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The map label for this gene is wecA [H]

Identifier: 113969675

GI number: 113969675

Start: 1544281

End: 1545342

Strand: Direct

Name: wecA [H]

Synonym: Shewmr4_1332

Alternate gene names: 113969675

Gene position: 1544281-1545342 (Clockwise)

Preceding gene: 113969674

Following gene: 113969676

Centisome position: 32.81

GC content: 40.11

Gene sequence:

>1062_bases
ATGGAATACCTCATACCGCTTTTAAGTGTTTTTTGTTTAACTTGTGTCGCTATCAAGATCTTAAATCCTATCGCACAGCG
TGTTGGTTTAGTTGATTTGCCCAACGAGCGTAAGTTGCATGAAGGTGCAATCCCACTGATTGGTGGGGTTTCTATTTATT
GTAGTGTCTTGCTAGTGTCGAGTGTTGTTTTGCCTGAAAGCCAAATCTTTAATTTATATCTCATTTCCGCTGCGTTAATC
CTCTTTCTTGGTGTGCTTGATGATAAGTATGATTTATCTGTACGTGTGCGGATAGCAGCCCAAGTGATTACAGCCTCTAT
TTTGATTTTTGGGGCAGGGTTATACCTTACGACATTTGGGCATATTTTGTACTTTTTTGAGTTTAAACTCGGCTATGTTG
GCATTTTTGTAACCACTGTTGCGGTGATAGGTGCTATTAACGCCTTTAATATGGTGGATGGTATTGATGGCTTAGCAGGG
ATGTTGAGTCTTGTTACCTTTTCGTCATTAGCTTTTTTGTTCTATTGGGCTGGTAATAGTTGGTTTGTACTTCCTTTACT
ATTCATTGGGGCAATAATAGGATACCTGCTGTTTAACTTGCGTTGGCCATTCGCATCTTTCGATAAGATTTTCATGGGTG
ATGCTGGCAGCATGTTGATTGGTTTAACGGTTGTTTGGTTATTGGTATTGGGCACGCAAGCTGATAGTAATCATATACAA
CAAGGACAAGTTTTCTCTCCTGTTACGGCATTGTACCTTATCGCGATCCCGTTAATGGATATGGCTGCGATTATGTACAG
AAGAGTTAAAAAAGGTATGTCGCCATTTAAACCCGATCGTGATCATTTGCATCATATTTTTGAGCGCGCGGGTTATAATC
GAAAGCAAACTTTGATCAGGATATCGCTTGCTTCACTTTTACTGGCAGTGATTGGTGTTGGCGCGGATTTGGCTCAAGTT
CCCGACTCAATTATGTTTGTTAGTTTTTTAGCTATTTTTGCGGCTTACAATTGGGCGCTTGCTAATGTGTGGCAACTTTT
GACTTGGTTTAGAAAAGAATAA

Upstream 100 bases:

>100_bases
CGGTGTCGATTCAACTGCTATAATCCAGTGTCATTTTTTTGAAATAAAATGTGATTAGTCTCATTTTGAACATGGTGTAT
TTGGCTTAAGGAAGAGAGTG

Downstream 100 bases:

>100_bases
TTGTAAGACTATTTTTGCAAAAGCCAGCTAACTTAAGCTGGCTTTTTGTTTTAATTTGATTAGGGATTTCATATGTCTAG
GAAGTATTTTGGTACCGATG

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEYLIPLLSVFCLTCVAIKILNPIAQRVGLVDLPNERKLHEGAIPLIGGVSIYCSVLLVSSVVLPESQIFNLYLISAALI
LFLGVLDDKYDLSVRVRIAAQVITASILIFGAGLYLTTFGHILYFFEFKLGYVGIFVTTVAVIGAINAFNMVDGIDGLAG
MLSLVTFSSLAFLFYWAGNSWFVLPLLFIGAIIGYLLFNLRWPFASFDKIFMGDAGSMLIGLTVVWLLVLGTQADSNHIQ
QGQVFSPVTALYLIAIPLMDMAAIMYRRVKKGMSPFKPDRDHLHHIFERAGYNRKQTLIRISLASLLLAVIGVGADLAQV
PDSIMFVSFLAIFAAYNWALANVWQLLTWFRKE

Sequences:

>Translated_353_residues
MEYLIPLLSVFCLTCVAIKILNPIAQRVGLVDLPNERKLHEGAIPLIGGVSIYCSVLLVSSVVLPESQIFNLYLISAALI
LFLGVLDDKYDLSVRVRIAAQVITASILIFGAGLYLTTFGHILYFFEFKLGYVGIFVTTVAVIGAINAFNMVDGIDGLAG
MLSLVTFSSLAFLFYWAGNSWFVLPLLFIGAIIGYLLFNLRWPFASFDKIFMGDAGSMLIGLTVVWLLVLGTQADSNHIQ
QGQVFSPVTALYLIAIPLMDMAAIMYRRVKKGMSPFKPDRDHLHHIFERAGYNRKQTLIRISLASLLLAVIGVGADLAQV
PDSIMFVSFLAIFAAYNWALANVWQLLTWFRKE
>Mature_353_residues
MEYLIPLLSVFCLTCVAIKILNPIAQRVGLVDLPNERKLHEGAIPLIGGVSIYCSVLLVSSVVLPESQIFNLYLISAALI
LFLGVLDDKYDLSVRVRIAAQVITASILIFGAGLYLTTFGHILYFFEFKLGYVGIFVTTVAVIGAINAFNMVDGIDGLAG
MLSLVTFSSLAFLFYWAGNSWFVLPLLFIGAIIGYLLFNLRWPFASFDKIFMGDAGSMLIGLTVVWLLVLGTQADSNHIQ
QGQVFSPVTALYLIAIPLMDMAAIMYRRVKKGMSPFKPDRDHLHHIFERAGYNRKQTLIRISLASLLLAVIGVGADLAQV
PDSIMFVSFLAIFAAYNWALANVWQLLTWFRKE

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=330, Percent_Identity=44.8484848484849, Blast_Score=254, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012750
- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39076; Mature: 39076

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLIPLLSVFCLTCVAIKILNPIAQRVGLVDLPNERKLHEGAIPLIGGVSIYCSVLLVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHH
SVVLPESQIFNLYLISAALILFLGVLDDKYDLSVRVRIAAQVITASILIFGAGLYLTTFG
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
HILYFFEFKLGYVGIFVTTVAVIGAINAFNMVDGIDGLAGMLSLVTFSSLAFLFYWAGNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WFVLPLLFIGAIIGYLLFNLRWPFASFDKIFMGDAGSMLIGLTVVWLLVLGTQADSNHIQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
QGQVFSPVTALYLIAIPLMDMAAIMYRRVKKGMSPFKPDRDHLHHIFERAGYNRKQTLIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
ISLASLLLAVIGVGADLAQVPDSIMFVSFLAIFAAYNWALANVWQLLTWFRKE
HHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYLIPLLSVFCLTCVAIKILNPIAQRVGLVDLPNERKLHEGAIPLIGGVSIYCSVLLVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHH
SVVLPESQIFNLYLISAALILFLGVLDDKYDLSVRVRIAAQVITASILIFGAGLYLTTFG
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
HILYFFEFKLGYVGIFVTTVAVIGAINAFNMVDGIDGLAGMLSLVTFSSLAFLFYWAGNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WFVLPLLFIGAIIGYLLFNLRWPFASFDKIFMGDAGSMLIGLTVVWLLVLGTQADSNHIQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
QGQVFSPVTALYLIAIPLMDMAAIMYRRVKKGMSPFKPDRDHLHHIFERAGYNRKQTLIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
ISLASLLLAVIGVGADLAQVPDSIMFVSFLAIFAAYNWALANVWQLLTWFRKE
HHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]