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The map label for this gene is yafC [H]

Identifier: 116695723

GI number: 116695723

Start: 2027595

End: 2028614

Strand: Direct

Name: yafC [H]

Synonym: H16_B1787

Alternate gene names: 116695723

Gene position: 2027595-2028614 (Clockwise)

Preceding gene: 116695719

Following gene: 116695726

Centisome position: 69.62

GC content: 67.06

Gene sequence:

>1020_bases
ATGGTCACTTCGGCGCAGGCCACGGCCCGGACATCGACTTCTGCCAGTGGCGCACATATGATGGATACATCGCTTGATCC
GGTGCGGCCTGCGGTCGCAAGCAAAGAAATGAAACGGCAATTCGATGACCTTCAGCTTGGCAGCATCGAGCTGTTCTGCC
TGGCCGCGGAGCTGGGCAGTTTCACCGCGGCGGCAGTGGCCGCGGGCGTGACACCGCCCGCAGTCAGCCGCACTGTGCAA
AGGCTGGAAGAGCGCCTGGGGGTGCGGCTGTTCGTGCGGACCACGCGGCAGATCCGCCTGACCGACGAAGGCCGGGTGTA
TTTCGAGCAGAGCCGCGGCGCACTGGCGCAGCTGGTGGACGCGGAGCGGCAGATCAGCGGCCAGCAGGCTGCCCCCGCGG
GGCGCTTGCGGATCAGCCTGCCGACCCCTTACGCGCACTATCGCGTGCTGCCGGTGCTGCCGGCATTCCGCGAGCGCTAC
CCCGAGGTCGAGATCGACGTGCACATCAGCAACCGCAACGTGGATTTCGCCGATGACACCTATGACCTGTCGGTGCGCGG
GCGTGCGCCGGATGACTCGAACCTGATCGCGCGCAAGCTGGAAGACGCGGAGCTGGTGGTGGTGGCAACGCCTGGCTATC
TGCGGCGTGCCGGCACACCGCAGTCATTGGAGGACCTGCTCAGGCATGAGTGCATCCAGTTCGAGCGCCCGAGCAGCGGC
CGGCGGATCCCATGGACGTTCCGGGTCAACGGCGAGGACACGGATATCGTGACCGCCGGCTCGTATGCGGCGTCAGAAGA
CATCCTGGGCGGGGCCACGCTGGTGCGCGCCGGCGCGGGCCTGTTCCAGACCTACCGCTTCGTCGTGGAACAGGACCTGC
GCGACGGCACGCTGGTGGAGGTGCTGAAGGACTACGGCGGCAGTACGCGCCCCTTTGTGCTGCTGTACCCGTCCGCGCGC
CACGTCTCGCGCCGGGTACGGGCGTTCGTCGACTTCCTGGTCGAGAAGTTCTCGGCGTAG

Upstream 100 bases:

>100_bases
CGCTTCCGTATTCGAAGACCCTGGCGGCACAAACAGTCTTGCGCCACAAGCACAAATGGAGCGGGACGAATCCTCCGGCG
CGCCTGGCGTGCGCAGCCTC

Downstream 100 bases:

>100_bases
CGGCTCACGCCGCGCTTATTCAGGCCGGATCTGGGCAATGACCACGAGGATCACGGCCGCATTCGCCGGCTGCTGGAAGT
GCGAGGAAATGGTGCGCGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVTSAQATARTSTSASGAHMMDTSLDPVRPAVASKEMKRQFDDLQLGSIELFCLAAELGSFTAAAVAAGVTPPAVSRTVQ
RLEERLGVRLFVRTTRQIRLTDEGRVYFEQSRGALAQLVDAERQISGQQAAPAGRLRISLPTPYAHYRVLPVLPAFRERY
PEVEIDVHISNRNVDFADDTYDLSVRGRAPDDSNLIARKLEDAELVVVATPGYLRRAGTPQSLEDLLRHECIQFERPSSG
RRIPWTFRVNGEDTDIVTAGSYAASEDILGGATLVRAGAGLFQTYRFVVEQDLRDGTLVEVLKDYGGSTRPFVLLYPSAR
HVSRRVRAFVDFLVEKFSA

Sequences:

>Translated_339_residues
MVTSAQATARTSTSASGAHMMDTSLDPVRPAVASKEMKRQFDDLQLGSIELFCLAAELGSFTAAAVAAGVTPPAVSRTVQ
RLEERLGVRLFVRTTRQIRLTDEGRVYFEQSRGALAQLVDAERQISGQQAAPAGRLRISLPTPYAHYRVLPVLPAFRERY
PEVEIDVHISNRNVDFADDTYDLSVRGRAPDDSNLIARKLEDAELVVVATPGYLRRAGTPQSLEDLLRHECIQFERPSSG
RRIPWTFRVNGEDTDIVTAGSYAASEDILGGATLVRAGAGLFQTYRFVVEQDLRDGTLVEVLKDYGGSTRPFVLLYPSAR
HVSRRVRAFVDFLVEKFSA
>Mature_339_residues
MVTSAQATARTSTSASGAHMMDTSLDPVRPAVASKEMKRQFDDLQLGSIELFCLAAELGSFTAAAVAAGVTPPAVSRTVQ
RLEERLGVRLFVRTTRQIRLTDEGRVYFEQSRGALAQLVDAERQISGQQAAPAGRLRISLPTPYAHYRVLPVLPAFRERY
PEVEIDVHISNRNVDFADDTYDLSVRGRAPDDSNLIARKLEDAELVVVATPGYLRRAGTPQSLEDLLRHECIQFERPSSG
RRIPWTFRVNGEDTDIVTAGSYAASEDILGGATLVRAGAGLFQTYRFVVEQDLRDGTLVEVLKDYGGSTRPFVLLYPSAR
HVSRRVRAFVDFLVEKFSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=34.7222222222222, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=34.1216216216216, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=28.5223367697594, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=28.2828282828283, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787589, Length=302, Percent_Identity=28.476821192053, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789440, Length=280, Percent_Identity=29.6428571428571, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789173, Length=299, Percent_Identity=26.7558528428094, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788706, Length=191, Percent_Identity=29.3193717277487, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=39.4957983193277, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786448, Length=298, Percent_Identity=23.8255033557047, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=294, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787601, Length=181, Percent_Identity=23.7569060773481, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786508, Length=120, Percent_Identity=36.6666666666667, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082132, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693105, Length=124, Percent_Identity=30.6451612903226, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790011, Length=267, Percent_Identity=25.0936329588015, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788297, Length=121, Percent_Identity=30.5785123966942, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787879, Length=134, Percent_Identity=31.3432835820896, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37447; Mature: 37447

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSAQATARTSTSASGAHMMDTSLDPVRPAVASKEMKRQFDDLQLGSIELFCLAAELGS
CCCCCCCHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEHHCC
FTAAAVAAGVTPPAVSRTVQRLEERLGVRLFVRTTRQIRLTDEGRVYFEQSRGALAQLVD
HHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECEEEEEECCCCEEEECCCCHHHHHHH
AERQISGQQAAPAGRLRISLPTPYAHYRVLPVLPAFRERYPEVEIDVHISNRNVDFADDT
HHHHCCCCCCCCCCCEEEECCCCCHHEEEEECCHHHHHHCCCEEEEEEECCCCCCCCCCC
YDLSVRGRAPDDSNLIARKLEDAELVVVATPGYLRRAGTPQSLEDLLRHECIQFERPSSG
EEEEEECCCCCCCCHHHHHCCCCCEEEEECCHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
RRIPWTFRVNGEDTDIVTAGSYAASEDILGGATLVRAGAGLFQTYRFVVEQDLRDGTLVE
CCCCEEEEECCCCCCEEEECCCCCCCHHCCCHHHHHHCHHHHHHHHHHHHHCCCCCHHHH
VLKDYGGSTRPFVLLYPSARHVSRRVRAFVDFLVEKFSA
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTSAQATARTSTSASGAHMMDTSLDPVRPAVASKEMKRQFDDLQLGSIELFCLAAELGS
CCCCCCCHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEHHCC
FTAAAVAAGVTPPAVSRTVQRLEERLGVRLFVRTTRQIRLTDEGRVYFEQSRGALAQLVD
HHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECEEEEEECCCCEEEECCCCHHHHHHH
AERQISGQQAAPAGRLRISLPTPYAHYRVLPVLPAFRERYPEVEIDVHISNRNVDFADDT
HHHHCCCCCCCCCCCEEEECCCCCHHEEEEECCHHHHHHCCCEEEEEEECCCCCCCCCCC
YDLSVRGRAPDDSNLIARKLEDAELVVVATPGYLRRAGTPQSLEDLLRHECIQFERPSSG
EEEEEECCCCCCCCHHHHHCCCCCEEEEECCHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
RRIPWTFRVNGEDTDIVTAGSYAASEDILGGATLVRAGAGLFQTYRFVVEQDLRDGTLVE
CCCCEEEEECCCCCCEEEECCCCCCCHHCCCHHHHHHCHHHHHHHHHHHHHCCCCCHHHH
VLKDYGGSTRPFVLLYPSARHVSRRVRAFVDFLVEKFSA
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]