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The map label for this gene is mcpA [H]

Identifier: 116248981

GI number: 116248981

Start: 330022

End: 331899

Strand: Reverse

Name: mcpA [H]

Synonym: pRL120312

Alternate gene names: 116248981

Gene position: 331899-330022 (Counterclockwise)

Preceding gene: 116248983

Following gene: 116248980

Centisome position: 38.15

GC content: 58.79

Gene sequence:

>1878_bases
ATGAAACGCCCGAGTATCAAGCAAGCCCTGATCTTAAAGCTGTCGATCATCACTCTGTTCATGGTTAGCCTGTCCTATGT
CTCGCTGAGCACGATTTCGACGCTTCGTGCCAATACCGAGCAGATCGGGACCTTCTGGATGCAGCGGCTTGTGACGGCTC
GCGAGATCAAGGATGACTTCCTCGACCTGAAACTGGTCTATGCCCAGTACCTCCTGGAGGATACGGCGGAGGAGCGGATG
GTTGGACAACAAAAAATCGATGCCGCCGGCGCCGCGGTCGAGAAAGTCGTCACCGAATACGAAAGGGGTGTCCGCACCGA
GCGTGGACGCGAACTGATCAACCAGATGAAGCCGGAACTCGCCAAATATCGCGCGCTGGCAGAGCAAATGATCGCGCTTG
AAAATGACGGGAAGACGCCTGAAGCAATCCGCCTCTTCAAGGAAAATATGGAACCACAAGCGGAACTGGTCAACAAGGCG
GTGGCGGACCTGGTCGCTTTCATTCTCGGCCAGGCCGAAGGTTTTGTGGCCGCGAGCGGTGCTTCCGCGCAATCCGCTTT
CATGCTGACGGCCACGATCGCAGTGCTGGCAGTGCTTCTTGCCGTAGCCGGAATCTTATTTGCGATATCGGGCATCGCCA
ACCCAATCCGAAGCATCGCCTCAGCCATGAGGCGCTTGTCGGATGGCGATCTTGACAGCGATATTCCCTATGCCGGTCGC
GCCGACGAAGTCGGCGAAATGGCCGGCGCGGTTGAAATCTTTCGTCAGAATGCCCTCAACGTCGTCAGGCTCGAGAAGGA
AGCCGCCGAATCCCGCAGCGAGAGCGAGGCAGCGCGCGCCGCAGCCCAGCAGCGCGCCGAACGCGAGGCGGAACAATTGC
GCTTCGCGACCACGACATTGGGCGAAGGCCTCCGGCGGCTTGCATCAGGTGACATATCCTTCCAGCTTTCGGAGCAATTT
GCGGCCGAATACGAAGCCTTGCGCGAAGACTTTAACGCTTCGCTCCGGCAATTGGGCGCGACGATCGGCGCCGTGCTGCA
GACGGTGTACAGCATCGATAATGGTACCGGTGAGATTGCATCTGCCGCGCAGGATCTTTCCAAGCGTACCGAACAACAAG
CCGCCTCTCTCGAGGAGACGGCCGCAGCCCTGGAAGAGATCACGTCGAATGTGACGATGGCGACCAAACGCACCGACGAG
GCGCGCAATGTCGCCAAAGAAGCCGATATCAGTGCTCAGCGGTCGGCAGCGGTCGTCTCGCAGGCGGAAGGGGCCATGCG
ACGCATCGAGGACAGTTCACAGCAGATTTCGAACATCATCGGTGCAATTGATGAAATCGCCTTTCAGACGAACCTCCTGG
CGCTGAATGCCGGCGTTGAGGCTGCCCGTGCGGGTGAGGCGGGCAAGGGTTTTGCCGTTGTCGCCCAGGAAGTCCGTGAG
CTCGCCCAGCGTGCCGCTCAAGCGGCCAAGGAAATCAAAGGCTTTATTCAAAAGTCATCAGCAGATGTGGAAAATGGCGT
GAAACTGGTTCTTGAAACCGGAACCTCGCTCAAGTCGATCGGTGAGTACGTTGTCCATATCAACCAACTCATGGATGCGA
TTGCCACATCGGCGCGCGAGCAGTCGACTGGACTTGCCGAGATCAACACGGCCGTCAATCAAATGGACCAGGCGACCCAG
CAAAACGCGGCAATGGTCGAGCAGTCGACGGCTGCCGTTGCCTCATTGTCCTCCGAGGCGGGCCGCCTGCGGGATCTGGT
CAACCAGTTTCAATTGGACGGCGACAAAAGTGCCGCGGACGGGCAGCGCAGCGGGCGGGCCTTTGAAGGCAATAGGCCAA
TCCACTTGGTCGCTTCGCGGCGCGTGACGCAAAGATGA

Upstream 100 bases:

>100_bases
GCGGGACCATTGTTTAGTTAATACTAAATTATGGAATCCGGTGCGAGATCTTACATCAGCCGGCACGCCGCTCGTCCCAG
CTATCTTCGAGGAGACCCGC

Downstream 100 bases:

>100_bases
CGCGCGGCTGACGTCAGGTAAGATACCGAAAGACATTGACCTGGCGCCTGGGCGATCATCGGCTCGATCCCTCCAAAGCA
GTTGTCCCGCATCACTCGTC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MKRPSIKQALILKLSIITLFMVSLSYVSLSTISTLRANTEQIGTFWMQRLVTAREIKDDFLDLKLVYAQYLLEDTAEERM
VGQQKIDAAGAAVEKVVTEYERGVRTERGRELINQMKPELAKYRALAEQMIALENDGKTPEAIRLFKENMEPQAELVNKA
VADLVAFILGQAEGFVAASGASAQSAFMLTATIAVLAVLLAVAGILFAISGIANPIRSIASAMRRLSDGDLDSDIPYAGR
ADEVGEMAGAVEIFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGEGLRRLASGDISFQLSEQF
AAEYEALREDFNASLRQLGATIGAVLQTVYSIDNGTGEIASAAQDLSKRTEQQAASLEETAAALEEITSNVTMATKRTDE
ARNVAKEADISAQRSAAVVSQAEGAMRRIEDSSQQISNIIGAIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGFIQKSSADVENGVKLVLETGTSLKSIGEYVVHINQLMDAIATSAREQSTGLAEINTAVNQMDQATQ
QNAAMVEQSTAAVASLSSEAGRLRDLVNQFQLDGDKSAADGQRSGRAFEGNRPIHLVASRRVTQR

Sequences:

>Translated_625_residues
MKRPSIKQALILKLSIITLFMVSLSYVSLSTISTLRANTEQIGTFWMQRLVTAREIKDDFLDLKLVYAQYLLEDTAEERM
VGQQKIDAAGAAVEKVVTEYERGVRTERGRELINQMKPELAKYRALAEQMIALENDGKTPEAIRLFKENMEPQAELVNKA
VADLVAFILGQAEGFVAASGASAQSAFMLTATIAVLAVLLAVAGILFAISGIANPIRSIASAMRRLSDGDLDSDIPYAGR
ADEVGEMAGAVEIFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGEGLRRLASGDISFQLSEQF
AAEYEALREDFNASLRQLGATIGAVLQTVYSIDNGTGEIASAAQDLSKRTEQQAASLEETAAALEEITSNVTMATKRTDE
ARNVAKEADISAQRSAAVVSQAEGAMRRIEDSSQQISNIIGAIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGFIQKSSADVENGVKLVLETGTSLKSIGEYVVHINQLMDAIATSAREQSTGLAEINTAVNQMDQATQ
QNAAMVEQSTAAVASLSSEAGRLRDLVNQFQLDGDKSAADGQRSGRAFEGNRPIHLVASRRVTQR
>Mature_625_residues
MKRPSIKQALILKLSIITLFMVSLSYVSLSTISTLRANTEQIGTFWMQRLVTAREIKDDFLDLKLVYAQYLLEDTAEERM
VGQQKIDAAGAAVEKVVTEYERGVRTERGRELINQMKPELAKYRALAEQMIALENDGKTPEAIRLFKENMEPQAELVNKA
VADLVAFILGQAEGFVAASGASAQSAFMLTATIAVLAVLLAVAGILFAISGIANPIRSIASAMRRLSDGDLDSDIPYAGR
ADEVGEMAGAVEIFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGEGLRRLASGDISFQLSEQF
AAEYEALREDFNASLRQLGATIGAVLQTVYSIDNGTGEIASAAQDLSKRTEQQAASLEETAAALEEITSNVTMATKRTDE
ARNVAKEADISAQRSAAVVSQAEGAMRRIEDSSQQISNIIGAIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGFIQKSSADVENGVKLVLETGTSLKSIGEYVVHINQLMDAIATSAREQSTGLAEINTAVNQMDQATQ
QNAAMVEQSTAAVASLSSEAGRLRDLVNQFQLDGDKSAADGQRSGRAFEGNRPIHLVASRRVTQR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=41.3907284768212, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788194, Length=294, Percent_Identity=42.1768707482993, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788195, Length=289, Percent_Identity=44.2906574394464, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI2367378, Length=263, Percent_Identity=45.6273764258555, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1789453, Length=277, Percent_Identity=35.0180505415162, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67270; Mature: 67270

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPSIKQALILKLSIITLFMVSLSYVSLSTISTLRANTEQIGTFWMQRLVTAREIKDDF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LDLKLVYAQYLLEDTAEERMVGQQKIDAAGAAVEKVVTEYERGVRTERGRELINQMKPEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKYRALAEQMIALENDGKTPEAIRLFKENMEPQAELVNKAVADLVAFILGQAEGFVAASG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECC
ASAQSAFMLTATIAVLAVLLAVAGILFAISGIANPIRSIASAMRRLSDGDLDSDIPYAGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ADEVGEMAGAVEIFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEGLRRLASGDISFQLSEQFAAEYEALREDFNASLRQLGATIGAVLQTVYSIDNGTGEIA
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SAAQDLSKRTEQQAASLEETAAALEEITSNVTMATKRTDEARNVAKEADISAQRSAAVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
QAEGAMRRIEDSSQQISNIIGAIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRAAQAAKEIKGFIQKSSADVENGVKLVLETGTSLKSIGEYVVHINQLMDAIATSARE
HHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
QSTGLAEINTAVNQMDQATQQNAAMVEQSTAAVASLSSEAGRLRDLVNQFQLDGDKSAAD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GQRSGRAFEGNRPIHLVASRRVTQR
CCCCCCCCCCCCCEEEEECCHHCCC
>Mature Secondary Structure
MKRPSIKQALILKLSIITLFMVSLSYVSLSTISTLRANTEQIGTFWMQRLVTAREIKDDF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LDLKLVYAQYLLEDTAEERMVGQQKIDAAGAAVEKVVTEYERGVRTERGRELINQMKPEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKYRALAEQMIALENDGKTPEAIRLFKENMEPQAELVNKAVADLVAFILGQAEGFVAASG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECC
ASAQSAFMLTATIAVLAVLLAVAGILFAISGIANPIRSIASAMRRLSDGDLDSDIPYAGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ADEVGEMAGAVEIFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEGLRRLASGDISFQLSEQFAAEYEALREDFNASLRQLGATIGAVLQTVYSIDNGTGEIA
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SAAQDLSKRTEQQAASLEETAAALEEITSNVTMATKRTDEARNVAKEADISAQRSAAVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
QAEGAMRRIEDSSQQISNIIGAIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRAAQAAKEIKGFIQKSSADVENGVKLVLETGTSLKSIGEYVVHINQLMDAIATSARE
HHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
QSTGLAEINTAVNQMDQATQQNAAMVEQSTAAVASLSSEAGRLRDLVNQFQLDGDKSAAD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GQRSGRAFEGNRPIHLVASRRVTQR
CCCCCCCCCCCCCEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]