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The map label for this gene is regA [H]

Identifier: 114797184

GI number: 114797184

Start: 3544666

End: 3545238

Strand: Direct

Name: regA [H]

Synonym: HNE_3399

Alternate gene names: 114797184

Gene position: 3544666-3545238 (Clockwise)

Preceding gene: 114799590

Following gene: 114797487

Centisome position: 95.67

GC content: 63.53

Gene sequence:

>573_bases
ATGGAACGCCCAGCTGTCGTGAACCTGCATCCGAGCCTTGAAGGCGTCGAAGATAAATCCTGCCTCGTCATGGATGACGA
CGGGCCGTTCGTGCAGCGCCTTGCGCGCGCGCTGGCCCAGCGTGGCTTCATCGTATCGGCCGTTTCCAATGTGTCGGAAG
GCAAGGACATCGCCCGCCTGAACCCACCCGCCTTTGCAGTGCTGGACCTGCGTCTGGAAGATGGCAGCGGTCTGGATGTG
GTCGAAGTGCTGCAAAAGCACCGTCCGGAAGCGCGCGCCGTGATCCTGACCGGCTATGGCGCCATTGCCACGGCGGTTGC
CGCCGTAAAGGCGGGCGCGGTCGATTATCTCTCCAAGCCGGCGGACGTTGAAGACATCATCCGCTCGCTGACCGCCTCGC
AGGACGAACGCCCTGCCCCTCCCGAGAACCCCATGTCGGCAGACCGGGTGCGCTGGGAACACATCCAGCGCGTTTATGAG
CTGTGCAATCACAATGTCTCGGAAACGGCGCGCCGCCTCAACATGCATCGCCGCACGCTGCAACGCATCCTGGCCAAGCG
CGCGCCGAAATAG

Upstream 100 bases:

>100_bases
TTTGGCCGCTGCAGGCGCTGCTTCCACGAAGCTTGGACTAGTTGACAATTACGCCATATATCCTCTTACCGGCGGCAAGA
CCGCCTGAAGGAGAGTGCGT

Downstream 100 bases:

>100_bases
GCGTCAGGCGTCTTCTTCCGGCTCCGGACTATTCCGCCCGAAGTTCACCGCGCTGGAATCCTGACCGGCATCGATGATCG
CCTTGCGGATGGTGCGGGCG

Product: DNA-binding response regulator RegA

Products: NA

Alternate protein names: Response regulator prrA [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MERPAVVNLHPSLEGVEDKSCLVMDDDGPFVQRLARALAQRGFIVSAVSNVSEGKDIARLNPPAFAVLDLRLEDGSGLDV
VEVLQKHRPEARAVILTGYGAIATAVAAVKAGAVDYLSKPADVEDIIRSLTASQDERPAPPENPMSADRVRWEHIQRVYE
LCNHNVSETARRLNMHRRTLQRILAKRAPK

Sequences:

>Translated_190_residues
MERPAVVNLHPSLEGVEDKSCLVMDDDGPFVQRLARALAQRGFIVSAVSNVSEGKDIARLNPPAFAVLDLRLEDGSGLDV
VEVLQKHRPEARAVILTGYGAIATAVAAVKAGAVDYLSKPADVEDIIRSLTASQDERPAPPENPMSADRVRWEHIQRVYE
LCNHNVSETARRLNMHRRTLQRILAKRAPK
>Mature_190_residues
MERPAVVNLHPSLEGVEDKSCLVMDDDGPFVQRLARALAQRGFIVSAVSNVSEGKDIARLNPPAFAVLDLRLEDGSGLDV
VEVLQKHRPEARAVILTGYGAIATAVAAVKAGAVDYLSKPADVEDIIRSLTASQDERPAPPENPMSADRVRWEHIQRVYE
LCNHNVSETARRLNMHRRTLQRILAKRAPK

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20932; Mature: 20932

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPAVVNLHPSLEGVEDKSCLVMDDDGPFVQRLARALAQRGFIVSAVSNVSEGKDIARL
CCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHC
NPPAFAVLDLRLEDGSGLDVVEVLQKHRPEARAVILTGYGAIATAVAAVKAGAVDYLSKP
CCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
ADVEDIIRSLTASQDERPAPPENPMSADRVRWEHIQRVYELCNHNVSETARRLNMHRRTL
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QRILAKRAPK
HHHHHHCCCC
>Mature Secondary Structure
MERPAVVNLHPSLEGVEDKSCLVMDDDGPFVQRLARALAQRGFIVSAVSNVSEGKDIARL
CCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHC
NPPAFAVLDLRLEDGSGLDVVEVLQKHRPEARAVILTGYGAIATAVAAVKAGAVDYLSKP
CCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
ADVEDIIRSLTASQDERPAPPENPMSADRVRWEHIQRVYELCNHNVSETARRLNMHRRTL
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QRILAKRAPK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181698; 8282708 [H]