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The map label for this gene is iucD [H]

Identifier: 116248983

GI number: 116248983

Start: 332801

End: 334153

Strand: Reverse

Name: iucD [H]

Synonym: pRL120314

Alternate gene names: 116248983

Gene position: 334153-332801 (Counterclockwise)

Preceding gene: 116248984

Following gene: 116248981

Centisome position: 38.41

GC content: 60.09

Gene sequence:

>1353_bases
ATGACCGTCGCTTTTGCCCGCAGGGATGCCGAGCCGCTGGATATTGCCGGCATCGGCATCGGCCCCTCCAATCTGAGCCT
CGCCTGCCTGTTCGAGTCGGTGCCCGAGATCAGAAGCCGTTTCTTCGAGCGACGAGACTCGTTCGACTGGCATCCCGGCA
TGATGATGCCCGGCGTCGAGTTGCAATCGTCCTTTCTGAAAGACCTCGTCACCCCGGTCCTGCCGACCAGCCGCTGGTCA
TTCGTCTCCTATCTGGTTGCCCATAAGAGGCTCTACGCCTTCCTGAACGCCAATTATGAGGCCGTTCCCCGGCAGGAGTT
TGCACGTTATCTCGCCTGGGTGGCCAACGGGTTGGACGGCCTGCGCTTTGGCACGGAGATCCGTGACGTCGAGCATCGCG
ACGACCGCTTCTTCCTGCGGTTCGACAGCGGGCAGGAGGAGGCGCGAAACCTGGTGATCGGCACGGGATCTCCACCCTTC
GTGCCCGACTGGGCAAAACCGTTTCTGGGTGCTGATTGCTTTCACAACAGCGAGGCCAAATCGCGTCTCAGCGATCTCGG
CGTTGCCCGCATCGTCGTGGTCGGCGGCGGTCAAAGCGGCGGTGAGGTTGTCGAAGCCCTGCTTGCCGATCCCGGTTCCA
TGAAGGAGCTGACATGGATTAGCCGGCGTCACAATTTCGAGCCGATCAACGACACGCCGTTTTCGAACCAAGTCTTCTCA
CCAGAATACGTGCAGGCCTATCTGAAGCTCGGCAGCGAGCAGAAGCAAGCCGCTTTGAAGAACTCGATCCTGACCAGCGA
CGGCTTGTCGATTTCGACGATACACGCGATCTATCGCCGCCTCTATGCATTGCGCTATCTCGAACCGAGCACACTCAACG
CATCTCTGGCGCCAAATCGCGATGTGATTCAGATGGAGCGGAACGGCAATGCCTACCGGCTCATCGTCAGGAACCAATTC
GACGGTGGGATCGAGGTGCTTCATGCGGATGCGGTGGTTCTGGCAACCGGCTACCGGTTCCGGTTACCGGATGCTCTCGG
CTCACTGGGCGACAGGATAACGCTCGACAGAAACGGCTATCCGCTTCTCAATGACGACTACACGATGCAGTGGACGGGTC
CGAGGGCCAACCGGCTGTTTGCGCAGAATGCGGGGCGATACTCGCATGGTATCGCCGATTCTCAGCTCAGCCTCATGGCC
TGGCGCAGCGCAACCATCGTCAATACGCTTCTCGGCCGGCAGCATTTCAATGCAGAACCCGACAATGGGCAACTCGCCTG
GGCGACGGAGACCGCGTCCGCAATGCCTCATCAGCTCCGCGCCGGCTATTCGGACGGCATGCTATCGTCCTGA

Upstream 100 bases:

>100_bases
CCGAAATCATCACCGGCACCAACCATCTGCACATGATCGGGTCTCCCGCCTTCCACTCAAGGCTTGCCCTGCGTCTCAAG
GAAACAGAGAAGGATATCGC

Downstream 100 bases:

>100_bases
AATAGGCGTGTCGAAATGCCGGGGAACCCGGATTGCGAGCAAGCAGCCAGCGCGACGACGTGCTGGCTGCCGCTTTCGAC
CAGACGATGATGCCATCGCC

Product: putative siderophore biosynthesis related protein

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTVAFARRDAEPLDIAGIGIGPSNLSLACLFESVPEIRSRFFERRDSFDWHPGMMMPGVELQSSFLKDLVTPVLPTSRWS
FVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGLDGLRFGTEIRDVEHRDDRFFLRFDSGQEEARNLVIGTGSPPF
VPDWAKPFLGADCFHNSEAKSRLSDLGVARIVVVGGGQSGGEVVEALLADPGSMKELTWISRRHNFEPINDTPFSNQVFS
PEYVQAYLKLGSEQKQAALKNSILTSDGLSISTIHAIYRRLYALRYLEPSTLNASLAPNRDVIQMERNGNAYRLIVRNQF
DGGIEVLHADAVVLATGYRFRLPDALGSLGDRITLDRNGYPLLNDDYTMQWTGPRANRLFAQNAGRYSHGIADSQLSLMA
WRSATIVNTLLGRQHFNAEPDNGQLAWATETASAMPHQLRAGYSDGMLSS

Sequences:

>Translated_450_residues
MTVAFARRDAEPLDIAGIGIGPSNLSLACLFESVPEIRSRFFERRDSFDWHPGMMMPGVELQSSFLKDLVTPVLPTSRWS
FVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGLDGLRFGTEIRDVEHRDDRFFLRFDSGQEEARNLVIGTGSPPF
VPDWAKPFLGADCFHNSEAKSRLSDLGVARIVVVGGGQSGGEVVEALLADPGSMKELTWISRRHNFEPINDTPFSNQVFS
PEYVQAYLKLGSEQKQAALKNSILTSDGLSISTIHAIYRRLYALRYLEPSTLNASLAPNRDVIQMERNGNAYRLIVRNQF
DGGIEVLHADAVVLATGYRFRLPDALGSLGDRITLDRNGYPLLNDDYTMQWTGPRANRLFAQNAGRYSHGIADSQLSLMA
WRSATIVNTLLGRQHFNAEPDNGQLAWATETASAMPHQLRAGYSDGMLSS
>Mature_449_residues
TVAFARRDAEPLDIAGIGIGPSNLSLACLFESVPEIRSRFFERRDSFDWHPGMMMPGVELQSSFLKDLVTPVLPTSRWSF
VSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGLDGLRFGTEIRDVEHRDDRFFLRFDSGQEEARNLVIGTGSPPFV
PDWAKPFLGADCFHNSEAKSRLSDLGVARIVVVGGGQSGGEVVEALLADPGSMKELTWISRRHNFEPINDTPFSNQVFSP
EYVQAYLKLGSEQKQAALKNSILTSDGLSISTIHAIYRRLYALRYLEPSTLNASLAPNRDVIQMERNGNAYRLIVRNQFD
GGIEVLHADAVVLATGYRFRLPDALGSLGDRITLDRNGYPLLNDDYTMQWTGPRANRLFAQNAGRYSHGIADSQLSLMAW
RSATIVNTLLGRQHFNAEPDNGQLAWATETASAMPHQLRAGYSDGMLSS

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 50186; Mature: 50055

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAFARRDAEPLDIAGIGIGPSNLSLACLFESVPEIRSRFFERRDSFDWHPGMMMPGVE
CCEEECCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
LQSSFLKDLVTPVLPTSRWSFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGLDG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCH
LRFGTEIRDVEHRDDRFFLRFDSGQEEARNLVIGTGSPPFVPDWAKPFLGADCFHNSEAK
HHCCCHHHCCCCCCCEEEEEECCCHHHCCEEEEECCCCCCCCCHHHHHCCCHHCCCHHHH
SRLSDLGVARIVVVGGGQSGGEVVEALLADPGSMKELTWISRRHNFEPINDTPFSNQVFS
HHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PEYVQAYLKLGSEQKQAALKNSILTSDGLSISTIHAIYRRLYALRYLEPSTLNASLAPNR
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DVIQMERNGNAYRLIVRNQFDGGIEVLHADAVVLATGYRFRLPDALGSLGDRITLDRNGY
CEEEEECCCCEEEEEEEECCCCCEEEEECCEEEEECCCEEECCHHHHCCCCEEEECCCCC
PLLNDDYTMQWTGPRANRLFAQNAGRYSHGIADSQLSLMAWRSATIVNTLLGRQHFNAEP
CEECCCEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCC
DNGQLAWATETASAMPHQLRAGYSDGMLSS
CCCEEEEEECHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
TVAFARRDAEPLDIAGIGIGPSNLSLACLFESVPEIRSRFFERRDSFDWHPGMMMPGVE
CEEECCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
LQSSFLKDLVTPVLPTSRWSFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGLDG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCH
LRFGTEIRDVEHRDDRFFLRFDSGQEEARNLVIGTGSPPFVPDWAKPFLGADCFHNSEAK
HHCCCHHHCCCCCCCEEEEEECCCHHHCCEEEEECCCCCCCCCHHHHHCCCHHCCCHHHH
SRLSDLGVARIVVVGGGQSGGEVVEALLADPGSMKELTWISRRHNFEPINDTPFSNQVFS
HHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PEYVQAYLKLGSEQKQAALKNSILTSDGLSISTIHAIYRRLYALRYLEPSTLNASLAPNR
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DVIQMERNGNAYRLIVRNQFDGGIEVLHADAVVLATGYRFRLPDALGSLGDRITLDRNGY
CEEEEECCCCEEEEEEEECCCCCEEEEECCEEEEECCCEEECCHHHHCCCCEEEECCCCC
PLLNDDYTMQWTGPRANRLFAQNAGRYSHGIADSQLSLMAWRSATIVNTLLGRQHFNAEP
CEECCCEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCC
DNGQLAWATETASAMPHQLRAGYSDGMLSS
CCCEEEEEECHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]