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The map label for this gene is fhuE [H]

Identifier: 113969294

GI number: 113969294

Start: 1110440

End: 1112611

Strand: Direct

Name: fhuE [H]

Synonym: Shewmr4_0950

Alternate gene names: 113969294

Gene position: 1110440-1112611 (Clockwise)

Preceding gene: 113969293

Following gene: 113969295

Centisome position: 23.59

GC content: 48.25

Gene sequence:

>2172_bases
ATGACTATGCGTTTTAATCTACTTCCACTTGCTGCTGCAGTAACCCTAGCTTTGAATCCTTTGGCGCTGATGGCCGAAGA
ACAAACCGCTTCAACAACAGAGACACAAGATCAAAATATCGAAAAAATCACTGTGATGGGTAAATACACAGTGAGTCGTA
ATATTGATACCGCAACGGGGTTAGGACTCACGCTGCGGGAAACGCCACAGTCGGTCAGCATTATGACAGCGGATCGGATT
GAAGATCAGGCGCTAAATACCGTGGTCGATGTGGTCAACAACACTGTGGGTTTATCATCCTCAAAAACCGATAACGTGCG
TAACGGTTTTTCGGCCCGCGGTTTTACCGTGCAAAACTATCAAATTGATGGCGTGCCTTTATCTTGGAGTTTAGGTGGTG
ATGCAGGTGAAACGGTATCGGATGTGTCTATCTACGAGCGCGTTGAAGTCGTGCGTGGTGCTACCGGATTATTAACGGGT
GCTGGCGATCCTTCGGCCTCGATTAACTTAGTGCGTAAGCATGCCGACAGTTCTGATCTTAAAGGTTATGTGGATGTCGC
CACTGGAAGTTGGGATAAAAAACAAGTCACCGCGGATGTGTCTAATGGTCTGAATGAAGACGGCAGCGTGCGTGGGCGCT
TGGTCGCTAAGTATGTGAATAGCGATTCTTACCAAGATCTGTATCAAGACCGCAAAACCATTCTCTATGGTGTGGTCGAC
AGTGATATTACGGCCAACACCTTGCTGCGCGTCGGTGGTAGCTATAACCACAACGATCCCAAAGGGGCGATGTGGGGCGC
GTTGCCTGCCGTCTTTAGTGATGGTTCTGCCACTGATTGGGATACATCGGCCACCACAGCTGCCGATTGGAGCCGCTGGG
AAACCAAAAACATCAACTACTTTGCGAACCTGAATCACTACTTCAGCAATGGTTGGCAGCTGGTCGCTAACTACAACCGC
ATGGAGTATGAGACCACCACTAAGATGATCTACATGTCGGGTATGCTCGATAAAGACACGGGGGTGGGACTCAGTGGACA
GCGTTATCACAGCCATGGTGAAAGTAACTCGAATAACTTTGATGTGCAGCTAAAGGGCGACTATGACCTCTTTGGTCAAA
CCCATGAGTTTGTGACGGGCGCTTTGTATAGTAAGCAAAAATCCTACGCCGATACCTATGAGCCTATCCGTGACGATATG
ACGGGGTGGGACTCACAAGTGGTGGATAACTTCTACGAATGGCAACAAAATCAGTTTGCCGAGCCAGAATGGTCGAGCAA
CGCGAACCGTCAGCTCAATATGGATACCGAGCAAAAAGGCTTTTATGCGGCGACTCGCTTAACGATTACCGATGATTTTA
AACTGATTGCCGGTGGACGTATCTCAAGCTGGAACCGTGAAGGCGTGAGCTATGGTACCGATACTAACTTTGGTGATGAT
GGGGTGTTTGTGCCCTATGTTGGCGCCTTGTACGATATCAATGACGCGCACCGTATTTACGCCAGTTATACCGGGATTTT
TAACCCGCAGAATAATTTCGATGCCGATCAAAATTACCTCGACCCATTAGAAGGCAAAGCCTACGAATTAGGTCTGAAGA
GTGCTTATCTTGACGATCGTCTACATACCACTGTGGCCGTGTTCCAAATTGACCAAGATAACTTGGCAACCTTAGCCGGA
ACGATTGTTATCGGTGGTCAACCCGTGAATTATTATGAGGCCGCACAAGGCACTAAGAGTAAGGGATTTGAGCTAGAGGT
GGTGGGTGAGCCTGCCGATGGCTGGAATATCTCTGCGGGTTACTCGCAATTTAATGCCGAAGATGCAGAGGGTAAGCGGG
TTGCGACTACCAGTCCGCAGAAGCAATTCAAACTGTTTACCACCTACCAATTTGTGGACTTATTGCCTGAGTTAACCATA
GGTGGTGGGGTGAATTGGCAAAGCGACAGTTACTCTGAAGGCGGTGGTGTGGCAATCAAGCAGGATGCTTACTCCCTAGT
GAATCTGATGGCACGCTACGATCTGGCTGAGAATATGGATCTGCAGGTTAACGTAGAGAATCTGCTGGATGAGAAATATT
ATGCCTATATGACAGCGTCTGGCATTGCTTACAGTGCGTATCACTACGGCGCGCCACGTAATTTTACCGTCAGCTTTAAC
TATCGTTTTTAA

Upstream 100 bases:

>100_bases
GACTTAATAATGATAAATTTGTTACATTTATCACATAAATCATAAATGCAAATCGTTCTCAATAGTGTTACCGTGTGTGC
ACCTTAACAAAATTTGCTAA

Downstream 100 bases:

>100_bases
GCATTTTACCCGTTGAACTCAAAAAGCCGGCGCCCTTAAGAGCGTCGGCTTTTTGCTATCGACTTCAATCCCATTTGCGG
CGCTGACGTTGCCTTATATG

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MTMRFNLLPLAAAVTLALNPLALMAEEQTASTTETQDQNIEKITVMGKYTVSRNIDTATGLGLTLRETPQSVSIMTADRI
EDQALNTVVDVVNNTVGLSSSKTDNVRNGFSARGFTVQNYQIDGVPLSWSLGGDAGETVSDVSIYERVEVVRGATGLLTG
AGDPSASINLVRKHADSSDLKGYVDVATGSWDKKQVTADVSNGLNEDGSVRGRLVAKYVNSDSYQDLYQDRKTILYGVVD
SDITANTLLRVGGSYNHNDPKGAMWGALPAVFSDGSATDWDTSATTAADWSRWETKNINYFANLNHYFSNGWQLVANYNR
MEYETTTKMIYMSGMLDKDTGVGLSGQRYHSHGESNSNNFDVQLKGDYDLFGQTHEFVTGALYSKQKSYADTYEPIRDDM
TGWDSQVVDNFYEWQQNQFAEPEWSSNANRQLNMDTEQKGFYAATRLTITDDFKLIAGGRISSWNREGVSYGTDTNFGDD
GVFVPYVGALYDINDAHRIYASYTGIFNPQNNFDADQNYLDPLEGKAYELGLKSAYLDDRLHTTVAVFQIDQDNLATLAG
TIVIGGQPVNYYEAAQGTKSKGFELEVVGEPADGWNISAGYSQFNAEDAEGKRVATTSPQKQFKLFTTYQFVDLLPELTI
GGGVNWQSDSYSEGGGVAIKQDAYSLVNLMARYDLAENMDLQVNVENLLDEKYYAYMTASGIAYSAYHYGAPRNFTVSFN
YRF

Sequences:

>Translated_723_residues
MTMRFNLLPLAAAVTLALNPLALMAEEQTASTTETQDQNIEKITVMGKYTVSRNIDTATGLGLTLRETPQSVSIMTADRI
EDQALNTVVDVVNNTVGLSSSKTDNVRNGFSARGFTVQNYQIDGVPLSWSLGGDAGETVSDVSIYERVEVVRGATGLLTG
AGDPSASINLVRKHADSSDLKGYVDVATGSWDKKQVTADVSNGLNEDGSVRGRLVAKYVNSDSYQDLYQDRKTILYGVVD
SDITANTLLRVGGSYNHNDPKGAMWGALPAVFSDGSATDWDTSATTAADWSRWETKNINYFANLNHYFSNGWQLVANYNR
MEYETTTKMIYMSGMLDKDTGVGLSGQRYHSHGESNSNNFDVQLKGDYDLFGQTHEFVTGALYSKQKSYADTYEPIRDDM
TGWDSQVVDNFYEWQQNQFAEPEWSSNANRQLNMDTEQKGFYAATRLTITDDFKLIAGGRISSWNREGVSYGTDTNFGDD
GVFVPYVGALYDINDAHRIYASYTGIFNPQNNFDADQNYLDPLEGKAYELGLKSAYLDDRLHTTVAVFQIDQDNLATLAG
TIVIGGQPVNYYEAAQGTKSKGFELEVVGEPADGWNISAGYSQFNAEDAEGKRVATTSPQKQFKLFTTYQFVDLLPELTI
GGGVNWQSDSYSEGGGVAIKQDAYSLVNLMARYDLAENMDLQVNVENLLDEKYYAYMTASGIAYSAYHYGAPRNFTVSFN
YRF
>Mature_722_residues
TMRFNLLPLAAAVTLALNPLALMAEEQTASTTETQDQNIEKITVMGKYTVSRNIDTATGLGLTLRETPQSVSIMTADRIE
DQALNTVVDVVNNTVGLSSSKTDNVRNGFSARGFTVQNYQIDGVPLSWSLGGDAGETVSDVSIYERVEVVRGATGLLTGA
GDPSASINLVRKHADSSDLKGYVDVATGSWDKKQVTADVSNGLNEDGSVRGRLVAKYVNSDSYQDLYQDRKTILYGVVDS
DITANTLLRVGGSYNHNDPKGAMWGALPAVFSDGSATDWDTSATTAADWSRWETKNINYFANLNHYFSNGWQLVANYNRM
EYETTTKMIYMSGMLDKDTGVGLSGQRYHSHGESNSNNFDVQLKGDYDLFGQTHEFVTGALYSKQKSYADTYEPIRDDMT
GWDSQVVDNFYEWQQNQFAEPEWSSNANRQLNMDTEQKGFYAATRLTITDDFKLIAGGRISSWNREGVSYGTDTNFGDDG
VFVPYVGALYDINDAHRIYASYTGIFNPQNNFDADQNYLDPLEGKAYELGLKSAYLDDRLHTTVAVFQIDQDNLATLAGT
IVIGGQPVNYYEAAQGTKSKGFELEVVGEPADGWNISAGYSQFNAEDAEGKRVATTSPQKQFKLFTTYQFVDLLPELTIG
GGVNWQSDSYSEGGGVAIKQDAYSLVNLMARYDLAENMDLQVNVENLLDEKYYAYMTASGIAYSAYHYGAPRNFTVSFNY
RF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=733, Percent_Identity=38.3356070941337, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1786344, Length=729, Percent_Identity=25.6515775034294, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1787024, Length=347, Percent_Identity=27.0893371757925, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79870; Mature: 79739

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRFNLLPLAAAVTLALNPLALMAEEQTASTTETQDQNIEKITVMGKYTVSRNIDTATG
CCEEEECHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
LGLTLRETPQSVSIMTADRIEDQALNTVVDVVNNTVGLSSSKTDNVRNGFSARGFTVQNY
CCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEE
QIDGVPLSWSLGGDAGETVSDVSIYERVEVVRGATGLLTGAGDPSASINLVRKHADSSDL
EECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEHEEECCCCCCC
KGYVDVATGSWDKKQVTADVSNGLNEDGSVRGRLVAKYVNSDSYQDLYQDRKTILYGVVD
CEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEEEEEEC
SDITANTLLRVGGSYNHNDPKGAMWGALPAVFSDGSATDWDTSATTAADWSRWETKNINY
CCCCHHHHHEECCCCCCCCCCCCHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
FANLNHYFSNGWQLVANYNRMEYETTTKMIYMSGMLDKDTGVGLSGQRYHSHGESNSNNF
EECCCHHHCCCEEEEECCCCEEEEHHEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCEE
DVQLKGDYDLFGQTHEFVTGALYSKQKSYADTYEPIRDDMTGWDSQVVDNFYEWQQNQFA
EEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
EPEWSSNANRQLNMDTEQKGFYAATRLTITDDFKLIAGGRISSWNREGVSYGTDTNFGDD
CCCCCCCCCCEECCCCCCCCEEEEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCC
GVFVPYVGALYDINDAHRIYASYTGIFNPQNNFDADQNYLDPLEGKAYELGLKSAYLDDR
CEECCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCC
LHTTVAVFQIDQDNLATLAGTIVIGGQPVNYYEAAQGTKSKGFELEVVGEPADGWNISAG
CEEEEEEEEECCCCCEEEEEEEEECCCCCCHHHHCCCCCCCCEEEEEEECCCCCCEEECC
YSQFNAEDAEGKRVATTSPQKQFKLFTTYQFVDLLPELTIGGGVNWQSDSYSEGGGVAIK
CCCCCCCCCCCCEEECCCCHHHEEEEEHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEE
QDAYSLVNLMARYDLAENMDLQVNVENLLDEKYYAYMTASGIAYSAYHYGAPRNFTVSFN
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCEEEEEEECCEEEEEEECCCCCEEEEEEE
YRF
ECC
>Mature Secondary Structure 
TMRFNLLPLAAAVTLALNPLALMAEEQTASTTETQDQNIEKITVMGKYTVSRNIDTATG
CEEEECHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
LGLTLRETPQSVSIMTADRIEDQALNTVVDVVNNTVGLSSSKTDNVRNGFSARGFTVQNY
CCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEE
QIDGVPLSWSLGGDAGETVSDVSIYERVEVVRGATGLLTGAGDPSASINLVRKHADSSDL
EECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEHEEECCCCCCC
KGYVDVATGSWDKKQVTADVSNGLNEDGSVRGRLVAKYVNSDSYQDLYQDRKTILYGVVD
CEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEEEEEEC
SDITANTLLRVGGSYNHNDPKGAMWGALPAVFSDGSATDWDTSATTAADWSRWETKNINY
CCCCHHHHHEECCCCCCCCCCCCHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
FANLNHYFSNGWQLVANYNRMEYETTTKMIYMSGMLDKDTGVGLSGQRYHSHGESNSNNF
EECCCHHHCCCEEEEECCCCEEEEHHEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCEE
DVQLKGDYDLFGQTHEFVTGALYSKQKSYADTYEPIRDDMTGWDSQVVDNFYEWQQNQFA
EEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
EPEWSSNANRQLNMDTEQKGFYAATRLTITDDFKLIAGGRISSWNREGVSYGTDTNFGDD
CCCCCCCCCCEECCCCCCCCEEEEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCC
GVFVPYVGALYDINDAHRIYASYTGIFNPQNNFDADQNYLDPLEGKAYELGLKSAYLDDR
CEECCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCC
LHTTVAVFQIDQDNLATLAGTIVIGGQPVNYYEAAQGTKSKGFELEVVGEPADGWNISAG
CEEEEEEEEECCCCCEEEEEEEEECCCCCCHHHHCCCCCCCCEEEEEEECCCCCCEEECC
YSQFNAEDAEGKRVATTSPQKQFKLFTTYQFVDLLPELTIGGGVNWQSDSYSEGGGVAIK
CCCCCCCCCCCCEEECCCCHHHEEEEEHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEE
QDAYSLVNLMARYDLAENMDLQVNVENLLDEKYYAYMTASGIAYSAYHYGAPRNFTVSFN
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCEEEEEEECCEEEEEEECCCCCEEEEEEE
YRF
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]