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The map label for this gene is apbE [H]

Identifier: 114798499

GI number: 114798499

Start: 1690915

End: 1691889

Strand: Direct

Name: apbE [H]

Synonym: HNE_1652

Alternate gene names: 114798499

Gene position: 1690915-1691889 (Clockwise)

Preceding gene: 114799602

Following gene: 114799533

Centisome position: 45.64

GC content: 66.15

Gene sequence:

>975_bases
TTGAGCGGGGCCAACCTCATCATACCTGACGATTTCGGCCGCGGTGACATCACACCGCGGCCGGACGCATTTATGGGCCA
GCGCCTCACCGGCGAAACCATGGGCACCACATGGTCGGCCAGCTGGTGCGCCGCCCCCGGACTATCCGAGGAGAGGGTGA
AGGCGGCGCTGGAGGCCAACTTCGCAGCGATCATTTCCTCCATGAGCCCGTGGGAGCCTGCCTCCCTCATATCGCAATTC
AACCGCCTTCCGCGCGGCGGCAGTCTCGCCATCGACACGGCCTTTGCCGAAGTGATGGCGATGGCGCTGGAGGTGGCTGA
TGCCTCCGGCGGCGCCTTCGATCCCTGCCTCGGCGGCGCAGTCATGCGCCGGGGGTTTGGCCCTGCCGGTATTGGCGCGG
GGCAGGAGGGCAGGGCGCATGGCCCCGCCGTGTGGAGCCAGCTGCTGCCCGAACCTGTCCGCCTCTATCAGCCCGGCGGT
GTCACGCTGGACCTCAACGCCGTCGCCAAGGGCTACGCCGTCGATCAGATGGGCCGCGTGCTTGAGGGGCTTGGCCTCAC
CCAGTTCCTCGTCGAAATCGGCGGCGAGTTCACCGCGCGGGGCGTGAAGCCGGACCGGTCGCCCTGGTGGGTCGATCTGG
AAAACCCGTCACCTCAAGAGGCGCCGTGGCGTCTTGCGCTGGTCGGTCATGGTGTGGCGACGTCTGGCGACTATCGGCAG
CAAGTTGTCCAGAATTGTCTCAAAGTGTCCCACATCGTCCCGGCGATGACCCGGCAATGTAGCCAGTTGGACCTCGCCTG
CGTCACGGTTGTCCACGATAATTGCGCCCTTGCAGACGCCTGGGCCACCGCGCTTTTCGCCATGGGCGATACAGCCAGCC
TCACCCTCGCCAACCGTCTGAACCTCCCCATCCTCCTGCAATACCGCGACGCCCCTGCCAGGGCGTCGACCCTCATGTCA
GGCTGGCTCATCTGA

Upstream 100 bases:

>100_bases
CCTACTGGCTGAACGCAGGCGCCGAAGGCAAGAGCACACTCAATGGCAAGGAAATTGATGTGCGCTCCAGCTATGTGGTC
ACCTTCGAGGCCCTGCCTCT

Downstream 100 bases:

>100_bases
CCTTGGGGCAGGGCGCTCTGCGGCTGCGTCAGCGTGGGTGAATATCCATCTGACACCCAGGCTGACGAAATAATACCCTG
TAAAATATAGATATATAAAT

Product: ApbE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSGANLIIPDDFGRGDITPRPDAFMGQRLTGETMGTTWSASWCAAPGLSEERVKAALEANFAAIISSMSPWEPASLISQF
NRLPRGGSLAIDTAFAEVMAMALEVADASGGAFDPCLGGAVMRRGFGPAGIGAGQEGRAHGPAVWSQLLPEPVRLYQPGG
VTLDLNAVAKGYAVDQMGRVLEGLGLTQFLVEIGGEFTARGVKPDRSPWWVDLENPSPQEAPWRLALVGHGVATSGDYRQ
QVVQNCLKVSHIVPAMTRQCSQLDLACVTVVHDNCALADAWATALFAMGDTASLTLANRLNLPILLQYRDAPARASTLMS
GWLI

Sequences:

>Translated_324_residues
MSGANLIIPDDFGRGDITPRPDAFMGQRLTGETMGTTWSASWCAAPGLSEERVKAALEANFAAIISSMSPWEPASLISQF
NRLPRGGSLAIDTAFAEVMAMALEVADASGGAFDPCLGGAVMRRGFGPAGIGAGQEGRAHGPAVWSQLLPEPVRLYQPGG
VTLDLNAVAKGYAVDQMGRVLEGLGLTQFLVEIGGEFTARGVKPDRSPWWVDLENPSPQEAPWRLALVGHGVATSGDYRQ
QVVQNCLKVSHIVPAMTRQCSQLDLACVTVVHDNCALADAWATALFAMGDTASLTLANRLNLPILLQYRDAPARASTLMS
GWLI
>Mature_323_residues
SGANLIIPDDFGRGDITPRPDAFMGQRLTGETMGTTWSASWCAAPGLSEERVKAALEANFAAIISSMSPWEPASLISQFN
RLPRGGSLAIDTAFAEVMAMALEVADASGGAFDPCLGGAVMRRGFGPAGIGAGQEGRAHGPAVWSQLLPEPVRLYQPGGV
TLDLNAVAKGYAVDQMGRVLEGLGLTQFLVEIGGEFTARGVKPDRSPWWVDLENPSPQEAPWRLALVGHGVATSGDYRQQ
VVQNCLKVSHIVPAMTRQCSQLDLACVTVVHDNCALADAWATALFAMGDTASLTLANRLNLPILLQYRDAPARASTLMSG
WLI

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=293, Percent_Identity=27.3037542662116, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34347; Mature: 34215

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGANLIIPDDFGRGDITPRPDAFMGQRLTGETMGTTWSASWCAAPGLSEERVKAALEAN
CCCCCEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHH
FAAIISSMSPWEPASLISQFNRLPRGGSLAIDTAFAEVMAMALEVADASGGAFDPCLGGA
HHHHHHCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VMRRGFGPAGIGAGQEGRAHGPAVWSQLLPEPVRLYQPGGVTLDLNAVAKGYAVDQMGRV
HHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCEEEHHHHHCCHHHHHHHHH
LEGLGLTQFLVEIGGEFTARGVKPDRSPWWVDLENPSPQEAPWRLALVGHGVATSGDYRQ
HHHCCHHHHHHHHCCCCEECCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCHHHH
QVVQNCLKVSHIVPAMTRQCSQLDLACVTVVHDNCALADAWATALFAMGDTASLTLANRL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCC
NLPILLQYRDAPARASTLMSGWLI
CCCEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SGANLIIPDDFGRGDITPRPDAFMGQRLTGETMGTTWSASWCAAPGLSEERVKAALEAN
CCCCEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHH
FAAIISSMSPWEPASLISQFNRLPRGGSLAIDTAFAEVMAMALEVADASGGAFDPCLGGA
HHHHHHCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VMRRGFGPAGIGAGQEGRAHGPAVWSQLLPEPVRLYQPGGVTLDLNAVAKGYAVDQMGRV
HHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCEEEHHHHHCCHHHHHHHHH
LEGLGLTQFLVEIGGEFTARGVKPDRSPWWVDLENPSPQEAPWRLALVGHGVATSGDYRQ
HHHCCHHHHHHHHCCCCEECCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCHHHH
QVVQNCLKVSHIVPAMTRQCSQLDLACVTVVHDNCALADAWATALFAMGDTASLTLANRL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCC
NLPILLQYRDAPARASTLMSGWLI
CCCEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]