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The map label for this gene is uxuR [H]

Identifier: 116248993

GI number: 116248993

Start: 348330

End: 349073

Strand: Direct

Name: uxuR [H]

Synonym: pRL120325

Alternate gene names: 116248993

Gene position: 348330-349073 (Clockwise)

Preceding gene: 116248992

Following gene: 116248994

Centisome position: 40.04

GC content: 59.81

Gene sequence:

>744_bases
ATGACATTGAAATCGATGAAGCCGCTGACGCGTGCCCCGCTGTTGCATGTCTCCGTGCAGGAAAGTCTGCGCGCCTATAT
CGACGACAATGGCCTTGCGCCCGGAACCCTGCTTCCGGCGGAAGGAGAACTCGCCACCCAGCTAGGTGTCAGCCGCAATT
CGCTGAGGGAAGGCATAAAGGCGTTGGAATCGCTCGGTGTGCTGGAGACGCGGCGCGGCGTCGGCATCTTCGTGAAGGCC
TTTTCCTTCGAGCCGCTTCTCGACAACCTCGCTTACGGCCTCGGCGGCGCCCTGCGGCAGATCGAGGAGGTCCTCGAAAT
CCGGCGTACACTGGAAGTGGGATTGATCGGCAAGACGATCGACGTGATTGGCGAGGAGGACATCGCCGAGCTGCGCGCCA
CCGTCAATCGGATGCGCGCGCATGCCGAGCGGGGCGAAACCTTTGCGGAAGACGACCAGTTGTTCCACCGGCTGCTGTTT
CGCTGCCAGGACAATGAAACGCTGGTGCGGCTGATCGATGTCTTCTGGCTCGCCTTCTACAAGGCGTCGGATTTCGTCAA
TCTTGAAAATGCCGATCCGATGGCGACGTGGCGCGACCATGCCGCGATCGTCGATGCGATCGAGGCAAAAGATCTGGAGG
AGGCGCGCAGACGCCTGGATCGTCACTACGAGGGCATTGCCCGGGTGATTGCCAACAACAAGACAAGTTCAAACGTGGGA
GGAACACATGAAAAGACTGTCTAG

Upstream 100 bases:

>100_bases
GCGGAGGGGCCAGCCATTCCAAGCCTGACCATTTGACAGATATCCTACAAGTGGATATGTAATATCCATCTTATTGGCGA
TGCGGGAAAGTGACCGGGGC

Downstream 100 bases:

>100_bases
ACTATCCGTTATTGCGCTTGGCGCCCTGCTGTCGACGGCTGCCGTTCCGGCTCTTGTCGTTTCGGGCGTTGCAACCCAGG
CTCAGGCAGCCACGCTGTCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTLKSMKPLTRAPLLHVSVQESLRAYIDDNGLAPGTLLPAEGELATQLGVSRNSLREGIKALESLGVLETRRGVGIFVKA
FSFEPLLDNLAYGLGGALRQIEEVLEIRRTLEVGLIGKTIDVIGEEDIAELRATVNRMRAHAERGETFAEDDQLFHRLLF
RCQDNETLVRLIDVFWLAFYKASDFVNLENADPMATWRDHAAIVDAIEAKDLEEARRRLDRHYEGIARVIANNKTSSNVG
GTHEKTV

Sequences:

>Translated_247_residues
MTLKSMKPLTRAPLLHVSVQESLRAYIDDNGLAPGTLLPAEGELATQLGVSRNSLREGIKALESLGVLETRRGVGIFVKA
FSFEPLLDNLAYGLGGALRQIEEVLEIRRTLEVGLIGKTIDVIGEEDIAELRATVNRMRAHAERGETFAEDDQLFHRLLF
RCQDNETLVRLIDVFWLAFYKASDFVNLENADPMATWRDHAAIVDAIEAKDLEEARRRLDRHYEGIARVIANNKTSSNVG
GTHEKTV
>Mature_246_residues
TLKSMKPLTRAPLLHVSVQESLRAYIDDNGLAPGTLLPAEGELATQLGVSRNSLREGIKALESLGVLETRRGVGIFVKAF
SFEPLLDNLAYGLGGALRQIEEVLEIRRTLEVGLIGKTIDVIGEEDIAELRATVNRMRAHAERGETFAEDDQLFHRLLFR
CQDNETLVRLIDVFWLAFYKASDFVNLENADPMATWRDHAAIVDAIEAKDLEEARRRLDRHYEGIARVIANNKTSSNVGG
THEKTV

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=61, Percent_Identity=55.7377049180328, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786303, Length=102, Percent_Identity=39.2156862745098, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27579; Mature: 27448

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKSMKPLTRAPLLHVSVQESLRAYIDDNGLAPGTLLPAEGELATQLGVSRNSLREGIK
CCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHH
ALESLGVLETRRGVGIFVKAFSFEPLLDNLAYGLGGALRQIEEVLEIRRTLEVGLIGKTI
HHHHHCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVIGEEDIAELRATVNRMRAHAERGETFAEDDQLFHRLLFRCQDNETLVRLIDVFWLAFY
HHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KASDFVNLENADPMATWRDHAAIVDAIEAKDLEEARRRLDRHYEGIARVIANNKTSSNVG
HHCCCEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GTHEKTV
CCCCCCC
>Mature Secondary Structure 
TLKSMKPLTRAPLLHVSVQESLRAYIDDNGLAPGTLLPAEGELATQLGVSRNSLREGIK
CCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHH
ALESLGVLETRRGVGIFVKAFSFEPLLDNLAYGLGGALRQIEEVLEIRRTLEVGLIGKTI
HHHHHCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVIGEEDIAELRATVNRMRAHAERGETFAEDDQLFHRLLFRCQDNETLVRLIDVFWLAFY
HHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KASDFVNLENADPMATWRDHAAIVDAIEAKDLEEARRRLDRHYEGIARVIANNKTSSNVG
HHCCCEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GTHEKTV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]