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The map label for this gene is gap [H]

Identifier: 114798520

GI number: 114798520

Start: 3355564

End: 3356574

Strand: Direct

Name: gap [H]

Synonym: HNE_3179

Alternate gene names: 114798520

Gene position: 3355564-3356574 (Clockwise)

Preceding gene: 114799915

Following gene: 114799328

Centisome position: 90.57

GC content: 60.04

Gene sequence:

>1011_bases
ATGACCGTTCGTGTTGCCATCAACGGATTCGGCCGCATCGGCCGCCTGGTTCTGCGCTCGATCATCGAACATGGCCGGAC
TGATATTGAAGTCGTGGCCATTAATGATCTGGGGCCGGTTGAAACCAACGCCCACCTGCTGCGTTTCGATTCGGTACATG
GCCGTTTCCCGGCAGATGTGAAAGTTGACGGTGACAAGATCGTCATCAACGGCAAGCCAATCCTGGTGACCGCGATCCGC
GATCCCAAGGACCTGCCCCACCGCGAGCTTGACGTCGACATCGCGATGGAATGCACCGGCATCTTCACCTCGAAGGACAA
GGCCGAGGCCCACCTCGCCGCCGGCGCCAAGCGCGTGCTGGTCTCTGCCCCCGCAGACGGCGCAGACCTGACCGTCGTTT
ATGGCGTCAACCACGACAAGCTCAAGAAAGAGCACATGGTCGTCTCCAACGCCTCGTGCACCACCAACTGCCTTGCTCCC
GTGGCCTTCGTCCTGAACAAGGCCGTGGGCATCGACAAGGGCATGATGACGACGATCCATTCGTACACGAATGACCAGCC
TTCGCTCGACCAGATGCACAAGGACCTCTACCGGGCCCGCGCCGCGTCTCTCTCGATGATCCCGACCTCGACCGGCGCCG
CCAAGGCTGTCGGCCTCGTGCTGCCGGAACTCAAGGGCAAGCTGGACGGCATCTCCGTGCGCGTGCCAACGCCGAACGTT
TCGCTGGTTGACCTGAAATTCATCGCCAAGAAATCCACCACAGCCGAAGAGATCAACGCAGCGATCATCGCGGCGGCAGA
CGCTGGCCCGCTGAAAGGCATCCTTGGCTACACGGACGTCCCCAACGTGTCGTCAGACTTCATCCATGACGACCGTTCCT
CGATCTTCCACCTTGACCAGACCAAAGTCATGGACGGCAATTTCGTCTCGATCATGACCTGGTATGACAATGAGTGGGGT
TTCTCGACCCGCATGGCCGACACCGCCATTGCGATCGCGAAGCTGATCTGA

Upstream 100 bases:

>100_bases
TCGCGTCGCAGTACCGCACCGTGCGGGGTGGACGTGACCGGCACACCCATTTAAAGGGGCGCAAGCCTGTGAATTTGCTC
GCCCAAGAGGAGAAATAAAG

Downstream 100 bases:

>100_bases
AAACCCCTCCCCCGCCGCTCGCTCCTGCGCGATGGCGGGGGCCCCAGCGGCGGCATTTCATCAGACCTCACGCGCCCTCC
GCATTCGCGCCGGGGGACAC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTVRVAINGFGRIGRLVLRSIIEHGRTDIEVVAINDLGPVETNAHLLRFDSVHGRFPADVKVDGDKIVINGKPILVTAIR
DPKDLPHRELDVDIAMECTGIFTSKDKAEAHLAAGAKRVLVSAPADGADLTVVYGVNHDKLKKEHMVVSNASCTTNCLAP
VAFVLNKAVGIDKGMMTTIHSYTNDQPSLDQMHKDLYRARAASLSMIPTSTGAAKAVGLVLPELKGKLDGISVRVPTPNV
SLVDLKFIAKKSTTAEEINAAIIAAADAGPLKGILGYTDVPNVSSDFIHDDRSSIFHLDQTKVMDGNFVSIMTWYDNEWG
FSTRMADTAIAIAKLI

Sequences:

>Translated_336_residues
MTVRVAINGFGRIGRLVLRSIIEHGRTDIEVVAINDLGPVETNAHLLRFDSVHGRFPADVKVDGDKIVINGKPILVTAIR
DPKDLPHRELDVDIAMECTGIFTSKDKAEAHLAAGAKRVLVSAPADGADLTVVYGVNHDKLKKEHMVVSNASCTTNCLAP
VAFVLNKAVGIDKGMMTTIHSYTNDQPSLDQMHKDLYRARAASLSMIPTSTGAAKAVGLVLPELKGKLDGISVRVPTPNV
SLVDLKFIAKKSTTAEEINAAIIAAADAGPLKGILGYTDVPNVSSDFIHDDRSSIFHLDQTKVMDGNFVSIMTWYDNEWG
FSTRMADTAIAIAKLI
>Mature_335_residues
TVRVAINGFGRIGRLVLRSIIEHGRTDIEVVAINDLGPVETNAHLLRFDSVHGRFPADVKVDGDKIVINGKPILVTAIRD
PKDLPHRELDVDIAMECTGIFTSKDKAEAHLAAGAKRVLVSAPADGADLTVVYGVNHDKLKKEHMVVSNASCTTNCLAPV
AFVLNKAVGIDKGMMTTIHSYTNDQPSLDQMHKDLYRARAASLSMIPTSTGAAKAVGLVLPELKGKLDGISVRVPTPNVS
LVDLKFIAKKSTTAEEINAAIIAAADAGPLKGILGYTDVPNVSSDFIHDDRSSIFHLDQTKVMDGNFVSIMTWYDNEWGF
STRMADTAIAIAKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=46.7889908256881, Blast_Score=285, Evalue=3e-77,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=45.2599388379205, Blast_Score=272, Evalue=3e-73,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=48.0712166172107, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=48.6567164179104, Blast_Score=308, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=47.7341389728097, Blast_Score=286, Evalue=9e-78,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=47.4320241691843, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=46.8842729970326, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=46.8842729970326, Blast_Score=278, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=50.5952380952381, Blast_Score=312, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=49.702380952381, Blast_Score=312, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=49.702380952381, Blast_Score=311, Evalue=1e-85,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=48.4662576687117, Blast_Score=290, Evalue=7e-79,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=48.4662576687117, Blast_Score=290, Evalue=7e-79,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=47.8527607361963, Blast_Score=287, Evalue=8e-78,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=47.8527607361963, Blast_Score=287, Evalue=8e-78,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=43.558282208589, Blast_Score=257, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36190; Mature: 36059

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVAINGFGRIGRLVLRSIIEHGRTDIEVVAINDLGPVETNAHLLRFDSVHGRFPADV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCE
KVDGDKIVINGKPILVTAIRDPKDLPHRELDVDIAMECTGIFTSKDKAEAHLAAGAKRVL
EECCCEEEECCCEEEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCEEEE
VSAPADGADLTVVYGVNHDKLKKEHMVVSNASCTTNCLAPVAFVLNKAVGIDKGMMTTIH
EECCCCCCCEEEEEECCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
SYTNDQPSLDQMHKDLYRARAASLSMIPTSTGAAKAVGLVLPELKGKLDGISVRVPTPNV
HCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHEECHHHCCCCCCEEEEECCCCC
SLVDLKFIAKKSTTAEEINAAIIAAADAGPLKGILGYTDVPNVSSDFIHDDRSSIFHLDQ
EEEEEEEEECCCCCHHHCCEEEEEECCCCCCCHHCCCCCCCCCCHHHHCCCCHHEEEECC
TKVMDGNFVSIMTWYDNEWGFSTRMADTAIAIAKLI
CEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVRVAINGFGRIGRLVLRSIIEHGRTDIEVVAINDLGPVETNAHLLRFDSVHGRFPADV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCE
KVDGDKIVINGKPILVTAIRDPKDLPHRELDVDIAMECTGIFTSKDKAEAHLAAGAKRVL
EECCCEEEECCCEEEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCEEEE
VSAPADGADLTVVYGVNHDKLKKEHMVVSNASCTTNCLAPVAFVLNKAVGIDKGMMTTIH
EECCCCCCCEEEEEECCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
SYTNDQPSLDQMHKDLYRARAASLSMIPTSTGAAKAVGLVLPELKGKLDGISVRVPTPNV
HCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHEECHHHCCCCCCEEEEECCCCC
SLVDLKFIAKKSTTAEEINAAIIAAADAGPLKGILGYTDVPNVSSDFIHDDRSSIFHLDQ
EEEEEEEEECCCCCHHHCCEEEEEECCCCCCCHHCCCCCCCCCCHHHHCCCCHHEEEECC
TKVMDGNFVSIMTWYDNEWGFSTRMADTAIAIAKLI
CEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]