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The map label for this gene is regB [H]

Identifier: 114799590

GI number: 114799590

Start: 3543239

End: 3544606

Strand: Direct

Name: regB [H]

Synonym: HNE_3398

Alternate gene names: 114799590

Gene position: 3543239-3544606 (Clockwise)

Preceding gene: 114799537

Following gene: 114797184

Centisome position: 95.63

GC content: 65.72

Gene sequence:

>1368_bases
ATGGATGAGTTCACCCGAGATTCGAGAACAGGCTTTGAAGACGCGATCTTCATGCTGGCCCCTGAGGGGCTGGGCTCGGC
CCAGTCCGCCCTCGGGCGCACCCGGCTGCGCACGTTCATTACGCTGCGCTGGCTTGCTGTAGCCGGGCAGACAGGGGCGG
TTCTGCTCGTCGCCTTTATCCTGGGCTTCGACCTTCCCCTGGCCCTGTGCCTGGCCATCATTGCCGCGTCCGCCTGGCTG
AACGTGTTCCTGTCCTTCGCCTTCCAGTCCCAGCGCCTGACCAGCGGCTGGGAAGCGGTGCTGCAGCTTGGCTTTGATAC
AGTGCAACTCGCAGCGCTGATCGCCGTCACGGGCGGGCTCTCCAATCCGTTCCTGTTGCTGATGCTCGCACCGGTCACTG
TGGCCGCGCTCAGCCTGCGGCGGATGCGCGCCAGCGCCATTGCGCTCCTCGCGCTGGGTCTTGCCGCGCTGATGCCGCTC
GTCAGCCTGCCCCTGCCCTGGGATGAAAGCGGCGGCACGCATCTGCCGATCCTCTTCCAATGGGGCCAGTTTGCCGCGCT
AGCTGTGGGCGTCGTGTTCTTCACCCTGTCCGCCGCAAGGGTCAGCCAGGATGAAGCCCGCCTTGTACGCGCCCTCGACG
CAGCCAGCGTTGTGATGGCGCGCGAACAGAAACTGTCGGCACTGGGCGCGATGTCGGCCATGACCGCGCATGAGCTGGGC
ACGCCGCTGGCCACCATCCATCTGGTTGCCAATGAGCTTGTTCAGCAGACCAGCCCCGATGATCCGCACGCCGAAGATTT
CCGGCTGATCGCCGAGCAGGCCGACCGGTGCCGCTCAATTCTCTCCGCCATCCGTGAAGCGCGCGACGCCACCGATATTG
TTCACGCCCGCATGCCGCTGGACACGCTGGTTGAGGAAGCCGCCGCCCCGATGAAGGGGTTGGGCGTGGCCCTGATAGTC
CGCGCGTTGCCCGGCGAAGGGGGCACAGACAAGCCGCCCATTCTCGCCCGCAGCCCGGAAATTCTGCATGCGCTGGGCGC
GTTCATCGAGAATGCGGTGAGCTTTGCCGCCACGCGCGTGGACGCGACCGCCAGCTGGACAGCCGATCAGGTGGTGATCA
CCATCACCGATGATGGCCCCGGATTTTCGCCCGAAGTGCTGCCCAAACTCGGCGAGCCGTACATTTCCGAGCGCTCCGAA
GCCCGCCTTGGCGGGGGCGACATGGGCCTTGGATTTTTCATCGCAAAGACGCTGATCGAGCGCACAGGCGGGCGAATCGC
GTCCCGAAACAGGACACCGCCGGCGACCGGCGCCATCGTCCAGGCTGTTTGGCCGCTGCAGGCGCTGCTTCCACGAAGCT
TGGACTAG

Upstream 100 bases:

>100_bases
GAAAAGCGCCGGAACGGCAAAGGCGGATGACATACGCATGCCCTGATAGGCCCCAATTCCGCCGCTTGGCGCAAGAGACA
GGCTGCCGCATAAGGCTGGC

Downstream 100 bases:

>100_bases
TTGACAATTACGCCATATATCCTCTTACCGGCGGCAAGACCGCCTGAAGGAGAGTGCGTATGGAACGCCCAGCTGTCGTG
AACCTGCATCCGAGCCTTGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MDEFTRDSRTGFEDAIFMLAPEGLGSAQSALGRTRLRTFITLRWLAVAGQTGAVLLVAFILGFDLPLALCLAIIAASAWL
NVFLSFAFQSQRLTSGWEAVLQLGFDTVQLAALIAVTGGLSNPFLLLMLAPVTVAALSLRRMRASAIALLALGLAALMPL
VSLPLPWDESGGTHLPILFQWGQFAALAVGVVFFTLSAARVSQDEARLVRALDAASVVMAREQKLSALGAMSAMTAHELG
TPLATIHLVANELVQQTSPDDPHAEDFRLIAEQADRCRSILSAIREARDATDIVHARMPLDTLVEEAAAPMKGLGVALIV
RALPGEGGTDKPPILARSPEILHALGAFIENAVSFAATRVDATASWTADQVVITITDDGPGFSPEVLPKLGEPYISERSE
ARLGGGDMGLGFFIAKTLIERTGGRIASRNRTPPATGAIVQAVWPLQALLPRSLD

Sequences:

>Translated_455_residues
MDEFTRDSRTGFEDAIFMLAPEGLGSAQSALGRTRLRTFITLRWLAVAGQTGAVLLVAFILGFDLPLALCLAIIAASAWL
NVFLSFAFQSQRLTSGWEAVLQLGFDTVQLAALIAVTGGLSNPFLLLMLAPVTVAALSLRRMRASAIALLALGLAALMPL
VSLPLPWDESGGTHLPILFQWGQFAALAVGVVFFTLSAARVSQDEARLVRALDAASVVMAREQKLSALGAMSAMTAHELG
TPLATIHLVANELVQQTSPDDPHAEDFRLIAEQADRCRSILSAIREARDATDIVHARMPLDTLVEEAAAPMKGLGVALIV
RALPGEGGTDKPPILARSPEILHALGAFIENAVSFAATRVDATASWTADQVVITITDDGPGFSPEVLPKLGEPYISERSE
ARLGGGDMGLGFFIAKTLIERTGGRIASRNRTPPATGAIVQAVWPLQALLPRSLD
>Mature_455_residues
MDEFTRDSRTGFEDAIFMLAPEGLGSAQSALGRTRLRTFITLRWLAVAGQTGAVLLVAFILGFDLPLALCLAIIAASAWL
NVFLSFAFQSQRLTSGWEAVLQLGFDTVQLAALIAVTGGLSNPFLLLMLAPVTVAALSLRRMRASAIALLALGLAALMPL
VSLPLPWDESGGTHLPILFQWGQFAALAVGVVFFTLSAARVSQDEARLVRALDAASVVMAREQKLSALGAMSAMTAHELG
TPLATIHLVANELVQQTSPDDPHAEDFRLIAEQADRCRSILSAIREARDATDIVHARMPLDTLVEEAAAPMKGLGVALIV
RALPGEGGTDKPPILARSPEILHALGAFIENAVSFAATRVDATASWTADQVVITITDDGPGFSPEVLPKLGEPYISERSE
ARLGGGDMGLGFFIAKTLIERTGGRIASRNRTPPATGAIVQAVWPLQALLPRSLD

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=24.3243243243243, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48267; Mature: 48267

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFTRDSRTGFEDAIFMLAPEGLGSAQSALGRTRLRTFITLRWLAVAGQTGAVLLVAFI
CCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LGFDLPLALCLAIIAASAWLNVFLSFAFQSQRLTSGWEAVLQLGFDTVQLAALIAVTGGL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
SNPFLLLMLAPVTVAALSLRRMRASAIALLALGLAALMPLVSLPLPWDESGGTHLPILFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
WGQFAALAVGVVFFTLSAARVSQDEARLVRALDAASVVMAREQKLSALGAMSAMTAHELG
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPLATIHLVANELVQQTSPDDPHAEDFRLIAEQADRCRSILSAIREARDATDIVHARMPL
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DTLVEEAAAPMKGLGVALIVRALPGEGGTDKPPILARSPEILHALGAFIENAVSFAATRV
HHHHHHHCCCHHHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
DATASWTADQVVITITDDGPGFSPEVLPKLGEPYISERSEARLGGGDMGLGFFIAKTLIE
CCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHH
RTGGRIASRNRTPPATGAIVQAVWPLQALLPRSLD
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDEFTRDSRTGFEDAIFMLAPEGLGSAQSALGRTRLRTFITLRWLAVAGQTGAVLLVAFI
CCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LGFDLPLALCLAIIAASAWLNVFLSFAFQSQRLTSGWEAVLQLGFDTVQLAALIAVTGGL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
SNPFLLLMLAPVTVAALSLRRMRASAIALLALGLAALMPLVSLPLPWDESGGTHLPILFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
WGQFAALAVGVVFFTLSAARVSQDEARLVRALDAASVVMAREQKLSALGAMSAMTAHELG
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPLATIHLVANELVQQTSPDDPHAEDFRLIAEQADRCRSILSAIREARDATDIVHARMPL
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DTLVEEAAAPMKGLGVALIVRALPGEGGTDKPPILARSPEILHALGAFIENAVSFAATRV
HHHHHHHCCCHHHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
DATASWTADQVVITITDDGPGFSPEVLPKLGEPYISERSEARLGGGDMGLGFFIAKTLIE
CCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHH
RTGGRIASRNRTPPATGAIVQAVWPLQALLPRSLD
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]