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The map label for this gene is virS [H]

Identifier: 116696463

GI number: 116696463

Start: 2854169

End: 2855170

Strand: Direct

Name: virS [H]

Synonym: H16_B2527

Alternate gene names: 116696463

Gene position: 2854169-2855170 (Clockwise)

Preceding gene: 116696458

Following gene: 116696468

Centisome position: 98.0

GC content: 66.97

Gene sequence:

>1002_bases
ATGTCCTACTATCTGCGCAGCGCCAGCCTGACCAATTACGTGGAAGTCGCGCGTTCGCTGGGGCTCGATCCGTACCAGCA
ACTGAGGGCGGCAAAGATCAACCGCTCGGTCCTGCTCGATCCCGATATCCGCATCCCCGCGGCCTCGGTCGGCCGCTTGC
TGGATGCGTCGGCACACGCCACCGGGGCCGACGATTTCGGCCTGCGCATGGCCGAGCTGCGCGAGTTCTCCAACCTCGGC
CCGCTCGCCTTCGTGGTGCGTGAAGAGCCCACGCTGCGCCGCGCGCTGGAGTCGATGGTCCGCTACATGGGCCTGCAGAA
TGAATCGCTGTCGATGCGTATCGAAGACAGCGATGAACTGGTGATGATCCGGCTGCAGGTGCTCACCGAAGCGCCGGGCA
CCTTGCGGCAGGCCGCCGACCTCGCGGTCGGCGTGGTGTTCCGGATGCTGAGGCTGTTCCTGGGGCAGTCCTGGCGGCCG
CGCAGCATCTGCTTCACCCACCCCGCGCCGGCCAACGCGGCCACGTTTTCACGCGTGTTCGGCATGCCCTGCACCTTCAA
CCAGGATTTCGACGGCATCGTCTGCCTGGCCTCGGACCTGGAGGCGCCGTTGCCGTCGTATGACCCGGTGATGGCGCAGC
AGGTGAAGCACTATCTCGGCACGCTGCTGGCGCAGTCGACCGCGGCGACCATGTCGGACATGGTGCGCAAGCTGGTCTAT
GCGCTGCTGCCCACCGGACTGTGCTCGGTCGAACGCGTGGCCCAGCACCTGAGCGTCGACCGGCGCACCGTGCATCGGCG
GCTCGGGCAGGAACATACGACCTACTCCGACATCCTTGCCGAGGCCCGTGCCGACCTGGTAATCCGCTACCTGGAGAACC
GCGAGCGTCCGCTGTCGGAAGTGGCCGCGCTGCTGGGGTTTTCGTCGCTGAGCGCGTTCTCGCGGTGGTTCAGCGGGCGT
TTTGGGCGCAGCGTGTCGGCATGGCGGGCGCAGGCGGGGTAA

Upstream 100 bases:

>100_bases
TTAGTGGTTGGAGTATCGGTGAACGACCGGCCGCGATTTGACGATTGGGGACATCCGATTTACATTTCGGGACACTCAGG
GAAAGCACGGAATCCGCCCA

Downstream 100 bases:

>100_bases
TAGAGGAAAGGTTCTTTGCGAATTTGAGGGTGGTGGCTGTTGGCGGGTGTGGTTGATTGGGCTGTCGCTACGCGGTCGGT
TGTCGTTCTTGACTAGCGTG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSYYLRSASLTNYVEVARSLGLDPYQQLRAAKINRSVLLDPDIRIPAASVGRLLDASAHATGADDFGLRMAELREFSNLG
PLAFVVREEPTLRRALESMVRYMGLQNESLSMRIEDSDELVMIRLQVLTEAPGTLRQAADLAVGVVFRMLRLFLGQSWRP
RSICFTHPAPANAATFSRVFGMPCTFNQDFDGIVCLASDLEAPLPSYDPVMAQQVKHYLGTLLAQSTAATMSDMVRKLVY
ALLPTGLCSVERVAQHLSVDRRTVHRRLGQEHTTYSDILAEARADLVIRYLENRERPLSEVAALLGFSSLSAFSRWFSGR
FGRSVSAWRAQAG

Sequences:

>Translated_333_residues
MSYYLRSASLTNYVEVARSLGLDPYQQLRAAKINRSVLLDPDIRIPAASVGRLLDASAHATGADDFGLRMAELREFSNLG
PLAFVVREEPTLRRALESMVRYMGLQNESLSMRIEDSDELVMIRLQVLTEAPGTLRQAADLAVGVVFRMLRLFLGQSWRP
RSICFTHPAPANAATFSRVFGMPCTFNQDFDGIVCLASDLEAPLPSYDPVMAQQVKHYLGTLLAQSTAATMSDMVRKLVY
ALLPTGLCSVERVAQHLSVDRRTVHRRLGQEHTTYSDILAEARADLVIRYLENRERPLSEVAALLGFSSLSAFSRWFSGR
FGRSVSAWRAQAG
>Mature_332_residues
SYYLRSASLTNYVEVARSLGLDPYQQLRAAKINRSVLLDPDIRIPAASVGRLLDASAHATGADDFGLRMAELREFSNLGP
LAFVVREEPTLRRALESMVRYMGLQNESLSMRIEDSDELVMIRLQVLTEAPGTLRQAADLAVGVVFRMLRLFLGQSWRPR
SICFTHPAPANAATFSRVFGMPCTFNQDFDGIVCLASDLEAPLPSYDPVMAQQVKHYLGTLLAQSTAATMSDMVRKLVYA
LLPTGLCSVERVAQHLSVDRRTVHRRLGQEHTTYSDILAEARADLVIRYLENRERPLSEVAALLGFSSLSAFSRWFSGRF
GRSVSAWRAQAG

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37048; Mature: 36917

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYYLRSASLTNYVEVARSLGLDPYQQLRAAKINRSVLLDPDIRIPAASVGRLLDASAHA
CCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCC
TGADDFGLRMAELREFSNLGPLAFVVREEPTLRRALESMVRYMGLQNESLSMRIEDSDEL
CCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCE
VMIRLQVLTEAPGTLRQAADLAVGVVFRMLRLFLGQSWRPRSICFTHPAPANAATFSRVF
EEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHH
GMPCTFNQDFDGIVCLASDLEAPLPSYDPVMAQQVKHYLGTLLAQSTAATMSDMVRKLVY
CCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLPTGLCSVERVAQHLSVDRRTVHRRLGQEHTTYSDILAEARADLVIRYLENRERPLSE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
VAALLGFSSLSAFSRWFSGRFGRSVSAWRAQAG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SYYLRSASLTNYVEVARSLGLDPYQQLRAAKINRSVLLDPDIRIPAASVGRLLDASAHA
CCEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCC
TGADDFGLRMAELREFSNLGPLAFVVREEPTLRRALESMVRYMGLQNESLSMRIEDSDEL
CCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCE
VMIRLQVLTEAPGTLRQAADLAVGVVFRMLRLFLGQSWRPRSICFTHPAPANAATFSRVF
EEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHH
GMPCTFNQDFDGIVCLASDLEAPLPSYDPVMAQQVKHYLGTLLAQSTAATMSDMVRKLVY
CCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLPTGLCSVERVAQHLSVDRRTVHRRLGQEHTTYSDILAEARADLVIRYLENRERPLSE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
VAALLGFSSLSAFSRWFSGRFGRSVSAWRAQAG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]