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The map label for this gene is tlyC [H]

Identifier: 114798310

GI number: 114798310

Start: 94489

End: 95349

Strand: Direct

Name: tlyC [H]

Synonym: HNE_0106

Alternate gene names: 114798310

Gene position: 94489-95349 (Clockwise)

Preceding gene: 114798379

Following gene: 114800455

Centisome position: 2.55

GC content: 61.44

Gene sequence:

>861_bases
ATGAGCGACTCAGACCCCTCCGACGCCGGCCCGTCCGGCCGATTGCGAAGCCTCTTCGGGTTCCGCAAGAAAACGCCCGA
GCCTGCGACGGCTGCCAGCAGGGACTTGGACCCTGCCGGTGCGCCGCAGGTAATGCGGCTGCGTCTTGCCGAGTTTGAAG
AGTTGCGGGTCGATGATGTCATGGTGCCCCGCGCCGACATAAAAGCGGTCGAAGCAGGCACCGGAATTCAGGAGCTTCTG
GAGTTCTTTGCCGAAGTCACGCATTCCCGCCTTCCTGTATTCCGGGAGTCGCTGGATGATCCGATCGGTTTCGTTCACAT
CAAGGATCTTGTCACGGAGCTGGCAAAGGGCGGGACGCCGCCGCGCCGCCCGCTCGAGAGTCTGCATCGCGAAGTGCTCT
ACGTTCCCCCGTCCATGAAGTTGACGGACCTGCTGGTGAAGATGCAGGCGACGCGTATTCATCTGGCGCTGGTCGTGGAC
GAATATGGCGGCACAGACGGCCTGATCACGCTGGAAGATCTCGTGGAAGTCATCGTGGGCGACATCGAGGACGAACACGA
TGATGAAGAAGCTATGTTCGTTCGGCGAAGCGCGCGTGTCTGGGAAGCCGATGCACGCACGGAAATCGAGGACTTCCAGG
AAGAGGCCGGTGTTGATCTTAGCCTGGATGATCTGGATGCAGACATTGATACGCTGGGCGGCGTCGCCTTCGCGCTTGCC
GGCAAGGTACCGGTTCGCGGGGAAGTGCTACGGCATCCCGGCGGCACTGAGATTGAAATTGTGGATGCAGACTCGCGGCG
GGTTCGCCGTTTGCGTCTGCGTCTGCCAGAGCCACCCCCACAGCCTGCCGCTGAGGAGTAG

Upstream 100 bases:

>100_bases
ATCATGAGACGGACGATGAGGCTGCAGAAATGGAAGCGCTGGAGATAAAGGCGCTTGCTTCCCTCGATATTGCTAATCCA
TACCGGAATGACTGATTGAA

Downstream 100 bases:

>100_bases
AGTTAAATGAGCAAAGCTGTGCGCAGCCACGGGTTCACTGCGCTTGGACCTTTGCATGAGGCTTTTGCCCGCCTGTCTGG
TGTGCCCGCGCTTGCCGCAG

Product: CBS/transporter associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSDSDPSDAGPSGRLRSLFGFRKKTPEPATAASRDLDPAGAPQVMRLRLAEFEELRVDDVMVPRADIKAVEAGTGIQELL
EFFAEVTHSRLPVFRESLDDPIGFVHIKDLVTELAKGGTPPRRPLESLHREVLYVPPSMKLTDLLVKMQATRIHLALVVD
EYGGTDGLITLEDLVEVIVGDIEDEHDDEEAMFVRRSARVWEADARTEIEDFQEEAGVDLSLDDLDADIDTLGGVAFALA
GKVPVRGEVLRHPGGTEIEIVDADSRRVRRLRLRLPEPPPQPAAEE

Sequences:

>Translated_286_residues
MSDSDPSDAGPSGRLRSLFGFRKKTPEPATAASRDLDPAGAPQVMRLRLAEFEELRVDDVMVPRADIKAVEAGTGIQELL
EFFAEVTHSRLPVFRESLDDPIGFVHIKDLVTELAKGGTPPRRPLESLHREVLYVPPSMKLTDLLVKMQATRIHLALVVD
EYGGTDGLITLEDLVEVIVGDIEDEHDDEEAMFVRRSARVWEADARTEIEDFQEEAGVDLSLDDLDADIDTLGGVAFALA
GKVPVRGEVLRHPGGTEIEIVDADSRRVRRLRLRLPEPPPQPAAEE
>Mature_285_residues
SDSDPSDAGPSGRLRSLFGFRKKTPEPATAASRDLDPAGAPQVMRLRLAEFEELRVDDVMVPRADIKAVEAGTGIQELLE
FFAEVTHSRLPVFRESLDDPIGFVHIKDLVTELAKGGTPPRRPLESLHREVLYVPPSMKLTDLLVKMQATRIHLALVVDE
YGGTDGLITLEDLVEVIVGDIEDEHDDEEAMFVRRSARVWEADARTEIEDFQEEAGVDLSLDDLDADIDTLGGVAFALAG
KVPVRGEVLRHPGGTEIEIVDADSRRVRRLRLRLPEPPPQPAAEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=189, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1786879, Length=232, Percent_Identity=34.4827586206897, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI145693175, Length=246, Percent_Identity=26.4227642276423, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790664, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082033, Length=237, Percent_Identity=27.0042194092827, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788119, Length=219, Percent_Identity=28.310502283105, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31582; Mature: 31451

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSDPSDAGPSGRLRSLFGFRKKTPEPATAASRDLDPAGAPQVMRLRLAEFEELRVDDV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCE
MVPRADIKAVEAGTGIQELLEFFAEVTHSRLPVFRESLDDPIGFVHIKDLVTELAKGGTP
ECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEHHHHHHHHHHCCCC
PRRPLESLHREVLYVPPSMKLTDLLVKMQATRIHLALVVDEYGGTDGLITLEDLVEVIVG
CHHHHHHHHHHEEECCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEHHHHHHHHHH
DIEDEHDDEEAMFVRRSARVWEADARTEIEDFQEEAGVDLSLDDLDADIDTLGGVAFALA
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHH
GKVPVRGEVLRHPGGTEIEIVDADSRRVRRLRLRLPEPPPQPAAEE
CCCCCCCHHHCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDSDPSDAGPSGRLRSLFGFRKKTPEPATAASRDLDPAGAPQVMRLRLAEFEELRVDDV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCE
MVPRADIKAVEAGTGIQELLEFFAEVTHSRLPVFRESLDDPIGFVHIKDLVTELAKGGTP
ECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEHHHHHHHHHHCCCC
PRRPLESLHREVLYVPPSMKLTDLLVKMQATRIHLALVVDEYGGTDGLITLEDLVEVIVG
CHHHHHHHHHHEEECCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEHHHHHHHHHH
DIEDEHDDEEAMFVRRSARVWEADARTEIEDFQEEAGVDLSLDDLDADIDTLGGVAFALA
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHH
GKVPVRGEVLRHPGGTEIEIVDADSRRVRRLRLRLPEPPPQPAAEE
CCCCCCCHHHCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA