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The map label for this gene is plsC [C]

Identifier: 114331841

GI number: 114331841

Start: 1978211

End: 1978939

Strand: Reverse

Name: plsC [C]

Synonym: Neut_1866

Alternate gene names: 114331841

Gene position: 1978939-1978211 (Counterclockwise)

Preceding gene: 114331842

Following gene: 114331839

Centisome position: 74.37

GC content: 53.36

Gene sequence:

>729_bases
ATGGCTGGTTTACGTTCCCTGATTTATATGCTGCTGCAGGCGATCATCACGCCACCATATGCGCTATTTGCCTTGGCATG
TTTTCCGCTACCTCCGCATCGCCGCTATCAGGTCACCTATGGCTGGACCAGACTGATGTTGTTCATGCTGCGCACCATTT
GTGGCCTACGTTATGAAGTGCTGGGACGGGAAAACATTCCGGTGCAGCCGTCAATTATTCTTTCCAAACATCAATCCGCC
TGGGAAACACTGGCCTTGCAGCAGATTTTTCCGCCACAGGTATGGGTGCTCAAAAAAGAACTATTGCGTATTCCATTCTT
TGGCTGGGGGCTGGCCATGACCAGCCCGATTGCAATCGACCGCAGTGCCGGTAAGGCGGCGTTGGAGCAGATCGTGGAGC
AGGGGAGGGAGCGGTTACAACAGAATTTCTGGATCGTCGTCTTTCCTGAAGGGACGCGCATCCCGCCGGGTAAAAAAGGT
AAATACCGTATCGGCGGTGCCTGGCTGGCGGTGCATACGGGTGCACTGGCTGTGCCGGTAGCGCATAACGCTGGACAATT
CTGGGGCAGAAATTCCTTCATCAAATATCCCGGCACCATTACTCTGAGCATTGGCAAGCCGATCGATCCAAACGGAATCG
AAGCTGGCGAACTGATGGCCCGGGTGGAAGCATGGATCGAAGCCGAAACCACGCGCATCAGTTGTTCAGTAAACAGACCA
ATCAAATAA

Upstream 100 bases:

>100_bases
AGGGCCAGGCCACGCTGGCGAACGACGATCTGCCTGTGGGAACGCAAATTTACCCGGATCTTTCGGCAGTGGTGGACAGT
CTCGAAATACAGGCACTGTA

Downstream 100 bases:

>100_bases
TTAAGTAGTCCCCAGCTTTGTCGGGGATTATTTAATTTATACCGCTTTCCACAGGTCTAAACACCGTACCACAACGTAAG
CATTGGAACTTTTTGTGCCA

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Phosphoserine Phosphatase; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAGLRSLIYMLLQAIITPPYALFALACFPLPPHRRYQVTYGWTRLMLFMLRTICGLRYEVLGRENIPVQPSIILSKHQSA
WETLALQQIFPPQVWVLKKELLRIPFFGWGLAMTSPIAIDRSAGKAALEQIVEQGRERLQQNFWIVVFPEGTRIPPGKKG
KYRIGGAWLAVHTGALAVPVAHNAGQFWGRNSFIKYPGTITLSIGKPIDPNGIEAGELMARVEAWIEAETTRISCSVNRP
IK

Sequences:

>Translated_242_residues
MAGLRSLIYMLLQAIITPPYALFALACFPLPPHRRYQVTYGWTRLMLFMLRTICGLRYEVLGRENIPVQPSIILSKHQSA
WETLALQQIFPPQVWVLKKELLRIPFFGWGLAMTSPIAIDRSAGKAALEQIVEQGRERLQQNFWIVVFPEGTRIPPGKKG
KYRIGGAWLAVHTGALAVPVAHNAGQFWGRNSFIKYPGTITLSIGKPIDPNGIEAGELMARVEAWIEAETTRISCSVNRP
IK
>Mature_241_residues
AGLRSLIYMLLQAIITPPYALFALACFPLPPHRRYQVTYGWTRLMLFMLRTICGLRYEVLGRENIPVQPSIILSKHQSAW
ETLALQQIFPPQVWVLKKELLRIPFFGWGLAMTSPIAIDRSAGKAALEQIVEQGRERLQQNFWIVVFPEGTRIPPGKKGK
YRIGGAWLAVHTGALAVPVAHNAGQFWGRNSFIKYPGTITLSIGKPIDPNGIEAGELMARVEAWIEAETTRISCSVNRPI
K

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=180, Percent_Identity=27.2222222222222, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5453718, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15100175, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=133, Percent_Identity=33.8345864661654, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 27189; Mature: 27058

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLRSLIYMLLQAIITPPYALFALACFPLPPHRRYQVTYGWTRLMLFMLRTICGLRYEV
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCEEEE
LGRENIPVQPSIILSKHQSAWETLALQQIFPPQVWVLKKELLRIPFFGWGLAMTSPIAID
CCCCCCCCCCHHEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECHHHHCCCEEEE
RSAGKAALEQIVEQGRERLQQNFWIVVFPEGTRIPPGKKGKYRIGGAWLAVHTGALAVPV
CCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEECCEEEEEECCEEEEEE
AHNAGQFWGRNSFIKYPGTITLSIGKPIDPNGIEAGELMARVEAWIEAETTRISCSVNRP
ECCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCC
IK
CC
>Mature Secondary Structure 
AGLRSLIYMLLQAIITPPYALFALACFPLPPHRRYQVTYGWTRLMLFMLRTICGLRYEV
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCEEEE
LGRENIPVQPSIILSKHQSAWETLALQQIFPPQVWVLKKELLRIPFFGWGLAMTSPIAID
CCCCCCCCCCHHEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECHHHHCCCEEEE
RSAGKAALEQIVEQGRERLQQNFWIVVFPEGTRIPPGKKGKYRIGGAWLAVHTGALAVPV
CCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEECCEEEEEECCEEEEEE
AHNAGQFWGRNSFIKYPGTITLSIGKPIDPNGIEAGELMARVEAWIEAETTRISCSVNRP
ECCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCC
IK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA