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The map label for this gene is add [H]

Identifier: 114797828

GI number: 114797828

Start: 2006154

End: 2007167

Strand: Direct

Name: add [H]

Synonym: HNE_1938

Alternate gene names: 114797828

Gene position: 2006154-2007167 (Clockwise)

Preceding gene: 114800222

Following gene: 114798369

Centisome position: 54.15

GC content: 58.97

Gene sequence:

>1014_bases
ATGAAAGCGCCCGGCAGCCAGACGGACCTGATCCGCCGCCTGCCCAAGGCCGAACTTCACCTGCACATCGAAGGCAGCTT
CGAACCAGAACAGATGATGGCGCTGGCAGAGCGCAACAAGATCGTCCTGCCTTTCAAGACGCTGGAAGACGCAAAAGCGG
CTTACGCTTTCTCCAACCTCCAGGAATTTCTCGACCTCTACTATCAGGGCATGCAGGTGCTGCGCACCGAGGAAGACTTC
TTCGACCTGACCTGGGCGTATCTCCAGCGGGCCAAGGCCGACAATGTCCGCCATGTGGAGATGTTCTACGATCCCCAGGC
CCATACCGAGCGGGGCGTGCCCTTCGGCGTGGTCACGGACGGCATCCTCGCCGCCATCAAGAAGGGTGAGCAGGAACTCG
GCATCACTTCCTACCTCATCATGAGTTTCCTGCGCCATCTTTCGGAAGAGGACGGCTTTGACCTGCTGGTCGAGTCCGAG
CCTTGGCATGACAAGTTTATCGGCGTCGGCCTCGACTCCTCAGAAATGGGCCACCCGCCCCTGAAGTTCGAGCGGCTCTA
TCAGCGCTGCCGCGAAATCGGCTTCAAGCTGAGCATGCATGCCGGCGAAGAAGGCCCGCCGTCCTACGTTCGCGAAGCCC
TGCTCGACATCGGCGTCGACCGGATCGACCACGGCAACCGCTGTATGGAAGACCCCGAACTCGTCAGTATCCTCCGCGAA
ATGCAGGTGCCGCTGACCAACTGCCCGCTGTCGAACCTGTCGCTCTGCGTCATTGATGATCTGAAAAAAAGCCCCGTCAA
AGCGCAGCTCGAACAAGGTCTCTTGGTCACAGTCAATTCTGACGACCCGGCCTATTTCGGCGGCTATATCGGCCGCAATT
ACGAGCAAACCGCAGCGGCGCTTGATCTGTCAGACAGTCAGCTTATCCAGCTCGCCCGTAATAGCTTCACAGCCAGTTTT
CTTCTCGATGCAGACAAACAGCGTCACCTGGCTGAAGTAGACGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCGCGTCCTCGGCATGATGCCCCACCCGGAACGCGCTATCGGCAACCATGAAGGCGGCAGCGACGGCGCGGCACTCTTC
AAAAGCCTGATGGCGGCGGC

Downstream 100 bases:

>100_bases
AATACAGACGGCCGCTTTCTTACTGCGTCAGCTATTGGTTTCGGCCTCTTCAGCCGCGTCTTCTGAATCGGCCTCAGCCT
CTTCATCCGGGGCTTCAGCC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKAPGSQTDLIRRLPKAELHLHIEGSFEPEQMMALAERNKIVLPFKTLEDAKAAYAFSNLQEFLDLYYQGMQVLRTEEDF
FDLTWAYLQRAKADNVRHVEMFYDPQAHTERGVPFGVVTDGILAAIKKGEQELGITSYLIMSFLRHLSEEDGFDLLVESE
PWHDKFIGVGLDSSEMGHPPLKFERLYQRCREIGFKLSMHAGEEGPPSYVREALLDIGVDRIDHGNRCMEDPELVSILRE
MQVPLTNCPLSNLSLCVIDDLKKSPVKAQLEQGLLVTVNSDDPAYFGGYIGRNYEQTAAALDLSDSQLIQLARNSFTASF
LLDADKQRHLAEVDAAA

Sequences:

>Translated_337_residues
MKAPGSQTDLIRRLPKAELHLHIEGSFEPEQMMALAERNKIVLPFKTLEDAKAAYAFSNLQEFLDLYYQGMQVLRTEEDF
FDLTWAYLQRAKADNVRHVEMFYDPQAHTERGVPFGVVTDGILAAIKKGEQELGITSYLIMSFLRHLSEEDGFDLLVESE
PWHDKFIGVGLDSSEMGHPPLKFERLYQRCREIGFKLSMHAGEEGPPSYVREALLDIGVDRIDHGNRCMEDPELVSILRE
MQVPLTNCPLSNLSLCVIDDLKKSPVKAQLEQGLLVTVNSDDPAYFGGYIGRNYEQTAAALDLSDSQLIQLARNSFTASF
LLDADKQRHLAEVDAAA
>Mature_337_residues
MKAPGSQTDLIRRLPKAELHLHIEGSFEPEQMMALAERNKIVLPFKTLEDAKAAYAFSNLQEFLDLYYQGMQVLRTEEDF
FDLTWAYLQRAKADNVRHVEMFYDPQAHTERGVPFGVVTDGILAAIKKGEQELGITSYLIMSFLRHLSEEDGFDLLVESE
PWHDKFIGVGLDSSEMGHPPLKFERLYQRCREIGFKLSMHAGEEGPPSYVREALLDIGVDRIDHGNRCMEDPELVSILRE
MQVPLTNCPLSNLSLCVIDDLKKSPVKAQLEQGLLVTVNSDDPAYFGGYIGRNYEQTAAALDLSDSQLIQLARNSFTASF
LLDADKQRHLAEVDAAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=343, Percent_Identity=23.6151603498542, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1787910, Length=331, Percent_Identity=27.190332326284, Blast_Score=134, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17538512, Length=355, Percent_Identity=24.7887323943662, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565969, Length=340, Percent_Identity=24.7058823529412, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324188, Length=336, Percent_Identity=41.3690476190476, Blast_Score=243, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24645260, Length=325, Percent_Identity=26.7692307692308, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38013; Mature: 38013

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPGSQTDLIRRLPKAELHLHIEGSFEPEQMMALAERNKIVLPFKTLEDAKAAYAFSNL
CCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
QEFLDLYYQGMQVLRTEEDFFDLTWAYLQRAKADNVRHVEMFYDPQAHTERGVPFGVVTD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHH
GILAAIKKGEQELGITSYLIMSFLRHLSEEDGFDLLVESEPWHDKFIGVGLDSSEMGHPP
HHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCC
LKFERLYQRCREIGFKLSMHAGEEGPPSYVREALLDIGVDRIDHGNRCMEDPELVSILRE
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHH
MQVPLTNCPLSNLSLCVIDDLKKSPVKAQLEQGLLVTVNSDDPAYFGGYIGRNYEQTAAA
HCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCEEEEECCCCCCCCCHHHCCCHHHHHHH
LDLSDSQLIQLARNSFTASFLLDADKQRHLAEVDAAA
HCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHHCCCC
>Mature Secondary Structure
MKAPGSQTDLIRRLPKAELHLHIEGSFEPEQMMALAERNKIVLPFKTLEDAKAAYAFSNL
CCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
QEFLDLYYQGMQVLRTEEDFFDLTWAYLQRAKADNVRHVEMFYDPQAHTERGVPFGVVTD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHH
GILAAIKKGEQELGITSYLIMSFLRHLSEEDGFDLLVESEPWHDKFIGVGLDSSEMGHPP
HHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCC
LKFERLYQRCREIGFKLSMHAGEEGPPSYVREALLDIGVDRIDHGNRCMEDPELVSILRE
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHH
MQVPLTNCPLSNLSLCVIDDLKKSPVKAQLEQGLLVTVNSDDPAYFGGYIGRNYEQTAAA
HCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCEEEEECCCCCCCCCHHHCCCHHHHHHH
LDLSDSQLIQLARNSFTASFLLDADKQRHLAEVDAAA
HCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA