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The map label for this gene is pepN [H]

Identifier: 114799938

GI number: 114799938

Start: 3067367

End: 3069988

Strand: Reverse

Name: pepN [H]

Synonym: HNE_2911

Alternate gene names: 114799938

Gene position: 3069988-3067367 (Counterclockwise)

Preceding gene: 114798035

Following gene: 114797754

Centisome position: 82.86

GC content: 63.5

Gene sequence:

>2622_bases
ATGCGTACTGAAACTCCCGTCGCCGTCCGCCTTGCTGATTACACGCCCTATCCCTTCTCGATTGATGAGGTCCGTCTGGA
ATTCCGGCTGAACCCCGCTGCCACGCAGGTGCGCGCAACCCTGAAGGTGACCCCGGCAGGCAATGGCCCGATGCGGCTGG
ATGGGGAAGCGCTGACGCTGAAGTCAATCCGGCTGGCAGCAGAAGGCGCCGCGCTCGCACCGCTGGCGGAGGCGGATTAT
TCAGTAGATGAGCATGGCCTCACCCTGACCGCGCCGCCTTCTGGCCCATTCACGCTGGAAACCACGGTCGAGATTTCGCC
GGAGAAGAACACCGCCCTGTCGGGCCTCTATATGTCCGGCGGGCGCTTCTGCACACAGTGTGAAGCCATCGGTTTCCGCC
GCATCACCTTTTACCCCGACCGCCCTGACGTGATGAGCAGTTTCCGTGTGCGGATCGAAGCGGAGAAGGCGGCCAACCCC
TACCTGCTTTCCAATGGTACACCGGGCGAGGCGGGCGACCTTCCAGATGGCTGGCATTTCGCTGAATGGGATGACCCCCA
CAAGAAGCCCGCCTACCTCTTCGCCCTCTGCGCGGGGGAGTATGATGTGCTGCGCGATACGTTCACCACCGCCAGCGGCG
CGCATGTTGATCTGGGCATCTATGTCGACAAGGGCGAAGCGGGCCGGGCGGCGTGGGCGATGGACAGCCTCAAGCGCTCG
ATGCGCTGGGACGAGGAAGCCTATGGCCGGGAATATGATCTCGGCGTGTTCAACATCGTGGCCGTGCGCGACTTCAATTT
CGGCGCCATGGAGAACAAGGGCCTCAATATCTTCAATTCCGCCTATGTGCTGGCTGATGAAGCAACGGCAACGGACGCCG
ACTTTGAAGCCATCGAGTCCATTGTCGCCCACGAATACTTCCACAACTGGACCGGCAACCGCATCACTTGCCGCGACTGG
TTCCAGCTTTGCCTGAAGGAAGGCCTCACGGTCTTCCGGGATCAGAACTTCTCCGCCGACATGCGCTCGCGCCCGGTACA
GCGCATCAAGGACGTGATCCGCCTGCGCGCGCGCCAGTTTGCCGAAGACGCCGGCCCGCTCGCCCATTCGGTGCGCCCGG
ACAATTACGCCGCCATCGACAATCTCTACACCGCGACTGTCTATGAGAAGGGCTCAGAGCTGATCGGCATGCTCCGCCGG
CAGATCGGATCGCAGGATTTCCGGAAGGGCATGGACCTCTATTTCAATCGCCATGACGGCCAGGCCGTCACGATTGAAGA
CTTCTACGCCTGTTTCGAAGCCGCCACGGGGCAGGACTTTTCGCAGTTCCGCCGGTGGTATGCGCAGGCCGGCACGCCTG
AGATCACAGTTGAGGAAAACTGGGACGAGGCCAATACGACCCTGACCGTCAAGCTGTCGCAGTTTACCCGCCCCACAAAT
GGCCAGCCGGTGAAAAAGCCCGTGCCGGTGCCGCTTCTTTCCGCGCTGCTTGACGGGAAAGGCGGGCATGTCGCTGCCAC
GGACCGCGCTGCTGAACCTTTCCTCTATGTGCTCGACACCGAGACGGCGGAAATGGTTTTCCATCTGCCCGCCGGCAGCG
GCCGCCCGCTTGTCTCGCTCAACCGCGATTTCTCGGCGCCCGTGCGTCTGACGCGCGCGCTCAACCGGGATGAACGCCTC
GCGCTCGTCCGTGCCGAGACAGATCCATTCAATACCTGGGATGGCTTGCAGACCCTCATCAAGGAAGAGATCCTTACGCT
CGCGGATGGGTCGCAGAAAGCGCCGGATCTCGCTCTTGTCGGCGCGATTGGTCAGGCCGTGCGCGGCGCCATGAACGACC
CGGCGTTCGCCGCGCTCCTGACCCGCCTGCCGGATGTGGGCGAGCTGTTCCTGGAGCGCGAGCCGGCTGACCCGGTTGCC
CTCGCCGCGGCCCGGCGCAAGTTACAGGCGGCGATTGCCGCAGAGCTTTCGCCCGAGATCACTGAGACACTGGCAGAGCC
CTCGCCGGCGCCCTACAATCCGGGGGCGGAGCAAGCCTCCATCCGGGCGCTGCGCTCAGCCTTCATCCTGCTGCTGGGTG
GTCGCGGGGACGCCGCCGAAACGCTGCATGATCTTTATCGCAATGCTCCGAACATGACCGAACAGCTTTCTGCTCTGCGC
GCGCTGACGCTCTCCACCGGCCCCGGCCGGGAAGAGGCGCTCGCCGATTTCGAGGCGCAATGGAAACAGAACCCGCTGGT
CATGGACAAATGGTTCTCGGTTCAGGCTGCTCTTGGTACGGCAGACGATGTCCGCCGTCTGATCGCCCATCCGGACTTCG
ACCTGCGTAATCCAAACCGGGTCCGCTCGGTCGTGGCCGCCTTCGCCATGCAGAACCTCGCCGCCTTCCATGCGCCCGAT
GGCTCAGGCTATGCCGCCGTGGAAGAAACCATCCTTGCCGCTGACAAGGCCAACCCTGCGCTCGGCGCCCGCCTGATTAC
CGCGTTCGAGCAATGGCGCCTGCTGGAGCCCAAAGCCGGCGCGCAGGCGCAGGCCTGCCTGAAGCGTCTGATCGCGGCCG
GGCTATCCCCAAACGCCATGGATATTGCCCATCGCGCGCTTGAGGGCGACGCCAAAGGTTAA

Upstream 100 bases:

>100_bases
CCCTTTGCCAGAGGGCTGCCCTATGGGCAACGCCCCTCGACGGGCCGGGCCCTGTCCGGTATCCCCTAAAGCCTGTCACC
CCTGCCGGAGACCCTGATTG

Downstream 100 bases:

>100_bases
CTTCGCTGTTAACTTTGTTAACGAACGGTCAATGATTCGCGGGGAAAAGGTAAGGCTGCCTATTTCCCGGAAGTTGCAGA
CGTCAGGCGTCACATTGGCA

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 873; Mature: 873

Protein sequence:

>873_residues
MRTETPVAVRLADYTPYPFSIDEVRLEFRLNPAATQVRATLKVTPAGNGPMRLDGEALTLKSIRLAAEGAALAPLAEADY
SVDEHGLTLTAPPSGPFTLETTVEISPEKNTALSGLYMSGGRFCTQCEAIGFRRITFYPDRPDVMSSFRVRIEAEKAANP
YLLSNGTPGEAGDLPDGWHFAEWDDPHKKPAYLFALCAGEYDVLRDTFTTASGAHVDLGIYVDKGEAGRAAWAMDSLKRS
MRWDEEAYGREYDLGVFNIVAVRDFNFGAMENKGLNIFNSAYVLADEATATDADFEAIESIVAHEYFHNWTGNRITCRDW
FQLCLKEGLTVFRDQNFSADMRSRPVQRIKDVIRLRARQFAEDAGPLAHSVRPDNYAAIDNLYTATVYEKGSELIGMLRR
QIGSQDFRKGMDLYFNRHDGQAVTIEDFYACFEAATGQDFSQFRRWYAQAGTPEITVEENWDEANTTLTVKLSQFTRPTN
GQPVKKPVPVPLLSALLDGKGGHVAATDRAAEPFLYVLDTETAEMVFHLPAGSGRPLVSLNRDFSAPVRLTRALNRDERL
ALVRAETDPFNTWDGLQTLIKEEILTLADGSQKAPDLALVGAIGQAVRGAMNDPAFAALLTRLPDVGELFLEREPADPVA
LAAARRKLQAAIAAELSPEITETLAEPSPAPYNPGAEQASIRALRSAFILLLGGRGDAAETLHDLYRNAPNMTEQLSALR
ALTLSTGPGREEALADFEAQWKQNPLVMDKWFSVQAALGTADDVRRLIAHPDFDLRNPNRVRSVVAAFAMQNLAAFHAPD
GSGYAAVEETILAADKANPALGARLITAFEQWRLLEPKAGAQAQACLKRLIAAGLSPNAMDIAHRALEGDAKG

Sequences:

>Translated_873_residues
MRTETPVAVRLADYTPYPFSIDEVRLEFRLNPAATQVRATLKVTPAGNGPMRLDGEALTLKSIRLAAEGAALAPLAEADY
SVDEHGLTLTAPPSGPFTLETTVEISPEKNTALSGLYMSGGRFCTQCEAIGFRRITFYPDRPDVMSSFRVRIEAEKAANP
YLLSNGTPGEAGDLPDGWHFAEWDDPHKKPAYLFALCAGEYDVLRDTFTTASGAHVDLGIYVDKGEAGRAAWAMDSLKRS
MRWDEEAYGREYDLGVFNIVAVRDFNFGAMENKGLNIFNSAYVLADEATATDADFEAIESIVAHEYFHNWTGNRITCRDW
FQLCLKEGLTVFRDQNFSADMRSRPVQRIKDVIRLRARQFAEDAGPLAHSVRPDNYAAIDNLYTATVYEKGSELIGMLRR
QIGSQDFRKGMDLYFNRHDGQAVTIEDFYACFEAATGQDFSQFRRWYAQAGTPEITVEENWDEANTTLTVKLSQFTRPTN
GQPVKKPVPVPLLSALLDGKGGHVAATDRAAEPFLYVLDTETAEMVFHLPAGSGRPLVSLNRDFSAPVRLTRALNRDERL
ALVRAETDPFNTWDGLQTLIKEEILTLADGSQKAPDLALVGAIGQAVRGAMNDPAFAALLTRLPDVGELFLEREPADPVA
LAAARRKLQAAIAAELSPEITETLAEPSPAPYNPGAEQASIRALRSAFILLLGGRGDAAETLHDLYRNAPNMTEQLSALR
ALTLSTGPGREEALADFEAQWKQNPLVMDKWFSVQAALGTADDVRRLIAHPDFDLRNPNRVRSVVAAFAMQNLAAFHAPD
GSGYAAVEETILAADKANPALGARLITAFEQWRLLEPKAGAQAQACLKRLIAAGLSPNAMDIAHRALEGDAKG
>Mature_873_residues
MRTETPVAVRLADYTPYPFSIDEVRLEFRLNPAATQVRATLKVTPAGNGPMRLDGEALTLKSIRLAAEGAALAPLAEADY
SVDEHGLTLTAPPSGPFTLETTVEISPEKNTALSGLYMSGGRFCTQCEAIGFRRITFYPDRPDVMSSFRVRIEAEKAANP
YLLSNGTPGEAGDLPDGWHFAEWDDPHKKPAYLFALCAGEYDVLRDTFTTASGAHVDLGIYVDKGEAGRAAWAMDSLKRS
MRWDEEAYGREYDLGVFNIVAVRDFNFGAMENKGLNIFNSAYVLADEATATDADFEAIESIVAHEYFHNWTGNRITCRDW
FQLCLKEGLTVFRDQNFSADMRSRPVQRIKDVIRLRARQFAEDAGPLAHSVRPDNYAAIDNLYTATVYEKGSELIGMLRR
QIGSQDFRKGMDLYFNRHDGQAVTIEDFYACFEAATGQDFSQFRRWYAQAGTPEITVEENWDEANTTLTVKLSQFTRPTN
GQPVKKPVPVPLLSALLDGKGGHVAATDRAAEPFLYVLDTETAEMVFHLPAGSGRPLVSLNRDFSAPVRLTRALNRDERL
ALVRAETDPFNTWDGLQTLIKEEILTLADGSQKAPDLALVGAIGQAVRGAMNDPAFAALLTRLPDVGELFLEREPADPVA
LAAARRKLQAAIAAELSPEITETLAEPSPAPYNPGAEQASIRALRSAFILLLGGRGDAAETLHDLYRNAPNMTEQLSALR
ALTLSTGPGREEALADFEAQWKQNPLVMDKWFSVQAALGTADDVRRLIAHPDFDLRNPNRVRSVVAAFAMQNLAAFHAPD
GSGYAAVEETILAADKANPALGARLITAFEQWRLLEPKAGAQAQACLKRLIAAGLSPNAMDIAHRALEGDAKG

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm, Bound To The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=432, Percent_Identity=26.6203703703704, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI61742777, Length=342, Percent_Identity=26.6081871345029, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI61742775, Length=342, Percent_Identity=26.6081871345029, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI132814467, Length=385, Percent_Identity=25.7142857142857, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI310123622, Length=359, Percent_Identity=26.1838440111421, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI310133497, Length=360, Percent_Identity=26.3888888888889, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI157266300, Length=352, Percent_Identity=25.5681818181818, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI94818901, Length=297, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI94818891, Length=297, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI7019561, Length=417, Percent_Identity=24.9400479616307, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI194306629, Length=306, Percent_Identity=24.1830065359477, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI11641261, Length=306, Percent_Identity=24.1830065359477, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI4505029, Length=454, Percent_Identity=22.4669603524229, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1787163, Length=860, Percent_Identity=43.6046511627907, Blast_Score=666, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=492, Percent_Identity=25.2032520325203, Blast_Score=126, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71989071, Length=492, Percent_Identity=25.2032520325203, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17569221, Length=312, Percent_Identity=27.2435897435897, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17569225, Length=469, Percent_Identity=24.7334754797441, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=435, Percent_Identity=23.448275862069, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115533278, Length=435, Percent_Identity=23.448275862069, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193206928, Length=374, Percent_Identity=27.807486631016, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193206926, Length=374, Percent_Identity=27.807486631016, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI133903840, Length=435, Percent_Identity=23.448275862069, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565628, Length=330, Percent_Identity=24.8484848484848, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=356, Percent_Identity=22.752808988764, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71984353, Length=356, Percent_Identity=22.752808988764, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544504, Length=343, Percent_Identity=23.3236151603499, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71990873, Length=310, Percent_Identity=23.2258064516129, Blast_Score=67, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI9755335, Length=413, Percent_Identity=23.0024213075061, Blast_Score=104, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321837, Length=383, Percent_Identity=24.0208877284595, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655257, Length=443, Percent_Identity=27.313769751693, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24655252, Length=443, Percent_Identity=27.313769751693, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24655274, Length=443, Percent_Identity=27.313769751693, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24655260, Length=443, Percent_Identity=27.313769751693, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24655265, Length=443, Percent_Identity=27.313769751693, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24655268, Length=443, Percent_Identity=27.313769751693, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646514, Length=329, Percent_Identity=26.1398176291793, Blast_Score=109, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24646518, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646516, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24651025, Length=232, Percent_Identity=25.4310344827586, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651023, Length=232, Percent_Identity=25.4310344827586, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651021, Length=232, Percent_Identity=25.4310344827586, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161078673, Length=448, Percent_Identity=23.4375, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571901, Length=448, Percent_Identity=23.4375, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221379089, Length=262, Percent_Identity=25.9541984732824, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648786, Length=302, Percent_Identity=24.8344370860927, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646512, Length=331, Percent_Identity=23.8670694864048, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648790, Length=344, Percent_Identity=23.546511627907, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646510, Length=331, Percent_Identity=23.8670694864048, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651016, Length=179, Percent_Identity=26.2569832402235, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358341, Length=242, Percent_Identity=23.9669421487603, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28571792, Length=303, Percent_Identity=25.4125412541254, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330574, Length=253, Percent_Identity=25.296442687747, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550850, Length=353, Percent_Identity=24.0793201133144, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24650973, Length=350, Percent_Identity=24.2857142857143, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24585062, Length=488, Percent_Identity=22.7459016393443, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585064, Length=488, Percent_Identity=22.7459016393443, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585066, Length=488, Percent_Identity=22.7459016393443, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550350, Length=491, Percent_Identity=22.6069246435845, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 95691; Mature: 95691

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTETPVAVRLADYTPYPFSIDEVRLEFRLNPAATQVRATLKVTPAGNGPMRLDGEALTL
CCCCCCEEEEEECCCCCCCCHHEEEEEEEECCHHEEEEEEEEEEECCCCCEEECCCEEEE
KSIRLAAEGAALAPLAEADYSVDEHGLTLTAPPSGPFTLETTVEISPEKNTALSGLYMSG
EHEEEEECCCCCCCHHHCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCEEEEEEECC
GRFCTQCEAIGFRRITFYPDRPDVMSSFRVRIEAEKAANPYLLSNGTPGEAGDLPDGWHF
CCHHHHHHHCCEEEEEECCCCCHHHHHEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCC
AEWDDPHKKPAYLFALCAGEYDVLRDTFTTASGAHVDLGIYVDKGEAGRAAWAMDSLKRS
CCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHH
MRWDEEAYGREYDLGVFNIVAVRDFNFGAMENKGLNIFNSAYVLADEATATDADFEAIES
HCCCHHHCCCEECCCEEEEEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCHHHHHHH
IVAHEYFHNWTGNRITCRDWFQLCLKEGLTVFRDQNFSADMRSRPVQRIKDVIRLRARQF
HHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEECCCCCCHHHHCHHHHHHHHHHHHHHHH
AEDAGPLAHSVRPDNYAAIDNLYTATVYEKGSELIGMLRRQIGSQDFRKGMDLYFNRHDG
HHHCCCHHHCCCCCCCHHHHHHEEEEHHHCCHHHHHHHHHHHCHHHHHCCCCEEEECCCC
QAVTIEDFYACFEAATGQDFSQFRRWYAQAGTPEITVEENWDEANTTLTVKLSQFTRPTN
CEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEHHCCCCCC
GQPVKKPVPVPLLSALLDGKGGHVAATDRAAEPFLYVLDTETAEMVFHLPAGSGRPLVSL
CCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCEEEEEECCCCCCCCEEEE
NRDFSAPVRLTRALNRDERLALVRAETDPFNTWDGLQTLIKEEILTLADGSQKAPDLALV
CCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHH
GAIGQAVRGAMNDPAFAALLTRLPDVGELFLEREPADPVALAAARRKLQAAIAAELSPEI
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
TETLAEPSPAPYNPGAEQASIRALRSAFILLLGGRGDAAETLHDLYRNAPNMTEQLSALR
HHHHCCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHH
ALTLSTGPGREEALADFEAQWKQNPLVMDKWFSVQAALGTADDVRRLIAHPDFDLRNPNR
HHEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
VRSVVAAFAMQNLAAFHAPDGSGYAAVEETILAADKANPALGARLITAFEQWRLLEPKAG
HHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCC
AQAQACLKRLIAAGLSPNAMDIAHRALEGDAKG
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRTETPVAVRLADYTPYPFSIDEVRLEFRLNPAATQVRATLKVTPAGNGPMRLDGEALTL
CCCCCCEEEEEECCCCCCCCHHEEEEEEEECCHHEEEEEEEEEEECCCCCEEECCCEEEE
KSIRLAAEGAALAPLAEADYSVDEHGLTLTAPPSGPFTLETTVEISPEKNTALSGLYMSG
EHEEEEECCCCCCCHHHCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCEEEEEEECC
GRFCTQCEAIGFRRITFYPDRPDVMSSFRVRIEAEKAANPYLLSNGTPGEAGDLPDGWHF
CCHHHHHHHCCEEEEEECCCCCHHHHHEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCC
AEWDDPHKKPAYLFALCAGEYDVLRDTFTTASGAHVDLGIYVDKGEAGRAAWAMDSLKRS
CCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHH
MRWDEEAYGREYDLGVFNIVAVRDFNFGAMENKGLNIFNSAYVLADEATATDADFEAIES
HCCCHHHCCCEECCCEEEEEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCHHHHHHH
IVAHEYFHNWTGNRITCRDWFQLCLKEGLTVFRDQNFSADMRSRPVQRIKDVIRLRARQF
HHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEECCCCCCHHHHCHHHHHHHHHHHHHHHH
AEDAGPLAHSVRPDNYAAIDNLYTATVYEKGSELIGMLRRQIGSQDFRKGMDLYFNRHDG
HHHCCCHHHCCCCCCCHHHHHHEEEEHHHCCHHHHHHHHHHHCHHHHHCCCCEEEECCCC
QAVTIEDFYACFEAATGQDFSQFRRWYAQAGTPEITVEENWDEANTTLTVKLSQFTRPTN
CEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEHHCCCCCC
GQPVKKPVPVPLLSALLDGKGGHVAATDRAAEPFLYVLDTETAEMVFHLPAGSGRPLVSL
CCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCEEEEEECCCCCCCCEEEE
NRDFSAPVRLTRALNRDERLALVRAETDPFNTWDGLQTLIKEEILTLADGSQKAPDLALV
CCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHH
GAIGQAVRGAMNDPAFAALLTRLPDVGELFLEREPADPVALAAARRKLQAAIAAELSPEI
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
TETLAEPSPAPYNPGAEQASIRALRSAFILLLGGRGDAAETLHDLYRNAPNMTEQLSALR
HHHHCCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHH
ALTLSTGPGREEALADFEAQWKQNPLVMDKWFSVQAALGTADDVRRLIAHPDFDLRNPNR
HHEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
VRSVVAAFAMQNLAAFHAPDGSGYAAVEETILAADKANPALGARLITAFEQWRLLEPKAG
HHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCC
AQAQACLKRLIAAGLSPNAMDIAHRALEGDAKG
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647; 8421698 [H]