Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 114799741

GI number: 114799741

Start: 1786424

End: 1787032

Strand: Direct

Name: nuoC

Synonym: HNE_1744

Alternate gene names: 114799741

Gene position: 1786424-1787032 (Clockwise)

Preceding gene: 114799608

Following gene: 114800277

Centisome position: 48.22

GC content: 60.26

Gene sequence:

>609_bases
ATGGATACTCAGGCGCTTTCCGATCTTGCCGCCCATATCGAAGGGCGCATGCCCGATGCTGTGCGTAGTTGGCAGATCCA
TGTCGGCGAACTCACGCTGCTCGCCGAGCGGGACCATATTGTCCCGCTGCTTCGCTTCCTGCGCGACGATCAGCAATGTA
ACTTTGAAACCTTCATCGATGTCTGCGGCGTGGATTATCCCGAGCGCTCGGAGCGTTTCGAGGTGGTCTACCACCTGCTG
TCGATGCGCATGAACCACCGCATCCGCGTGCGTATCCGCACCGATGAGGAAACTGCGGTGCCCAGCGTCGTGTCCCTCTG
GCCGGCCGCCAACTGGTTCGAGCGCGAAGCGTTCGACATGTATGGCATCCAGTTTGCCGACCATCCCGACCTGCGCCGCA
TTCTGACTGACTATGGCTTCGAAGGCTGGCCGCTCCGCAAGGACTTCCCGCTGACGGGCCATTACGAGGTGCGCTATGAC
GACCTCGAGAAGCGCGTGATCTACGAGCCGGTGAAGCTCGCCCAAGAATACCGCAATTTCGATTTCCTCTCGCCCTGGGA
AGGCATGACGACCGTCATCCCCGGCGACGAGAAAGCGAAGGAAGGCTGA

Upstream 100 bases:

>100_bases
CAGGCTGCCCGCCCACCGCTGAGGCGCTCGTCTACGGCTTCCTTCAGCTGCAGAAGAAGATCCGCCGCGAAGGTTCGATC
GAACGCTGATGGTGACGATG

Downstream 100 bases:

>100_bases
TCAGATGGCCGACACCGTGCACATCGCAGACATGGACGACCGCAAGTTCACGCTGAACTTCGGCCCTCAGCACCCCGCCG
CTCACGGCGTGCTCCGCATG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDTQALSDLAAHIEGRMPDAVRSWQIHVGELTLLAERDHIVPLLRFLRDDQQCNFETFIDVCGVDYPERSERFEVVYHLL
SMRMNHRIRVRIRTDEETAVPSVVSLWPAANWFEREAFDMYGIQFADHPDLRRILTDYGFEGWPLRKDFPLTGHYEVRYD
DLEKRVIYEPVKLAQEYRNFDFLSPWEGMTTVIPGDEKAKEG

Sequences:

>Translated_202_residues
MDTQALSDLAAHIEGRMPDAVRSWQIHVGELTLLAERDHIVPLLRFLRDDQQCNFETFIDVCGVDYPERSERFEVVYHLL
SMRMNHRIRVRIRTDEETAVPSVVSLWPAANWFEREAFDMYGIQFADHPDLRRILTDYGFEGWPLRKDFPLTGHYEVRYD
DLEKRVIYEPVKLAQEYRNFDFLSPWEGMTTVIPGDEKAKEG
>Mature_202_residues
MDTQALSDLAAHIEGRMPDAVRSWQIHVGELTLLAERDHIVPLLRFLRDDQQCNFETFIDVCGVDYPERSERFEVVYHLL
SMRMNHRIRVRIRTDEETAVPSVVSLWPAANWFEREAFDMYGIQFADHPDLRRILTDYGFEGWPLRKDFPLTGHYEVRYD
DLEKRVIYEPVKLAQEYRNFDFLSPWEGMTTVIPGDEKAKEG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=187, Percent_Identity=52.4064171122995, Blast_Score=205, Evalue=2e-53,
Organism=Escherichia coli, GI145693162, Length=141, Percent_Identity=34.0425531914894, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=183, Percent_Identity=48.6338797814208, Blast_Score=187, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI32563621, Length=183, Percent_Identity=48.6338797814208, Blast_Score=186, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=54.0983606557377, Blast_Score=206, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_HYPNA (Q0C1E5)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760448.1
- ProteinModelPortal:   Q0C1E5
- SMR:   Q0C1E5
- STRING:   Q0C1E5
- GeneID:   4288025
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1744
- NMPDR:   fig|228405.5.peg.1679
- TIGR:   HNE_1744
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   HNEP81032:HNE_1744-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23852; Mature: 23852

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQALSDLAAHIEGRMPDAVRSWQIHVGELTLLAERDHIVPLLRFLRDDQQCNFETFID
CCHHHHHHHHHHHCCCCCHHHHHHEEEECEEEEEECCCHHHHHHHHHCCCCCCCHHHHHH
VCGVDYPERSERFEVVYHLLSMRMNHRIRVRIRTDEETAVPSVVSLWPAANWFEREAFDM
HHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
YGIQFADHPDLRRILTDYGFEGWPLRKDFPLTGHYEVRYDDLEKRVIYEPVKLAQEYRNF
HCCEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCC
DFLSPWEGMTTVIPGDEKAKEG
CCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MDTQALSDLAAHIEGRMPDAVRSWQIHVGELTLLAERDHIVPLLRFLRDDQQCNFETFID
CCHHHHHHHHHHHCCCCCHHHHHHEEEECEEEEEECCCHHHHHHHHHCCCCCCCHHHHHH
VCGVDYPERSERFEVVYHLLSMRMNHRIRVRIRTDEETAVPSVVSLWPAANWFEREAFDM
HHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
YGIQFADHPDLRRILTDYGFEGWPLRKDFPLTGHYEVRYDDLEKRVIYEPVKLAQEYRNF
HCCEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCC
DFLSPWEGMTTVIPGDEKAKEG
CCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA