRVQLLTIMALTF
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GGLLEGAVLIETVFGWPGLGQYLTRGLQMNDMNVVMGSVLTIGAVFLTINILSDFLYRIL
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPRTR
CCCCC
>Mature Secondary Structure 
ASADITSKGGSSLPSPAGGFAEAAPHPALSLLRRLAGRVVAVVTTLLGLLFLTFSMGRL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPADPVLAITGAEVSKEVYDRVYNELGLGQPIWMQFLSYVGKIATGDLGMSATTGQPILT
CCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
DLMAIFPATIELAIIAMIIGAIVGIPLGITAAVRRGTIIDHIARIVALAGHSIPIFWTGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHH
MALFVFYAKLKLVGASGRIDVFYEGLVTPMTGFLLIDAAIQGQWDVFYNALGHIILPAAI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LGYYSVAYISRMSRSFMLEQLSQEYIITARAKGLGTRKVVWRHAFKNIRVQLLTIMALTF
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GGLLEGAVLIETVFGWPGLGQYLTRGLQMNDMNVVMGSVLTIGAVFLTINILSDFLYRIL
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPRTR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]