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The map label for this gene is lnt [H]

Identifier: 114800455

GI number: 114800455

Start: 95356

End: 96999

Strand: Direct

Name: lnt [H]

Synonym: HNE_0107

Alternate gene names: 114800455

Gene position: 95356-96999 (Clockwise)

Preceding gene: 114798310

Following gene: 114799525

Centisome position: 2.57

GC content: 61.44

Gene sequence:

>1644_bases
ATGAGCAAAGCTGTGCGCAGCCACGGGTTCACTGCGCTTGGACCTTTGCATGAGGCTTTTGCCCGCCTGTCTGGTGTGCC
CGCGCTTGCCGCAGCCTTTGCTTTGGGCGCTTTGTCGGCGGTCGCCTTTGCGCCGTTTCATTTCAGCGCTGTGCTGGTGA
TTTCATTCACCGGCCTTGTCTGGATGATTGATGGCGCGCGGTCGCAGGCCAGATGGGGCAGGGCGGTGTTTCTGCGTGGG
TGGGCCTTCGGCACAGGCTTTTTCCTGGTCAGCCTGCATTGGACCGCGATGCCGTTCCTTGTCGATCCGGCCAGAACAAT
CTGGTTCATCTGGATGCCCCTTGTTCTGCTTCCGGCGGGGATGGCGATCATCTGGGGTGTATTCACCGCCATGGCGGGCG
CTTTCTGGTCTGCATCTCCGTCGCGCGTATTTATCTTCTCCCTGTTCTTTGCACTGGCAGAGTTTGTGCGCGGCCACCTC
TTCGGCGGGTTTCCCTGGAACCTTCCGGGTACGACCTGGATGCCCGGCGGCGCCTTGTCTCAGGCGGCGTCCCTGGGGGG
CGTTTACTGGCTGACACTGGTGACGGTGTTTGTCATGGCCTCTCCTGCCGCGCTGGTAGATACGCGCGAAGGGCGCGGCA
TACCGATCAGGGTCGCGCCGGCGCTTGTGTCGGTGGTGGCGCTTGCGCTCGGTTGGGCATGGGGCGCAAACCGCACGGAA
GCGACATCACCGCTTACCGATCAGTCCGTCGTCGTGATGGATGCCGGCGTTCCCCAGGATAAATGGGATACGCTCGGACC
CGATCCTGTACTCTACGAATATCTTCGGATGCTCACCTATCCCGATAGCCGGCCGGGCGACATCGTCGTGTGGCCCGAAG
CGGCTATACCCGCCTACTTGCTGCAGGATGCAAATGCCCTTGATGCGATCGCCGCCTATATCGGCCAGCGAAAGCTGATC
GCCGGCACGACCCGCTATGAGCTCACCACCAATGACAGCCGCATTTATTATAACAGCCTCGCGGTCATGGATGAGACGGT
GAATCAAACCGGTCCTCTTGCGCTCTACGACAAGCACCGGCTGGTGCCGTTTGGAGAACTCGCCGCGATCAACTTCATTC
CTTATGGCCCTCAGTTGAGCAGCCTTTTGCCTCCGACGGTTCAGCGGCTTGCCGCGGATGGGTTCCGTCCCGGCGCGGGC
GCAACCGCGATCGACACTGGCGGGCTTCCAGCGTTCGTGGCGCTGATCTGTTATGAAGGGCTTTTCCCGGAGATAACGCG
CGGCGTGAACGTCACGGACCGGGCGCAATGGATGGTCATGATTTCAAATGACGCCTGGTTCGGCCGGGGTTTGGGGCCGG
CTCAGCATTACGCTCAGAACCGCTACCGCGCGATCGAGACAGGCCTGCCGCTCGTTCGGGCGGCCAATCGTGGAACGTCC
GGCATTATCGACGGCTACGGCCGTGAAATCATGCGTACCATACCGGCTGAAACGGCGCCTGAAGGATGGTCGACGTCTTA
CGGCCGGGCGCGGTTGCCGGTTCCGGCTGACGTTACAATGTTCCAGAGCCGGATCGGGGCGGCGCTTTTCTGGATATCGC
TCTGTGTCTTCGCGGTGCTGGCCTTTCTGACGTGGAGGCGATAA

Upstream 100 bases:

>100_bases
TGAGATTGAAATTGTGGATGCAGACTCGCGGCGGGTTCGCCGTTTGCGTCTGCGTCTGCCAGAGCCACCCCCACAGCCTG
CCGCTGAGGAGTAGAGTTAA

Downstream 100 bases:

>100_bases
GCCCTTCTCTTTAGGGAAACGTCGGTACGTCCGGATTTGTCATGTCAGAAAGCAAACTGCCGAGCGATATCGACCGGGTC
GTGGGGCAAAACATCCATCG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSKAVRSHGFTALGPLHEAFARLSGVPALAAAFALGALSAVAFAPFHFSAVLVISFTGLVWMIDGARSQARWGRAVFLRG
WAFGTGFFLVSLHWTAMPFLVDPARTIWFIWMPLVLLPAGMAIIWGVFTAMAGAFWSASPSRVFIFSLFFALAEFVRGHL
FGGFPWNLPGTTWMPGGALSQAASLGGVYWLTLVTVFVMASPAALVDTREGRGIPIRVAPALVSVVALALGWAWGANRTE
ATSPLTDQSVVVMDAGVPQDKWDTLGPDPVLYEYLRMLTYPDSRPGDIVVWPEAAIPAYLLQDANALDAIAAYIGQRKLI
AGTTRYELTTNDSRIYYNSLAVMDETVNQTGPLALYDKHRLVPFGELAAINFIPYGPQLSSLLPPTVQRLAADGFRPGAG
ATAIDTGGLPAFVALICYEGLFPEITRGVNVTDRAQWMVMISNDAWFGRGLGPAQHYAQNRYRAIETGLPLVRAANRGTS
GIIDGYGREIMRTIPAETAPEGWSTSYGRARLPVPADVTMFQSRIGAALFWISLCVFAVLAFLTWRR

Sequences:

>Translated_547_residues
MSKAVRSHGFTALGPLHEAFARLSGVPALAAAFALGALSAVAFAPFHFSAVLVISFTGLVWMIDGARSQARWGRAVFLRG
WAFGTGFFLVSLHWTAMPFLVDPARTIWFIWMPLVLLPAGMAIIWGVFTAMAGAFWSASPSRVFIFSLFFALAEFVRGHL
FGGFPWNLPGTTWMPGGALSQAASLGGVYWLTLVTVFVMASPAALVDTREGRGIPIRVAPALVSVVALALGWAWGANRTE
ATSPLTDQSVVVMDAGVPQDKWDTLGPDPVLYEYLRMLTYPDSRPGDIVVWPEAAIPAYLLQDANALDAIAAYIGQRKLI
AGTTRYELTTNDSRIYYNSLAVMDETVNQTGPLALYDKHRLVPFGELAAINFIPYGPQLSSLLPPTVQRLAADGFRPGAG
ATAIDTGGLPAFVALICYEGLFPEITRGVNVTDRAQWMVMISNDAWFGRGLGPAQHYAQNRYRAIETGLPLVRAANRGTS
GIIDGYGREIMRTIPAETAPEGWSTSYGRARLPVPADVTMFQSRIGAALFWISLCVFAVLAFLTWRR
>Mature_546_residues
SKAVRSHGFTALGPLHEAFARLSGVPALAAAFALGALSAVAFAPFHFSAVLVISFTGLVWMIDGARSQARWGRAVFLRGW
AFGTGFFLVSLHWTAMPFLVDPARTIWFIWMPLVLLPAGMAIIWGVFTAMAGAFWSASPSRVFIFSLFFALAEFVRGHLF
GGFPWNLPGTTWMPGGALSQAASLGGVYWLTLVTVFVMASPAALVDTREGRGIPIRVAPALVSVVALALGWAWGANRTEA
TSPLTDQSVVVMDAGVPQDKWDTLGPDPVLYEYLRMLTYPDSRPGDIVVWPEAAIPAYLLQDANALDAIAAYIGQRKLIA
GTTRYELTTNDSRIYYNSLAVMDETVNQTGPLALYDKHRLVPFGELAAINFIPYGPQLSSLLPPTVQRLAADGFRPGAGA
TAIDTGGLPAFVALICYEGLFPEITRGVNVTDRAQWMVMISNDAWFGRGLGPAQHYAQNRYRAIETGLPLVRAANRGTSG
IIDGYGREIMRTIPAETAPEGWSTSYGRARLPVPADVTMFQSRIGAALFWISLCVFAVLAFLTWRR

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=483, Percent_Identity=27.3291925465839, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 59319; Mature: 59188

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00136 SUBTILASE_ASP ; PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAVRSHGFTALGPLHEAFARLSGVPALAAAFALGALSAVAFAPFHFSAVLVISFTGLV
CCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
WMIDGARSQARWGRAVFLRGWAFGTGFFLVSLHWTAMPFLVDPARTIWFIWMPLVLLPAG
EEEECCCCHHCCCCEEEEEEEECCCCEEEEEEHHHHCCCEECHHHHHHHHHHHHHHHHHH
MAIIWGVFTAMAGAFWSASPSRVFIFSLFFALAEFVRGHLFGGFPWNLPGTTWMPGGALS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
QAASLGGVYWLTLVTVFVMASPAALVDTREGRGIPIRVAPALVSVVALALGWAWGANRTE
HHHHHCHHHHHHHHHHHHHCCCHHEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCC
ATSPLTDQSVVVMDAGVPQDKWDTLGPDPVLYEYLRMLTYPDSRPGDIVVWPEAAIPAYL
CCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHH
LQDANALDAIAAYIGQRKLIAGTTRYELTTNDSRIYYNSLAVMDETVNQTGPLALYDKHR
HCCCCHHHHHHHHHCCCEEEECCEEEEEECCCCEEEEHHHHHHHHHHCCCCCEEEECCCC
LVPFGELAAINFIPYGPQLSSLLPPTVQRLAADGFRPGAGATAIDTGGLPAFVALICYEG
CCCCCCEEEEEEECCCCCHHHCCCHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHC
LFPEITRGVNVTDRAQWMVMISNDAWFGRGLGPAQHYAQNRYRAIETGLPLVRAANRGTS
CCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
GIIDGYGREIMRTIPAETAPEGWSTSYGRARLPVPADVTMFQSRIGAALFWISLCVFAVL
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AFLTWRR
HHHHCCC
>Mature Secondary Structure 
SKAVRSHGFTALGPLHEAFARLSGVPALAAAFALGALSAVAFAPFHFSAVLVISFTGLV
CCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
WMIDGARSQARWGRAVFLRGWAFGTGFFLVSLHWTAMPFLVDPARTIWFIWMPLVLLPAG
EEEECCCCHHCCCCEEEEEEEECCCCEEEEEEHHHHCCCEECHHHHHHHHHHHHHHHHHH
MAIIWGVFTAMAGAFWSASPSRVFIFSLFFALAEFVRGHLFGGFPWNLPGTTWMPGGALS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
QAASLGGVYWLTLVTVFVMASPAALVDTREGRGIPIRVAPALVSVVALALGWAWGANRTE
HHHHHCHHHHHHHHHHHHHCCCHHEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCC
ATSPLTDQSVVVMDAGVPQDKWDTLGPDPVLYEYLRMLTYPDSRPGDIVVWPEAAIPAYL
CCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHH
LQDANALDAIAAYIGQRKLIAGTTRYELTTNDSRIYYNSLAVMDETVNQTGPLALYDKHR
HCCCCHHHHHHHHHCCCEEEECCEEEEEECCCCEEEEHHHHHHHHHHCCCCCEEEECCCC
LVPFGELAAINFIPYGPQLSSLLPPTVQRLAADGFRPGAGATAIDTGGLPAFVALICYEG
CCCCCCEEEEEEECCCCCHHHCCCHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHC
LFPEITRGVNVTDRAQWMVMISNDAWFGRGLGPAQHYAQNRYRAIETGLPLVRAANRGTS
CCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
GIIDGYGREIMRTIPAETAPEGWSTSYGRARLPVPADVTMFQSRIGAALFWISLCVFAVL
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AFLTWRR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]