Click here to switch to the map view.

The map label for this gene is pleC [H]

Identifier: 114797754

GI number: 114797754

Start: 3064870

End: 3067335

Strand: Reverse

Name: pleC [H]

Synonym: HNE_2910

Alternate gene names: 114797754

Gene position: 3067335-3064870 (Counterclockwise)

Preceding gene: 114799938

Following gene: 114799764

Centisome position: 82.79

GC content: 63.63

Gene sequence:

>2466_bases
ATGATTCGCGGGGAAAAGGTAAGGCTGCCTATTTCCCGGAAGTTGCAGACGTCAGGCGTCACATTGGCAAGATCGCAGGC
CCGTTCTCAGCTGAAACCGGCTGTTGCCGCAGAGGATGCGTCAGCAAAGGCTGAGGCACGCCGGCTGCGCGTCCTGGTGC
CGCTGATCCTGGCTCTGCTGGCGGTGGCTCTCGGCCTCAAGGCCTGGGATGAGCGCCAGTCGGCAGAAGCTGTCCGCCTC
AGCCAGATCGAGAGCGAAGCGCGCCATATCGCCGATCGCATCACGGCGGCCGCAAATGTCGCCGTTACCGCGATTTCCAT
CGCTGAGGGCGGCAGCGTTCCGCGCGCGGAAACCGCCAGCCTCACGCCCGGCATCGACGCTATCGTGTCGCTGCGCGACG
CCTCGCAGTCGCCCGACGGATCGCGGCTTGGCGCCGCCGCGACCGTTGCCGGGGAGATGATGGAGCAGGGCGCCCTGATT
GGCCTTTCCGGGCAAGGTGATCTTGTGTTTCTGGCCGCGCTGGACGCGCGCAATCCTGTCATTGCATTGACGCAGGCCTC
CACGATCATTCCGGAACCTGGCAGCGGCGCGCATATATCCGTGCAAGCCGAAGGGCACGTCATCGGCTTCGGAGACCCGG
CTCTGCAACCGGCAGCTTCGGCGGCAGATTTGCAACGTCCTCAGGTGACATCCTCCGGCGGCGTGCGCGCTGCCTCTGCC
TGCGCCCCGGTGGGCGAGGGGAGCGTGTGTGTCTGTGTGACCGTGGATCAGCCCCTGTTCACGCGCGCCGACCTTCTCAG
CCTTGCGATCTTTGCACTGTTGGTTGCCGCGCCGACATTCACCCTGTTTGGCCTCTCCCGCCGGCTTTCGCTACGCCAGC
GGGAAATCGCCATCCAGGAAACCCGCAATGAAGAGTCAGACCGTATCTTGGGCCTTGTCATGCGCGGCGCGCGGGCGGGC
TATTGGGAATGGTATCAGGACGCGAGTGCCTTGTTTCTGAGCGACGGCGCCGCTGACCTTGTCGGGCTTGGCGAAGGCGG
ACGGGCGCCGCTGGAAGAATTGCTCGCCCGCGTTCCCGTCGAAAGCCGGGGCTATGTGAAGGAAGGCTTCTCCAAGGCGC
GCAGCATTGGCTGGGTCCACCTCACTTTCATTGCCCAGACGAGCCCGCTGCGCTGGATCGAAATGCGGGGCAGCATCTCC
ACCGATCCGGTCACCGGCACGACCGTGTTTGGCGGCATCATGATGGACGCGACCGAGCGCAAGCAGGCCGAAGACCGCGT
GAAGACCGCCGAGCGGCGCCTGCGCAATGCCATCGAGGGCTTCAACGGCCCCTTCGCCCTGTGGGATACGCGCAAGCGGC
TGCTCTACTGGAACCGCGCCTTCGCGCTCGACTTCGGCCTTCAGGATACGCTGCGCCCCGGCATGAGCCATGACACGGTG
GTGATCGCGAGGGCAGGCGCTGTGTCTATGGAGCGCCAATCCGAAGAGGACGCGCGCACAACGACAATTGCCCTGCGCAC
CGGCCGCTGGCTGAAGATGGTGGAGCGCGCCACGCCTGATGGCGGGCTGATCACGGTTGGCATTGAAGTGACCGAGAATG
TCCGCAATGAGGAAGAACTCAAGAAGCAGAAGGAAAAGCTGCGCCGCGCCGCGCTCGATCTGGAGCGTTCCGAAGGCCAT
GCCAGTGAGCTGAGCCGAAAGTATTCGGAGGAAAAGGAAAAGGCCGAGCGCGCTGCTCTCGCCAAATCCGCCTTTCTCGC
CAATATGAGCCATGAGCTGCGCACGCCGCTCAACGCGGTCATCGGCTTTTCCGAGATCATGACCAACGAGCTTGCCGGAC
CGCTGGGTGATCCATCGTACAAGGAATATGCCAAGGATATTCTCATGTCCGGCCAGCACCTTCTGGACATGATCAACGAC
ATCCTCGACATGGCCAAGATCGAGGCGGGCAAGATGACCATCAGCCCGCAACCCATCGACCCCATTGATCCGGTTGATGC
GGCGATGCGCATGATCCGCCGCAAGGCCGAGGAGAAGGCGATTGATCTGGTTCTGGAGGCTGAGGATAACCTGCCCGACA
TTGACGCCGACCACCGCGCCATCCGGCAGATGATGCTGAACCTCCTGTCCAACGCCATCAAGTTCACCGACCGTTCCGGC
ACCATCACGGTGCGGGTCGAGCAGCGGGGCACCGACATCTATTTCGGCGTCACCGATACCGGCATCGGCATTCCGGCCGA
AGACCTGCCGCGCCTTGCCCAGCCCTTCGAGCAGGTCGCCAAGACCAAGGACCGCAACCATGAAGGCACCGGCCTTGGCC
TGTCACTGACCAAATCCTTTGCCGAGATGCATGGCGGGCGGATGCTGCTCTCCTCGATCTATGGCGAGGGCACAACCGTG
GCGTTTGTCCTGCCGATCGGCGGGCCGGCGGCGGTCCGCTTCGACATCCAGCGGGATGTTGCCTGA

Upstream 100 bases:

>100_bases
GCGGCCGGGCTATCCCCAAACGCCATGGATATTGCCCATCGCGCGCTTGAGGGCGACGCCAAAGGTTAACTTCGCTGTTA
ACTTTGTTAACGAACGGTCA

Downstream 100 bases:

>100_bases
CGCTTCAGGGCCGCTGGTTCCAGTTCAGGATTTCGCTGACGGATCGCGAGACCGTCAGCTCGCCCCAGGCACCGGTCTTC
AGCTTCCGGTCTAGCCCTTC

Product: non-motile and phage-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 821

Protein sequence:

>821_residues
MIRGEKVRLPISRKLQTSGVTLARSQARSQLKPAVAAEDASAKAEARRLRVLVPLILALLAVALGLKAWDERQSAEAVRL
SQIESEARHIADRITAAANVAVTAISIAEGGSVPRAETASLTPGIDAIVSLRDASQSPDGSRLGAAATVAGEMMEQGALI
GLSGQGDLVFLAALDARNPVIALTQASTIIPEPGSGAHISVQAEGHVIGFGDPALQPAASAADLQRPQVTSSGGVRAASA
CAPVGEGSVCVCVTVDQPLFTRADLLSLAIFALLVAAPTFTLFGLSRRLSLRQREIAIQETRNEESDRILGLVMRGARAG
YWEWYQDASALFLSDGAADLVGLGEGGRAPLEELLARVPVESRGYVKEGFSKARSIGWVHLTFIAQTSPLRWIEMRGSIS
TDPVTGTTVFGGIMMDATERKQAEDRVKTAERRLRNAIEGFNGPFALWDTRKRLLYWNRAFALDFGLQDTLRPGMSHDTV
VIARAGAVSMERQSEEDARTTTIALRTGRWLKMVERATPDGGLITVGIEVTENVRNEEELKKQKEKLRRAALDLERSEGH
ASELSRKYSEEKEKAERAALAKSAFLANMSHELRTPLNAVIGFSEIMTNELAGPLGDPSYKEYAKDILMSGQHLLDMIND
ILDMAKIEAGKMTISPQPIDPIDPVDAAMRMIRRKAEEKAIDLVLEAEDNLPDIDADHRAIRQMMLNLLSNAIKFTDRSG
TITVRVEQRGTDIYFGVTDTGIGIPAEDLPRLAQPFEQVAKTKDRNHEGTGLGLSLTKSFAEMHGGRMLLSSIYGEGTTV
AFVLPIGGPAAVRFDIQRDVA

Sequences:

>Translated_821_residues
MIRGEKVRLPISRKLQTSGVTLARSQARSQLKPAVAAEDASAKAEARRLRVLVPLILALLAVALGLKAWDERQSAEAVRL
SQIESEARHIADRITAAANVAVTAISIAEGGSVPRAETASLTPGIDAIVSLRDASQSPDGSRLGAAATVAGEMMEQGALI
GLSGQGDLVFLAALDARNPVIALTQASTIIPEPGSGAHISVQAEGHVIGFGDPALQPAASAADLQRPQVTSSGGVRAASA
CAPVGEGSVCVCVTVDQPLFTRADLLSLAIFALLVAAPTFTLFGLSRRLSLRQREIAIQETRNEESDRILGLVMRGARAG
YWEWYQDASALFLSDGAADLVGLGEGGRAPLEELLARVPVESRGYVKEGFSKARSIGWVHLTFIAQTSPLRWIEMRGSIS
TDPVTGTTVFGGIMMDATERKQAEDRVKTAERRLRNAIEGFNGPFALWDTRKRLLYWNRAFALDFGLQDTLRPGMSHDTV
VIARAGAVSMERQSEEDARTTTIALRTGRWLKMVERATPDGGLITVGIEVTENVRNEEELKKQKEKLRRAALDLERSEGH
ASELSRKYSEEKEKAERAALAKSAFLANMSHELRTPLNAVIGFSEIMTNELAGPLGDPSYKEYAKDILMSGQHLLDMIND
ILDMAKIEAGKMTISPQPIDPIDPVDAAMRMIRRKAEEKAIDLVLEAEDNLPDIDADHRAIRQMMLNLLSNAIKFTDRSG
TITVRVEQRGTDIYFGVTDTGIGIPAEDLPRLAQPFEQVAKTKDRNHEGTGLGLSLTKSFAEMHGGRMLLSSIYGEGTTV
AFVLPIGGPAAVRFDIQRDVA
>Mature_821_residues
MIRGEKVRLPISRKLQTSGVTLARSQARSQLKPAVAAEDASAKAEARRLRVLVPLILALLAVALGLKAWDERQSAEAVRL
SQIESEARHIADRITAAANVAVTAISIAEGGSVPRAETASLTPGIDAIVSLRDASQSPDGSRLGAAATVAGEMMEQGALI
GLSGQGDLVFLAALDARNPVIALTQASTIIPEPGSGAHISVQAEGHVIGFGDPALQPAASAADLQRPQVTSSGGVRAASA
CAPVGEGSVCVCVTVDQPLFTRADLLSLAIFALLVAAPTFTLFGLSRRLSLRQREIAIQETRNEESDRILGLVMRGARAG
YWEWYQDASALFLSDGAADLVGLGEGGRAPLEELLARVPVESRGYVKEGFSKARSIGWVHLTFIAQTSPLRWIEMRGSIS
TDPVTGTTVFGGIMMDATERKQAEDRVKTAERRLRNAIEGFNGPFALWDTRKRLLYWNRAFALDFGLQDTLRPGMSHDTV
VIARAGAVSMERQSEEDARTTTIALRTGRWLKMVERATPDGGLITVGIEVTENVRNEEELKKQKEKLRRAALDLERSEGH
ASELSRKYSEEKEKAERAALAKSAFLANMSHELRTPLNAVIGFSEIMTNELAGPLGDPSYKEYAKDILMSGQHLLDMIND
ILDMAKIEAGKMTISPQPIDPIDPVDAAMRMIRRKAEEKAIDLVLEAEDNLPDIDADHRAIRQMMLNLLSNAIKFTDRSG
TITVRVEQRGTDIYFGVTDTGIGIPAEDLPRLAQPFEQVAKTKDRNHEGTGLGLSLTKSFAEMHGGRMLLSSIYGEGTTV
AFVLPIGGPAAVRFDIQRDVA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=38.655462184874, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI87081816, Length=277, Percent_Identity=32.8519855595668, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=35.4166666666667, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=36.5145228215768, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=30.7017543859649, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=32.3770491803279, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=27.9835390946502, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=22.7611940298507, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=25.4032258064516, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=27.5303643724696, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=26.1682242990654, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=208, Percent_Identity=25.9615384615385, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88669; Mature: 88669

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRGEKVRLPISRKLQTSGVTLARSQARSQLKPAVAAEDASAKAEARRLRVLVPLILALL
CCCCCEEECCHHHHHHCCCCHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
AVALGLKAWDERQSAEAVRLSQIESEARHIADRITAAANVAVTAISIAEGGSVPRAETAS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCC
LTPGIDAIVSLRDASQSPDGSRLGAAATVAGEMMEQGALIGLSGQGDLVFLAALDARNPV
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCE
IALTQASTIIPEPGSGAHISVQAEGHVIGFGDPALQPAASAADLQRPQVTSSGGVRAASA
EEEEECCEECCCCCCCCEEEEEECCEEEECCCCCCCCCCCHHHCCCCCCCCCCCCEEHHH
CAPVGEGSVCVCVTVDQPLFTRADLLSLAIFALLVAAPTFTLFGLSRRLSLRQREIAIQE
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRNEESDRILGLVMRGARAGYWEWYQDASALFLSDGAADLVGLGEGGRAPLEELLARVPV
HCCCCHHHHHHHHHHCCCCCCHHHHHCCCEEEEECCCCCEEECCCCCCCCHHHHHHHCCC
ESRGYVKEGFSKARSIGWVHLTFIAQTSPLRWIEMRGSISTDPVTGTTVFGGIMMDATER
CCCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHEECCHHH
KQAEDRVKTAERRLRNAIEGFNGPFALWDTRKRLLYWNRAFALDFGLQDTLRPGMSHDTV
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCHHEEECEEEEEECCCHHHHCCCCCCCEE
VIARAGAVSMERQSEEDARTTTIALRTGRWLKMVERATPDGGLITVGIEVTENVRNEEEL
EEEECCCCHHHHCCCCCHHEEEEEEECCHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHH
KKQKEKLRRAALDLERSEGHASELSRKYSEEKEKAERAALAKSAFLANMSHELRTPLNAV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
IGFSEIMTNELAGPLGDPSYKEYAKDILMSGQHLLDMINDILDMAKIEAGKMTISPQPID
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCC
PIDPVDAAMRMIRRKAEEKAIDLVLEAEDNLPDIDADHRAIRQMMLNLLSNAIKFTDRSG
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCC
TITVRVEQRGTDIYFGVTDTGIGIPAEDLPRLAQPFEQVAKTKDRNHEGTGLGLSLTKSF
EEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AEMHGGRMLLSSIYGEGTTVAFVLPIGGPAAVRFDIQRDVA
HHHCCCHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCC
>Mature Secondary Structure
MIRGEKVRLPISRKLQTSGVTLARSQARSQLKPAVAAEDASAKAEARRLRVLVPLILALL
CCCCCEEECCHHHHHHCCCCHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
AVALGLKAWDERQSAEAVRLSQIESEARHIADRITAAANVAVTAISIAEGGSVPRAETAS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCC
LTPGIDAIVSLRDASQSPDGSRLGAAATVAGEMMEQGALIGLSGQGDLVFLAALDARNPV
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCE
IALTQASTIIPEPGSGAHISVQAEGHVIGFGDPALQPAASAADLQRPQVTSSGGVRAASA
EEEEECCEECCCCCCCCEEEEEECCEEEECCCCCCCCCCCHHHCCCCCCCCCCCCEEHHH
CAPVGEGSVCVCVTVDQPLFTRADLLSLAIFALLVAAPTFTLFGLSRRLSLRQREIAIQE
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRNEESDRILGLVMRGARAGYWEWYQDASALFLSDGAADLVGLGEGGRAPLEELLARVPV
HCCCCHHHHHHHHHHCCCCCCHHHHHCCCEEEEECCCCCEEECCCCCCCCHHHHHHHCCC
ESRGYVKEGFSKARSIGWVHLTFIAQTSPLRWIEMRGSISTDPVTGTTVFGGIMMDATER
CCCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHEECCHHH
KQAEDRVKTAERRLRNAIEGFNGPFALWDTRKRLLYWNRAFALDFGLQDTLRPGMSHDTV
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCHHEEECEEEEEECCCHHHHCCCCCCCEE
VIARAGAVSMERQSEEDARTTTIALRTGRWLKMVERATPDGGLITVGIEVTENVRNEEEL
EEEECCCCHHHHCCCCCHHEEEEEEECCHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHH
KKQKEKLRRAALDLERSEGHASELSRKYSEEKEKAERAALAKSAFLANMSHELRTPLNAV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
IGFSEIMTNELAGPLGDPSYKEYAKDILMSGQHLLDMINDILDMAKIEAGKMTISPQPID
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCC
PIDPVDAAMRMIRRKAEEKAIDLVLEAEDNLPDIDADHRAIRQMMLNLLSNAIKFTDRSG
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCC
TITVRVEQRGTDIYFGVTDTGIGIPAEDLPRLAQPFEQVAKTKDRNHEGTGLGLSLTKSF
EEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AEMHGGRMLLSSIYGEGTTVAFVLPIGGPAAVRFDIQRDVA
HHHCCCHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]