Click here to switch to the map view.

The map label for this gene is wecA [H]

Identifier: 113969674

GI number: 113969674

Start: 1543063

End: 1544136

Strand: Direct

Name: wecA [H]

Synonym: Shewmr4_1331

Alternate gene names: 113969674

Gene position: 1543063-1544136 (Clockwise)

Preceding gene: 113969673

Following gene: 113969675

Centisome position: 32.79

GC content: 42.36

Gene sequence:

>1074_bases
ATGTCAGCAAACATCGCTGTTTTATTTACTTTTCTAATTTCTTTTATCAGTTTGTTTGTATTTCGCAAGGTCGCTCAACG
AATTGGTTTGGTCGATAAACCGAATGAGCGTAAACACCATACTGGCCAAATCCCCTTGGTCGGTGGGGTGAGCGTATTTA
TGACCATGATGTTGGTGTTGTGGCTTATTCCAACGCTGTTAATTGAACCGGTTTTGTATGCGAGCTGCGCCTTTATTCTT
GTGGTTATTGGTGCGATTGATGACCGCTTCGATATTAGCTTTAAACTTCGGCTAGTGGTTCAGGCGCTTATATCACTGTT
AATGATCGTGATAGGAGAGCGCAGTTTATATAATTTAGGCTACTTGATGGGCAGCGAGGCGATATATTTGCCCGAGCCTA
TTAGTATTTTGCTGACTATCTTTGCGGTTATTGGTGCGATAAATGCCTTTAATATGGTCGATGGCATTGACGGCTTGCTG
GGCGGTTTAGCGTCTGTCACTTTTGGCGGCTTAGGTATTTTATTTTATCTGCATGGTATGTATGGTTTTGCTATTTTTTG
TGGTTTGCTGGTTACAGCGATGCTGCCTTACATCATGCTTAATTTAGGCTTTCCGTTCGGGCGACGTTTTAAGGTGTTCA
TGGGCGATGCGGGGAGCATTTTTATCGGCTTTACTGTCATTTGGCTGCTGATTGTGGCCAGTCAGGGTGAGCGAGCTACC
GCCATTCGCCCGGTTACCGCATTGTGGCTAATTGCTTTACCGCTGATGGATATGGTGTGCATCATGATCCGCCGTATTCG
TAAAGGCCAATCGCCATTTAAACCCGACCGAGAGCATTTACACCATATTTGTCAACGTCTTGGATTAACCTCCCATATGT
CACTTATGATGATTTGCACAGCTGCAGGGACTATGGCAGCCATTGGTATTTGGTCTGAGCTTGCTAAAATAGATGAAAAT
ATTATGTTTTATGCATTTTTGGCTACTTTTGCTTGTTATTTTACGATAATGAATAACATTTGGCGTATTACTGCATTTTT
GCGTAGAGACGTAAAGTTTTTTAAATCAATTTAA

Upstream 100 bases:

>100_bases
CCCTTTTTCCAGGCTCGCGACTCCTTAGTTTCCGCTTTATAGGCCAGGCTCCCGACTTTTTAGTCCCTAGTCCCTAGTCC
CAGCTTTTTAGAGTTTTGTT

Downstream 100 bases:

>100_bases
TACGTTAGTGAAATTGTTAGATTTTTAGCTTTTAGGTGCTTATCCGGTGTCGATTCAACTGCTATAATCCAGTGTCATTT
TTTTGAAATAAAATGTGATT

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSANIAVLFTFLISFISLFVFRKVAQRIGLVDKPNERKHHTGQIPLVGGVSVFMTMMLVLWLIPTLLIEPVLYASCAFIL
VVIGAIDDRFDISFKLRLVVQALISLLMIVIGERSLYNLGYLMGSEAIYLPEPISILLTIFAVIGAINAFNMVDGIDGLL
GGLASVTFGGLGILFYLHGMYGFAIFCGLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGERAT
AIRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRLGLTSHMSLMMICTAAGTMAAIGIWSELAKIDEN
IMFYAFLATFACYFTIMNNIWRITAFLRRDVKFFKSI

Sequences:

>Translated_357_residues
MSANIAVLFTFLISFISLFVFRKVAQRIGLVDKPNERKHHTGQIPLVGGVSVFMTMMLVLWLIPTLLIEPVLYASCAFIL
VVIGAIDDRFDISFKLRLVVQALISLLMIVIGERSLYNLGYLMGSEAIYLPEPISILLTIFAVIGAINAFNMVDGIDGLL
GGLASVTFGGLGILFYLHGMYGFAIFCGLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGERAT
AIRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRLGLTSHMSLMMICTAAGTMAAIGIWSELAKIDEN
IMFYAFLATFACYFTIMNNIWRITAFLRRDVKFFKSI
>Mature_356_residues
SANIAVLFTFLISFISLFVFRKVAQRIGLVDKPNERKHHTGQIPLVGGVSVFMTMMLVLWLIPTLLIEPVLYASCAFILV
VIGAIDDRFDISFKLRLVVQALISLLMIVIGERSLYNLGYLMGSEAIYLPEPISILLTIFAVIGAINAFNMVDGIDGLLG
GLASVTFGGLGILFYLHGMYGFAIFCGLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGERATA
IRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRLGLTSHMSLMMICTAAGTMAAIGIWSELAKIDENI
MFYAFLATFACYFTIMNNIWRITAFLRRDVKFFKSI

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=328, Percent_Identity=50.609756097561, Blast_Score=313, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012750
- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39836; Mature: 39705

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANIAVLFTFLISFISLFVFRKVAQRIGLVDKPNERKHHTGQIPLVGGVSVFMTMMLVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
WLIPTLLIEPVLYASCAFILVVIGAIDDRFDISFKLRLVVQALISLLMIVIGERSLYNLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YLMGSEAIYLPEPISILLTIFAVIGAINAFNMVDGIDGLLGGLASVTFGGLGILFYLHGM
HHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGFAIFCGLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGERAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCH
AIRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRLGLTSHMSLMMICT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AAGTMAAIGIWSELAKIDENIMFYAFLATFACYFTIMNNIWRITAFLRRDVKFFKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SANIAVLFTFLISFISLFVFRKVAQRIGLVDKPNERKHHTGQIPLVGGVSVFMTMMLVL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
WLIPTLLIEPVLYASCAFILVVIGAIDDRFDISFKLRLVVQALISLLMIVIGERSLYNLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YLMGSEAIYLPEPISILLTIFAVIGAINAFNMVDGIDGLLGGLASVTFGGLGILFYLHGM
HHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGFAIFCGLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGERAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCH
AIRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRLGLTSHMSLMMICT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AAGTMAAIGIWSELAKIDENIMFYAFLATFACYFTIMNNIWRITAFLRRDVKFFKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]