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The map label for this gene is corC [H]

Identifier: 114331763

GI number: 114331763

Start: 1890736

End: 1891587

Strand: Reverse

Name: corC [H]

Synonym: Neut_1786

Alternate gene names: 114331763

Gene position: 1891587-1890736 (Counterclockwise)

Preceding gene: 114331764

Following gene: 114331762

Centisome position: 71.08

GC content: 43.08

Gene sequence:

>852_bases
ATGAACGAGACCTCCCCCAAAGCTGGTTGGCTTGAGCATATCAGTACATTACTTTCGCGCAAACCGGAAGATCGTGAGCA
GTTGATTGCTTTACTGCACTCTGCTTATGAGCGTAACCTGCTTGATGCGGATGCACTGGCTATGATCGAAGGGGTGATGC
AAGTTTCGGAAATGCAAGTTCGTGACGTTATGGTTCCTCGTTCGCAAATGGATACGATTGATATTAACGAAAAACCTGAG
GAGGTTATTCCATTTGTGATTGAGACTGCCCATTCACGATTTCCTGTTACGGATGGGAGCAAAGACCAGGTTATTGGTGT
TTTACTGGCAAAGGATTTATTACGCTATTACTCAAGCAGAGAAGCATTCAACATACAGGATATACTGCGCCCGGTGATAT
ATATACCGGAATCTAAGAGGCTTAATATTCTTCTCAAGGATTTTCGCAGTAATCGTAACCATATTGCTATTGTCGTCGAT
GAATATGGCGGTGTGGCTGGGCTTGTTACGATTGAGGATGTGTTGGAGCAGATTGTTGGGGATATTGAGGACGAATATGA
TTTTGACGAGGATGACGCATATATTGTTGCGGATACAGACGGCCATTATCGTGTCAAGGCAATTGCTGAAATATCAAGTT
TTAATGAAACTTTGGGCGCATCATTCAGTGATAAGGACTTTGATACGATTGGCGGTCTTGTTATTGGCAAATTTGGCAGG
CTTCCTGAGAGCGGAGAATCAATTGTCATAGGAGATTTCAGTTTTACCGTTATGAGAGCGGATAGTCGTCGTTTGCATCT
GTTAAAAGTGGAACGTATTAAACCCGAGCTGACTGATATTGCAGATTCATAA

Upstream 100 bases:

>100_bases
TTATCACCAGGCTCAATTATCCTGACCCTTATGTCATTCAGCAGTGAAATGATATAAACGGACCAGACAAATCTTTTTTA
TTCCCGATGCTATACATTTC

Downstream 100 bases:

>100_bases
GACTAATTCAGCTTTTATAGTAAATATGGTTGAATTTATGCCAAATGATTATTTTGGATCAGGCCAAAGAAGAAATAACC
TCAGCTATATAATAACTTCA

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNETSPKAGWLEHISTLLSRKPEDREQLIALLHSAYERNLLDADALAMIEGVMQVSEMQVRDVMVPRSQMDTIDINEKPE
EVIPFVIETAHSRFPVTDGSKDQVIGVLLAKDLLRYYSSREAFNIQDILRPVIYIPESKRLNILLKDFRSNRNHIAIVVD
EYGGVAGLVTIEDVLEQIVGDIEDEYDFDEDDAYIVADTDGHYRVKAIAEISSFNETLGASFSDKDFDTIGGLVIGKFGR
LPESGESIVIGDFSFTVMRADSRRLHLLKVERIKPELTDIADS

Sequences:

>Translated_283_residues
MNETSPKAGWLEHISTLLSRKPEDREQLIALLHSAYERNLLDADALAMIEGVMQVSEMQVRDVMVPRSQMDTIDINEKPE
EVIPFVIETAHSRFPVTDGSKDQVIGVLLAKDLLRYYSSREAFNIQDILRPVIYIPESKRLNILLKDFRSNRNHIAIVVD
EYGGVAGLVTIEDVLEQIVGDIEDEYDFDEDDAYIVADTDGHYRVKAIAEISSFNETLGASFSDKDFDTIGGLVIGKFGR
LPESGESIVIGDFSFTVMRADSRRLHLLKVERIKPELTDIADS
>Mature_283_residues
MNETSPKAGWLEHISTLLSRKPEDREQLIALLHSAYERNLLDADALAMIEGVMQVSEMQVRDVMVPRSQMDTIDINEKPE
EVIPFVIETAHSRFPVTDGSKDQVIGVLLAKDLLRYYSSREAFNIQDILRPVIYIPESKRLNILLKDFRSNRNHIAIVVD
EYGGVAGLVTIEDVLEQIVGDIEDEYDFDEDDAYIVADTDGHYRVKAIAEISSFNETLGASFSDKDFDTIGGLVIGKFGR
LPESGESIVIGDFSFTVMRADSRRLHLLKVERIKPELTDIADS

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=31.0679611650485, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI40068053, Length=188, Percent_Identity=27.1276595744681, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40068055, Length=188, Percent_Identity=27.1276595744681, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI94681046, Length=192, Percent_Identity=27.6041666666667, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786879, Length=263, Percent_Identity=47.9087452471483, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI87082033, Length=264, Percent_Identity=28.030303030303, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693175, Length=261, Percent_Identity=26.0536398467433, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788119, Length=230, Percent_Identity=31.7391304347826, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790664, Length=241, Percent_Identity=24.0663900414938, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31861; Mature: 31861

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETSPKAGWLEHISTLLSRKPEDREQLIALLHSAYERNLLDADALAMIEGVMQVSEMQV
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RDVMVPRSQMDTIDINEKPEEVIPFVIETAHSRFPVTDGSKDQVIGVLLAKDLLRYYSSR
HHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
EAFNIQDILRPVIYIPESKRLNILLKDFRSNRNHIAIVVDEYGGVAGLVTIEDVLEQIVG
CCCCHHHHHHHHEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEEHHHHHHHHHH
DIEDEYDFDEDDAYIVADTDGHYRVKAIAEISSFNETLGASFSDKDFDTIGGLVIGKFGR
CCHHCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
LPESGESIVIGDFSFTVMRADSRRLHLLKVERIKPELTDIADS
CCCCCCEEEEECCEEEEEECCCCCEEEEEHHHCCCHHHHCCCC
>Mature Secondary Structure
MNETSPKAGWLEHISTLLSRKPEDREQLIALLHSAYERNLLDADALAMIEGVMQVSEMQV
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RDVMVPRSQMDTIDINEKPEEVIPFVIETAHSRFPVTDGSKDQVIGVLLAKDLLRYYSSR
HHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
EAFNIQDILRPVIYIPESKRLNILLKDFRSNRNHIAIVVDEYGGVAGLVTIEDVLEQIVG
CCCCHHHHHHHHEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEEHHHHHHHHHH
DIEDEYDFDEDDAYIVADTDGHYRVKAIAEISSFNETLGASFSDKDFDTIGGLVIGKFGR
CCHHCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
LPESGESIVIGDFSFTVMRADSRRLHLLKVERIKPELTDIADS
CCCCCCEEEEECCEEEEEECCCCCEEEEEHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]