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The map label for this gene is gmhB [H]

Identifier: 114331842

GI number: 114331842

Start: 1978939

End: 1979481

Strand: Reverse

Name: gmhB [H]

Synonym: Neut_1867

Alternate gene names: 114331842

Gene position: 1979481-1978939 (Counterclockwise)

Preceding gene: 114331843

Following gene: 114331841

Centisome position: 74.39

GC content: 53.96

Gene sequence:

>543_bases
ATGAAGTTGATTATTCTCGACCAGAATGGTGTCATTAATCAGCGGGGTGATACGCTTATCAAGACGCCTGATGAGTGGAA
ACCGATGACAGGCAGCTTGCAAGCGATTGCGCGGCTGACTCACGCCGGTTATCGAGTGGTGACTGCCACCAATCAATCCG
GCATTGGGCGTGGTTTGCTCAACATGACTTCCTTCAATGCAATCAATGACAAGATGTTTCGTGCTGTGCAGCAGGAAGGT
GGACGGCTGGATGCCCTGTTTTTCTGCCCGCACACTCAGCATGATAAATGTGTTTGTCGCAAGCCGGGCATCGGCATGTT
CAAGGAAATCCGGCAACGCTACAGCGTTGAACTCAGCCATGTGCCCGTCGTGGGCGATTCTCTGCGCGATCTGCAGGCTG
CAGCCAAAGCAGGTGCTGTACCGGTACTGGTACTGACCGGTAAGGGCCAGGCCACGCTGGCGAACGACGATCTGCCTGTG
GGAACGCAAATTTACCCGGATCTTTCGGCAGTGGTGGACAGTCTCGAAATACAGGCACTGTAA

Upstream 100 bases:

>100_bases
ACCGTCTGGCCCTGTTGGCAGCCTTACAGGCAACGATGAATCGTGTAGCAGATATTTCCCGGCTAGCTGCCTGAATGACT
TGAGAATGCATAGTAAATAA

Downstream 100 bases:

>100_bases
TGGCTGGTTTACGTTCCCTGATTTATATGCTGCTGCAGGCGATCATCACGCCACCATATGCGCTATTTGCCTTGGCATGT
TTTCCGCTACCTCCGCATCG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKLIILDQNGVINQRGDTLIKTPDEWKPMTGSLQAIARLTHAGYRVVTATNQSGIGRGLLNMTSFNAINDKMFRAVQQEG
GRLDALFFCPHTQHDKCVCRKPGIGMFKEIRQRYSVELSHVPVVGDSLRDLQAAAKAGAVPVLVLTGKGQATLANDDLPV
GTQIYPDLSAVVDSLEIQAL

Sequences:

>Translated_180_residues
MKLIILDQNGVINQRGDTLIKTPDEWKPMTGSLQAIARLTHAGYRVVTATNQSGIGRGLLNMTSFNAINDKMFRAVQQEG
GRLDALFFCPHTQHDKCVCRKPGIGMFKEIRQRYSVELSHVPVVGDSLRDLQAAAKAGAVPVLVLTGKGQATLANDDLPV
GTQIYPDLSAVVDSLEIQAL
>Mature_180_residues
MKLIILDQNGVINQRGDTLIKTPDEWKPMTGSLQAIARLTHAGYRVVTATNQSGIGRGLLNMTSFNAINDKMFRAVQQEG
GRLDALFFCPHTQHDKCVCRKPGIGMFKEIRQRYSVELSHVPVVGDSLRDLQAAAKAGAVPVLVLTGKGQATLANDDLPV
GTQIYPDLSAVVDSLEIQAL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=32.6797385620915, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=25.8992805755396, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 19540; Mature: 19540

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIILDQNGVINQRGDTLIKTPDEWKPMTGSLQAIARLTHAGYRVVTATNQSGIGRGLL
CEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCHH
NMTSFNAINDKMFRAVQQEGGRLDALFFCPHTQHDKCVCRKPGIGMFKEIRQRYSVELSH
HHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHCEEEEC
VPVVGDSLRDLQAAAKAGAVPVLVLTGKGQATLANDDLPVGTQIYPDLSAVVDSLEIQAL
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCEECCCHHHHHHHHCEECC
>Mature Secondary Structure
MKLIILDQNGVINQRGDTLIKTPDEWKPMTGSLQAIARLTHAGYRVVTATNQSGIGRGLL
CEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCHH
NMTSFNAINDKMFRAVQQEGGRLDALFFCPHTQHDKCVCRKPGIGMFKEIRQRYSVELSH
HHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHCEEEEC
VPVVGDSLRDLQAAAKAGAVPVLVLTGKGQATLANDDLPVGTQIYPDLSAVVDSLEIQAL
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCEECCCHHHHHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]