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The map label for this gene is hutF [H]

Identifier: 114798152

GI number: 114798152

Start: 2498561

End: 2499931

Strand: Reverse

Name: hutF [H]

Synonym: HNE_2394

Alternate gene names: 114798152

Gene position: 2499931-2498561 (Counterclockwise)

Preceding gene: 114798121

Following gene: 114799323

Centisome position: 67.47

GC content: 61.85

Gene sequence:

>1371_bases
GTGGCCGGGAAATCTTCAGAGCGTCTCTGGTTCGATCACGCGCTTCTGCCTTCTGGCTGGGCAAGCGGGGTGGCGATCAC
GATCGAGCGCGGGCTCATCGCAGATGTATCCGTAAATGTTGCGCCTCCTTCAGGGGCGGTTCGGGGCCGGTCTGTTCTTC
CGGGTCTGACTAATCTTCACTCCCATGCGTTCCAGAGGGCGATGTCCGGGCTGACGGAAGTTCGGGAAAATATTCAGGAC
AGTTTCTGGTCGTGGCGAACTCTACTCTATCGGTTTGTCAGCCGGATTGGGCCGGAGGATGTCCACGCGATTGCGGCGAT
GGCCTATGCGGAAATGCTCGAGGCTGGCTTCACGCGGGTCTGCGAGTTTCACTATGTCCATAATGACGAAGCGGGCGCGC
GTTACGCCGACCCGGCGGAGATGGCGGGGCAGGTGGTTCGTGCAGCGGGCGATACAGGATTGGGGCTGACGCTGCTGCCG
GTGTTCTATGCCCATTCGGGCTTTGGCGGGCAGCCGCCACTGGACGGGCAGAGGCGGTTCCTGAGTGATCTTGAGGGCTT
TGCTACGCTGATGGACGCGGCAGCAAAGCATGGTGCCAATCAGCCTGATTTTGTGTTGGGTTTTGCGCCGCACAGCCTTC
GCGCGGTGACCCGCGCCCAGCTCAAGGCATTGCTGGCGATGGACAAGGCCGGGCCTGTCCACATCCATATTGCCGAGCAG
GCGCAGGAGGTGGCGGACTGTCTGGCCTGGTCGGGCGCGCGGCCTGTGGAGTGGCTGCTGCACAATGCCGATGTCGATGC
CCGCTGGTGCCTTGTGCATGCGACGCATACGAACGACCGGGAAATCCACGGGATAGCCAAAAGCGGGGCGGTTGCGGGGT
TGTGCCCGGTGACCGAGGCGAATTTGGGTGACGGCATTTTTGATGGCCGGGGCTTTGTTTCCTATGGTGGACACTACGGC
GTTGGAACCGATTCCAATGTTTCAATTGGCGCGGCAGACGAGTTGCGGATGCTGGAATATTCCCAGCGTTTCAAGACATT
GTCTCGCAACGTCCTGACCGGTGAGGGGTTTGCCTCGACCGGGCGTTCGATGTTTGAGCACGCCCTGGCAGGCGGGGGCC
GGGCGGCGGGCATTTCTGTTGGACTGGCGCCCGGCAATCCGGCGGATATGGCCGCGATCACCGACGCGGTGCTGCCCGAA
GCGGCAATGGGGGACGACCGCTTGCTGGACGCTTGGGTGTTCCGGGCTAAAAGCGGAGCAATTTCAGATGTTTGGCGGCG
CGGTGAGCATGTCGTACAGGGCGGACACCATATTCACAGACCCGCAATCGAGGCGCGGTACAAAGCCTGCCTTGAGGCGC
TTCTGGCGTGA

Upstream 100 bases:

>100_bases
GTCCAGATCCGCTTCTTCTGCATCTCCAGGGTCCCGTTGTCTTCGCATCGGACTTCTTTTAATATGTATAGACATAATAG
AAGAGTCGGAGGGATGTCCA

Downstream 100 bases:

>100_bases
CAAAAGCCGGACAAATCTGGACAAACTTGGACAAATCGAGACAAAGCCGGACAAAACAGGACACATGCGCGACCCTTCCG
AACCCCTTTCCGTCAGCGAA

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAGKSSERLWFDHALLPSGWASGVAITIERGLIADVSVNVAPPSGAVRGRSVLPGLTNLHSHAFQRAMSGLTEVRENIQD
SFWSWRTLLYRFVSRIGPEDVHAIAAMAYAEMLEAGFTRVCEFHYVHNDEAGARYADPAEMAGQVVRAAGDTGLGLTLLP
VFYAHSGFGGQPPLDGQRRFLSDLEGFATLMDAAAKHGANQPDFVLGFAPHSLRAVTRAQLKALLAMDKAGPVHIHIAEQ
AQEVADCLAWSGARPVEWLLHNADVDARWCLVHATHTNDREIHGIAKSGAVAGLCPVTEANLGDGIFDGRGFVSYGGHYG
VGTDSNVSIGAADELRMLEYSQRFKTLSRNVLTGEGFASTGRSMFEHALAGGGRAAGISVGLAPGNPADMAAITDAVLPE
AAMGDDRLLDAWVFRAKSGAISDVWRRGEHVVQGGHHIHRPAIEARYKACLEALLA

Sequences:

>Translated_456_residues
MAGKSSERLWFDHALLPSGWASGVAITIERGLIADVSVNVAPPSGAVRGRSVLPGLTNLHSHAFQRAMSGLTEVRENIQD
SFWSWRTLLYRFVSRIGPEDVHAIAAMAYAEMLEAGFTRVCEFHYVHNDEAGARYADPAEMAGQVVRAAGDTGLGLTLLP
VFYAHSGFGGQPPLDGQRRFLSDLEGFATLMDAAAKHGANQPDFVLGFAPHSLRAVTRAQLKALLAMDKAGPVHIHIAEQ
AQEVADCLAWSGARPVEWLLHNADVDARWCLVHATHTNDREIHGIAKSGAVAGLCPVTEANLGDGIFDGRGFVSYGGHYG
VGTDSNVSIGAADELRMLEYSQRFKTLSRNVLTGEGFASTGRSMFEHALAGGGRAAGISVGLAPGNPADMAAITDAVLPE
AAMGDDRLLDAWVFRAKSGAISDVWRRGEHVVQGGHHIHRPAIEARYKACLEALLA
>Mature_455_residues
AGKSSERLWFDHALLPSGWASGVAITIERGLIADVSVNVAPPSGAVRGRSVLPGLTNLHSHAFQRAMSGLTEVRENIQDS
FWSWRTLLYRFVSRIGPEDVHAIAAMAYAEMLEAGFTRVCEFHYVHNDEAGARYADPAEMAGQVVRAAGDTGLGLTLLPV
FYAHSGFGGQPPLDGQRRFLSDLEGFATLMDAAAKHGANQPDFVLGFAPHSLRAVTRAQLKALLAMDKAGPVHIHIAEQA
QEVADCLAWSGARPVEWLLHNADVDARWCLVHATHTNDREIHGIAKSGAVAGLCPVTEANLGDGIFDGRGFVSYGGHYGV
GTDSNVSIGAADELRMLEYSQRFKTLSRNVLTGEGFASTGRSMFEHALAGGGRAAGISVGLAPGNPADMAAITDAVLPEA
AMGDDRLLDAWVFRAKSGAISDVWRRGEHVVQGGHHIHRPAIEARYKACLEALLA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=415, Percent_Identity=29.6385542168675, Blast_Score=174, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48726; Mature: 48594

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKSSERLWFDHALLPSGWASGVAITIERGLIADVSVNVAPPSGAVRGRSVLPGLTNLH
CCCCCCCCEEEHHCCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCHHHHH
SHAFQRAMSGLTEVRENIQDSFWSWRTLLYRFVSRIGPEDVHAIAAMAYAEMLEAGFTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
CEFHYVHNDEAGARYADPAEMAGQVVRAAGDTGLGLTLLPVFYAHSGFGGQPPLDGQRRF
HHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
LSDLEGFATLMDAAAKHGANQPDFVLGFAPHSLRAVTRAQLKALLAMDKAGPVHIHIAEQ
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
AQEVADCLAWSGARPVEWLLHNADVDARWCLVHATHTNDREIHGIAKSGAVAGLCPVTEA
HHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCHHCCCCEEECCCCCC
NLGDGIFDGRGFVSYGGHYGVGTDSNVSIGAADELRMLEYSQRFKTLSRNVLTGEGFAST
CCCCCCCCCCCEEECCCEECCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
GRSMFEHALAGGGRAAGISVGLAPGNPADMAAITDAVLPEAAMGDDRLLDAWVFRAKSGA
HHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
ISDVWRRGEHVVQGGHHIHRPAIEARYKACLEALLA
HHHHHHCCHHHHCCCCHHCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AGKSSERLWFDHALLPSGWASGVAITIERGLIADVSVNVAPPSGAVRGRSVLPGLTNLH
CCCCCCCEEEHHCCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCHHHHH
SHAFQRAMSGLTEVRENIQDSFWSWRTLLYRFVSRIGPEDVHAIAAMAYAEMLEAGFTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
CEFHYVHNDEAGARYADPAEMAGQVVRAAGDTGLGLTLLPVFYAHSGFGGQPPLDGQRRF
HHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
LSDLEGFATLMDAAAKHGANQPDFVLGFAPHSLRAVTRAQLKALLAMDKAGPVHIHIAEQ
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
AQEVADCLAWSGARPVEWLLHNADVDARWCLVHATHTNDREIHGIAKSGAVAGLCPVTEA
HHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCHHCCCCEEECCCCCC
NLGDGIFDGRGFVSYGGHYGVGTDSNVSIGAADELRMLEYSQRFKTLSRNVLTGEGFAST
CCCCCCCCCCCEEECCCEECCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
GRSMFEHALAGGGRAAGISVGLAPGNPADMAAITDAVLPEAAMGDDRLLDAWVFRAKSGA
HHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
ISDVWRRGEHVVQGGHHIHRPAIEARYKACLEALLA
HHHHHHCCHHHHCCCCHHCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA