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The map label for this gene is dppA [C]

Identifier: 116248994

GI number: 116248994

Start: 349057

End: 350655

Strand: Direct

Name: dppA [C]

Synonym: pRL120326

Alternate gene names: 116248994

Gene position: 349057-350655 (Clockwise)

Preceding gene: 116248993

Following gene: 116248995

Centisome position: 40.12

GC content: 60.41

Gene sequence:

>1599_bases
ATGAAAAGACTGTCTAGACTATCCGTTATTGCGCTTGGCGCCCTGCTGTCGACGGCTGCCGTTCCGGCTCTTGTCGTTTC
GGGCGTTGCAACCCAGGCTCAGGCAGCCACGCTGTCGGGCGGCTTCGATGTCGGCCCCGGAGGCTTCCAGGGCAACTTCA
ATCCGCTCGCCGCGACCGCCGGCTTCACCTGGCTCAGCGTCTACTACGAACCGCTGATCACCTATGACGAGAAGCTGCAG
AAGGTCGTCGGCGCGCTGGCAAGCTCCTACGAGGTCAGCTCCGACCAGATGACCTACACGTTCAAGCTGACGGACGCCAA
ATGGCATGACGGCAAACCGTTCACCGCCAAGGACGCGAAGTTCACCATGGGCCTTGCTATGGATGCGAAAACCGGCTCGG
TGCTCGCTGCCCGGCTGAAGGGCATATCGTCCGTCGAGACGCCGGACGATCGCACTGTTATCATCAAGCTTAGCGCGCCG
AGCAGCAGTTTTCCCGACACGATGACCAAGGTGATGATGCTGCCCGAGCATGCGCTCTCCTCGATTCCGGCCGACCAGCT
GGCGAAGAACACCTGGTGGTCCACAGCTCCGATCGGCACCGGTCCGTTCAAATTCACCAAATACGTCTCGGATCAATATG
TCGAACTTGCCGCAAACACCGATTATCGCGGTGGCAAACCCGCACTGGAACGCGTCATCAATCGCTATTTCGCCAACCCG
GCCGCAGCGATCGCGGCGCTGAGATCCGGCGAAATTCAGTTCACCTATGTCGATTCCAACGACGTGCCGACCTTCAAGGA
CAACAAGGACTTCCAGGTCATCGAAGGCAACTCTTTCGTCGTCAATTATCTCGGCTTCAACCACGATTCGCCGCTCTGGA
AGGACGCGCGCGTCCGCCAGGCGGTGATGTACGCGATCAATCGCGATGCCATCATCCAGAGCCTCTATGGCGGCGCGGCC
AAGCCTGCCAATTGCGCCTATGTCGCCGAACAGCTGATCCCCCCTGATATCGACAGCTATGCCTATGATCCCGAGAAGGC
CAAGAAGCTTTTGACGGATGCCGGCTGGGACCAGATCAATGGCGGCAAGCCGATCACCCTTCTGACCTATTACACCACAC
CGCTGGCGACCAATGTGCTTGCCGCAGTCCAGGCGATGCTGGCCCAGGTCGGCATCAACATCGTCCCGCGTGCCGTCGAT
GCGCCGACCTATAACAGCATCGTGCTCAATGCGACGCCGGACATTGCCCAGTTCCAATTGGTTTATGCCGGGCTGCAGAA
CGGGCCGGATGCCGGAAGCATCAATGTCGGCCTTAACGAGAAGCAGATCCCTCCGGCCGGACCGAATGTCGCCAGGGTTC
GCATGCCTGACCTCACCAAGGCGCTCGATAGTGCCTTGGCCGAGCCTGACAGCACCAAGCGGGATGCCGCCTACCAGGAC
GTCTGCAAGGTGATGAACACCAACCTGCCCTGGGCGACCCTCTGGGTGGCGAACCGCTACGGCATCGTCTCGACCAAGGT
GAAGGATTTCGTCTGGACGCCGGCGCCGGGCGGCGGCCCCTACCAGGCCAACCCGCAGAAATGGTCGATCGCCGAATAG

Upstream 100 bases:

>100_bases
AAAGATCTGGAGGAGGCGCGCAGACGCCTGGATCGTCACTACGAGGGCATTGCCCGGGTGATTGCCAACAACAAGACAAG
TTCAAACGTGGGAGGAACAC

Downstream 100 bases:

>100_bases
GCTCTTTCCGGGAAAGCCTTGAGGGTGGCCTCGGCCACCCTGACAAGACGGATGAACCATGCTCCAATACAGTCTCAGAC
GCCTGGTCATAGGAATAGGC

Product: putative substrate binding component of ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MKRLSRLSVIALGALLSTAAVPALVVSGVATQAQAATLSGGFDVGPGGFQGNFNPLAATAGFTWLSVYYEPLITYDEKLQ
KVVGALASSYEVSSDQMTYTFKLTDAKWHDGKPFTAKDAKFTMGLAMDAKTGSVLAARLKGISSVETPDDRTVIIKLSAP
SSSFPDTMTKVMMLPEHALSSIPADQLAKNTWWSTAPIGTGPFKFTKYVSDQYVELAANTDYRGGKPALERVINRYFANP
AAAIAALRSGEIQFTYVDSNDVPTFKDNKDFQVIEGNSFVVNYLGFNHDSPLWKDARVRQAVMYAINRDAIIQSLYGGAA
KPANCAYVAEQLIPPDIDSYAYDPEKAKKLLTDAGWDQINGGKPITLLTYYTTPLATNVLAAVQAMLAQVGINIVPRAVD
APTYNSIVLNATPDIAQFQLVYAGLQNGPDAGSINVGLNEKQIPPAGPNVARVRMPDLTKALDSALAEPDSTKRDAAYQD
VCKVMNTNLPWATLWVANRYGIVSTKVKDFVWTPAPGGGPYQANPQKWSIAE

Sequences:

>Translated_532_residues
MKRLSRLSVIALGALLSTAAVPALVVSGVATQAQAATLSGGFDVGPGGFQGNFNPLAATAGFTWLSVYYEPLITYDEKLQ
KVVGALASSYEVSSDQMTYTFKLTDAKWHDGKPFTAKDAKFTMGLAMDAKTGSVLAARLKGISSVETPDDRTVIIKLSAP
SSSFPDTMTKVMMLPEHALSSIPADQLAKNTWWSTAPIGTGPFKFTKYVSDQYVELAANTDYRGGKPALERVINRYFANP
AAAIAALRSGEIQFTYVDSNDVPTFKDNKDFQVIEGNSFVVNYLGFNHDSPLWKDARVRQAVMYAINRDAIIQSLYGGAA
KPANCAYVAEQLIPPDIDSYAYDPEKAKKLLTDAGWDQINGGKPITLLTYYTTPLATNVLAAVQAMLAQVGINIVPRAVD
APTYNSIVLNATPDIAQFQLVYAGLQNGPDAGSINVGLNEKQIPPAGPNVARVRMPDLTKALDSALAEPDSTKRDAAYQD
VCKVMNTNLPWATLWVANRYGIVSTKVKDFVWTPAPGGGPYQANPQKWSIAE
>Mature_532_residues
MKRLSRLSVIALGALLSTAAVPALVVSGVATQAQAATLSGGFDVGPGGFQGNFNPLAATAGFTWLSVYYEPLITYDEKLQ
KVVGALASSYEVSSDQMTYTFKLTDAKWHDGKPFTAKDAKFTMGLAMDAKTGSVLAARLKGISSVETPDDRTVIIKLSAP
SSSFPDTMTKVMMLPEHALSSIPADQLAKNTWWSTAPIGTGPFKFTKYVSDQYVELAANTDYRGGKPALERVINRYFANP
AAAIAALRSGEIQFTYVDSNDVPTFKDNKDFQVIEGNSFVVNYLGFNHDSPLWKDARVRQAVMYAINRDAIIQSLYGGAA
KPANCAYVAEQLIPPDIDSYAYDPEKAKKLLTDAGWDQINGGKPITLLTYYTTPLATNVLAAVQAMLAQVGINIVPRAVD
APTYNSIVLNATPDIAQFQLVYAGLQNGPDAGSINVGLNEKQIPPAGPNVARVRMPDLTKALDSALAEPDSTKRDAAYQD
VCKVMNTNLPWATLWVANRYGIVSTKVKDFVWTPAPGGGPYQANPQKWSIAE

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=538, Percent_Identity=28.6245353159851, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1787052, Length=461, Percent_Identity=27.5488069414317, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787762, Length=516, Percent_Identity=25.5813953488372, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789887, Length=450, Percent_Identity=25.1111111111111, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787551, Length=545, Percent_Identity=24.5871559633028, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789397, Length=458, Percent_Identity=23.7991266375546, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787495, Length=430, Percent_Identity=25.1162790697674, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082063, Length=358, Percent_Identity=23.463687150838, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57335; Mature: 57335

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLSRLSVIALGALLSTAAVPALVVSGVATQAQAATLSGGFDVGPGGFQGNFNPLAATA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHC
GFTWLSVYYEPLITYDEKLQKVVGALASSYEVSSDQMTYTFKLTDAKWHDGKPFTAKDAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
FTMGLAMDAKTGSVLAARLKGISSVETPDDRTVIIKLSAPSSSFPDTMTKVMMLPEHALS
EEEEEEECCCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHHHH
SIPADQLAKNTWWSTAPIGTGPFKFTKYVSDQYVELAANTDYRGGKPALERVINRYFANP
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCH
AAAIAALRSGEIQFTYVDSNDVPTFKDNKDFQVIEGNSFVVNYLGFNHDSPLWKDARVRQ
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHH
AVMYAINRDAIIQSLYGGAAKPANCAYVAEQLIPPDIDSYAYDPEKAKKLLTDAGWDQIN
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GGKPITLLTYYTTPLATNVLAAVQAMLAQVGINIVPRAVDAPTYNSIVLNATPDIAQFQL
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEECCCCHHHHHH
VYAGLQNGPDAGSINVGLNEKQIPPAGPNVARVRMPDLTKALDSALAEPDSTKRDAAYQD
HHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHH
VCKVMNTNLPWATLWVANRYGIVSTKVKDFVWTPAPGGGPYQANPQKWSIAE
HHHHHCCCCCEEEEEEECCCCEEEEEHHHEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRLSRLSVIALGALLSTAAVPALVVSGVATQAQAATLSGGFDVGPGGFQGNFNPLAATA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHC
GFTWLSVYYEPLITYDEKLQKVVGALASSYEVSSDQMTYTFKLTDAKWHDGKPFTAKDAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
FTMGLAMDAKTGSVLAARLKGISSVETPDDRTVIIKLSAPSSSFPDTMTKVMMLPEHALS
EEEEEEECCCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHHHH
SIPADQLAKNTWWSTAPIGTGPFKFTKYVSDQYVELAANTDYRGGKPALERVINRYFANP
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCH
AAAIAALRSGEIQFTYVDSNDVPTFKDNKDFQVIEGNSFVVNYLGFNHDSPLWKDARVRQ
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHH
AVMYAINRDAIIQSLYGGAAKPANCAYVAEQLIPPDIDSYAYDPEKAKKLLTDAGWDQIN
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GGKPITLLTYYTTPLATNVLAAVQAMLAQVGINIVPRAVDAPTYNSIVLNATPDIAQFQL
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEECCCCHHHHHH
VYAGLQNGPDAGSINVGLNEKQIPPAGPNVARVRMPDLTKALDSALAEPDSTKRDAAYQD
HHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHH
VCKVMNTNLPWATLWVANRYGIVSTKVKDFVWTPAPGGGPYQANPQKWSIAE
HHHHHCCCCCEEEEEEECCCCEEEEEHHHEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA