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The map label for this gene is cirA [H]

Identifier: 114799533

GI number: 114799533

Start: 1692075

End: 1694474

Strand: Direct

Name: cirA [H]

Synonym: HNE_1653

Alternate gene names: 114799533

Gene position: 1692075-1694474 (Clockwise)

Preceding gene: 114798499

Following gene: 114799766

Centisome position: 45.67

GC content: 58.75

Gene sequence:

>2400_bases
ATGAAATCCTATCTCGCCCGGAAGGCCGTCATCAACGGCGCCATGCTCGCCGCTGTCCTCTCAGGACCGGCCGCTTTCGC
TGATGAAACCGATACAGAACGCCAGATGCGCCTCAACGAGATCGTCGTCACCGCCGCCGGCTTCGAACAGAAGCTCGTCG
ACGCCCCTGCCAGCATCAGCATCGTGACGGTAGAGGAGCTCAAGGAGCGCCCTTACATGACCCTCATTGATGCCGTCCGC
GATCTGGAAGGCGTAGATGTCGGAGAAACCTCAGACAAAACAGGGCAGCGCACGATCAGCATGCGCGGGATGGGCTCCGA
CTACACGCTCGTCCTGATCAACGGCAAACGCCAGAACAACCATGGCGACATCTATCCCAACAATTTCGGCGGCAACCAGT
TCAACCACATTCCGCCCCTGGACACGATCGAGCAGATCGAGGTCATCCGCGGTCCAGCATCCACCCTCTATGGCTCCGAT
GCGCTGGGCGGTGTCATCAACATCATCACCAAGAAGGTCGCCGATCGCTGGACTGGCTCGGGCACCATCAGCCGCAGTAT
TCAGGAAGACAGCGCCTTCGGTGACGATACGACCGTCGACCTCTTCGCCTCCGGCCCGCTGGTGCCAGGCAAGCTCAATC
TGAGTGGCCGGGGCAGCTGGTACAAACGCGATGCGTCCAATCCGGCCTATGAGCCTGTAACGGATCCCGACGGCAATATC
GTCAACCGCTCACTGGGCTTTGGCGGCGGCGGCAAGACAGTGGACAACACCAACATCTCCTACGGCTTCACCCTCGCCTG
GGTGCCCACCGCCAACCAGACCATCACATTCGACTATGATGGCTCCAAGCAGGACTACGACAACAAGATCAAGATCAACG
ACGAGGGCGAAGAAGAATACCCGGTCGGTACGGTCGACAACATCAACAGCATTTTCACCGCCGGCAACTATTGCCTGGGC
GCCGCCGGGCGGAACGAAGAAGCCTGCCTTGAGGGCGGCGGAACCTGGGCGCGCCGCGCCAATCCCCGCGTCGGCTACAG
CCCGACACAGGAGTTCACGCGCGACAGCTGGTCATTGACGCATGACGGGGAGTGGGGCTTCGGCAACAGCTTTGTCTCGC
TGGCCTATTTTGCCACCAACAATAATGGCCGCACATTGCCGTTCAGCGTGGCAGAGCGTGAACTGCTGCTCGAAATCGTT
GATGGCACCGGCGAATATGCCGGTCTGACTGAGGACGAGCGCCGCAACATTGCCGAGACCACCTTCCTTCCACGTCCCAA
GCGGACACTGGAAAGCGCGCAATATACCCTCGATGCCAAACTCGACATGCCGTTTGAATTTGCTGGCAAGCACACCGTTG
TTGTGGGTGGTCAGGTTATTCAGGGCGAGTTGACCGATGGCGTGTTCGGCCTGGAAGATGGTACGGCCGGTGAGGCGCAG
GAACACAACATGTTCTCGCTGTTCGCCGAGGATACTTGGGAGATCGTCGAGCCCTTCTCGCTGACGGGCGGTGTGCGCTA
TGACAATCACGATGTGTTTGGAGATCAGGTCAGCCCGCGCATATATGGCGTCTACACCATTTCGCCGAGCCTGACGCTGA
AAGGCGGCGTCAGCACCGGTTTCAAGACGCCCAAAACCACCCAGCTCTATGACGGTGTCGTCGGCTTTGGCGGACAGGGA
ACATCACCCTTCTTCGGCAATCCGGACCTTGAGCCGGAAACCAGCACGAGCGCTGAAATCGCCGTCTACTGGCAGCATTC
CAATGGCCACAACTTCAACGCAACCGTGTTCCGCAACGAGTTCAGCGACAAGATCGCTTCGCAGCCTTGCGGCATCGGGC
TGGAGCTCAGCTGCTCCAGCACCGGGGAGTATGCTGACCTGGGGTATGCCACGAGCAGCAAGACGGTGAACATTGACGAA
GTGGTGATTGAGGGGGCCGAACTGGCCGGCCGCTATGAGATCCTCGACAATCTGAGCTTCCGTGCCAACTATACGTATAC
GGACAGCGAACAGAAAAGCGGCGCGCAGGCGGGCCAGCCCCTGAACAATACCGCCAAGCACATGGCCAATGCGACGCTCG
ACTGGTCAATTACGGACAGGTTCAGCACGCAGCTGTCGGTCGAAGCCCGTTCCAAACGCTATCGGGGTGTGAGCAGCACG
ACGGGGGATCATCTGTACTACAAGGACTATGAGCTGTTTAATCTTGGCGCCCAGTACCGCGTGAATGACTTCGTGACGCT
CAGTGGCCGGGTGAACAATCTGCTGGATGAGGATTTCACCAGCTACCAGTATGAATTCCTCGACAATGGCGACGGCACAT
ATGAGCTGAGCACGCAGGACAACTACAACATCAAGGACAAAGCCCGTAGTTTCTGGGTCAGCATGAACGTCCGCTTCTGA

Upstream 100 bases:

>100_bases
TATAGATATATAAATTGAGAATGATAATCATTTTTGCTTGATCCGCTGGGCGTATGCACGTAGGGAGACTGAGAATAATT
CGCAATCGCAGGGGTCTGCA

Downstream 100 bases:

>100_bases
TCCTGTAATTCCGGCATCAGAATTGACCTGAAACAGACAGGCGCTCGCGACATGCGGGCGCCTGTTCATTTTCTGGGGAA
TTCTACCGCAATGCCTTCAT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 799; Mature: 799

Protein sequence:

>799_residues
MKSYLARKAVINGAMLAAVLSGPAAFADETDTERQMRLNEIVVTAAGFEQKLVDAPASISIVTVEELKERPYMTLIDAVR
DLEGVDVGETSDKTGQRTISMRGMGSDYTLVLINGKRQNNHGDIYPNNFGGNQFNHIPPLDTIEQIEVIRGPASTLYGSD
ALGGVINIITKKVADRWTGSGTISRSIQEDSAFGDDTTVDLFASGPLVPGKLNLSGRGSWYKRDASNPAYEPVTDPDGNI
VNRSLGFGGGGKTVDNTNISYGFTLAWVPTANQTITFDYDGSKQDYDNKIKINDEGEEEYPVGTVDNINSIFTAGNYCLG
AAGRNEEACLEGGGTWARRANPRVGYSPTQEFTRDSWSLTHDGEWGFGNSFVSLAYFATNNNGRTLPFSVAERELLLEIV
DGTGEYAGLTEDERRNIAETTFLPRPKRTLESAQYTLDAKLDMPFEFAGKHTVVVGGQVIQGELTDGVFGLEDGTAGEAQ
EHNMFSLFAEDTWEIVEPFSLTGGVRYDNHDVFGDQVSPRIYGVYTISPSLTLKGGVSTGFKTPKTTQLYDGVVGFGGQG
TSPFFGNPDLEPETSTSAEIAVYWQHSNGHNFNATVFRNEFSDKIASQPCGIGLELSCSSTGEYADLGYATSSKTVNIDE
VVIEGAELAGRYEILDNLSFRANYTYTDSEQKSGAQAGQPLNNTAKHMANATLDWSITDRFSTQLSVEARSKRYRGVSST
TGDHLYYKDYELFNLGAQYRVNDFVTLSGRVNNLLDEDFTSYQYEFLDNGDGTYELSTQDNYNIKDKARSFWVSMNVRF

Sequences:

>Translated_799_residues
MKSYLARKAVINGAMLAAVLSGPAAFADETDTERQMRLNEIVVTAAGFEQKLVDAPASISIVTVEELKERPYMTLIDAVR
DLEGVDVGETSDKTGQRTISMRGMGSDYTLVLINGKRQNNHGDIYPNNFGGNQFNHIPPLDTIEQIEVIRGPASTLYGSD
ALGGVINIITKKVADRWTGSGTISRSIQEDSAFGDDTTVDLFASGPLVPGKLNLSGRGSWYKRDASNPAYEPVTDPDGNI
VNRSLGFGGGGKTVDNTNISYGFTLAWVPTANQTITFDYDGSKQDYDNKIKINDEGEEEYPVGTVDNINSIFTAGNYCLG
AAGRNEEACLEGGGTWARRANPRVGYSPTQEFTRDSWSLTHDGEWGFGNSFVSLAYFATNNNGRTLPFSVAERELLLEIV
DGTGEYAGLTEDERRNIAETTFLPRPKRTLESAQYTLDAKLDMPFEFAGKHTVVVGGQVIQGELTDGVFGLEDGTAGEAQ
EHNMFSLFAEDTWEIVEPFSLTGGVRYDNHDVFGDQVSPRIYGVYTISPSLTLKGGVSTGFKTPKTTQLYDGVVGFGGQG
TSPFFGNPDLEPETSTSAEIAVYWQHSNGHNFNATVFRNEFSDKIASQPCGIGLELSCSSTGEYADLGYATSSKTVNIDE
VVIEGAELAGRYEILDNLSFRANYTYTDSEQKSGAQAGQPLNNTAKHMANATLDWSITDRFSTQLSVEARSKRYRGVSST
TGDHLYYKDYELFNLGAQYRVNDFVTLSGRVNNLLDEDFTSYQYEFLDNGDGTYELSTQDNYNIKDKARSFWVSMNVRF
>Mature_799_residues
MKSYLARKAVINGAMLAAVLSGPAAFADETDTERQMRLNEIVVTAAGFEQKLVDAPASISIVTVEELKERPYMTLIDAVR
DLEGVDVGETSDKTGQRTISMRGMGSDYTLVLINGKRQNNHGDIYPNNFGGNQFNHIPPLDTIEQIEVIRGPASTLYGSD
ALGGVINIITKKVADRWTGSGTISRSIQEDSAFGDDTTVDLFASGPLVPGKLNLSGRGSWYKRDASNPAYEPVTDPDGNI
VNRSLGFGGGGKTVDNTNISYGFTLAWVPTANQTITFDYDGSKQDYDNKIKINDEGEEEYPVGTVDNINSIFTAGNYCLG
AAGRNEEACLEGGGTWARRANPRVGYSPTQEFTRDSWSLTHDGEWGFGNSFVSLAYFATNNNGRTLPFSVAERELLLEIV
DGTGEYAGLTEDERRNIAETTFLPRPKRTLESAQYTLDAKLDMPFEFAGKHTVVVGGQVIQGELTDGVFGLEDGTAGEAQ
EHNMFSLFAEDTWEIVEPFSLTGGVRYDNHDVFGDQVSPRIYGVYTISPSLTLKGGVSTGFKTPKTTQLYDGVVGFGGQG
TSPFFGNPDLEPETSTSAEIAVYWQHSNGHNFNATVFRNEFSDKIASQPCGIGLELSCSSTGEYADLGYATSSKTVNIDE
VVIEGAELAGRYEILDNLSFRANYTYTDSEQKSGAQAGQPLNNTAKHMANATLDWSITDRFSTQLSVEARSKRYRGVSST
TGDHLYYKDYELFNLGAQYRVNDFVTLSGRVNNLLDEDFTSYQYEFLDNGDGTYELSTQDNYNIKDKARSFWVSMNVRF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=771, Percent_Identity=29.8313878080415, Blast_Score=285, Evalue=1e-77,
Organism=Escherichia coli, GI1786798, Length=393, Percent_Identity=22.64631043257, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790405, Length=204, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87508; Mature: 87508

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYLARKAVINGAMLAAVLSGPAAFADETDTERQMRLNEIVVTAAGFEQKLVDAPASIS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEEEEECCCHHHHHCCCCCEE
IVTVEELKERPYMTLIDAVRDLEGVDVGETSDKTGQRTISMRGMGSDYTLVLINGKRQNN
EEEHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCC
HGDIYPNNFGGNQFNHIPPLDTIEQIEVIRGPASTLYGSDALGGVINIITKKVADRWTGS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCC
GTISRSIQEDSAFGDDTTVDLFASGPLVPGKLNLSGRGSWYKRDASNPAYEPVTDPDGNI
CCEECCHHHCCCCCCCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCE
VNRSLGFGGGGKTVDNTNISYGFTLAWVPTANQTITFDYDGSKQDYDNKIKINDEGEEEY
EEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCEEEECCCCCCCC
PVGTVDNINSIFTAGNYCLGAAGRNEEACLEGGGTWARRANPRVGYSPTQEFTRDSWSLT
CCCCCCCCHHHHCCCCEEEECCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEE
HDGEWGFGNSFVSLAYFATNNNGRTLPFSVAERELLLEIVDGTGEYAGLTEDERRNIAET
ECCCCCCCCCEEEEEEEEECCCCCEEEHHHHHHHEEHHEECCCCCCCCCCCHHHCCHHHH
TFLPRPKRTLESAQYTLDAKLDMPFEFAGKHTVVVGGQVIQGELTDGVFGLEDGTAGEAQ
HCCCCCHHHHHCCEEEEEEEECCCHHHCCCEEEEECCEEEEEECCCCEEECCCCCCCCCC
EHNMFSLFAEDTWEIVEPFSLTGGVRYDNHDVFGDQVSPRIYGVYTISPSLTLKGGVSTG
CCCEEEEEECCCHHHHCCEECCCCEEECCCCCCCCCCCCEEEEEEEECCCEEEECCCCCC
FKTPKTTQLYDGVVGFGGQGTSPFFGNPDLEPETSTSAEIAVYWQHSNGHNFNATVFRNE
CCCCCCCHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCH
FSDKIASQPCGIGLELSCSSTGEYADLGYATSSKTVNIDEVVIEGAELAGRYEILDNLSF
HHHHHHCCCCCCCEEEEECCCCCCCCCCEECCCCEEEHHHHEEECHHHCCHHHHHHCCEE
RANYTYTDSEQKSGAQAGQPLNNTAKHMANATLDWSITDRFSTQLSVEARSKRYRGVSST
EEEEEECCCHHHCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCEEEEEEHHHHCCCCCCC
TGDHLYYKDYELFNLGAQYRVNDFVTLSGRVNNLLDEDFTSYQYEFLDNGDGTYELSTQD
CCCEEEEECEEEEECCCCEEECEEEEECCHHHHHHHHCCCCEEEEEEECCCCEEEECCCC
NYNIKDKARSFWVSMNVRF
CCCHHHCCEEEEEEEEEEC
>Mature Secondary Structure
MKSYLARKAVINGAMLAAVLSGPAAFADETDTERQMRLNEIVVTAAGFEQKLVDAPASIS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEEEEECCCHHHHHCCCCCEE
IVTVEELKERPYMTLIDAVRDLEGVDVGETSDKTGQRTISMRGMGSDYTLVLINGKRQNN
EEEHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCC
HGDIYPNNFGGNQFNHIPPLDTIEQIEVIRGPASTLYGSDALGGVINIITKKVADRWTGS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCC
GTISRSIQEDSAFGDDTTVDLFASGPLVPGKLNLSGRGSWYKRDASNPAYEPVTDPDGNI
CCEECCHHHCCCCCCCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCE
VNRSLGFGGGGKTVDNTNISYGFTLAWVPTANQTITFDYDGSKQDYDNKIKINDEGEEEY
EEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCEEEECCCCCCCC
PVGTVDNINSIFTAGNYCLGAAGRNEEACLEGGGTWARRANPRVGYSPTQEFTRDSWSLT
CCCCCCCCHHHHCCCCEEEECCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEE
HDGEWGFGNSFVSLAYFATNNNGRTLPFSVAERELLLEIVDGTGEYAGLTEDERRNIAET
ECCCCCCCCCEEEEEEEEECCCCCEEEHHHHHHHEEHHEECCCCCCCCCCCHHHCCHHHH
TFLPRPKRTLESAQYTLDAKLDMPFEFAGKHTVVVGGQVIQGELTDGVFGLEDGTAGEAQ
HCCCCCHHHHHCCEEEEEEEECCCHHHCCCEEEEECCEEEEEECCCCEEECCCCCCCCCC
EHNMFSLFAEDTWEIVEPFSLTGGVRYDNHDVFGDQVSPRIYGVYTISPSLTLKGGVSTG
CCCEEEEEECCCHHHHCCEECCCCEEECCCCCCCCCCCCEEEEEEEECCCEEEECCCCCC
FKTPKTTQLYDGVVGFGGQGTSPFFGNPDLEPETSTSAEIAVYWQHSNGHNFNATVFRNE
CCCCCCCHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCH
FSDKIASQPCGIGLELSCSSTGEYADLGYATSSKTVNIDEVVIEGAELAGRYEILDNLSF
HHHHHHCCCCCCCEEEEECCCCCCCCCCEECCCCEEEHHHHEEECHHHCCHHHHHHCCEE
RANYTYTDSEQKSGAQAGQPLNNTAKHMANATLDWSITDRFSTQLSVEARSKRYRGVSST
EEEEEECCCHHHCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCEEEEEEHHHHCCCCCCC
TGDHLYYKDYELFNLGAQYRVNDFVTLSGRVNNLLDEDFTSYQYEFLDNGDGTYELSTQD
CCCEEEEECEEEEECCCCEEECEEEEECCHHHHHHHHCCCCEEEEEEECCCCEEEECCCC
NYNIKDKARSFWVSMNVRF
CCCHHHCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]