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The map label for this gene is crt [H]

Identifier: 114799259

GI number: 114799259

Start: 2941194

End: 2941862

Strand: Reverse

Name: crt [H]

Synonym: HNE_2777

Alternate gene names: 114799259

Gene position: 2941862-2941194 (Counterclockwise)

Preceding gene: 114797727

Following gene: 114798136

Centisome position: 79.4

GC content: 64.28

Gene sequence:

>669_bases
GTGACCGCCACCGTGAAAATCGAGAATGAGATTGCTGTCGTCACTATGGATGATGGCAAGGCCAACGCCATCAGCCTGAC
GATGCTGGAAGCGGTGAACGCGGCGCTGGACGAGGCGGAGACGGCGGCGAAGGTGATCGTGCTGGCCGGGCGGCCGGAGC
GGTTTTCGGCAGGGTTTGACCTGAAGTTTCTCGCTTCATCCGAGCCCGATCAGGTGCGCAAGCTGGTGATGGGCGGGGGC
AAGCTGGCGTTCCGGCTGTTTACCTCTGACAAGCCGGTCGTCATTGCGTGTACGGGACATGCCATTGCCATGGGGGCGTT
CATCCTGCTGGCCGGGGATACGCGGATTGCGGCGCGGGGCGCCTACAAGATCGGCGCGAATGAGACGGTGAACGGCATGA
CGCTGCCAGGCTTCGGGGTGGAGCTGCCGCGGGCGAGGCTCAACCCGATGTATCTGACGCAGGCGCTGGCGCAGGCGAAG
CTCTACACGCCCGATGAAGCGCTGCCCGTGGGCTGGGTGGACCAGGTGGTGGAGCCGGGCGAAGTGCTGGGCGCGGCGAT
GGCGGAGGCCGAGCGGCTGCTCCCGATTGCCAACTACGCTTATGGCCGGAACAAGAAGTATGCCCGCCAGCCGGCAATTG
ATCTGATTGCGCCGACGCTCGAAATTTAG

Upstream 100 bases:

>100_bases
CCGCGCGAATGACAACCGTTCGGGATGACGCCGCGCGAGGGCTTGATTTCTACTCACGCTAGAGTTTCTCTGAGGCCTGC
AACTGAGGAGCTTTCCCGCC

Downstream 100 bases:

>100_bases
ACGCGGGGCTGTAATCCGTTGACGGATTTACCTTTACTTTCAGGGGCTGAGACGCAATCTGCTGTTCGATGAATATGCAG
ATTGAAGCAATGGCCCGCGC

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTATVKIENEIAVVTMDDGKANAISLTMLEAVNAALDEAETAAKVIVLAGRPERFSAGFDLKFLASSEPDQVRKLVMGGG
KLAFRLFTSDKPVVIACTGHAIAMGAFILLAGDTRIAARGAYKIGANETVNGMTLPGFGVELPRARLNPMYLTQALAQAK
LYTPDEALPVGWVDQVVEPGEVLGAAMAEAERLLPIANYAYGRNKKYARQPAIDLIAPTLEI

Sequences:

>Translated_222_residues
MTATVKIENEIAVVTMDDGKANAISLTMLEAVNAALDEAETAAKVIVLAGRPERFSAGFDLKFLASSEPDQVRKLVMGGG
KLAFRLFTSDKPVVIACTGHAIAMGAFILLAGDTRIAARGAYKIGANETVNGMTLPGFGVELPRARLNPMYLTQALAQAK
LYTPDEALPVGWVDQVVEPGEVLGAAMAEAERLLPIANYAYGRNKKYARQPAIDLIAPTLEI
>Mature_221_residues
TATVKIENEIAVVTMDDGKANAISLTMLEAVNAALDEAETAAKVIVLAGRPERFSAGFDLKFLASSEPDQVRKLVMGGGK
LAFRLFTSDKPVVIACTGHAIAMGAFILLAGDTRIAARGAYKIGANETVNGMTLPGFGVELPRARLNPMYLTQALAQAKL
YTPDEALPVGWVDQVVEPGEVLGAAMAEAERLLPIANYAYGRNKKYARQPAIDLIAPTLEI

Specific function: Catalyzes The Reversible Dehydration Of L-Carnitinyl-CoA To Crotobetainyl-CoA. [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI62530384, Length=204, Percent_Identity=29.9019607843137, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583165, Length=182, Percent_Identity=26.3736263736264, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 23604; Mature: 23472

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATVKIENEIAVVTMDDGKANAISLTMLEAVNAALDEAETAAKVIVLAGRPERFSAGFD
CCEEEEECCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
LKFLASSEPDQVRKLVMGGGKLAFRLFTSDKPVVIACTGHAIAMGAFILLAGDTRIAARG
EEEECCCCHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHEEEEEEEECCCEEEECC
AYKIGANETVNGMTLPGFGVELPRARLNPMYLTQALAQAKLYTPDEALPVGWVDQVVEPG
EEEECCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCH
EVLGAAMAEAERLLPIANYAYGRNKKYARQPAIDLIAPTLEI
HHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure 
TATVKIENEIAVVTMDDGKANAISLTMLEAVNAALDEAETAAKVIVLAGRPERFSAGFD
CEEEEECCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
LKFLASSEPDQVRKLVMGGGKLAFRLFTSDKPVVIACTGHAIAMGAFILLAGDTRIAARG
EEEECCCCHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHEEEEEEEECCCEEEECC
AYKIGANETVNGMTLPGFGVELPRARLNPMYLTQALAQAKLYTPDEALPVGWVDQVVEPG
EEEECCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCH
EVLGAAMAEAERLLPIANYAYGRNKKYARQPAIDLIAPTLEI
HHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]