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The map label for this gene is ctaD [H]

Identifier: 114799015

GI number: 114799015

Start: 1048387

End: 1050075

Strand: Direct

Name: ctaD [H]

Synonym: HNE_1039

Alternate gene names: 114799015

Gene position: 1048387-1050075 (Clockwise)

Preceding gene: 114798124

Following gene: 114798218

Centisome position: 28.3

GC content: 61.87

Gene sequence:

>1689_bases
ATGCCTATGGACGAAGTCGCCCTCGATCACGGCCACGACAGCCACGATCACAAACCCGGCTTTTTTACCCGCTGGTTCTT
CTCAACGAACCACAAGGACATCGGTACGCTGTACCTGATCTTCGCGCTCATCGCGGGTGTCGTCGGTTATTCGCTGTCCG
GCCTCATCCGTTGGGAGCTTGCCGCTCCCGGCATTGGCCCGATGCTGTGGATTCAGACCACCTTCTTCGGCCTTGAGGGC
GATGCCGCCGTCGCGGCTGCCAAACACTTCTACAACGTCGTGATCACCTATCACGGCCTCGTCATGATCTTCTTCATGGT
GATGCCCGCGCTGATCGGCGGTTTCGGCAACTGGTTCGTGCCGCTGATGATCGGCGCGCCGGACATGGCCTTCCCGCGGA
TGAACAACATCTCGTTCTGGCTCACGGTTGCGGCCTTCATCCTCGCGGTGCTGTCGATGACGGTTCCGGGCGGCTCCGCC
GGCAACGGCTTCGGTGGCGGCTGGACCCTCTATCCGCCGCTTTCCGGCTCGACCGGCCACCCCGGCCCGTCGATGGACCT
CTTGATCCTGTCGCTGCACACCGCCGGTATCGCGTCCATCCTCGGCGCCATCAACTTCATCGTCACCATCCTGAACATGC
GCGCACCCGGCATGACGCTGCATAAGATGCCGCTGTTCGCCTGGGGCATGCTGATCACTGCCGTCCTGCTGCTTCTGGCT
CTGCCAGTGCTCGCCGGCGCGCTCACCATGCTGCTGACCGACCGTAACTTCGGCTCGCAATTCTTCGTGCCAGCGGGCGG
CGGCGACCCCGTGATGTTCCAGCATCTCTTCTGGTTCTTCGGCCACCCCGAAGTGTACATCATGATCCTGCCGGCCTTCG
GCATCGTCAGCCACATCGTGTCGACCTTCTCGAAAAAGCCGATCTTCGGTTATCTCGGCATGGCCTACGCCATGGTGTCG
ATCGGCGTCATCGGCTTCGTCGTGTGGGCCCACCACATGTACACCGTCGGCATGAACGTTGACCTGAAAGCCTACTTCGT
GGCGGCCACCATGGTCATCGCGGTCCCCACCGGCATCAAGATCTTCTCCTGGATCGCGACGATGTGGGGCGGCTCGATCG
ACTTCAAACTGCCCATGCTCTGGGCCATCGGCTTCATCTTCCTGTTCACACTGGGCGGTGTCACAGGTGTGGTTCTGGCC
AACGCCGGTGTCGACCATGCCCTCCACGACACCTATTACGTGGTGGCCCACTTCCACTACGTGCTGTCGCTCGGCGCCGT
GTTCGGCCTCTTCGCGGGCTGGTACTACTGGTTCGAGAAGATGTTCGGCATCAAGTACAACAGCTTCCTGGGCGGCCTGC
ACTTCTGGCTGATGTTCATCGGCTCGAACCTCCTGTTCTTCCCGCAGCACTTCCTGGGTCTGCAGGGCATGCCGCGCCGT
TACATCGACTATGCAGACGGCTTCGCCACCTGGCACCACTGGTCGTCGATCGGCTACGCGGTCACCCTCGTTGCCACCCT
GATCTTCTTCTTCTCGCTGGCCGTTGCCTTCATCCAGCGCCGCAAGGCGGATGAAAGCGGCAACCCCTGGGGCGAAGGCG
CCACGACGCTGGAATGGACCCTGCCGTCGCCGCCACCCTTCCACCAGTATAACGAACTGCCGGTGGTCAACACCAAGGGC
GGCCACTAG

Upstream 100 bases:

>100_bases
GAGACTTTGACGGCGCTGCCGCGTCGGTCCGCCAGATTGCCTCGGCTGACGCCGGCGCTAAATTCGCTTCTAACTAGTTC
CGAGAGAAAGAGCCTTTCCC

Downstream 100 bases:

>100_bases
GCACCGATCAGGCCCGCCGCACCGGGCTGGAGAATTGAACCAACCGGGGCGGCCCTCGCGCATCAGCGTGCGGGCCGCTT
CGTTTAAAACGGCCTGAGAG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MPMDEVALDHGHDSHDHKPGFFTRWFFSTNHKDIGTLYLIFALIAGVVGYSLSGLIRWELAAPGIGPMLWIQTTFFGLEG
DAAVAAAKHFYNVVITYHGLVMIFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAAFILAVLSMTVPGGSA
GNGFGGGWTLYPPLSGSTGHPGPSMDLLILSLHTAGIASILGAINFIVTILNMRAPGMTLHKMPLFAWGMLITAVLLLLA
LPVLAGALTMLLTDRNFGSQFFVPAGGGDPVMFQHLFWFFGHPEVYIMILPAFGIVSHIVSTFSKKPIFGYLGMAYAMVS
IGVIGFVVWAHHMYTVGMNVDLKAYFVAATMVIAVPTGIKIFSWIATMWGGSIDFKLPMLWAIGFIFLFTLGGVTGVVLA
NAGVDHALHDTYYVVAHFHYVLSLGAVFGLFAGWYYWFEKMFGIKYNSFLGGLHFWLMFIGSNLLFFPQHFLGLQGMPRR
YIDYADGFATWHHWSSIGYAVTLVATLIFFFSLAVAFIQRRKADESGNPWGEGATTLEWTLPSPPPFHQYNELPVVNTKG
GH

Sequences:

>Translated_562_residues
MPMDEVALDHGHDSHDHKPGFFTRWFFSTNHKDIGTLYLIFALIAGVVGYSLSGLIRWELAAPGIGPMLWIQTTFFGLEG
DAAVAAAKHFYNVVITYHGLVMIFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAAFILAVLSMTVPGGSA
GNGFGGGWTLYPPLSGSTGHPGPSMDLLILSLHTAGIASILGAINFIVTILNMRAPGMTLHKMPLFAWGMLITAVLLLLA
LPVLAGALTMLLTDRNFGSQFFVPAGGGDPVMFQHLFWFFGHPEVYIMILPAFGIVSHIVSTFSKKPIFGYLGMAYAMVS
IGVIGFVVWAHHMYTVGMNVDLKAYFVAATMVIAVPTGIKIFSWIATMWGGSIDFKLPMLWAIGFIFLFTLGGVTGVVLA
NAGVDHALHDTYYVVAHFHYVLSLGAVFGLFAGWYYWFEKMFGIKYNSFLGGLHFWLMFIGSNLLFFPQHFLGLQGMPRR
YIDYADGFATWHHWSSIGYAVTLVATLIFFFSLAVAFIQRRKADESGNPWGEGATTLEWTLPSPPPFHQYNELPVVNTKG
GH
>Mature_561_residues
PMDEVALDHGHDSHDHKPGFFTRWFFSTNHKDIGTLYLIFALIAGVVGYSLSGLIRWELAAPGIGPMLWIQTTFFGLEGD
AAVAAAKHFYNVVITYHGLVMIFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAAFILAVLSMTVPGGSAG
NGFGGGWTLYPPLSGSTGHPGPSMDLLILSLHTAGIASILGAINFIVTILNMRAPGMTLHKMPLFAWGMLITAVLLLLAL
PVLAGALTMLLTDRNFGSQFFVPAGGGDPVMFQHLFWFFGHPEVYIMILPAFGIVSHIVSTFSKKPIFGYLGMAYAMVSI
GVIGFVVWAHHMYTVGMNVDLKAYFVAATMVIAVPTGIKIFSWIATMWGGSIDFKLPMLWAIGFIFLFTLGGVTGVVLAN
AGVDHALHDTYYVVAHFHYVLSLGAVFGLFAGWYYWFEKMFGIKYNSFLGGLHFWLMFIGSNLLFFPQHFLGLQGMPRRY
IDYADGFATWHHWSSIGYAVTLVATLIFFFSLAVAFIQRRKADESGNPWGEGATTLEWTLPSPPPFHQYNELPVVNTKGG
H

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=533, Percent_Identity=57.9737335834897, Blast_Score=577, Evalue=1e-164,
Organism=Escherichia coli, GI1786634, Length=539, Percent_Identity=41.7439703153989, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6226519, Length=556, Percent_Identity=52.158273381295, Blast_Score=562, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6226524, Length=342, Percent_Identity=56.140350877193, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226523, Length=267, Percent_Identity=50.187265917603, Blast_Score=239, Evalue=8e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61797; Mature: 61666

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMDEVALDHGHDSHDHKPGFFTRWFFSTNHKDIGTLYLIFALIAGVVGYSLSGLIRWEL
CCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEE
AAPGIGPMLWIQTTFFGLEGDAAVAAAKHFYNVVITYHGLVMIFFMVMPALIGGFGNWFV
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
PLMIGAPDMAFPRMNNISFWLTVAAFILAVLSMTVPGGSAGNGFGGGWTLYPPLSGSTGH
EHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCC
PGPSMDLLILSLHTAGIASILGAINFIVTILNMRAPGMTLHKMPLFAWGMLITAVLLLLA
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
LPVLAGALTMLLTDRNFGSQFFVPAGGGDPVMFQHLFWFFGHPEVYIMILPAFGIVSHIV
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHH
STFSKKPIFGYLGMAYAMVSIGVIGFVVWAHHMYTVGMNVDLKAYFVAATMVIAVPTGIK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHH
IFSWIATMWGGSIDFKLPMLWAIGFIFLFTLGGVTGVVLANAGVDHALHDTYYVVAHFHY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHHHHH
VLSLGAVFGLFAGWYYWFEKMFGIKYNSFLGGLHFWLMFIGSNLLFFPQHFLGLQGMPRR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCHHHHCCCCCCHH
YIDYADGFATWHHWSSIGYAVTLVATLIFFFSLAVAFIQRRKADESGNPWGEGATTLEWT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
LPSPPPFHQYNELPVVNTKGGH
CCCCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure 
PMDEVALDHGHDSHDHKPGFFTRWFFSTNHKDIGTLYLIFALIAGVVGYSLSGLIRWEL
CCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEE
AAPGIGPMLWIQTTFFGLEGDAAVAAAKHFYNVVITYHGLVMIFFMVMPALIGGFGNWFV
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
PLMIGAPDMAFPRMNNISFWLTVAAFILAVLSMTVPGGSAGNGFGGGWTLYPPLSGSTGH
EHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCC
PGPSMDLLILSLHTAGIASILGAINFIVTILNMRAPGMTLHKMPLFAWGMLITAVLLLLA
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
LPVLAGALTMLLTDRNFGSQFFVPAGGGDPVMFQHLFWFFGHPEVYIMILPAFGIVSHIV
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHH
STFSKKPIFGYLGMAYAMVSIGVIGFVVWAHHMYTVGMNVDLKAYFVAATMVIAVPTGIK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHH
IFSWIATMWGGSIDFKLPMLWAIGFIFLFTLGGVTGVVLANAGVDHALHDTYYVVAHFHY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHHHHH
VLSLGAVFGLFAGWYYWFEKMFGIKYNSFLGGLHFWLMFIGSNLLFFPQHFLGLQGMPRR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCHHHHCCCCCCHH
YIDYADGFATWHHWSSIGYAVTLVATLIFFFSLAVAFIQRRKADESGNPWGEGATTLEWT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
LPSPPPFHQYNELPVVNTKGGH
CCCCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]