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The map label for this gene is nodT [H]

Identifier: 116695719

GI number: 116695719

Start: 2023016

End: 2024494

Strand: Direct

Name: nodT [H]

Synonym: H16_B1783

Alternate gene names: 116695719

Gene position: 2023016-2024494 (Clockwise)

Preceding gene: 116695714

Following gene: 116695723

Centisome position: 69.46

GC content: 72.01

Gene sequence:

>1479_bases
ATGCCCCAAAGTCCATTCCGCCCCCCGCTCCGGCGCACCCGCGCCGGTATCGCCCGCCTCCTGCCCACCCTGCTTGCGGC
CAGCGCCGCGGCCGCCCTGGTGGCCTGCGCGGCCGGCCCCGATTACCACATGCCGGCCTCGGACATGCCCGCGGCCTACC
CGCACGCAGCGGCGCTGGACGCCCGCGAGGCCACGCAGCCCGCGCCGTCACTGGACAGCTGGTGGCTGGGCTTTGACGAT
CCCACGCTGACGCGCGTGATCCAGCGCGCGCTGGAGCAGAACCTCGACCTGGCGGCGGCGATTGCGCGGGTCGACCAGGC
CCGCGCCGCGGCCAGCCACGCCGGCGCCGAACTGCTGCCGCAGGCATCGTTGTCCGGCAGCGTGGCCAGGCAGCGCCAGT
CGCTGGAAGGGCCTTTGGGCAGCCTCGGCAAGAACGCGCCGGGCTTTGAGCGCAACAAGACGGTGTACAGCGCTGGTGTG
GGAGCAAGCTGGGAGATCGACGTGGCCGGCGGCCTGCGGCGCGGCGCCGAGGCCGCCAGCGCGGAGGCCCAGGCCGCGGA
AGCCGAGCACATGGGCGTGCGCGTGCTGGTAGCCGCCGAAGCGGCCGATGCCTACTTCCGCGTGCGCGGCGCGCAGCAGC
GCATCGCCATCGCGCAACAGCAGGTGCGGACCAATGCAAAGCTGCTCGAGCTGGTGCAGCTGCGGCTGGCCGATGGCATC
GGCGCCGAGCGGGAACGCGCGCAGGCGGAAGCACAGCTGGCACAGACCCGCGTGACCATCCCGCCGCTGCAGATCGAACT
GGAGACACAGCTGAACCGGCTCGATGTATTGATGGGCGCGCATCCGGGCACCTATGCCGCTGAACTCCTGACGCCGACCG
AGCGCACCGCCGTGCCGCAGATCGCCGTGGCGCAAGGTCCGGCCAACCTGCTGCAACGCCGCCCGGACGTGATTGCCGCG
GAGCGCCGGCTGGCGGCATCCAGTGCCCGCATCGGCGTGGCCACTGCCGAGTACTACCCGAAGCTGTCGCTGTCAGCGCT
GCTCGGCTTCGAGAGCCTCTCCGCCGGCAAGCTGTTCACCGGGTCCGCCTTCCAGCCCGCCGCGATCGCGGGACTGCGCT
GGCGGCTGTTCGACTTCGGCCGGGTCGATGCCGAAGTGGCGCAGGCCAAAGGCGCCAACGCCGAAGCCCTGGCCACCTAC
CGCAAGGCCATGCTGCGCGCCACCGAGGACGTGGAAAACGCGATCATCACGCTGACCCAGCTGGAGTTGCAGGGCAAGGA
GCTGACCGTGGAAGTGGCTGCCCACGCGCGCTCGCGCGGCGCCGCCGAGGACGCCTACAAGGGCGGCGCGGTCAGCCTGT
TCGAAGTGCTGGAGGAAGACCGCCTGCTGCTGGCCGCGCGCGACCAGCAGGCACGTGTGGGCGCCGACAATGCCCGCGCG
GCGGTGGCAACGTTCCGTGCGCTGGGGGGTGGCTGGTAA

Upstream 100 bases:

>100_bases
GGTTGCTATCAAATTGAAAGTTAGTCTAGAGTAGTAACTATCATCATGCAAGTTAGTTTTTGGCTTGTGCTTTATTCGTC
GCTGTTGAAAGGTGTCCGTC

Downstream 100 bases:

>100_bases
CGTAGCGGGCGGCGGCTCAACCCACCCTGAGCCGCGCCTCCAGGCCACCGCCCTCGCGATTGCGCAGCGTCAGTGAGCCG
CCGATGGCCAGCGCAAGCTG

Product: outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MPQSPFRPPLRRTRAGIARLLPTLLAASAAAALVACAAGPDYHMPASDMPAAYPHAAALDAREATQPAPSLDSWWLGFDD
PTLTRVIQRALEQNLDLAAAIARVDQARAAASHAGAELLPQASLSGSVARQRQSLEGPLGSLGKNAPGFERNKTVYSAGV
GASWEIDVAGGLRRGAEAASAEAQAAEAEHMGVRVLVAAEAADAYFRVRGAQQRIAIAQQQVRTNAKLLELVQLRLADGI
GAERERAQAEAQLAQTRVTIPPLQIELETQLNRLDVLMGAHPGTYAAELLTPTERTAVPQIAVAQGPANLLQRRPDVIAA
ERRLAASSARIGVATAEYYPKLSLSALLGFESLSAGKLFTGSAFQPAAIAGLRWRLFDFGRVDAEVAQAKGANAEALATY
RKAMLRATEDVENAIITLTQLELQGKELTVEVAAHARSRGAAEDAYKGGAVSLFEVLEEDRLLLAARDQQARVGADNARA
AVATFRALGGGW

Sequences:

>Translated_492_residues
MPQSPFRPPLRRTRAGIARLLPTLLAASAAAALVACAAGPDYHMPASDMPAAYPHAAALDAREATQPAPSLDSWWLGFDD
PTLTRVIQRALEQNLDLAAAIARVDQARAAASHAGAELLPQASLSGSVARQRQSLEGPLGSLGKNAPGFERNKTVYSAGV
GASWEIDVAGGLRRGAEAASAEAQAAEAEHMGVRVLVAAEAADAYFRVRGAQQRIAIAQQQVRTNAKLLELVQLRLADGI
GAERERAQAEAQLAQTRVTIPPLQIELETQLNRLDVLMGAHPGTYAAELLTPTERTAVPQIAVAQGPANLLQRRPDVIAA
ERRLAASSARIGVATAEYYPKLSLSALLGFESLSAGKLFTGSAFQPAAIAGLRWRLFDFGRVDAEVAQAKGANAEALATY
RKAMLRATEDVENAIITLTQLELQGKELTVEVAAHARSRGAAEDAYKGGAVSLFEVLEEDRLLLAARDQQARVGADNARA
AVATFRALGGGW
>Mature_491_residues
PQSPFRPPLRRTRAGIARLLPTLLAASAAAALVACAAGPDYHMPASDMPAAYPHAAALDAREATQPAPSLDSWWLGFDDP
TLTRVIQRALEQNLDLAAAIARVDQARAAASHAGAELLPQASLSGSVARQRQSLEGPLGSLGKNAPGFERNKTVYSAGVG
ASWEIDVAGGLRRGAEAASAEAQAAEAEHMGVRVLVAAEAADAYFRVRGAQQRIAIAQQQVRTNAKLLELVQLRLADGIG
AERERAQAEAQLAQTRVTIPPLQIELETQLNRLDVLMGAHPGTYAAELLTPTERTAVPQIAVAQGPANLLQRRPDVIAAE
RRLAASSARIGVATAEYYPKLSLSALLGFESLSAGKLFTGSAFQPAAIAGLRWRLFDFGRVDAEVAQAKGANAEALATYR
KAMLRATEDVENAIITLTQLELQGKELTVEVAAHARSRGAAEDAYKGGAVSLFEVLEEDRLLLAARDQQARVGADNARAA
VATFRALGGGW

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=472, Percent_Identity=27.5423728813559, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI2367348, Length=430, Percent_Identity=26.9767441860465, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51994; Mature: 51863

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSPFRPPLRRTRAGIARLLPTLLAASAAAALVACAAGPDYHMPASDMPAAYPHAAALD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCC
AREATQPAPSLDSWWLGFDDPTLTRVIQRALEQNLDLAAAIARVDQARAAASHAGAELLP
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCC
QASLSGSVARQRQSLEGPLGSLGKNAPGFERNKTVYSAGVGASWEIDVAGGLRRGAEAAS
CCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCCCCEEEECCCCHHCCCHHHH
AEAQAAEAEHMGVRVLVAAEAADAYFRVRGAQQRIAIAQQQVRTNAKLLELVQLRLADGI
HHHHHHHHHHCCEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAERERAQAEAQLAQTRVTIPPLQIELETQLNRLDVLMGAHPGTYAAELLTPTERTAVPQ
CCHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCCCC
IAVAQGPANLLQRRPDVIAAERRLAASSARIGVATAEYYPKLSLSALLGFESLSAGKLFT
EEECCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHCHHHCCCCCEEE
GSAFQPAAIAGLRWRLFDFGRVDAEVAQAKGANAEALATYRKAMLRATEDVENAIITLTQ
CCCCCCHHHHCCCCEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEE
LELQGKELTVEVAAHARSRGAAEDAYKGGAVSLFEVLEEDRLLLAARDQQARVGADNARA
EEECCCEEEEEEHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEEEECCCHHHCCCCCHHH
AVATFRALGGGW
HHHHHHHHCCCC
>Mature Secondary Structure 
PQSPFRPPLRRTRAGIARLLPTLLAASAAAALVACAAGPDYHMPASDMPAAYPHAAALD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCC
AREATQPAPSLDSWWLGFDDPTLTRVIQRALEQNLDLAAAIARVDQARAAASHAGAELLP
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCC
QASLSGSVARQRQSLEGPLGSLGKNAPGFERNKTVYSAGVGASWEIDVAGGLRRGAEAAS
CCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCCCCEEEECCCCHHCCCHHHH
AEAQAAEAEHMGVRVLVAAEAADAYFRVRGAQQRIAIAQQQVRTNAKLLELVQLRLADGI
HHHHHHHHHHCCEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAERERAQAEAQLAQTRVTIPPLQIELETQLNRLDVLMGAHPGTYAAELLTPTERTAVPQ
CCHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCCCC
IAVAQGPANLLQRRPDVIAAERRLAASSARIGVATAEYYPKLSLSALLGFESLSAGKLFT
EEECCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHCHHHCCCCCEEE
GSAFQPAAIAGLRWRLFDFGRVDAEVAQAKGANAEALATYRKAMLRATEDVENAIITLTQ
CCCCCCHHHHCCCCEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEE
LELQGKELTVEVAAHARSRGAAEDAYKGGAVSLFEVLEEDRLLLAARDQQARVGADNARA
EEECCCEEEEEEHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEEEECCCHHHCCCCCHHH
AVATFRALGGGW
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]