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The map label for this gene is purQ [H]

Identifier: 114800222

GI number: 114800222

Start: 2005489

End: 2006157

Strand: Direct

Name: purQ [H]

Synonym: HNE_1937

Alternate gene names: 114800222

Gene position: 2005489-2006157 (Clockwise)

Preceding gene: 114799389

Following gene: 114797828

Centisome position: 54.13

GC content: 63.08

Gene sequence:

>669_bases
ATGAAATCTGCTGTTATCGTCTTTCCAGGCTCCAACTGTGATCGTGACGCGCATGACGCGTTGAAGAAGCTGACCGGCAA
TGCGCCCGCGATGGTCTGGCACAAGGATGGGGAAATCCCTGCCGGAACAGACCTGGTGATGGTGCCCGGCGGCTTTTCCT
ACGGCGATTACCTGCGCTGCGGCGCCATGGCGGGCAATTCGCCCATCATCGCTCAGCTGAAAGCCCATGCCGAACGCGGC
GGCTATATCCTCGGCGTCTGCAACGGCTTCCAGATCCTCACCGAGACCGGCCTGCTGCCCGGCGCGCTGGTGCGTAACGC
CTCGCTCCATTTCGTCTGCCGCCCGCAGAAACTGAAGGTCGAGAGCAGCAACACCGCCTTCACCAGCGCCTATACCGGCG
GCAGCGAAGTGGTCATCCCGATCGCCCATGCCGAAGGCAACTTCTTTGCCGACGACACCATGCTTGATCGTCTCGAAGGC
GAAGGCCGCGTGGCCTTCCGCTATGCCAGCGGCGAAAACCCCAACGGCGCTGCTCGCGACATTGCCGGCATCCTCTCGGA
AAACGGCCGCGTCCTCGGCATGATGCCCCACCCGGAACGCGCTATCGGCAACCATGAAGGCGGCAGCGACGGCGCGGCAC
TCTTCAAAAGCCTGATGGCGGCGGCATGA

Upstream 100 bases:

>100_bases
TATACTTTACGAACAACGGGTTATGTGGCTGAAAAGCCTCACTGTGCTGCGCCCGTCATTCCCGTTTCCAAACCGCCCGA
CTCTTTGCTAAAGAGCGCCC

Downstream 100 bases:

>100_bases
AAGCGCCCGGCAGCCAGACGGACCTGATCCGCCGCCTGCCCAAGGCCGAACTTCACCTGCACATCGAAGGCAGCTTCGAA
CCAGAACAGATGATGGCGCT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKSAVIVFPGSNCDRDAHDALKKLTGNAPAMVWHKDGEIPAGTDLVMVPGGFSYGDYLRCGAMAGNSPIIAQLKAHAERG
GYILGVCNGFQILTETGLLPGALVRNASLHFVCRPQKLKVESSNTAFTSAYTGGSEVVIPIAHAEGNFFADDTMLDRLEG
EGRVAFRYASGENPNGAARDIAGILSENGRVLGMMPHPERAIGNHEGGSDGAALFKSLMAAA

Sequences:

>Translated_222_residues
MKSAVIVFPGSNCDRDAHDALKKLTGNAPAMVWHKDGEIPAGTDLVMVPGGFSYGDYLRCGAMAGNSPIIAQLKAHAERG
GYILGVCNGFQILTETGLLPGALVRNASLHFVCRPQKLKVESSNTAFTSAYTGGSEVVIPIAHAEGNFFADDTMLDRLEG
EGRVAFRYASGENPNGAARDIAGILSENGRVLGMMPHPERAIGNHEGGSDGAALFKSLMAAA
>Mature_222_residues
MKSAVIVFPGSNCDRDAHDALKKLTGNAPAMVWHKDGEIPAGTDLVMVPGGFSYGDYLRCGAMAGNSPIIAQLKAHAERG
GYILGVCNGFQILTETGLLPGALVRNASLHFVCRPQKLKVESSNTAFTSAYTGGSEVVIPIAHAEGNFFADDTMLDRLEG
EGRVAFRYASGENPNGAARDIAGILSENGRVLGMMPHPERAIGNHEGGSDGAALFKSLMAAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=176, Percent_Identity=34.6590909090909, Blast_Score=78, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=182, Percent_Identity=35.7142857142857, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24582111, Length=186, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24582109, Length=186, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17137292, Length=186, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23261; Mature: 23261

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVIVFPGSNCDRDAHDALKKLTGNAPAMVWHKDGEIPAGTDLVMVPGGFSYGDYLRC
CCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEE
GAMAGNSPIIAQLKAHAERGGYILGVCNGFQILTETGLLPGALVRNASLHFVCRPQKLKV
CCCCCCCCEEEEEEHHHCCCCEEEEEECCEEEEECCCCCCHHHHCCCCEEEEECCCEEEE
ESSNTAFTSAYTGGSEVVIPIAHAEGNFFADDTMLDRLEGEGRVAFRYASGENPNGAARD
ECCCCEEEEEECCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCHHHH
IAGILSENGRVLGMMPHPERAIGNHEGGSDGAALFKSLMAAA
HHHHHCCCCCEEEECCCCHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKSAVIVFPGSNCDRDAHDALKKLTGNAPAMVWHKDGEIPAGTDLVMVPGGFSYGDYLRC
CCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEE
GAMAGNSPIIAQLKAHAERGGYILGVCNGFQILTETGLLPGALVRNASLHFVCRPQKLKV
CCCCCCCCEEEEEEHHHCCCCEEEEEECCEEEEECCCCCCHHHHCCCCEEEEECCCEEEE
ESSNTAFTSAYTGGSEVVIPIAHAEGNFFADDTMLDRLEGEGRVAFRYASGENPNGAARD
ECCCCEEEEEECCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCHHHH
IAGILSENGRVLGMMPHPERAIGNHEGGSDGAALFKSLMAAA
HHHHHCCCCCEEEECCCCHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA