Definition Ralstonia eutropha H16 chromosome 2, complete sequence.
Accession NC_008314
Length 2,912,490

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The map label for this gene is yqjQ [H]

Identifier: 116695726

GI number: 116695726

Start: 2030364

End: 2031167

Strand: Direct

Name: yqjQ [H]

Synonym: H16_B1790

Alternate gene names: 116695726

Gene position: 2030364-2031167 (Clockwise)

Preceding gene: 116695723

Following gene: 116695727

Centisome position: 69.71

GC content: 67.66

Gene sequence:

>804_bases
ATGACCACGCACAACCATTCCGGCACCGCCCTCATCACCGGTGCTTCTTCCGGCATCGGCGCCATCTATGCGGAGCGCCT
GGCGCGCAGGGGCCACGACCTGATCCTGGTGGCGCGTAACCGCGCGCGGCTGGAAGCACTGGCCCGCCGGATTACCGACG
ATACCGGCCGCTCGGTCGAAATCGTGACCGCGGACCTTGGCCAGGCAGCCGATGTACGACGCATCGAAGAGATCCTGCGC
ACGGATGCAAGCATCACCACGCTGGTCAACAACGCCGGCTTCGGCGGCGCGGCACCGCTGCTGCAATCGGATGTCGACAC
CATGCAGGCAATGATCGAGCTCAACGTCACGGCGCTGACCCGGCTCACCTACGCCGCCGCCCCGGCGTTCGTTGCGCGCG
GCGAGGGCACCATCATCAATATCGCCTCGATCGTGGCGGTCGCGCCCGAGGTCCTGAACGGTGTCTACGGCGCCACCAAG
GCGTTTGTGCTGGCCTTTACCCAGTCGCTGCAACATGAGCTTGCGGGCAAGGGCGTGCGCATCCAGGCGGTCCTGCCGGG
GGCCACCCGCACCGAGTTCTGGGACACCGCCGGCCAGCCGGTCGAGAACCTGCCGCAATCGATAGTCATGAGCGGCGACG
ACCTGGTCGACGCGGCCCTGGCAGGGCTGGACCAGGGCGAGGTGATTACCGTGCCGTCGTTGCCCGACGTGGCCGACTGG
AACACGTTCGAGGCGGCACGCGCCGCGCTCGGCCCCAATCTTTCGCGTGACCAGCCCGCTACCCGGTACGGCGTTGCCCG
GTAA

Upstream 100 bases:

>100_bases
GTGCCAACGCCATTGTGCGCCTAATCTTGGCTTCACGCAGCCGGCCGATCCAGCGCCGACCGCCACCAACATCCCCCCTC
ACTGAATCTGGAGCTTTGAC

Downstream 100 bases:

>100_bases
CTGACGGCTCGCGGACGCGCGCGGCCTTTACACCACCTTCCCCGGGGCGCGCGGTATCCGGCAAGCGCTCCGGCCGCCGC
GCGCCTCCTCCCTGCCGCCT

Product: Short-chain dehydrogenase of various substrates pecificities

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTTHNHSGTALITGASSGIGAIYAERLARRGHDLILVARNRARLEALARRITDDTGRSVEIVTADLGQAADVRRIEEILR
TDASITTLVNNAGFGGAAPLLQSDVDTMQAMIELNVTALTRLTYAAAPAFVARGEGTIINIASIVAVAPEVLNGVYGATK
AFVLAFTQSLQHELAGKGVRIQAVLPGATRTEFWDTAGQPVENLPQSIVMSGDDLVDAALAGLDQGEVITVPSLPDVADW
NTFEAARAALGPNLSRDQPATRYGVAR

Sequences:

>Translated_267_residues
MTTHNHSGTALITGASSGIGAIYAERLARRGHDLILVARNRARLEALARRITDDTGRSVEIVTADLGQAADVRRIEEILR
TDASITTLVNNAGFGGAAPLLQSDVDTMQAMIELNVTALTRLTYAAAPAFVARGEGTIINIASIVAVAPEVLNGVYGATK
AFVLAFTQSLQHELAGKGVRIQAVLPGATRTEFWDTAGQPVENLPQSIVMSGDDLVDAALAGLDQGEVITVPSLPDVADW
NTFEAARAALGPNLSRDQPATRYGVAR
>Mature_266_residues
TTHNHSGTALITGASSGIGAIYAERLARRGHDLILVARNRARLEALARRITDDTGRSVEIVTADLGQAADVRRIEEILRT
DASITTLVNNAGFGGAAPLLQSDVDTMQAMIELNVTALTRLTYAAAPAFVARGEGTIINIASIVAVAPEVLNGVYGATKA
FVLAFTQSLQHELAGKGVRIQAVLPGATRTEFWDTAGQPVENLPQSIVMSGDDLVDAALAGLDQGEVITVPSLPDVADWN
TFEAARAALGPNLSRDQPATRYGVAR

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=186, Percent_Identity=39.247311827957, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI226371731, Length=180, Percent_Identity=32.7777777777778, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7705855, Length=188, Percent_Identity=31.9148936170213, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254992, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=30.6878306878307, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=30.1587301587302, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=29.2553191489362, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=28.042328042328, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=32.1243523316062, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI15277342, Length=238, Percent_Identity=31.0924369747899, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI225579078, Length=200, Percent_Identity=30.5, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150247226, Length=221, Percent_Identity=26.6968325791855, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI7705925, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787820, Length=245, Percent_Identity=31.4285714285714, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=30.5, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=207, Percent_Identity=32.3671497584541, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=31.8918918918919, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87082160, Length=185, Percent_Identity=26.4864864864865, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787526, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=201, Percent_Identity=30.3482587064677, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788459, Length=185, Percent_Identity=31.3513513513514, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=36.2694300518135, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=198, Percent_Identity=32.8282828282828, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557668, Length=198, Percent_Identity=30.8080808080808, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559552, Length=198, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=32.620320855615, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560176, Length=184, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25152911, Length=192, Percent_Identity=31.7708333333333, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI212646214, Length=190, Percent_Identity=30, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=231, Percent_Identity=31.6017316017316, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=205, Percent_Identity=32.1951219512195, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=30.9644670050761, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=30.2521008403361, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=201, Percent_Identity=31.3432835820896, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=208, Percent_Identity=30.2884615384615, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=243, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=201, Percent_Identity=29.3532338308458, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=214, Percent_Identity=29.4392523364486, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=199, Percent_Identity=30.1507537688442, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=26.4248704663212, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=201, Percent_Identity=28.8557213930348, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=37.17277486911, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319635, Length=187, Percent_Identity=29.9465240641711, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=203, Percent_Identity=25.615763546798, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=33.5106382978723, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=36.1702127659575, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24584748, Length=184, Percent_Identity=32.6086956521739, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI161076933, Length=184, Percent_Identity=32.6086956521739, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24584752, Length=187, Percent_Identity=32.620320855615, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=199, Percent_Identity=33.6683417085427, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=35.3846153846154, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=32.0855614973262, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=32.0855614973262, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=34.5549738219895, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007236, Length=210, Percent_Identity=30, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21358495, Length=187, Percent_Identity=29.9465240641711, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007238, Length=179, Percent_Identity=30.7262569832402, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639444, Length=185, Percent_Identity=31.8918918918919, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649181, Length=239, Percent_Identity=26.7782426778243, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641232, Length=197, Percent_Identity=29.4416243654822, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24665247, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221331216, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28079; Mature: 27948

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTTHNHSGTALITGASSGIGAIYAERLARRGHDLILVARNRARLEALARRITDDTGRSVE
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEEE
IVTADLGQAADVRRIEEILRTDASITTLVNNAGFGGAAPLLQSDVDTMQAMIELNVTALT
EEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLTYAAAPAFVARGEGTIINIASIVAVAPEVLNGVYGATKAFVLAFTQSLQHELAGKGVR
HHHHHHCCHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IQAVLPGATRTEFWDTAGQPVENLPQSIVMSGDDLVDAALAGLDQGEVITVPSLPDVADW
EEEECCCCCCHHHHCCCCCCHHHCCHHHHCCCCHHHHHHHHCCCCCCEEECCCCCCCCCC
NTFEAARAALGPNLSRDQPATRYGVAR
CHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTHNHSGTALITGASSGIGAIYAERLARRGHDLILVARNRARLEALARRITDDTGRSVE
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEEE
IVTADLGQAADVRRIEEILRTDASITTLVNNAGFGGAAPLLQSDVDTMQAMIELNVTALT
EEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLTYAAAPAFVARGEGTIINIASIVAVAPEVLNGVYGATKAFVLAFTQSLQHELAGKGVR
HHHHHHCCHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IQAVLPGATRTEFWDTAGQPVENLPQSIVMSGDDLVDAALAGLDQGEVITVPSLPDVADW
EEEECCCCCCHHHHCCCCCCHHHCCHHHHCCCCHHHHHHHHCCCCCCEEECCCCCCCCCC
NTFEAARAALGPNLSRDQPATRYGVAR
CHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]