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The map label for this gene is hsdM [C]

Identifier: 114798203

GI number: 114798203

Start: 2694637

End: 2696178

Strand: Reverse

Name: hsdM [C]

Synonym: HNE_2542

Alternate gene names: 114798203

Gene position: 2696178-2694637 (Counterclockwise)

Preceding gene: 114798978

Following gene: 114798271

Centisome position: 72.77

GC content: 60.31

Gene sequence:

>1542_bases
ATGCTCACCGGCGACATCCGTATCAAGGTCGATCAAATCTGGAATGCCTTCTGGTCAGGGGGCGTATCGAACCCGCTCTC
CGTGATCGAGCAGATCACCTATCTTCTTTTCATCAAGCGGCTAGATGATCTCCACACCCTGGAGGAAAACAAGGCGGCCA
ATCTCGGCATCAAGATGGAGCGCCGTATCTTCCCAGACGGGAAAGATGATCAAGGGCGTGACTGGTCAGACCTGCGCTGG
TCGCGGTTCAAGAACTTTGAAGCCCGCGCCATGATGGACGTGGTGGCGGAGCGTGTCTTCCCCTTCCTGCGCCAGATGGG
GGAGGAGGGCTCCAGTTACGGCGAGCACATGCGTGATGCGCGCCTTGGCTTTTCCAACGCCGCGCTGCTCGCGAAGGCCG
TCGATTTGCTCGATAAAATCCCGATGGATGATCGCGACACCAAGGGGGATCTCTACGAATACATGCTCGGCAAGATCGCG
AGTGCAGGGCAGAACGGCCAGTTCCGCACTCCGCGCCACATCATCCAGCTGATGGTCGAGATGACGCAGCCAACCCCGCA
AGATGTGATCTGCGATCCGGCAGCGGGAACGTGCGGCTTCCTTGTCGCGGCGGGCGAGTATCTGCGGGAGAAGCATGCAT
CGCTTTTCCGGCACGAAAAGCAGCGTACGCACTTCCACAACGGCATGTTCCACGGGTTCGACTTCGACCCGACCATGCTC
CGCATTGGTTCTATGAACATGGTGTTGCACGGGGTTGAGAACCCCGATGTCAGCTATCGTGACAGCCTTGCACAGGAGCA
TGACGCTGATGCGGGGCGTTATTCCCTCATTCTCGCCAACCCACCGTTTGCAGGTTCGCTGGATTATGACACGACCGCGA
AAGACCTTCAGCAAATCGTCAAGACGAAGAAGACCGAGCTTCTCTTCCTCGCGCTCTTCCTGCGCCTTCTGAAAACCGGC
GGGCGCGCGGCGGTGATCGTGCCGGACGGCGTTCTCTTCGGCTCTTCCACGGCGCACAAGACGCTGCGTGAAATGCTGGT
CGAAAAGCACAAGCTGGAGGCGGTGCTGAAACTGCCCTCCGGGGTGTTCCGGCCCTATGCGGGCGTCTCTACCGCGATCC
TCTTCTTCACAAAGACCGGCGTGGGCGGCACCGATCACGTCTGGTTCTATGACCTCCAGGCCGATGGCCAGAGCCTCGAT
GACAAACGCACCGAGCTGTTGGCTCCAGAAAAACTGGGAGCGACGCCGCGCGAGGCGCTAGTCGAGGGCGAGCACGACAA
GAACAATCTACCGGACGCGCTCGCCCGCTGGTTCGCGCGCGACGCGGCTGAGCGGGAGAACCCGCGCACGGCGCAGAGCT
TCTGCGTGCCGAAGGCCGAGATCGCCGCGACCGGAACTTACGACCTCTCGCTCAACCGCTACAAGCAGGTGGAGCATGAG
GAGGTGGAGCACGAAAGCCCCGCCGCTATAATCGCCGACCTGCGCAAGCTGGAGGACGAGATAAGCAAAAGCCTCACCAA
CCTGGAGGCAATGCTGGGATGA

Upstream 100 bases:

>100_bases
CCGCAAATGGATCCCCGCGGGGATCGTGAATTCACTAAATGAATTGGGCTCGCTTAAATTGTTTTTGCGATGGTCACTAT
TTAACGAAGAATGAGGCGTA

Downstream 100 bases:

>100_bases
ATTGGCCCCTCAGAACGCTTGACGAGATTTTCGAGATCGCGCGCGGAGGCTCGCCCCGTCCGATTGACCAATTCATCACG
GATGCGGACGACGGCGTGAA

Product: type I restriction-modification system, M subunit

Products: NA

Alternate protein names: M.BthVORF4518P [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MLTGDIRIKVDQIWNAFWSGGVSNPLSVIEQITYLLFIKRLDDLHTLEENKAANLGIKMERRIFPDGKDDQGRDWSDLRW
SRFKNFEARAMMDVVAERVFPFLRQMGEEGSSYGEHMRDARLGFSNAALLAKAVDLLDKIPMDDRDTKGDLYEYMLGKIA
SAGQNGQFRTPRHIIQLMVEMTQPTPQDVICDPAAGTCGFLVAAGEYLREKHASLFRHEKQRTHFHNGMFHGFDFDPTML
RIGSMNMVLHGVENPDVSYRDSLAQEHDADAGRYSLILANPPFAGSLDYDTTAKDLQQIVKTKKTELLFLALFLRLLKTG
GRAAVIVPDGVLFGSSTAHKTLREMLVEKHKLEAVLKLPSGVFRPYAGVSTAILFFTKTGVGGTDHVWFYDLQADGQSLD
DKRTELLAPEKLGATPREALVEGEHDKNNLPDALARWFARDAAERENPRTAQSFCVPKAEIAATGTYDLSLNRYKQVEHE
EVEHESPAAIIADLRKLEDEISKSLTNLEAMLG

Sequences:

>Translated_513_residues
MLTGDIRIKVDQIWNAFWSGGVSNPLSVIEQITYLLFIKRLDDLHTLEENKAANLGIKMERRIFPDGKDDQGRDWSDLRW
SRFKNFEARAMMDVVAERVFPFLRQMGEEGSSYGEHMRDARLGFSNAALLAKAVDLLDKIPMDDRDTKGDLYEYMLGKIA
SAGQNGQFRTPRHIIQLMVEMTQPTPQDVICDPAAGTCGFLVAAGEYLREKHASLFRHEKQRTHFHNGMFHGFDFDPTML
RIGSMNMVLHGVENPDVSYRDSLAQEHDADAGRYSLILANPPFAGSLDYDTTAKDLQQIVKTKKTELLFLALFLRLLKTG
GRAAVIVPDGVLFGSSTAHKTLREMLVEKHKLEAVLKLPSGVFRPYAGVSTAILFFTKTGVGGTDHVWFYDLQADGQSLD
DKRTELLAPEKLGATPREALVEGEHDKNNLPDALARWFARDAAERENPRTAQSFCVPKAEIAATGTYDLSLNRYKQVEHE
EVEHESPAAIIADLRKLEDEISKSLTNLEAMLG
>Mature_513_residues
MLTGDIRIKVDQIWNAFWSGGVSNPLSVIEQITYLLFIKRLDDLHTLEENKAANLGIKMERRIFPDGKDDQGRDWSDLRW
SRFKNFEARAMMDVVAERVFPFLRQMGEEGSSYGEHMRDARLGFSNAALLAKAVDLLDKIPMDDRDTKGDLYEYMLGKIA
SAGQNGQFRTPRHIIQLMVEMTQPTPQDVICDPAAGTCGFLVAAGEYLREKHASLFRHEKQRTHFHNGMFHGFDFDPTML
RIGSMNMVLHGVENPDVSYRDSLAQEHDADAGRYSLILANPPFAGSLDYDTTAKDLQQIVKTKKTELLFLALFLRLLKTG
GRAAVIVPDGVLFGSSTAHKTLREMLVEKHKLEAVLKLPSGVFRPYAGVSTAILFFTKTGVGGTDHVWFYDLQADGQSLD
DKRTELLAPEKLGATPREALVEGEHDKNNLPDALARWFARDAAERENPRTAQSFCVPKAEIAATGTYDLSLNRYKQVEHE
EVEHESPAAIIADLRKLEDEISKSLTNLEAMLG

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=276, Percent_Identity=35.1449275362319, Blast_Score=138, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57588; Mature: 57588

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTGDIRIKVDQIWNAFWSGGVSNPLSVIEQITYLLFIKRLDDLHTLEENKAANLGIKME
CCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
RRIFPDGKDDQGRDWSDLRWSRFKNFEARAMMDVVAERVFPFLRQMGEEGSSYGEHMRDA
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RLGFSNAALLAKAVDLLDKIPMDDRDTKGDLYEYMLGKIASAGQNGQFRTPRHIIQLMVE
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MTQPTPQDVICDPAAGTCGFLVAAGEYLREKHASLFRHEKQRTHFHNGMFHGFDFDPTML
HCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RIGSMNMVLHGVENPDVSYRDSLAQEHDADAGRYSLILANPPFAGSLDYDTTAKDLQQIV
EECCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHH
KTKKTELLFLALFLRLLKTGGRAAVIVPDGVLFGSSTAHKTLREMLVEKHKLEAVLKLPS
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
GVFRPYAGVSTAILFFTKTGVGGTDHVWFYDLQADGQSLDDKRTELLAPEKLGATPREAL
HHCCCCCCHHHEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHCCCHHHCCCHHHHH
VEGEHDKNNLPDALARWFARDAAERENPRTAQSFCVPKAEIAATGTYDLSLNRYKQVEHE
HCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHEECCCEECCHHHHHHHHHH
EVEHESPAAIIADLRKLEDEISKSLTNLEAMLG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTGDIRIKVDQIWNAFWSGGVSNPLSVIEQITYLLFIKRLDDLHTLEENKAANLGIKME
CCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
RRIFPDGKDDQGRDWSDLRWSRFKNFEARAMMDVVAERVFPFLRQMGEEGSSYGEHMRDA
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RLGFSNAALLAKAVDLLDKIPMDDRDTKGDLYEYMLGKIASAGQNGQFRTPRHIIQLMVE
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MTQPTPQDVICDPAAGTCGFLVAAGEYLREKHASLFRHEKQRTHFHNGMFHGFDFDPTML
HCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RIGSMNMVLHGVENPDVSYRDSLAQEHDADAGRYSLILANPPFAGSLDYDTTAKDLQQIV
EECCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHH
KTKKTELLFLALFLRLLKTGGRAAVIVPDGVLFGSSTAHKTLREMLVEKHKLEAVLKLPS
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
GVFRPYAGVSTAILFFTKTGVGGTDHVWFYDLQADGQSLDDKRTELLAPEKLGATPREAL
HHCCCCCCHHHEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHCCCHHHCCCHHHHH
VEGEHDKNNLPDALARWFARDAAERENPRTAQSFCVPKAEIAATGTYDLSLNRYKQVEHE
HCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHEECCCEECCHHHHHHHHHH
EVEHESPAAIIADLRKLEDEISKSLTNLEAMLG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]