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The map label for this gene is fecR [H]

Identifier: 114332056

GI number: 114332056

Start: 2214409

End: 2215371

Strand: Direct

Name: fecR [H]

Synonym: Neut_2091

Alternate gene names: 114332056

Gene position: 2214409-2215371 (Clockwise)

Preceding gene: 114332055

Following gene: 114332057

Centisome position: 83.22

GC content: 51.92

Gene sequence:

>963_bases
ATGTCCGCTTCCGGCCCTCCTGACGAACAGCTGCTCAAACAGGCACTGAAGTGGTTTTTTCTATTACAGTCTGAACACTG
TACGGATGAAGACAAGCGGAAATTCAACCGCTGGTTCTGTAAAAATGAAGCTCATCAGGCAGCCTATACGCATGCTGAGC
GCTTATGGTCTGAAACAGACAAACTGAAAGAAACACCCGATATTCCCGGTTTGCATGAAGCCAGACGACGCCGGCCCAAA
CACCAGCCGGCCGGCATATTCGGCTGGGCACTGTTCTTCCTGATTTCATCTGCTTTGATGAGTATCAGCTGGCTGGAATA
CAACGCTGAAACCGTCACTTATTCCACCCGATTGGGAGAGCAGCGTCTCATCTCCCTAGCGGATGGCAGCCGTATCAACA
TGAATACGGCTACCCGTCTGCACGTCCGCATTTCTTACCTGCAACGCAAAATTACGCTGGATGCGGGAGAAGCCGTTTTT
GACGTTGCACACGAAACCTGGCGTCCTTTTGTCGTGCATACAGACAAATTGCAAATCCAGGATATCGGTACCCAATTCAA
CGTACACAGACAGCAGGATGAGATCTCAGTCACGGTATTGGAAGGCGCGGTGGAAATCGATGGCGTACGTCTGGATGAAG
GATATCAGCAATACTACTCCTCTCGCAGTGATCATGCGGTCCTCCGCCCGGTCGATACCGAACAGATCGCAGCCTGGCAG
CACGGGCGGCTGATATTCCGCCAGACTCCTCTGGCAGCAGTCACAACCGAGCTGGAACGCTATCACCCGGTACACTTCAT
TTTTACTGACCCCGCCATTGCACATGAGACGCTGAGCGGAACATTCGGCACCCGTGATCTGCCACTTTTCCTCAGCAGCC
TGGAAAAGGCTTTACCAGTCAGGGTAAAAAAACTGCCGGACGGGCAAACCCTGCTGATCGACCGGATAAATAAAAAAATG
TGA

Upstream 100 bases:

>100_bases
CCATCTCAATATTTCCGAGAAAACCGTGCAACGACGTCTGGTACAGGCTATGTTGCGTTGCCACCGCAGCATGAACCGTA
TGACCGACCGGTAATACTAT

Downstream 100 bases:

>100_bases
CCAGTTCATCGTGTTTTTCACGTCTTACCAGACAGGACATCAGAAACCTTTATACCTTCCTGACTGGAGAAAAACACCAT
GAAATCTATTGCCGGATTAT

Product: putative FecR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSASGPPDEQLLKQALKWFFLLQSEHCTDEDKRKFNRWFCKNEAHQAAYTHAERLWSETDKLKETPDIPGLHEARRRRPK
HQPAGIFGWALFFLISSALMSISWLEYNAETVTYSTRLGEQRLISLADGSRINMNTATRLHVRISYLQRKITLDAGEAVF
DVAHETWRPFVVHTDKLQIQDIGTQFNVHRQQDEISVTVLEGAVEIDGVRLDEGYQQYYSSRSDHAVLRPVDTEQIAAWQ
HGRLIFRQTPLAAVTTELERYHPVHFIFTDPAIAHETLSGTFGTRDLPLFLSSLEKALPVRVKKLPDGQTLLIDRINKKM

Sequences:

>Translated_320_residues
MSASGPPDEQLLKQALKWFFLLQSEHCTDEDKRKFNRWFCKNEAHQAAYTHAERLWSETDKLKETPDIPGLHEARRRRPK
HQPAGIFGWALFFLISSALMSISWLEYNAETVTYSTRLGEQRLISLADGSRINMNTATRLHVRISYLQRKITLDAGEAVF
DVAHETWRPFVVHTDKLQIQDIGTQFNVHRQQDEISVTVLEGAVEIDGVRLDEGYQQYYSSRSDHAVLRPVDTEQIAAWQ
HGRLIFRQTPLAAVTTELERYHPVHFIFTDPAIAHETLSGTFGTRDLPLFLSSLEKALPVRVKKLPDGQTLLIDRINKKM
>Mature_319_residues
SASGPPDEQLLKQALKWFFLLQSEHCTDEDKRKFNRWFCKNEAHQAAYTHAERLWSETDKLKETPDIPGLHEARRRRPKH
QPAGIFGWALFFLISSALMSISWLEYNAETVTYSTRLGEQRLISLADGSRINMNTATRLHVRISYLQRKITLDAGEAVFD
VAHETWRPFVVHTDKLQIQDIGTQFNVHRQQDEISVTVLEGAVEIDGVRLDEGYQQYYSSRSDHAVLRPVDTEQIAAWQH
GRLIFRQTPLAAVTTELERYHPVHFIFTDPAIAHETLSGTFGTRDLPLFLSSLEKALPVRVKKLPDGQTLLIDRINKKM

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=308, Percent_Identity=25.974025974026, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 36831; Mature: 36700

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASGPPDEQLLKQALKWFFLLQSEHCTDEDKRKFNRWFCKNEAHQAAYTHAERLWSETD
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KLKETPDIPGLHEARRRRPKHQPAGIFGWALFFLISSALMSISWLEYNAETVTYSTRLGE
HHCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHCCH
QRLISLADGSRINMNTATRLHVRISYLQRKITLDAGEAVFDVAHETWRPFVVHTDKLQIQ
HHEEEECCCCEEECCCCEEEEEEEEHHHHHHEECCCHHHHHHHHHCCCCEEEECCEEEEE
DIGTQFNVHRQQDEISVTVLEGAVEIDGVRLDEGYQQYYSSRSDHAVLRPVDTEQIAAWQ
ECCCEECEECCCCCEEEEEEECCEEECCEEECHHHHHHHCCCCCCEEECCCCHHHHHHHH
HGRLIFRQTPLAAVTTELERYHPVHFIFTDPAIAHETLSGTFGTRDLPLFLSSLEKALPV
CCEEEEECCCHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCE
RVKKLPDGQTLLIDRINKKM
EEEECCCCCEEEEEHHCCCC
>Mature Secondary Structure 
SASGPPDEQLLKQALKWFFLLQSEHCTDEDKRKFNRWFCKNEAHQAAYTHAERLWSETD
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KLKETPDIPGLHEARRRRPKHQPAGIFGWALFFLISSALMSISWLEYNAETVTYSTRLGE
HHCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHCCH
QRLISLADGSRINMNTATRLHVRISYLQRKITLDAGEAVFDVAHETWRPFVVHTDKLQIQ
HHEEEECCCCEEECCCCEEEEEEEEHHHHHHEECCCHHHHHHHHHCCCCEEEECCEEEEE
DIGTQFNVHRQQDEISVTVLEGAVEIDGVRLDEGYQQYYSSRSDHAVLRPVDTEQIAAWQ
ECCCEECEECCCCCEEEEEEECCEEECCEEECHHHHHHHCCCCCCEEECCCCHHHHHHHH
HGRLIFRQTPLAAVTTELERYHPVHFIFTDPAIAHETLSGTFGTRDLPLFLSSLEKALPV
CCEEEEECCCHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCE
RVKKLPDGQTLLIDRINKKM
EEEECCCCCEEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]