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The map label for this gene is tadA [H]

Identifier: 114798136

GI number: 114798136

Start: 2940664

End: 2941104

Strand: Reverse

Name: tadA [H]

Synonym: HNE_2776

Alternate gene names: 114798136

Gene position: 2941104-2940664 (Counterclockwise)

Preceding gene: 114799259

Following gene: 114800280

Centisome position: 79.38

GC content: 70.07

Gene sequence:

>441_bases
ATGGCCCGCGCGATGGAACTGGCGCGTGAAGCGGCGAAGGCCGGCGAGGTGCCGGTGGGCGCCGTGGTGGTGGACCCGGA
GACCGGGGAGATCGTTGGCGAGGGGTATAACCGCCCCGTGGGCACACATGATCCGAGCGCCCATGCCGAGATCATTGCCA
TCCGCGCGGCGGCGCAGAAGCTTGGCAATTACCGGCTGACGGGGCTGGACCTGCATGTGACGCTGGAGCCGTGTGCGATG
TGCGCCGGGGCGATCAGCTTTGCGCGGATCGGGCGGCTTGTTTTTGCGGCGGCCGACATCAAGGGCGGGGCGGTGATGAG
CGGGCCGCGCTTCTTCGAGCAGCCGACCTGCCACTGGCGGCCCGAATGGCGCCAGGACGCGCTGCACGAAGCTGAGGCGG
CCGACCTGCTCCGGGACTTCTTCCGCACCCGCCGGGGCTGA

Upstream 100 bases:

>100_bases
TCGAAATTTAGACGCGGGGCTGTAATCCGTTGACGGATTTACCTTTACTTTCAGGGGCTGAGACGCAATCTGCTGTTCGA
TGAATATGCAGATTGAAGCA

Downstream 100 bases:

>100_bases
CAAAGCCGTAATCAGGCTGCATGACTGGTCTTCACATCTGAAGGGGACGATTTGCCCATGGAGCATGCCGCGCACGGGCC
AAGCCCGACCCTGATCAAGG

Product: cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MARAMELAREAAKAGEVPVGAVVVDPETGEIVGEGYNRPVGTHDPSAHAEIIAIRAAAQKLGNYRLTGLDLHVTLEPCAM
CAGAISFARIGRLVFAAADIKGGAVMSGPRFFEQPTCHWRPEWRQDALHEAEAADLLRDFFRTRRG

Sequences:

>Translated_146_residues
MARAMELAREAAKAGEVPVGAVVVDPETGEIVGEGYNRPVGTHDPSAHAEIIAIRAAAQKLGNYRLTGLDLHVTLEPCAM
CAGAISFARIGRLVFAAADIKGGAVMSGPRFFEQPTCHWRPEWRQDALHEAEAADLLRDFFRTRRG
>Mature_145_residues
ARAMELAREAAKAGEVPVGAVVVDPETGEIVGEGYNRPVGTHDPSAHAEIIAIRAAAQKLGNYRLTGLDLHVTLEPCAMC
AGAISFARIGRLVFAAADIKGGAVMSGPRFFEQPTCHWRPEWRQDALHEAEAADLLRDFFRTRRG

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=145, Percent_Identity=49.6551724137931, Blast_Score=129, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17554608, Length=115, Percent_Identity=34.7826086956522, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=98, Percent_Identity=38.7755102040816, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17541138, Length=110, Percent_Identity=38.1818181818182, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15794; Mature: 15663

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAMELAREAAKAGEVPVGAVVVDPETGEIVGEGYNRPVGTHDPSAHAEIIAIRAAAQK
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
LGNYRLTGLDLHVTLEPCAMCAGAISFARIGRLVFAAADIKGGAVMSGPRFFEQPTCHWR
HCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
PEWRQDALHEAEAADLLRDFFRTRRG
CCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARAMELAREAAKAGEVPVGAVVVDPETGEIVGEGYNRPVGTHDPSAHAEIIAIRAAAQK
CHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
LGNYRLTGLDLHVTLEPCAMCAGAISFARIGRLVFAAADIKGGAVMSGPRFFEQPTCHWR
HCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
PEWRQDALHEAEAADLLRDFFRTRRG
CCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]