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The map label for this gene is hutC [H]

Identifier: 114799323

GI number: 114799323

Start: 2497774

End: 2498496

Strand: Reverse

Name: hutC [H]

Synonym: HNE_2393

Alternate gene names: 114799323

Gene position: 2498496-2497774 (Counterclockwise)

Preceding gene: 114798152

Following gene: 114798335

Centisome position: 67.44

GC content: 67.5

Gene sequence:

>723_bases
ATGCGCGACCCTTCCGAACCCCTTTCCGTCAGCGAACGCATCCGCTCCGACATCGAGCGCCAGATCCTTTCCGGGGGGCT
GAAGCCGGATGACCGCATCCCGCTGGAGCGGGAGCTGATGGAGATTTACGACTGCTCTCGCATGACGGTGAACAAGGCGG
TGAGCGATCTGGCGAGCCGGGGGCTGATCGTGCGCCGGAAACGGGCCGGCTCGTTCGTGGCGCACCCGCCCAGCGATTCC
ACCATCCTTGACGTTCCCGACATTCGCCTCGACCTGGAGCGTAAGGGGCATCGCTATGACTACACGCTGCTACGCCGGGC
CGTGCGCCGGGCCAAGGGAGAAGGCGAGCAAGCGCTGGCGGGCAAGGGCGGGCGGCTGATTGAGCTGCGCGGCGTGCACC
AGGCCGATGGGCAGCCGTTCGGTTTCGAGCGCCGGCTGGTAAACCTCGCGGCGGTGCCCGAGGTTGAAGCGGCCGACTTT
GCCGAAACCCCGCCAGGCACCTGGCTTTTGGGGCATGTGCCCTGGTCGCAGGCCGAGCACCGGATCTTTGCGGTGGCGGG
CGACCCCGCCATTGCAGCCCATCTCGATATTCCGGAAGGCGCGCCGTGCCTGCTGCTGGAGCGGCGGACATGGCTTAACG
GCGTGCCGGTGACGCATGTGTGGCAGACTTTCCCCGGCGACCGGCATTCCTTCATCGGCGAGCTGACCCGGCGGCAGGCC
TGA

Upstream 100 bases:

>100_bases
CGGTACAAAGCCTGCCTTGAGGCGCTTCTGGCGTGACAAAAGCCGGACAAATCTGGACAAACTTGGACAAATCGAGACAA
AGCCGGACAAAACAGGACAC

Downstream 100 bases:

>100_bases
GTAGTTTCCCGGATAGGGCGGGTTCTGACGCGAGGACAGGCTTGTATCCGGAAAATCGCGTGGCAGGTTCGTCTGATAAC
TGAATATCAGGGGAGTTTGC

Product: putative histidine utilization repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRDPSEPLSVSERIRSDIERQILSGGLKPDDRIPLERELMEIYDCSRMTVNKAVSDLASRGLIVRRKRAGSFVAHPPSDS
TILDVPDIRLDLERKGHRYDYTLLRRAVRRAKGEGEQALAGKGGRLIELRGVHQADGQPFGFERRLVNLAAVPEVEAADF
AETPPGTWLLGHVPWSQAEHRIFAVAGDPAIAAHLDIPEGAPCLLLERRTWLNGVPVTHVWQTFPGDRHSFIGELTRRQA

Sequences:

>Translated_240_residues
MRDPSEPLSVSERIRSDIERQILSGGLKPDDRIPLERELMEIYDCSRMTVNKAVSDLASRGLIVRRKRAGSFVAHPPSDS
TILDVPDIRLDLERKGHRYDYTLLRRAVRRAKGEGEQALAGKGGRLIELRGVHQADGQPFGFERRLVNLAAVPEVEAADF
AETPPGTWLLGHVPWSQAEHRIFAVAGDPAIAAHLDIPEGAPCLLLERRTWLNGVPVTHVWQTFPGDRHSFIGELTRRQA
>Mature_240_residues
MRDPSEPLSVSERIRSDIERQILSGGLKPDDRIPLERELMEIYDCSRMTVNKAVSDLASRGLIVRRKRAGSFVAHPPSDS
TILDVPDIRLDLERKGHRYDYTLLRRAVRRAKGEGEQALAGKGGRLIELRGVHQADGQPFGFERRLVNLAAVPEVEAADF
AETPPGTWLLGHVPWSQAEHRIFAVAGDPAIAAHLDIPEGAPCLLLERRTWLNGVPVTHVWQTFPGDRHSFIGELTRRQA

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26811; Mature: 26811

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPSEPLSVSERIRSDIERQILSGGLKPDDRIPLERELMEIYDCSRMTVNKAVSDLASR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
GLIVRRKRAGSFVAHPPSDSTILDVPDIRLDLERKGHRYDYTLLRRAVRRAKGEGEQALA
CEEEEECCCCCEEECCCCCCEEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHC
GKGGRLIELRGVHQADGQPFGFERRLVNLAAVPEVEAADFAETPPGTWLLGHVPWSQAEH
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
RIFAVAGDPAIAAHLDIPEGAPCLLLERRTWLNGVPVTHVWQTFPGDRHSFIGELTRRQA
EEEEEECCCEEEEEECCCCCCCEEEEECCHHCCCCCHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRDPSEPLSVSERIRSDIERQILSGGLKPDDRIPLERELMEIYDCSRMTVNKAVSDLASR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
GLIVRRKRAGSFVAHPPSDSTILDVPDIRLDLERKGHRYDYTLLRRAVRRAKGEGEQALA
CEEEEECCCCCEEECCCCCCEEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHC
GKGGRLIELRGVHQADGQPFGFERRLVNLAAVPEVEAADFAETPPGTWLLGHVPWSQAEH
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
RIFAVAGDPAIAAHLDIPEGAPCLLLERRTWLNGVPVTHVWQTFPGDRHSFIGELTRRQA
EEEEEECCCEEEEEECCCCCCCEEEEECCHHCCCCCHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]