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The map label for this gene is mntH [H]

Identifier: 114799474

GI number: 114799474

Start: 2208621

End: 2209835

Strand: Reverse

Name: mntH [H]

Synonym: HNE_2126

Alternate gene names: 114799474

Gene position: 2209835-2208621 (Counterclockwise)

Preceding gene: 114800249

Following gene: 114797321

Centisome position: 59.64

GC content: 66.83

Gene sequence:

>1215_bases
ATGACGCGCAAATTCTCCATTGGTCCGGGCGCGCTGGTTGCTGCCGCCTTCATTGGTCCGGGTACGGTGACGGCCTGCAC
GCTTGCCGGGGCCAATTTCGGCTTTGCCCTCGTCTGGGCGCTGGTCTTTGCCACATTCGCGACAATCATCCTGCAGGAGA
TGACCGTGCGTCTGGGCATCCTTGGGGGCGCGGGGCTGGGGGAGGCGCTGGTCGCGCCGGGTACGCCGGCGGCGCTCAAA
TGGGGCGCCATCGTGCTGGTACTGGCCGCGCTGGCGCTGGGCAACGCTGCCTATGAGGCCGGCAACATCACGGGGGGAGC
CCTCGGCATGCGCGCCATCCTGGGGGAAGGAGAGGGCATTCAGCGCATCACGGCGCTCGCAACGGGCCTCCTCGCGGCGC
TGATTTTGCTGCTCGGGCGGTACAAGACCCTTGAGCGCGTCCTGATCGGTCTCGTCCTCCTGATGAGCCTCGCCTTTGCC
GCCAGTCTCGTGCTCGTAAGGCCCGACATCGGCTCCATGATCGGCGGCCTGCGCCCCACGCTGCCCGATGGCAGCCTGCT
GACGGCCATGGCGCTGATCGGGACAACCATCGTGCCGTATAATCTGTTTCTCCATGCGGCGGCTGTCCGCGAACGCTGGA
AGGAAAACACAGAAGCCGGCCTCAACGCCGCCATCGCCGACACGCGCGTGTCGGTTGGCCTTGGCGGCCTGATTTCCATC
CTTGTGCTGAGCACGGCAGCCGCCAGCCTCTTTGGCGCAGGCATGGTGATCTCCAGCGGGGCGGACATGGCCTCGGCGCT
GGAACCTGCCTATGGGTCTGCGGCGCGCATCCTGGCGGGCGCCGGGCTTTGCGCGGCGGGGCTCTCCTCCGCGATCACCG
CGCCGCTGGCAACGGCGTATGCCGTATGTGAAGTGACGGGCCGGCCCAAGTCGGGCTGGTTCTTCAAGGGCATTGCGCTC
GCCATCGTGTTCATCGGCCTGAGCGTGGCGCTGCTGGGTATCCGGCCGGTGGAGCTGATCCTGATTGCGCAGGTCGCCAA
CGGCCTCCTGCTGCCCGTCGTGGCTGCCTTTCTGCTCATCACCATGAACCGAAAATCGGTACTCGGCAGCCATACCAACG
GGCCGGTGCGCAACGCGCTCGGCGTCCTTGTTGTTCTGGTCGCAGCGTTCCTCGGGCTCCGCCTCATCCTGCGCGCGCTG
GGCATCTGGCCATGA

Upstream 100 bases:

>100_bases
AAACCGGCGTCGCCTCGGTCAGTGAAGAGCATTATGCCGGCAGCCACTGGCTCGCCAGCTTCGCCACCTATCTGGAAACC
CGCCGGGGCCTCTCCGCCGA

Downstream 100 bases:

>100_bases
CGCGCAGCATCTGCCTCAATGCAGATATCGGCGAGCTTCCCGGCGAAGCGGGCAGGGCGCTCGACCATGCGATCCTGGAT
GTTGTTTCCCGGTGCAGCAT

Product: Mn2+/Fe2+ transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTRKFSIGPGALVAAAFIGPGTVTACTLAGANFGFALVWALVFATFATIILQEMTVRLGILGGAGLGEALVAPGTPAALK
WGAIVLVLAALALGNAAYEAGNITGGALGMRAILGEGEGIQRITALATGLLAALILLLGRYKTLERVLIGLVLLMSLAFA
ASLVLVRPDIGSMIGGLRPTLPDGSLLTAMALIGTTIVPYNLFLHAAAVRERWKENTEAGLNAAIADTRVSVGLGGLISI
LVLSTAAASLFGAGMVISSGADMASALEPAYGSAARILAGAGLCAAGLSSAITAPLATAYAVCEVTGRPKSGWFFKGIAL
AIVFIGLSVALLGIRPVELILIAQVANGLLLPVVAAFLLITMNRKSVLGSHTNGPVRNALGVLVVLVAAFLGLRLILRAL
GIWP

Sequences:

>Translated_404_residues
MTRKFSIGPGALVAAAFIGPGTVTACTLAGANFGFALVWALVFATFATIILQEMTVRLGILGGAGLGEALVAPGTPAALK
WGAIVLVLAALALGNAAYEAGNITGGALGMRAILGEGEGIQRITALATGLLAALILLLGRYKTLERVLIGLVLLMSLAFA
ASLVLVRPDIGSMIGGLRPTLPDGSLLTAMALIGTTIVPYNLFLHAAAVRERWKENTEAGLNAAIADTRVSVGLGGLISI
LVLSTAAASLFGAGMVISSGADMASALEPAYGSAARILAGAGLCAAGLSSAITAPLATAYAVCEVTGRPKSGWFFKGIAL
AIVFIGLSVALLGIRPVELILIAQVANGLLLPVVAAFLLITMNRKSVLGSHTNGPVRNALGVLVVLVAAFLGLRLILRAL
GIWP
>Mature_403_residues
TRKFSIGPGALVAAAFIGPGTVTACTLAGANFGFALVWALVFATFATIILQEMTVRLGILGGAGLGEALVAPGTPAALKW
GAIVLVLAALALGNAAYEAGNITGGALGMRAILGEGEGIQRITALATGLLAALILLLGRYKTLERVLIGLVLLMSLAFAA
SLVLVRPDIGSMIGGLRPTLPDGSLLTAMALIGTTIVPYNLFLHAAAVRERWKENTEAGLNAAIADTRVSVGLGGLISIL
VLSTAAASLFGAGMVISSGADMASALEPAYGSAARILAGAGLCAAGLSSAITAPLATAYAVCEVTGRPKSGWFFKGIALA
IVFIGLSVALLGIRPVELILIAQVANGLLLPVVAAFLLITMNRKSVLGSHTNGPVRNALGVLVVLVAAFLGLRLILRALG
IWP

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=213, Percent_Identity=32.3943661971831, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1788736, Length=393, Percent_Identity=27.735368956743, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71993856, Length=213, Percent_Identity=28.169014084507, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210616, Length=331, Percent_Identity=25.6797583081571, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17569473, Length=291, Percent_Identity=24.3986254295533, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71999499, Length=265, Percent_Identity=27.1698113207547, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24648607, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362176, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648609, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45553443, Length=346, Percent_Identity=23.4104046242775, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 40816; Mature: 40685

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKFSIGPGALVAAAFIGPGTVTACTLAGANFGFALVWALVFATFATIILQEMTVRLGI
CCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LGGAGLGEALVAPGTPAALKWGAIVLVLAALALGNAAYEAGNITGGALGMRAILGEGEGI
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCH
QRITALATGLLAALILLLGRYKTLERVLIGLVLLMSLAFAASLVLVRPDIGSMIGGLRPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCCC
LPDGSLLTAMALIGTTIVPYNLFLHAAAVRERWKENTEAGLNAAIADTRVSVGLGGLISI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHH
LVLSTAAASLFGAGMVISSGADMASALEPAYGSAARILAGAGLCAAGLSSAITAPLATAY
HHHHHHHHHHHHCCHHEECCCHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
AVCEVTGRPKSGWFFKGIALAIVFIGLSVALLGIRPVELILIAQVANGLLLPVVAAFLLI
HHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TMNRKSVLGSHTNGPVRNALGVLVVLVAAFLGLRLILRALGIWP
HCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRKFSIGPGALVAAAFIGPGTVTACTLAGANFGFALVWALVFATFATIILQEMTVRLGI
CCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LGGAGLGEALVAPGTPAALKWGAIVLVLAALALGNAAYEAGNITGGALGMRAILGEGEGI
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCH
QRITALATGLLAALILLLGRYKTLERVLIGLVLLMSLAFAASLVLVRPDIGSMIGGLRPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCCC
LPDGSLLTAMALIGTTIVPYNLFLHAAAVRERWKENTEAGLNAAIADTRVSVGLGGLISI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHH
LVLSTAAASLFGAGMVISSGADMASALEPAYGSAARILAGAGLCAAGLSSAITAPLATAY
HHHHHHHHHHHHCCHHEECCCHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
AVCEVTGRPKSGWFFKGIALAIVFIGLSVALLGIRPVELILIAQVANGLLLPVVAAFLLI
HHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TMNRKSVLGSHTNGPVRNALGVLVVLVAAFLGLRLILRALGIWP
HCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]