Click here to switch to the map view.

The map label for this gene is purP [H]

Identifier: 113969295

GI number: 113969295

Start: 1113020

End: 1114309

Strand: Direct

Name: purP [H]

Synonym: Shewmr4_0951

Alternate gene names: 113969295

Gene position: 1113020-1114309 (Clockwise)

Preceding gene: 113969294

Following gene: 113969296

Centisome position: 23.65

GC content: 49.46

Gene sequence:

>1290_bases
ATGTTAGAAAAGCTGTTCAAACTGAAACAAAATCAAACGAGCCTCAAGCAGGAAGCGATAGCAGGTTTGACAACATTTAT
GACTATGGCCTACATCATTTTTGTGAATCCAATGATGTTAGCCGATGCGGGTATGGATCATGGCGCCGTGTTTGTGGCCA
CCTGTTTAGCGGCGGCGGTGGGATGTATTGTGATGGGTGTGATGGCGAACTACCCCATTGCACTGGCCCCTGGTATGGGA
CTCAATGCTTTTTTTACCTACACAGTAGTGGGTGAGATGGGTTATAGCTGGGAAACTGCACTTGGTGCTGTTTTCCTGTC
GGGAATTTGCTTTTTAATCCTGTCTCTAGTGCGTATTCGCGAGTGGATTGTGAACAGCATTCCTATGTCGCTGCGTATCG
GTATTGCTGCGGGTATTGGCTTATTCCTCGCGCTGATCGGTCTTAAGAGTGCTGGCATTGTGGTCGCAAGTCCTGCAACT
TTAGTGACTATGGGCGATATTACCGCTTTCCCGGCGGTGATGGCCGTGTTAGGTTTCTTCCTGATCATCGCCATGGTGCA
ACGTGGAATGAAATCGGCGGTGATTTTAAGCATCCTTATCATTACTGGGCTTGGGTTACTCTTCGGTGATGTGCATTACA
ACGGTATCGTCTCTATGCCGCCTTCTGTCGCGCCGACCTTTATGGCGATGGATTTATCCCAAGTATTTGAAGTAACAATG
CTATCCGTGGTGTTTGCCTTCCTATTTGTCGATCTCTTTGATACTTCGGGCACCTTAGTTGCGGTTGCGCAGCGCGGTGG
TTTCCTCGATGAAAAAGGCCGTTTACCTCGCTTAAACCGTGCCTTAACCGCCGACAGTTTAGCGACGATTGCGGGCGCTG
CATTCGGTACGTCAACCACCACTAGTTATATCGAAAGTACCGCTGGGGTGAGCGCGGGCGGCCGTACTGGCTTAACCGCT
GTCGTTGTCGGCTTACTGTTCATCTTGGCCTTATTCTTATCACCATTAGCTGGAATGATCCCCGCCTATGCTACGGCTGG
TACCTTGTTCTATGTGGCGATTCTAATGATGGCTGGACTGGTTCACGTTGAATGGGAAGACTTAACTGAGGCTGCACCTG
TGGTTGTGGTGTGTATCCTGATGCCGCTGACCTTCTCAATTGCCACAGGGATTGCGCTGGGGATTATTTCCTATGCTGTC
ATCAAGCTGTTAACGGGCCGCTTTAGCGATTTAAATATCGGCGTGCTGGTGCTCGCTGCCATGTTTATTGCGAAATTTAT
TTACGGCTGA

Upstream 100 bases:

>100_bases
TGACCAGCACAAACTCCCTATAATCCCCTGCGAAAAACACGACTACATAGTGTTTACATTTTTGACCCTACCTACTTAAA
AAGAAAAGGAACCCAGTTCC

Downstream 100 bases:

>100_bases
TACTGAGCTAGTCGTCCATTCGCGGGCTATTTTTTGAGGGGCATCTAATCGATGGCCCTTTTTTATGCGCGATCCCAAGC
AGAATTGAAAATTTCTACCA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCIVMGVMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPAT
LVTMGDITAFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLLFGDVHYNGIVSMPPSVAPTFMAMDLSQVFEVTM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFILALFLSPLAGMIPAYATAGTLFYVAILMMAGLVHVEWEDLTEAAPVVVVCILMPLTFSIATGIALGIISYAV
IKLLTGRFSDLNIGVLVLAAMFIAKFIYG

Sequences:

>Translated_429_residues
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCIVMGVMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPAT
LVTMGDITAFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLLFGDVHYNGIVSMPPSVAPTFMAMDLSQVFEVTM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFILALFLSPLAGMIPAYATAGTLFYVAILMMAGLVHVEWEDLTEAAPVVVVCILMPLTFSIATGIALGIISYAV
IKLLTGRFSDLNIGVLVLAAMFIAKFIYG
>Mature_429_residues
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCIVMGVMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPAT
LVTMGDITAFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLLFGDVHYNGIVSMPPSVAPTFMAMDLSQVFEVTM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFILALFLSPLAGMIPAYATAGTLFYVAILMMAGLVHVEWEDLTEAAPVVVVCILMPLTFSIATGIALGIISYAV
IKLLTGRFSDLNIGVLVLAAMFIAKFIYG

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=52.5700934579439, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI87082309, Length=426, Percent_Identity=50, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790499, Length=425, Percent_Identity=38.3529411764706, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=37.9310344827586, Blast_Score=265, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45034; Mature: 45034

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GCIVMGVMANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPATLVTMGDITAFPAVMAVLGFF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECHHHHHHHHHHHHHHH
LIIAMVQRGMKSAVILSILIITGLGLLFGDVHYNGIVSMPPSVAPTFMAMDLSQVFEVTM
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
TSYIESTAGVSAGGRTGLTAVVVGLLFILALFLSPLAGMIPAYATAGTLFYVAILMMAGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHVEWEDLTEAAPVVVVCILMPLTFSIATGIALGIISYAVIKLLTGRFSDLNIGVLVLAA
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
MFIAKFIYG
HHHHHHHCC
>Mature Secondary Structure
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GCIVMGVMANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPATLVTMGDITAFPAVMAVLGFF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECHHHHHHHHHHHHHHH
LIIAMVQRGMKSAVILSILIITGLGLLFGDVHYNGIVSMPPSVAPTFMAMDLSQVFEVTM
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
TSYIESTAGVSAGGRTGLTAVVVGLLFILALFLSPLAGMIPAYATAGTLFYVAILMMAGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHVEWEDLTEAAPVVVVCILMPLTFSIATGIALGIISYAVIKLLTGRFSDLNIGVLVLAA
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
MFIAKFIYG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]