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The map label for this gene is coxB [H]

Identifier: 114798124

GI number: 114798124

Start: 1047395

End: 1048363

Strand: Direct

Name: coxB [H]

Synonym: HNE_1038

Alternate gene names: 114798124

Gene position: 1047395-1048363 (Clockwise)

Preceding gene: 114800536

Following gene: 114799015

Centisome position: 28.27

GC content: 62.02

Gene sequence:

>969_bases
GTGCGACACATTCTTGCCGCCCTCTCCGCTGCCTTGCTGGCCGGACCTGCCTTTGCGGCCGAGCCCGTAGATGGCGCGAT
CAATATGCAACCCGCTGCGACCCGAATCGCTGAGCGTGTGCATGACTTCCACAATGTGCTGCTGGTGATCATCACGGCCA
TCACGCTGCTGGTACTGGCGCTGATCATCTGGATCGTGGTGCGCTACAACCAGAAGGCCAACAAGGTCTCCCGCAAGTTC
AGCCACAACACCATGATCGAAGTGGTGTGGACGGTTGTGCCGGCGCTGATCCTGGTCGGCATTGCGGGCCTGTCCTTCCC
GAACCTCTACTATCAGAACGTCACGCCGAATCTCGGCCAGATCGTCGCCACCTCCAAACAGCTGCTGGCAGACGGCAAAT
CCGCCGAGCATCAGGCCTACACCCAGAACTACTTCCCTGATGCGGCCGAAGAAGGCTTCATCAACGTCAAGATCCAGGGC
AACCAGTGGAACTGGACCTACACCTATGCCGACATCGTCGATGACGCCGGCATCCCGGTCGAGTTCGTGTCCAACGGTCT
CCACAAAGGCACCTCGCGCGACGCCGATGCTCCGGCCGGCGCCCTGCGCCTCCTGGCCACCGACTATCCGATGGTCGTGC
CCGAAGACCGCTATGTCCGCTTCTACACCGCCGCCGCTGACGTGATCCACTCCTGGGCCGTCCCGTCCTTCGCCGTGAAG
GTCGATGCCATCCCCGGCCGCCTCAACGAGGGCTGGTTCCTCGTCAAGGAGCCGGGCGTCTATTACGGTCAGTGTTCCGA
GCTTTGCGGTGTCGACCACGCCTTCATGCCGATCGAGGTCCGCGTCGTTTCACAGGCACAGTTTGACGCCTGGGCCGAGA
TGATGAAGGCCGGAGACTTTGACGGCGCTGCCGCGTCGGTCCGCCAGATTGCCTCGGCTGACGCCGGCGCTAAATTCGCT
TCTAACTAG

Upstream 100 bases:

>100_bases
GGGCGATGCGCTGCGACAATTTTGAGCGCGGAAAACGCTGGGGTTCCCGGCGCGGCTGGTATAGTTAGAGGCCAAATTGA
GACGAATTGGGGTTGAATCC

Downstream 100 bases:

>100_bases
TTCCGAGAGAAAGAGCCTTTCCCATGCCTATGGACGAAGTCGCCCTCGATCACGGCCACGACAGCCACGATCACAAACCC
GGCTTTTTTACCCGCTGGTT

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRHILAALSAALLAGPAFAAEPVDGAINMQPAATRIAERVHDFHNVLLVIITAITLLVLALIIWIVVRYNQKANKVSRKF
SHNTMIEVVWTVVPALILVGIAGLSFPNLYYQNVTPNLGQIVATSKQLLADGKSAEHQAYTQNYFPDAAEEGFINVKIQG
NQWNWTYTYADIVDDAGIPVEFVSNGLHKGTSRDADAPAGALRLLATDYPMVVPEDRYVRFYTAAADVIHSWAVPSFAVK
VDAIPGRLNEGWFLVKEPGVYYGQCSELCGVDHAFMPIEVRVVSQAQFDAWAEMMKAGDFDGAAASVRQIASADAGAKFA
SN

Sequences:

>Translated_322_residues
MRHILAALSAALLAGPAFAAEPVDGAINMQPAATRIAERVHDFHNVLLVIITAITLLVLALIIWIVVRYNQKANKVSRKF
SHNTMIEVVWTVVPALILVGIAGLSFPNLYYQNVTPNLGQIVATSKQLLADGKSAEHQAYTQNYFPDAAEEGFINVKIQG
NQWNWTYTYADIVDDAGIPVEFVSNGLHKGTSRDADAPAGALRLLATDYPMVVPEDRYVRFYTAAADVIHSWAVPSFAVK
VDAIPGRLNEGWFLVKEPGVYYGQCSELCGVDHAFMPIEVRVVSQAQFDAWAEMMKAGDFDGAAASVRQIASADAGAKFA
SN
>Mature_322_residues
MRHILAALSAALLAGPAFAAEPVDGAINMQPAATRIAERVHDFHNVLLVIITAITLLVLALIIWIVVRYNQKANKVSRKF
SHNTMIEVVWTVVPALILVGIAGLSFPNLYYQNVTPNLGQIVATSKQLLADGKSAEHQAYTQNYFPDAAEEGFINVKIQG
NQWNWTYTYADIVDDAGIPVEFVSNGLHKGTSRDADAPAGALRLLATDYPMVVPEDRYVRFYTAAADVIHSWAVPSFAVK
VDAIPGRLNEGWFLVKEPGVYYGQCSELCGVDHAFMPIEVRVVSQAQFDAWAEMMKAGDFDGAAASVRQIASADAGAKFA
SN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=267, Percent_Identity=32.2097378277154, Blast_Score=131, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6226540, Length=271, Percent_Identity=36.5313653136531, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35038; Mature: 35038

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHILAALSAALLAGPAFAAEPVDGAINMQPAATRIAERVHDFHNVLLVIITAITLLVLA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIIWIVVRYNQKANKVSRKFSHNTMIEVVWTVVPALILVGIAGLSFPNLYYQNVTPNLGQ
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHH
IVATSKQLLADGKSAEHQAYTQNYFPDAAEEGFINVKIQGNQWNWTYTYADIVDDAGIPV
HHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEEHHHHCCCCCCH
EFVSNGLHKGTSRDADAPAGALRLLATDYPMVVPEDRYVRFYTAAADVIHSWAVPSFAVK
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCEEEEEHHHHHHHHHHCCCCEEEE
VDAIPGRLNEGWFLVKEPGVYYGQCSELCGVDHAFMPIEVRVVSQAQFDAWAEMMKAGDF
EECCCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCC
DGAAASVRQIASADAGAKFASN
CHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRHILAALSAALLAGPAFAAEPVDGAINMQPAATRIAERVHDFHNVLLVIITAITLLVLA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIIWIVVRYNQKANKVSRKFSHNTMIEVVWTVVPALILVGIAGLSFPNLYYQNVTPNLGQ
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHH
IVATSKQLLADGKSAEHQAYTQNYFPDAAEEGFINVKIQGNQWNWTYTYADIVDDAGIPV
HHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEEHHHHCCCCCCH
EFVSNGLHKGTSRDADAPAGALRLLATDYPMVVPEDRYVRFYTAAADVIHSWAVPSFAVK
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCEEEEEHHHHHHHHHHCCCCEEEE
VDAIPGRLNEGWFLVKEPGVYYGQCSELCGVDHAFMPIEVRVVSQAQFDAWAEMMKAGDF
EECCCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCC
DGAAASVRQIASADAGAKFASN
CHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA